ES2054257T3 - Derivados de calcona. - Google Patents
Derivados de calcona.Info
- Publication number
- ES2054257T3 ES2054257T3 ES90308738T ES90308738T ES2054257T3 ES 2054257 T3 ES2054257 T3 ES 2054257T3 ES 90308738 T ES90308738 T ES 90308738T ES 90308738 T ES90308738 T ES 90308738T ES 2054257 T3 ES2054257 T3 ES 2054257T3
- Authority
- ES
- Spain
- Prior art keywords
- derivatives
- calcona
- group
- straight
- effect
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000000694 effects Effects 0.000 abstract 2
- YZCKVEUIGOORGS-UHFFFAOYSA-N Hydrogen atom Chemical compound [H] YZCKVEUIGOORGS-UHFFFAOYSA-N 0.000 abstract 1
- 230000000767 anti-ulcer Effects 0.000 abstract 1
- 210000001156 gastric mucosa Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/708—Ethers
- C07C69/712—Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
- C07C45/513—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an etherified hydroxyl group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
- C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
DICHOS DERIVADOS TIENEN LA FORMULA (I), EN LA QUE R1 ES UN GRUPO ALQUILO C4-15 CICLICO O RAMIFICADO, RECTO, O UN GRUPO ALQUENILO C3-15 Y ESTA PRESENTE EN LA POSICION 2 UADRADO) ES UN ATOMO DE HIDROGENO O UN GRUPO ALQUILENO C1-C3 RAMIFICADO O RECTO. ESTOS COMPONENTES TIENEN UN EFECTO ANTIULCERA EN LA MUCOSA GASTRICA Y UN EFECTO ANTISECRECION.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP20500589 | 1989-08-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2054257T3 true ES2054257T3 (es) | 1994-08-01 |
Family
ID=16499876
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90308738T Expired - Lifetime ES2054257T3 (es) | 1989-08-08 | 1990-08-08 | Derivados de calcona. |
Country Status (9)
Country | Link |
---|---|
US (1) | US5089654A (es) |
EP (1) | EP0412803B1 (es) |
JP (1) | JPH07119188B2 (es) |
KR (1) | KR910004525A (es) |
AT (1) | ATE103266T1 (es) |
CA (1) | CA2022812A1 (es) |
DE (1) | DE69007572T2 (es) |
DK (1) | DK0412803T3 (es) |
ES (1) | ES2054257T3 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5177259A (en) * | 1986-04-11 | 1993-01-05 | Warner-Lambert Company | Diarylalkanoids having activity as lipoxygenase inhibitors |
WO1993006075A1 (en) * | 1991-09-21 | 1993-04-01 | Taisho Pharmaceutical Co., Ltd. | Complex of compound having chalcone skeleton |
US6423740B1 (en) * | 1997-06-19 | 2002-07-23 | Indena S.P.A. | Chalcones having antiproliferative activity |
US7326734B2 (en) * | 2003-04-01 | 2008-02-05 | The Regents Of The University Of California | Treatment of bladder and urinary tract cancers |
JP3958748B2 (ja) * | 2004-02-20 | 2007-08-15 | 株式会社日本生物科学研究所 | 抗菌剤 |
CN101434533B (zh) * | 2008-12-02 | 2011-11-16 | 天津药物研究院 | 一种新型的索法酮制备方法 |
EA024343B1 (ru) * | 2010-05-17 | 2016-09-30 | Женфит | Усовершенствованный способ получения производных халкона |
CN115368265B (zh) * | 2022-10-24 | 2023-03-28 | 中国中医科学院中药研究所 | 一种索法酮小分子活性探针及其制备方法和应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5114578A (ja) * | 1974-07-29 | 1976-02-05 | Hitachi Ltd | Baransushuseiringu |
JPS5297950A (en) * | 1976-02-13 | 1977-08-17 | Taisho Pharmaceut Co Ltd | Chalconeether derivatives |
JPS5911662B2 (ja) * | 1979-12-14 | 1984-03-16 | 新日本製鐵株式会社 | ストリツプの振動防止方法 |
JPS57203585A (en) * | 1981-06-11 | 1982-12-13 | Amano Corp | Typing color switching controller for time recorder |
GB8426424D0 (en) * | 1984-10-19 | 1984-11-28 | Biorex Laboratories Ltd | Chalcone derivatives |
-
1990
- 1990-08-03 US US07/562,602 patent/US5089654A/en not_active Expired - Fee Related
- 1990-08-07 JP JP2208434A patent/JPH07119188B2/ja not_active Expired - Lifetime
- 1990-08-07 CA CA002022812A patent/CA2022812A1/en not_active Abandoned
- 1990-08-07 KR KR1019900012049A patent/KR910004525A/ko not_active Application Discontinuation
- 1990-08-08 AT AT90308738T patent/ATE103266T1/de not_active IP Right Cessation
- 1990-08-08 EP EP90308738A patent/EP0412803B1/en not_active Expired - Lifetime
- 1990-08-08 ES ES90308738T patent/ES2054257T3/es not_active Expired - Lifetime
- 1990-08-08 DE DE69007572T patent/DE69007572T2/de not_active Expired - Fee Related
- 1990-08-08 DK DK90308738.5T patent/DK0412803T3/da active
Also Published As
Publication number | Publication date |
---|---|
EP0412803A1 (en) | 1991-02-13 |
JPH03163042A (ja) | 1991-07-15 |
ATE103266T1 (de) | 1994-04-15 |
KR910004525A (ko) | 1991-03-28 |
US5089654A (en) | 1992-02-18 |
EP0412803B1 (en) | 1994-03-23 |
DE69007572D1 (de) | 1994-04-28 |
CA2022812A1 (en) | 1991-02-09 |
DK0412803T3 (da) | 1994-04-11 |
DE69007572T2 (de) | 1994-06-30 |
JPH07119188B2 (ja) | 1995-12-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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