ES2056837T3 - Procedimiento para preparar una composicion oral farmaceutica de liberacion controlada. - Google Patents

Procedimiento para preparar una composicion oral farmaceutica de liberacion controlada.

Info

Publication number
ES2056837T3
ES2056837T3 ES87830347T ES87830347T ES2056837T3 ES 2056837 T3 ES2056837 T3 ES 2056837T3 ES 87830347 T ES87830347 T ES 87830347T ES 87830347 T ES87830347 T ES 87830347T ES 2056837 T3 ES2056837 T3 ES 2056837T3
Authority
ES
Spain
Prior art keywords
preparing
procedure
controlled release
oral composition
release pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87830347T
Other languages
English (en)
Inventor
Roberto Valducci
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2056837T3 publication Critical patent/ES2056837T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pens And Brushes (AREA)
  • External Artificial Organs (AREA)
  • Cosmetics (AREA)
  • Silicon Polymers (AREA)
  • Color Television Systems (AREA)
  • Inks, Pencil-Leads, Or Crayons (AREA)
  • Laminated Bodies (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
  • Paints Or Removers (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)

Abstract

SE PROPORCIONA UNA MEMBRANA DE REVESTIMIENTO PARA COMPUESTOS FARMACEUTICOS, VETERINARIOS, COSMETICOS SINTETICOS Y EXTRACTIVOS, QUE COMPRENDE UNA SUSTANCIA LIPOFILA, SOLA O EN MEZCLA CON UN AGENTE DE ENDURECIMIENTO, DONDE LA SUSTANCIA LIPOFILA SE ELIGE DE ACIDOS GRASOS DE 12 A 20 ATOMOS DE CARBONO Y PARAFINA, Y EL ENDURECEDOR SE ELIGE DE ETERES O ESTERES DE CELULOSA, COPOLIMEROS DE ACIDO METACRILICO, POLIETILENGLICOL, POLIVINILPIRROLIDONA, POLIVINILACTOFTALATO Y POLIVINILACETATO.
ES87830347T 1986-09-30 1987-09-29 Procedimiento para preparar una composicion oral farmaceutica de liberacion controlada. Expired - Lifetime ES2056837T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT03530/86A IT1200217B (it) 1986-09-30 1986-09-30 Membrana per uso farmaceutico ed industriale

Publications (1)

Publication Number Publication Date
ES2056837T3 true ES2056837T3 (es) 1994-10-16

Family

ID=11109126

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87830347T Expired - Lifetime ES2056837T3 (es) 1986-09-30 1987-09-29 Procedimiento para preparar una composicion oral farmaceutica de liberacion controlada.

Country Status (18)

Country Link
US (1) US5149542A (es)
EP (1) EP0263083B1 (es)
JP (1) JP2518882B2 (es)
KR (1) KR880701542A (es)
CN (1) CN1062444C (es)
AT (1) ATE90871T1 (es)
AU (1) AU602931B2 (es)
CA (1) CA1313132C (es)
DE (1) DE3786316T2 (es)
DK (1) DK174949B1 (es)
ES (1) ES2056837T3 (es)
FI (1) FI882524A0 (es)
HU (1) HU201684B (es)
IT (1) IT1200217B (es)
NZ (1) NZ221987A (es)
PT (1) PT85819B (es)
WO (1) WO1988002253A1 (es)
ZA (1) ZA877316B (es)

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FR2581541B1 (fr) * 1985-05-09 1988-05-20 Rhone Poulenc Sante Nouvelles compositions pharmaceutiques permettant la liberation prolongee d'un principe actif et leur procede de preparation
IT1197316B (it) * 1986-10-01 1988-11-30 Proter Spa Formulazione galenica ad uso orale di derivati della reina a lento rilascio per impiego terapeutico
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DE3737741A1 (de) * 1987-11-06 1989-05-18 Goedecke Ag Oral anzuwendende arzneiform zur einmal taeglichen behandlung der hypertonie mit diltiazemhydrochlorid
DE3922167A1 (de) * 1988-04-16 1991-01-17 Sanol Arznei Schwarz Gmbh Oral zu verabreichende diltiazemhydrochlorid enthaltende pharmazeutische zubereitung zur einmal taeglichen applikation und verfahren zu deren herstellung
US5344657A (en) * 1988-04-27 1994-09-06 Elf Sanofi Microbeads of diltiazem, a process for their manufacture and a substained-release pharmaceutical composition containing them
DE3822095A1 (de) * 1988-06-30 1990-01-04 Klinge Co Chem Pharm Fab Neue arzneimittelformulierung sowie verfahren zu deren herstellung
IT1226940B (it) * 1988-09-16 1991-02-22 Recordati Chem Pharm Sistema terapeutico a rilascio controllato per formulazioni farmaceutiche liquide
US5296236A (en) * 1988-09-16 1994-03-22 Recordati S.A., Chemical And Pharmaceutical Company Controlled release therapeutic system for a liquid pharmaceutical formulations
US4956182A (en) * 1989-03-16 1990-09-11 Bristol-Myers Company Direct compression cholestyramine tablet and solvent-free coating therefor
US5133974A (en) * 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
US4966770A (en) * 1989-07-26 1990-10-30 Himedics, Inc. Prednisone microencapsulated granules
WO1992001446A1 (en) * 1990-07-20 1992-02-06 Aps Research Limited Sustained-release formulations
DE4031881C2 (de) * 1990-10-08 1994-02-24 Sanol Arznei Schwarz Gmbh Lösungsmittelfreie, oral zu verabreichende pharmazeutische Zubereitung mit verzögerter Wirkstoffreisetzung und Verfahren zu deren Herstellung
ZA923474B (en) * 1991-05-20 1993-01-27 Marion Merrell Dow Inc Diltiazem formulation
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GB2258613B (en) * 1991-08-12 1996-01-10 Euro Celtique Sa Pharmaceutical diltiazem formulation
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WO1993017673A1 (en) * 1992-03-03 1993-09-16 Top Gold Pty., Limited Sustained release analgesics
DE4313726A1 (de) * 1993-04-27 1994-11-03 Byk Nederland Bv Feste Darreichungsform
US5834024A (en) * 1995-01-05 1998-11-10 Fh Faulding & Co. Limited Controlled absorption diltiazem pharmaceutical formulation
US5567441A (en) * 1995-03-24 1996-10-22 Andrx Pharmaceuticals Inc. Diltiazem controlled release formulation
ATE283038T1 (de) * 1995-07-21 2004-12-15 Daiichi Seiyaku Co Verfahren zu herstellung einer granulären zubereitung
FR2742660B1 (fr) * 1995-12-22 1998-04-03 Ethypharm Lab Prod Ethiques Nouvelles formes de microgranules a liberation prolongee contenant du diltiazem comme principe actif
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
US5830503A (en) * 1996-06-21 1998-11-03 Andrx Pharmaceuticals, Inc. Enteric coated diltiazem once-a-day formulation
BR9711585A (pt) * 1996-10-01 2000-01-18 Cima Labs Inc Composição de microcápsula, com sabor mascarado, de um remédio solúvel em água, formulação farmacêutica para administrar um remédio, e, processo para disfarçar o sabor de um remédio.
KR100522248B1 (ko) * 1997-05-29 2006-02-01 동아제약주식회사 이중제어방출막구조의경구서방성제제및그제조방법
JP3950175B2 (ja) * 1997-05-30 2007-07-25 オスモティカ・コーポレイション 多層浸透デバイス
US6197347B1 (en) * 1998-06-29 2001-03-06 Andrx Pharmaceuticals, Inc. Oral dosage for the controlled release of analgesic
US6524620B2 (en) 1998-07-20 2003-02-25 Andrx Pharmaceuticals, Inc. Diltiazem controlled release formulation and method of manufacture
WO2000022909A2 (en) * 1998-10-19 2000-04-27 Biotech Australia Pty. Limited Systems for oral delivery
WO2000024423A1 (fr) * 1998-10-26 2000-05-04 Tanabe Seiyaku Co., Ltd. Particules a liberation prolongee
JP2000198747A (ja) * 1998-10-26 2000-07-18 Tanabe Seiyaku Co Ltd 徐放性粒子
FR2795962B1 (fr) * 1999-07-08 2003-05-09 Prographarm Laboratoires Procede de fabrication de granules enrobes a gout masque et liberation immediate du principe actif
US7108866B1 (en) 1999-12-10 2006-09-19 Biovall Laboratories International Srl Chronotherapeutic diltiazem formulations and the administration thereof
US20060153914A1 (en) * 1999-12-10 2006-07-13 Biovail Laboratories International S.R.L. Chronotherapeutic diltiazem formulations and the administration thereof
US6635277B2 (en) 2000-04-12 2003-10-21 Wockhardt Limited Composition for pulsatile delivery of diltiazem and process of manufacture
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IL136899A0 (en) * 2000-06-20 2001-06-14 Caretec Ltd Microcapsules containing arginine and the different uses thereof
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US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
US6592901B2 (en) * 2001-10-15 2003-07-15 Hercules Incorporated Highly compressible ethylcellulose for tableting
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Also Published As

Publication number Publication date
HU201684B (en) 1990-12-28
JPH01500998A (ja) 1989-04-06
HUT49815A (en) 1989-11-28
IT1200217B (it) 1989-01-05
CN1062444C (zh) 2001-02-28
DK246388D0 (da) 1988-05-06
DK174949B1 (da) 2004-03-22
PT85819B (pt) 1990-08-31
DE3786316T2 (de) 1993-10-28
CN87107792A (zh) 1988-06-29
EP0263083B1 (en) 1993-06-23
AU8025987A (en) 1988-04-21
US5149542A (en) 1992-09-22
NZ221987A (en) 1990-07-26
DK246388A (da) 1988-05-26
IT8603530A0 (it) 1986-09-30
EP0263083A1 (en) 1988-04-06
ATE90871T1 (de) 1993-07-15
PT85819A (en) 1987-10-01
KR880701542A (ko) 1988-11-03
AU602931B2 (en) 1990-11-01
DE3786316D1 (de) 1993-07-29
CA1313132C (en) 1993-01-26
FI882524A (fi) 1988-05-27
ZA877316B (en) 1988-06-29
JP2518882B2 (ja) 1996-07-31
WO1988002253A1 (en) 1988-04-07
FI882524A0 (fi) 1988-05-27

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