ES2054729T3 - Derivados de pirrolidina. - Google Patents
Derivados de pirrolidina.Info
- Publication number
- ES2054729T3 ES2054729T3 ES88106637T ES88106637T ES2054729T3 ES 2054729 T3 ES2054729 T3 ES 2054729T3 ES 88106637 T ES88106637 T ES 88106637T ES 88106637 T ES88106637 T ES 88106637T ES 2054729 T3 ES2054729 T3 ES 2054729T3
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- formula
- carboxy
- short chain
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical class C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002131 composite material Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB878710352A GB8710352D0 (en) | 1987-05-01 | 1987-05-01 | Pyrrolidine derivatives |
| GB878716438A GB8716438D0 (en) | 1987-07-13 | 1987-07-13 | Pyrrolidine derivatives |
| GB878730027A GB8730027D0 (en) | 1987-12-23 | 1987-12-23 | Pyrrolidine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2054729T3 true ES2054729T3 (es) | 1994-08-16 |
Family
ID=27263412
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES88106637T Expired - Lifetime ES2054729T3 (es) | 1987-05-01 | 1988-04-26 | Derivados de pirrolidina. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4916152A (enExample) |
| EP (1) | EP0289911B1 (enExample) |
| JP (1) | JPS63295553A (enExample) |
| KR (1) | KR970005190B1 (enExample) |
| CN (1) | CN1020899C (enExample) |
| AR (1) | AR247879A1 (enExample) |
| AU (1) | AU613360B2 (enExample) |
| CA (1) | CA1329391C (enExample) |
| DE (1) | DE3881755T2 (enExample) |
| DK (1) | DK233888A (enExample) |
| ES (1) | ES2054729T3 (enExample) |
| FI (1) | FI88716C (enExample) |
| HU (1) | HU208671B (enExample) |
| IE (1) | IE62862B1 (enExample) |
| IL (1) | IL86173A (enExample) |
| NO (1) | NO173330C (enExample) |
| PH (1) | PH24950A (enExample) |
| PT (1) | PT87359B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5130323A (en) * | 1988-10-31 | 1992-07-14 | Fujisawa Pharmaceutical Co., Ltd. | Pyrrolidine derivatives |
| US5264453A (en) * | 1988-10-31 | 1993-11-23 | Fujisawa Pharmaceutical Co., Ltd. | Pyrrolidine derivatives |
| FR2685325B1 (fr) * | 1991-12-20 | 1994-02-04 | Adir Cie | Nouveaux derives de pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| FR2687146B1 (fr) * | 1992-02-12 | 1994-04-01 | Adir Cie | Nouveaux derives de pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| RU94046180A (ru) * | 1992-07-02 | 1996-10-27 | Фудзисава Фармасьютикал Ко. | Способ получения производного пирролидина и его соли, исходный продукт и способ его получения |
| KR100671658B1 (ko) | 2005-01-05 | 2007-01-19 | 삼성에스디아이 주식회사 | 마스크 프레임 및 이를 사용한 마스크 고정방법 |
| AU2008340355B2 (en) * | 2007-12-04 | 2015-01-22 | Tekmira Pharmaceuticals Corporation | Targeting lipids |
| CN109912487B (zh) * | 2019-03-25 | 2023-01-10 | 山东理工大学 | 一种合成1-对甲苯磺酰基-2-乙烯基-1氢-吡咯的方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3577440A (en) * | 1968-12-23 | 1971-05-04 | Robins Co Inc A H | 1-substituted-3-amido-pyrrolidines |
| US4282243A (en) * | 1972-04-03 | 1981-08-04 | A. H. Robins Company, Inc. | Optical isomers of 4-amino-N-(1-cyclohexyl-3-pyrrolidinyl)-N-methylbenzamide |
| US4210660A (en) * | 1978-12-20 | 1980-07-01 | Yamanouchi Pharmaceutical Co., Ltd. | Benzamide derivatives |
| DE3165669D1 (en) * | 1980-06-23 | 1984-09-27 | Squibb & Sons Inc | Azido, imido, amido and amino derivatives of mercaptoacyl prolines and pipecolic acids having hypotensive activity |
| GB8509703D0 (en) * | 1985-04-16 | 1985-05-22 | Fujisawa Pharmaceutical Co | Pyrrolidine derivatives |
| US4785119A (en) * | 1985-10-11 | 1988-11-15 | Tokyo Kasei Kogyo Co., Ltd. | 3-aminopyrrolidine compound and process for preparation thereof |
| JPH07108898B2 (ja) * | 1986-08-20 | 1995-11-22 | 大日本製薬株式会社 | ３−アミノピロリジン誘導体およびその塩の製造法 |
| US5130323A (en) * | 1988-10-31 | 1992-07-14 | Fujisawa Pharmaceutical Co., Ltd. | Pyrrolidine derivatives |
-
1988
- 1988-04-26 PH PH36844A patent/PH24950A/en unknown
- 1988-04-26 EP EP88106637A patent/EP0289911B1/en not_active Expired - Lifetime
- 1988-04-26 ES ES88106637T patent/ES2054729T3/es not_active Expired - Lifetime
- 1988-04-26 JP JP63107305A patent/JPS63295553A/ja active Granted
- 1988-04-26 DE DE88106637T patent/DE3881755T2/de not_active Expired - Fee Related
- 1988-04-26 IL IL86173A patent/IL86173A/xx not_active IP Right Cessation
- 1988-04-27 IE IE126088A patent/IE62862B1/en not_active IP Right Cessation
- 1988-04-28 US US07/187,240 patent/US4916152A/en not_active Expired - Fee Related
- 1988-04-28 DK DK233888A patent/DK233888A/da not_active Application Discontinuation
- 1988-04-29 CA CA000565552A patent/CA1329391C/en not_active Expired - Fee Related
- 1988-04-29 NO NO881884A patent/NO173330C/no unknown
- 1988-04-29 AU AU15348/88A patent/AU613360B2/en not_active Ceased
- 1988-04-29 PT PT87359A patent/PT87359B/pt not_active IP Right Cessation
- 1988-04-29 HU HU882232A patent/HU208671B/hu not_active IP Right Cessation
- 1988-04-29 AR AR88310720A patent/AR247879A1/es active
- 1988-04-29 FI FI882015A patent/FI88716C/fi not_active IP Right Cessation
- 1988-04-30 KR KR1019880005091A patent/KR970005190B1/ko not_active Expired - Fee Related
- 1988-04-30 CN CN88102511A patent/CN1020899C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE3881755T2 (de) | 1993-10-21 |
| CA1329391C (en) | 1994-05-10 |
| FI88716B (fi) | 1993-03-15 |
| AU1534888A (en) | 1988-11-03 |
| CN88102511A (zh) | 1988-11-23 |
| IL86173A0 (en) | 1988-11-15 |
| HUT48579A (en) | 1989-06-28 |
| DK233888A (da) | 1988-11-02 |
| EP0289911B1 (en) | 1993-06-16 |
| EP0289911A3 (en) | 1989-08-16 |
| HU208671B (en) | 1993-12-28 |
| NO881884D0 (no) | 1988-04-29 |
| FI882015A0 (fi) | 1988-04-29 |
| PT87359B (pt) | 1992-08-31 |
| IL86173A (en) | 1992-02-16 |
| NO173330B (no) | 1993-08-23 |
| AU613360B2 (en) | 1991-08-01 |
| KR880013889A (ko) | 1988-12-22 |
| CN1020899C (zh) | 1993-05-26 |
| IE62862B1 (en) | 1995-03-08 |
| AR247879A1 (es) | 1995-04-28 |
| IE881260L (en) | 1988-11-01 |
| FI882015L (fi) | 1988-11-02 |
| NO173330C (no) | 1993-12-01 |
| KR970005190B1 (ko) | 1997-04-14 |
| DK233888D0 (da) | 1988-04-28 |
| FI88716C (fi) | 1993-06-28 |
| PH24950A (en) | 1990-12-26 |
| NO881884L (no) | 1988-11-02 |
| PT87359A (pt) | 1989-05-31 |
| US4916152A (en) | 1990-04-10 |
| JPS63295553A (ja) | 1988-12-01 |
| DE3881755D1 (de) | 1993-07-22 |
| JPH0546335B2 (enExample) | 1993-07-13 |
| EP0289911A2 (en) | 1988-11-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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