ATE103266T1 - Chalkonderivate. - Google Patents

Chalkonderivate.

Info

Publication number
ATE103266T1
ATE103266T1 AT90308738T AT90308738T ATE103266T1 AT E103266 T1 ATE103266 T1 AT E103266T1 AT 90308738 T AT90308738 T AT 90308738T AT 90308738 T AT90308738 T AT 90308738T AT E103266 T1 ATE103266 T1 AT E103266T1
Authority
AT
Austria
Prior art keywords
conderivates
chal
effect
branched
straight
Prior art date
Application number
AT90308738T
Other languages
English (en)
Inventor
Sadakazu Yokomori
Keiko Saijo
Tohru Matsunaga
Yoshimoto Nakashima
Katsuo Hatayama
Original Assignee
Taisho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taisho Pharmaceutical Co Ltd filed Critical Taisho Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE103266T1 publication Critical patent/ATE103266T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/708—Ethers
    • C07C69/712—Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/513—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an etherified hydroxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT90308738T 1989-08-08 1990-08-08 Chalkonderivate. ATE103266T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP20500589 1989-08-08
EP90308738A EP0412803B1 (de) 1989-08-08 1990-08-08 Chalkonderivate

Publications (1)

Publication Number Publication Date
ATE103266T1 true ATE103266T1 (de) 1994-04-15

Family

ID=16499876

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90308738T ATE103266T1 (de) 1989-08-08 1990-08-08 Chalkonderivate.

Country Status (9)

Country Link
US (1) US5089654A (de)
EP (1) EP0412803B1 (de)
JP (1) JPH07119188B2 (de)
KR (1) KR910004525A (de)
AT (1) ATE103266T1 (de)
CA (1) CA2022812A1 (de)
DE (1) DE69007572T2 (de)
DK (1) DK0412803T3 (de)
ES (1) ES2054257T3 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5177259A (en) * 1986-04-11 1993-01-05 Warner-Lambert Company Diarylalkanoids having activity as lipoxygenase inhibitors
CA2119578A1 (en) * 1991-09-21 1993-04-01 Shusei Ito Complex of compound having chalcone skeleton
US6423740B1 (en) * 1997-06-19 2002-07-23 Indena S.P.A. Chalcones having antiproliferative activity
US7326734B2 (en) * 2003-04-01 2008-02-05 The Regents Of The University Of California Treatment of bladder and urinary tract cancers
JP3958748B2 (ja) * 2004-02-20 2007-08-15 株式会社日本生物科学研究所 抗菌剤
CN103025703B (zh) * 2010-05-17 2015-10-14 金菲特公司 查耳酮衍生物的改进制备
CN115368265B (zh) * 2022-10-24 2023-03-28 中国中医科学院中药研究所 一种索法酮小分子活性探针及其制备方法和应用
JP2026001671A (ja) * 2024-06-19 2026-01-07 高雄醫學大學 ソファルコン誘導体及びその医薬使用方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5114578A (ja) * 1974-07-29 1976-02-05 Hitachi Ltd Baransushuseiringu
JPS5297950A (en) * 1976-02-13 1977-08-17 Taisho Pharmaceut Co Ltd Chalconeether derivatives
JPS5911662B2 (ja) * 1979-12-14 1984-03-16 新日本製鐵株式会社 ストリツプの振動防止方法
JPS57203585A (en) * 1981-06-11 1982-12-13 Amano Corp Typing color switching controller for time recorder
GB8426424D0 (en) * 1984-10-19 1984-11-28 Biorex Laboratories Ltd Chalcone derivatives

Also Published As

Publication number Publication date
JPH03163042A (ja) 1991-07-15
US5089654A (en) 1992-02-18
EP0412803A1 (de) 1991-02-13
DK0412803T3 (da) 1994-04-11
JPH07119188B2 (ja) 1995-12-20
KR910004525A (ko) 1991-03-28
CA2022812A1 (en) 1991-02-09
DE69007572D1 (de) 1994-04-28
EP0412803B1 (de) 1994-03-23
DE69007572T2 (de) 1994-06-30
ES2054257T3 (es) 1994-08-01

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee