KR880005921A - 의약용 소입자 에어로졸 리포좀 및 의약용 리포좀-약제 조합물 - Google Patents

의약용 소입자 에어로졸 리포좀 및 의약용 리포좀-약제 조합물

Info

Publication number
KR880005921A
KR880005921A KR1019870012472A KR870012472A KR880005921A KR 880005921 A KR880005921 A KR 880005921A KR 1019870012472 A KR1019870012472 A KR 1019870012472A KR 870012472 A KR870012472 A KR 870012472A KR 880005921 A KR880005921 A KR 880005921A
Authority
KR
South Korea
Prior art keywords
pharmaceutical
liposome
small particle
drug combinations
particle aerosol
Prior art date
Application number
KR1019870012472A
Other languages
English (en)
Other versions
KR910004580B1 (ko
Inventor
베르논 나이트 잭
이. 길버트 브라이안
젵. 윌슨 사무엘
알. 식스 호워드
알. 와이드 필립
Original Assignee
리서취 디벨노프맨트 파운데이션
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 리서취 디벨노프맨트 파운데이션 filed Critical 리서취 디벨노프맨트 파운데이션
Publication of KR880005921A publication Critical patent/KR880005921A/ko
Application granted granted Critical
Publication of KR910004580B1 publication Critical patent/KR910004580B1/ko

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Measurement Of Force In General (AREA)
  • Control Of Driving Devices And Active Controlling Of Vehicle (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
KR1019870012472A 1986-11-06 1987-11-06 의약용 소입자 에어로졸 리포좀 및 의약용 리포좀-약제 조합물 KR910004580B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92789886A 1986-11-06 1986-11-06
US927,.898 1986-11-06

Publications (2)

Publication Number Publication Date
KR880005921A true KR880005921A (ko) 1988-07-21
KR910004580B1 KR910004580B1 (ko) 1991-07-06

Family

ID=25455423

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019870012472A KR910004580B1 (ko) 1986-11-06 1987-11-06 의약용 소입자 에어로졸 리포좀 및 의약용 리포좀-약제 조합물

Country Status (16)

Country Link
EP (1) EP0267050B1 (ko)
JP (1) JP2933931B2 (ko)
KR (1) KR910004580B1 (ko)
AT (1) ATE111352T1 (ko)
AU (1) AU600766B2 (ko)
CA (1) CA1263310A (ko)
DE (1) DE3750537T2 (ko)
DK (1) DK582487A (ko)
ES (1) ES2058124T3 (ko)
FI (1) FI874895A (ko)
HK (1) HK1006679A1 (ko)
IE (1) IE63869B1 (ko)
IL (1) IL84360A (ko)
NO (1) NO874600L (ko)
NZ (1) NZ222433A (ko)
PT (1) PT86090B (ko)

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AU614527B2 (en) * 1987-07-24 1991-09-05 Nexstar Pharmaceuticals, Inc. Opioid analgesic liposomal delivery-release system
EP0380558A4 (en) * 1987-09-22 1991-07-31 The Regents Of The University Of California Liposomal nucleoside analogues for treating aids
US5028697A (en) * 1988-08-08 1991-07-02 Eli Lilly And Company Cytotoxic antibody conjugates of hydrazide derivatized methotrexate analogs via simple organic linkers
IT1240353B (it) * 1990-03-30 1993-12-07 Poli Ind Chimica Spa Formulazioni liposomiali di farmaci immunomodulatori per applicazionelocale ed aerosolica
EP0706374B1 (en) * 1993-06-30 1997-12-10 Genentech, Inc. Method for preparing liposomes
DE19536245A1 (de) * 1994-09-30 1996-04-04 Juergen Dr Regenold Pharmazeutische Zusammensetzung
US5891465A (en) * 1996-05-14 1999-04-06 Biozone Laboratories, Inc. Delivery of biologically active material in a liposomal formulation for administration into the mouth
TW497974B (en) * 1996-07-03 2002-08-11 Res Dev Foundation High dose liposomal aerosol formulations
US6517860B1 (en) 1996-12-31 2003-02-11 Quadrant Holdings Cambridge, Ltd. Methods and compositions for improved bioavailability of bioactive agents for mucosal delivery
AU7454698A (en) * 1997-06-06 1998-12-21 Shionogi & Co., Ltd. Improvement in medicament administration system
WO1999044594A1 (fr) * 1998-03-05 1999-09-10 Nippon Shinyaku Co., Ltd. Emulsions huileuses destinees a etre administrees par inhalation
US6251425B1 (en) 1998-10-02 2001-06-26 Igen, Inc. Glucoside paucilamellar vesicles
AU775500B2 (en) 1999-05-27 2004-08-05 Euro-Celtique S.A. Preparations for the application of anti-infective and/or anti-inflammatory agents
CA2368192A1 (en) * 1999-05-27 2000-12-07 Wolfgang Fleischer Preparations for the application of antiseptic agents to the interior of the human or animal body
US7300667B1 (en) 1999-05-27 2007-11-27 Euro-Celtique, S.A. Preparations for the application of anti-inflammatory, especially antiseptic agents and/or agents promoting the healing of wounds, to the lower respiratory tract
US6576224B1 (en) 1999-07-06 2003-06-10 Sinuspharma, Inc. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
NZ523693A (en) * 2000-07-10 2004-08-27 Chiron Corp Macrolide formulations for inhalation and methods of treatment of endobronchial infections
DE60230818D1 (de) 2001-09-24 2009-02-26 Imp Innovations Ltd Pyy3-36 zur zur reduzierung oder vorbeugung von fettleibigkeit
US8058233B2 (en) 2002-01-10 2011-11-15 Oregon Health And Science University Modification of feeding behavior using PYY and GLP-1
US20070010489A1 (en) 2002-04-26 2007-01-11 Arimilli Murty N Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds
GB0300571D0 (en) 2003-01-10 2003-02-12 Imp College Innovations Ltd Modification of feeding behaviour
US7470724B2 (en) 2003-04-25 2008-12-30 Gilead Sciences, Inc. Phosphonate compounds having immuno-modulatory activity
US7300924B2 (en) 2003-04-25 2007-11-27 Gilead Sciences, Inc. Anti-infective phosphonate analogs
WO2004096287A2 (en) 2003-04-25 2004-11-11 Gilead Sciences, Inc. Inosine monophosphate dehydrogenase inhibitory phosphonate compounds
US7452901B2 (en) 2003-04-25 2008-11-18 Gilead Sciences, Inc. Anti-cancer phosphonate analogs
US7432261B2 (en) 2003-04-25 2008-10-07 Gilead Sciences, Inc. Anti-inflammatory phosphonate compounds
JP2006524710A (ja) 2003-04-25 2006-11-02 ギリアード サイエンシーズ, インコーポレイテッド キナーゼインヒビターホスホネート抱合体
US7407965B2 (en) 2003-04-25 2008-08-05 Gilead Sciences, Inc. Phosphonate analogs for treating metabolic diseases
WO2005002626A2 (en) 2003-04-25 2005-01-13 Gilead Sciences, Inc. Therapeutic phosphonate compounds
NZ542342A (en) 2003-04-25 2009-05-31 Gilead Sciences Inc Antiviral phosphonate analogs
WO2005044308A1 (en) * 2003-10-24 2005-05-19 Gilead Sciences, Inc. Phosphonate analogs of antimetabolites
AU2004286239A1 (en) 2003-10-24 2005-05-12 Gilead Sciences, Inc. Methods and compositions for identifying therapeutic compounds
US7427624B2 (en) 2003-10-24 2008-09-23 Gilead Sciences, Inc. Purine nucleoside phosphorylase inhibitory phosphonate compounds
KR20060127906A (ko) 2003-12-22 2006-12-13 길리애드 사이언시즈, 인코포레이티드 4'-치환된 카보버와 아바카비어 유도체 및 hiv와 hcv항바이러스 활성을 갖는 관련 화합물
EP3539546A1 (en) 2004-07-27 2019-09-18 Gilead Sciences, Inc. Phosphonate analogs of hiv inhibitor compounds
TWI428346B (zh) 2006-12-13 2014-03-01 Imp Innovations Ltd 新穎化合物及其等對進食行為影響
US10251839B2 (en) 2008-01-22 2019-04-09 Igi Laboratories, Inc. Lipid vesicles derived from olive oil fatty acids
WO2009143011A1 (en) * 2008-05-20 2009-11-26 Novartis Ag Antiviral compositions, methods of making and using such compositions, and systems for pulmonary delivery of such compositions
AU2009268681B2 (en) 2008-07-08 2014-10-02 Gilead Sciences, Inc. Salts of HIV inhibitor compounds
ES2969496T3 (es) 2017-08-01 2024-05-20 Gilead Sciences Inc Formas cristalinas de ((S)-((((2R,5R)-5-(6-amino-9H-purin-9-il)-4-fluoro-2,5-dihidrofuran-2- il)oxi)metil)(fenoxi)fosforil)-L-alaninato de etilo para tratar infecciones virales
CA3101102A1 (en) 2018-04-23 2019-10-31 Tlc Biopharmaceuticals, Inc. Inhalable liposomal sustained release composition for use in treating pulmonary diseases

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3594476A (en) * 1969-05-12 1971-07-20 Massachusetts Inst Technology Submicron aqueous aerosols containing lecithin
FR2543018B1 (fr) * 1983-03-22 1985-07-26 Oreal Procede de preparation de vesicules lipidiques par vaporisation de solvants
GB8322178D0 (en) * 1983-08-17 1983-09-21 Sterwin Ag Preparing aerosol compositions
JPH0753661B2 (ja) * 1984-03-08 1995-06-07 フアレス フアーマスーチカル リサーチ エヌブイ プロ―リポソーム組成物及びリポソームの水性分散物を作る方法
EP0172007B1 (en) * 1984-08-10 1991-05-22 Syntex (U.S.A.) Inc. Stable liposomes with aqueous-soluble medicaments and methods for their preparation
GB8423436D0 (en) * 1984-09-17 1984-10-24 Riker Laboratories Inc Preparation of liposomes
GB8501015D0 (en) * 1985-01-16 1985-02-20 Riker Laboratories Inc Drug
GB8502892D0 (en) * 1985-02-05 1985-03-06 Sterwin Ag Aerosol composition
EP0223831B1 (en) * 1985-05-22 1992-07-15 Liposome Technology, Inc. Liposome inhalation method and system
GB8522964D0 (en) * 1985-09-17 1985-10-23 Biocompatibles Ltd Aerosol

Also Published As

Publication number Publication date
FI874895A0 (fi) 1987-11-05
PT86090A (en) 1987-12-01
EP0267050A3 (en) 1988-10-26
HK1006679A1 (en) 1999-03-12
DK582487A (da) 1988-05-07
AU8081987A (en) 1988-06-02
ATE111352T1 (de) 1994-09-15
EP0267050A2 (en) 1988-05-11
JPS63211223A (ja) 1988-09-02
DE3750537D1 (de) 1994-10-20
ES2058124T3 (es) 1994-11-01
NO874600D0 (no) 1987-11-04
EP0267050B1 (en) 1994-09-14
IE63869B1 (en) 1995-06-14
AU600766B2 (en) 1990-08-23
IE872938L (en) 1988-05-06
FI874895A (fi) 1988-05-07
DK582487D0 (da) 1987-11-05
JP2933931B2 (ja) 1999-08-16
DE3750537T2 (de) 1995-01-12
PT86090B (pt) 1990-11-20
KR910004580B1 (ko) 1991-07-06
NO874600L (no) 1988-05-09
NZ222433A (en) 1990-09-26
IL84360A (en) 1992-01-15
IL84360A0 (en) 1988-04-29
CA1263310A (en) 1989-11-28

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