ATE111352T1 - Aerosole, die liposome beinhalten, und verfahren zu deren herstellung. - Google Patents

Aerosole, die liposome beinhalten, und verfahren zu deren herstellung.

Info

Publication number
ATE111352T1
ATE111352T1 AT87309854T AT87309854T ATE111352T1 AT E111352 T1 ATE111352 T1 AT E111352T1 AT 87309854 T AT87309854 T AT 87309854T AT 87309854 T AT87309854 T AT 87309854T AT E111352 T1 ATE111352 T1 AT E111352T1
Authority
AT
Austria
Prior art keywords
manufacture
processes
liposome
including liposomes
aerosols including
Prior art date
Application number
AT87309854T
Other languages
English (en)
Inventor
Jack Vernon Knight
Brian E Gilbert
Samuel Z Wilson
Howard R Six
Philip R Wyde
Original Assignee
Res Dev Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Dev Foundation filed Critical Res Dev Foundation
Application granted granted Critical
Publication of ATE111352T1 publication Critical patent/ATE111352T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Measurement Of Force In General (AREA)
  • Control Of Driving Devices And Active Controlling Of Vehicle (AREA)
  • Cosmetics (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
AT87309854T 1986-11-06 1987-11-06 Aerosole, die liposome beinhalten, und verfahren zu deren herstellung. ATE111352T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US92789886A 1986-11-06 1986-11-06

Publications (1)

Publication Number Publication Date
ATE111352T1 true ATE111352T1 (de) 1994-09-15

Family

ID=25455423

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87309854T ATE111352T1 (de) 1986-11-06 1987-11-06 Aerosole, die liposome beinhalten, und verfahren zu deren herstellung.

Country Status (16)

Country Link
EP (1) EP0267050B1 (de)
JP (1) JP2933931B2 (de)
KR (1) KR910004580B1 (de)
AT (1) ATE111352T1 (de)
AU (1) AU600766B2 (de)
CA (1) CA1263310A (de)
DE (1) DE3750537T2 (de)
DK (1) DK582487A (de)
ES (1) ES2058124T3 (de)
FI (1) FI874895A (de)
HK (1) HK1006679A1 (de)
IE (1) IE63869B1 (de)
IL (1) IL84360A (de)
NO (1) NO874600L (de)
NZ (1) NZ222433A (de)
PT (1) PT86090B (de)

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AU614527B2 (en) * 1987-07-24 1991-09-05 Nexstar Pharmaceuticals, Inc. Opioid analgesic liposomal delivery-release system
JPH03501253A (ja) * 1987-09-22 1991-03-22 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア エイズ(aids)治療を目的とするリポソームによるヌクレオシド類似物質
US5028697A (en) * 1988-08-08 1991-07-02 Eli Lilly And Company Cytotoxic antibody conjugates of hydrazide derivatized methotrexate analogs via simple organic linkers
IT1240353B (it) * 1990-03-30 1993-12-07 Poli Ind Chimica Spa Formulazioni liposomiali di farmaci immunomodulatori per applicazionelocale ed aerosolica
EP0706374B1 (de) * 1993-06-30 1997-12-10 Genentech, Inc. Verfahren zur herstellung von liposomen
ATE223202T1 (de) * 1994-09-30 2002-09-15 Mika Pharma Ges Fuer Die Entwi Pharmazeutische zusammensetzung
US5891465A (en) * 1996-05-14 1999-04-06 Biozone Laboratories, Inc. Delivery of biologically active material in a liposomal formulation for administration into the mouth
TW497974B (en) * 1996-07-03 2002-08-11 Res Dev Foundation High dose liposomal aerosol formulations
US6517860B1 (en) 1996-12-31 2003-02-11 Quadrant Holdings Cambridge, Ltd. Methods and compositions for improved bioavailability of bioactive agents for mucosal delivery
WO1998055104A1 (fr) * 1997-06-06 1998-12-10 Shionogi & Co., Ltd. Perfectionnement d'un systeme d'administration de medicament
KR20010041623A (ko) 1998-03-05 2001-05-25 니뽄 신야쿠 가부시키가이샤 흡입 투여용 지방 유제
US6251425B1 (en) 1998-10-02 2001-06-26 Igen, Inc. Glucoside paucilamellar vesicles
ES2341532T3 (es) * 1999-05-27 2010-06-22 Euro-Celtique S.A. Preparacion con povidona yodada para el tratamiento de heridas.
US7300667B1 (en) 1999-05-27 2007-11-27 Euro-Celtique, S.A. Preparations for the application of anti-inflammatory, especially antiseptic agents and/or agents promoting the healing of wounds, to the lower respiratory tract
CA2368192A1 (en) * 1999-05-27 2000-12-07 Wolfgang Fleischer Preparations for the application of antiseptic agents to the interior of the human or animal body
US6576224B1 (en) 1999-07-06 2003-06-10 Sinuspharma, Inc. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
NZ523693A (en) * 2000-07-10 2004-08-27 Chiron Corp Macrolide formulations for inhalation and methods of treatment of endobronchial infections
KR100989647B1 (ko) 2001-09-24 2010-10-26 오레곤 헬스 앤드 사이언스 유니버시티 식습관의 변화
US8058233B2 (en) 2002-01-10 2011-11-15 Oregon Health And Science University Modification of feeding behavior using PYY and GLP-1
PL211979B1 (pl) 2002-04-26 2012-07-31 Gilead Sciences Pochodne fosfonianowe, ich zastosowanie w leczeniu zakażenia wirusem HIV i chorób wpływających na białe krwinki, oraz kompozycje farmaceutyczne zawierające te związki
GB0300571D0 (en) 2003-01-10 2003-02-12 Imp College Innovations Ltd Modification of feeding behaviour
US7452901B2 (en) 2003-04-25 2008-11-18 Gilead Sciences, Inc. Anti-cancer phosphonate analogs
US7470724B2 (en) 2003-04-25 2008-12-30 Gilead Sciences, Inc. Phosphonate compounds having immuno-modulatory activity
US7300924B2 (en) 2003-04-25 2007-11-27 Gilead Sciences, Inc. Anti-infective phosphonate analogs
WO2005002626A2 (en) 2003-04-25 2005-01-13 Gilead Sciences, Inc. Therapeutic phosphonate compounds
US7427636B2 (en) 2003-04-25 2008-09-23 Gilead Sciences, Inc. Inosine monophosphate dehydrogenase inhibitory phosphonate compounds
MXPA05011296A (es) 2003-04-25 2006-01-24 Gilead Sciences Inc Conjugados de fosfonato inhibidores de la cinasa.
US7432261B2 (en) 2003-04-25 2008-10-07 Gilead Sciences, Inc. Anti-inflammatory phosphonate compounds
US7407965B2 (en) 2003-04-25 2008-08-05 Gilead Sciences, Inc. Phosphonate analogs for treating metabolic diseases
WO2004096286A2 (en) 2003-04-25 2004-11-11 Gilead Sciences, Inc. Antiviral phosphonate analogs
US7432273B2 (en) 2003-10-24 2008-10-07 Gilead Sciences, Inc. Phosphonate analogs of antimetabolites
EP1678321A1 (de) 2003-10-24 2006-07-12 Gilead Sciences, Inc. Verfahren und zusammensetzungen zur identifizierung therapeutischer verbindungen
US7427624B2 (en) 2003-10-24 2008-09-23 Gilead Sciences, Inc. Purine nucleoside phosphorylase inhibitory phosphonate compounds
US7432272B2 (en) 2003-12-22 2008-10-07 Gilead Sciences, Inc. Antiviral analogs
WO2006110157A2 (en) 2004-07-27 2006-10-19 Gilead Sciences, Inc. Nucleoside phosphonate conjugates as anti hiv agents
TWI428346B (zh) 2006-12-13 2014-03-01 Imp Innovations Ltd 新穎化合物及其等對進食行為影響
US10251839B2 (en) 2008-01-22 2019-04-09 Igi Laboratories, Inc. Lipid vesicles derived from olive oil fatty acids
WO2009143011A1 (en) * 2008-05-20 2009-11-26 Novartis Ag Antiviral compositions, methods of making and using such compositions, and systems for pulmonary delivery of such compositions
PL2307435T3 (pl) 2008-07-08 2012-11-30 Gilead Sciences Inc Sole związków inhibitorów HIV
PL3661937T3 (pl) 2017-08-01 2021-12-20 Gilead Sciences, Inc. Formy krystaliczne ((s)-((((2r,5r)-5-(6-amino-9h-puryn-9-ylo)-4-fluoro-2,5-dihydrofuran-2-ylo)oksy)metylo)(fenoksy)fosforylo)-l-alaninianu etylu (gs-9131) do leczenia zakażeń wirusowych
KR20210003197A (ko) 2018-04-23 2021-01-11 티엘씨 바이오파머슈티컬즈 인코포레이티드 폐 질환 치료에 사용하기 위한 흡입 가능한 리포솜 서방형 조성물

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3594476A (en) * 1969-05-12 1971-07-20 Massachusetts Inst Technology Submicron aqueous aerosols containing lecithin
FR2543018B1 (fr) * 1983-03-22 1985-07-26 Oreal Procede de preparation de vesicules lipidiques par vaporisation de solvants
GB8322178D0 (en) * 1983-08-17 1983-09-21 Sterwin Ag Preparing aerosol compositions
EP0158441B2 (de) * 1984-03-08 2001-04-04 Phares Pharmaceutical Research N.V. Liposombildende Zusammensetzung
DE3582905D1 (de) * 1984-08-10 1991-06-27 Syntex Inc Stabile liposome mit wasserloeslichen arzneimitteln.
GB8423436D0 (en) * 1984-09-17 1984-10-24 Riker Laboratories Inc Preparation of liposomes
GB8501015D0 (en) * 1985-01-16 1985-02-20 Riker Laboratories Inc Drug
GB8502892D0 (en) * 1985-02-05 1985-03-06 Sterwin Ag Aerosol composition
DE3686025T2 (de) * 1985-05-22 1993-01-07 Liposome Technology Inc Verfahren und system zum einatmen von liposomen.
GB8522964D0 (en) * 1985-09-17 1985-10-23 Biocompatibles Ltd Aerosol

Also Published As

Publication number Publication date
IL84360A (en) 1992-01-15
JP2933931B2 (ja) 1999-08-16
JPS63211223A (ja) 1988-09-02
ES2058124T3 (es) 1994-11-01
DE3750537D1 (de) 1994-10-20
DE3750537T2 (de) 1995-01-12
EP0267050A3 (en) 1988-10-26
DK582487D0 (da) 1987-11-05
IE63869B1 (en) 1995-06-14
EP0267050A2 (de) 1988-05-11
KR880005921A (ko) 1988-07-21
AU8081987A (en) 1988-06-02
NO874600L (no) 1988-05-09
NZ222433A (en) 1990-09-26
IE872938L (en) 1988-05-06
HK1006679A1 (en) 1999-03-12
PT86090A (en) 1987-12-01
NO874600D0 (no) 1987-11-04
AU600766B2 (en) 1990-08-23
IL84360A0 (en) 1988-04-29
DK582487A (da) 1988-05-07
FI874895A (fi) 1988-05-07
PT86090B (pt) 1990-11-20
FI874895A0 (fi) 1987-11-05
KR910004580B1 (ko) 1991-07-06
EP0267050B1 (de) 1994-09-14
CA1263310A (en) 1989-11-28

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time