KR910004525A - 칼콘 유도체 - Google Patents
칼콘 유도체 Download PDFInfo
- Publication number
- KR910004525A KR910004525A KR1019900012049A KR900012049A KR910004525A KR 910004525 A KR910004525 A KR 910004525A KR 1019900012049 A KR1019900012049 A KR 1019900012049A KR 900012049 A KR900012049 A KR 900012049A KR 910004525 A KR910004525 A KR 910004525A
- Authority
- KR
- South Korea
- Prior art keywords
- carbon atoms
- chalcone
- alkyl group
- straight
- branched
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/708—Ethers
- C07C69/712—Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
- C07C45/513—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an etherified hydroxyl group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
- C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
내용 없음.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (9)
- 다음 식으로 표시되는 칼콘 유도체.상기식에서, R1은 4내지 15개의 탄소 원자를 갖는 직쇄, 분지쇄 또는 시클릭 알킬기 또는 3 내지 15개의 탄소 원자를 갖는 알케닐기로서, 2 또는 4 위치에 결합되고, R2는 수소 원자 또는 1 내지 3개의 탄소 원자를 갖는 직쇄 또는 분지쇄 알킬기이고, X는 1 내지 3개의 탄소 원자를 갖는 직쇄 분지쇄 알킬렌기이다.
- 제1항에 있어서, R1이 5 내지 8개의 탄소 원자를 갖는 직쇄 알킬기, 4 내지 7개의 탄소 원자를 갖는 분지쇄 알킬기 또는 4 내지 8개의 탄소 원자를 갖는 알케닐기이고, R2가 수소 원자 또는 1 내지 3개의 탄소 원자를 갖는 직쇄 또는 분지쇄 알킬기이고, X가 메틸렌기인 것이 특징인 칼콘 유도체.
- 제1항에 있어서, R1이 6 또는 7개의 탄소 원자를 갖는 직쇄 알킬기, 4개의 탄소 원자를 갖는 분지쇄 알킬기 또는 6 내지 7개의 탄소 원자를 갖는 1-알케닐기로서, 4 위치에 결합되고, R2가 수소 원자이고, X가 메틸렌기인 것이 특징인 칼콘 유도체.
- 다음 식으로 표시되는 칼콘 유도체.상기 식에서, R1은 4 내지 15개의 탄소 원자를 갖는 직쇄, 분자쇄 또는 시클릭 알킬기 또는 3 내지 15개의 탄소 원자를 갖는 알케닐기로서 2 또는 4 위치에 결합된다.
- 2′-카르복시메톡시-4-헥실-4′-(3-메틸-2-부테닐옥시)칼콘.
- 2′-카르복시메톡시-4-헵틸-4′-(3-메틸-2-부테닐옥시)칼콘.
- 2′-카르복시메톡시-4-(1-(E)-헵테닐)-4′-(3-메틸-2-부테닐옥시)칼콘.
- 2′-카르복시메톡시-4-(1-(E)-헥세닐)-4′-(3-메틸-2-부테닐옥시)칼콘.
- 4-t-부틸-2′-카르복시메톡시-4′-(3-메틸-2-부테닐옥시)칼콘.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1-205005 | 1989-08-08 | ||
JP20500589 | 1989-08-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
KR910004525A true KR910004525A (ko) | 1991-03-28 |
Family
ID=16499876
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019900012049A KR910004525A (ko) | 1989-08-08 | 1990-08-07 | 칼콘 유도체 |
Country Status (9)
Country | Link |
---|---|
US (1) | US5089654A (ko) |
EP (1) | EP0412803B1 (ko) |
JP (1) | JPH07119188B2 (ko) |
KR (1) | KR910004525A (ko) |
AT (1) | ATE103266T1 (ko) |
CA (1) | CA2022812A1 (ko) |
DE (1) | DE69007572T2 (ko) |
DK (1) | DK0412803T3 (ko) |
ES (1) | ES2054257T3 (ko) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5177259A (en) * | 1986-04-11 | 1993-01-05 | Warner-Lambert Company | Diarylalkanoids having activity as lipoxygenase inhibitors |
CA2119578A1 (en) * | 1991-09-21 | 1993-04-01 | Shusei Ito | Complex of compound having chalcone skeleton |
US6423740B1 (en) * | 1997-06-19 | 2002-07-23 | Indena S.P.A. | Chalcones having antiproliferative activity |
US7326734B2 (en) * | 2003-04-01 | 2008-02-05 | The Regents Of The University Of California | Treatment of bladder and urinary tract cancers |
JP3958748B2 (ja) * | 2004-02-20 | 2007-08-15 | 株式会社日本生物科学研究所 | 抗菌剤 |
CN101434533B (zh) * | 2008-12-02 | 2011-11-16 | 天津药物研究院 | 一种新型的索法酮制备方法 |
NO2571843T3 (ko) * | 2010-05-17 | 2018-05-26 | ||
CN115368265B (zh) * | 2022-10-24 | 2023-03-28 | 中国中医科学院中药研究所 | 一种索法酮小分子活性探针及其制备方法和应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5114578A (ja) * | 1974-07-29 | 1976-02-05 | Hitachi Ltd | Baransushuseiringu |
JPS5297950A (en) * | 1976-02-13 | 1977-08-17 | Taisho Pharmaceut Co Ltd | Chalconeether derivatives |
JPS5911662B2 (ja) * | 1979-12-14 | 1984-03-16 | 新日本製鐵株式会社 | ストリツプの振動防止方法 |
JPS57203585A (en) * | 1981-06-11 | 1982-12-13 | Amano Corp | Typing color switching controller for time recorder |
GB8426424D0 (en) * | 1984-10-19 | 1984-11-28 | Biorex Laboratories Ltd | Chalcone derivatives |
-
1990
- 1990-08-03 US US07/562,602 patent/US5089654A/en not_active Expired - Fee Related
- 1990-08-07 CA CA002022812A patent/CA2022812A1/en not_active Abandoned
- 1990-08-07 JP JP2208434A patent/JPH07119188B2/ja not_active Expired - Lifetime
- 1990-08-07 KR KR1019900012049A patent/KR910004525A/ko not_active Application Discontinuation
- 1990-08-08 ES ES90308738T patent/ES2054257T3/es not_active Expired - Lifetime
- 1990-08-08 DK DK90308738.5T patent/DK0412803T3/da active
- 1990-08-08 AT AT90308738T patent/ATE103266T1/de not_active IP Right Cessation
- 1990-08-08 EP EP90308738A patent/EP0412803B1/en not_active Expired - Lifetime
- 1990-08-08 DE DE69007572T patent/DE69007572T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5089654A (en) | 1992-02-18 |
JPH03163042A (ja) | 1991-07-15 |
DE69007572D1 (de) | 1994-04-28 |
ES2054257T3 (es) | 1994-08-01 |
JPH07119188B2 (ja) | 1995-12-20 |
EP0412803B1 (en) | 1994-03-23 |
EP0412803A1 (en) | 1991-02-13 |
CA2022812A1 (en) | 1991-02-09 |
DK0412803T3 (da) | 1994-04-11 |
ATE103266T1 (de) | 1994-04-15 |
DE69007572T2 (de) | 1994-06-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |