ES2053586T3 - Vectores para la clonacion y expresividad de genes heterologos en levaduras asi como variedades de levaduras transformadas por dichos vectores. - Google Patents

Vectores para la clonacion y expresividad de genes heterologos en levaduras asi como variedades de levaduras transformadas por dichos vectores.

Info

Publication number
ES2053586T3
ES2053586T3 ES87830114T ES87830114T ES2053586T3 ES 2053586 T3 ES2053586 T3 ES 2053586T3 ES 87830114 T ES87830114 T ES 87830114T ES 87830114 T ES87830114 T ES 87830114T ES 2053586 T3 ES2053586 T3 ES 2053586T3
Authority
ES
Spain
Prior art keywords
vectors
yeast
cloning
heterological
expressivity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87830114T
Other languages
English (en)
Inventor
Falcone Claudio
Fukuhara Hiroshi
Frontali Laura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Consiglio Nazionale delle Richerche CNR
Universita degli Studi di Roma La Sapienza
Original Assignee
Centre National de la Recherche Scientifique CNRS
Consiglio Nazionale delle Richerche CNR
Universita degli Studi di Roma La Sapienza
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Consiglio Nazionale delle Richerche CNR, Universita degli Studi di Roma La Sapienza filed Critical Centre National de la Recherche Scientifique CNRS
Application granted granted Critical
Publication of ES2053586T3 publication Critical patent/ES2053586T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A VECTORES PARA LA CLONACION Y EXPRESION DE GENES HETEROLOGOS EN LEVADURA, SIENDO CARACTERISTICO DE DICHOS VECTORES EL HECHO DE QUE CONTIENEN AL MENOS EL ADN COMPLETO DEL PLASMIDO PKD1 (AISLADO DE KLUYVEROMYCES DROSOPHILARUM) O PARTE DE EL, ASI COMO UN SEGMENTO DE ADN QUE LLEVA UN GEN HETEROLOGO Y LA SECUENCIA NECESARIA PARA LA EXPRESION DE DICHO GEN. LA ALTA ESTABILIDAD DE LAS LEVADURAS TRANSFORMADAS POR DICHOS VECTORES, PERMITE SU UTILIZACION A ESCALA INDUSTRIAL EN VARIOS CAMPOS BIOTECNOLOGICOS.
ES87830114T 1986-03-27 1987-03-25 Vectores para la clonacion y expresividad de genes heterologos en levaduras asi como variedades de levaduras transformadas por dichos vectores. Expired - Lifetime ES2053586T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT47830/86A IT1203758B (it) 1986-03-27 1986-03-27 Vettori di clonazione e di espressione di geni eterologhi in lieviti e lieviti trasformati con tali vettori

Publications (1)

Publication Number Publication Date
ES2053586T3 true ES2053586T3 (es) 1994-08-01

Family

ID=11262795

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87830114T Expired - Lifetime ES2053586T3 (es) 1986-03-27 1987-03-25 Vectores para la clonacion y expresividad de genes heterologos en levaduras asi como variedades de levaduras transformadas por dichos vectores.

Country Status (7)

Country Link
EP (1) EP0241435B1 (es)
JP (1) JP2646085B2 (es)
AT (1) ATE83009T1 (es)
DE (2) DE3782844T2 (es)
ES (1) ES2053586T3 (es)
GR (1) GR3007153T3 (es)
IT (1) IT1203758B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4943529A (en) 1982-05-19 1990-07-24 Gist-Brocades Nv Kluyveromyces as a host strain
IL87258A (en) * 1987-07-28 1994-02-27 Gist Brocades Nv SECYMOREVYULK surrogate cells and their use for the expression of polypeptides
FR2649991B2 (fr) * 1988-08-05 1994-03-04 Rhone Poulenc Sante Utilisation de derives stables du plasmide pkd1 pour l'expression et la secretion de proteines heterologues dans les levures du genre kluyveromyces
JPH0486191A (ja) * 1990-07-30 1992-03-18 Aiphone Co Ltd テレビドアホン方式
FR2678636A1 (fr) * 1991-07-02 1993-01-08 Rhone Poulenc Rorer Sa Procede de production de proteines recombinantes et cellules hote utilisees.
FR2686899B1 (fr) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
DE4226971C2 (de) * 1992-08-14 1997-01-16 Widmar Prof Dr Tanner Modifizierte Pilzzellen und Verfahren zur Herstellung rekombinanter Produkte
GB9526733D0 (en) 1995-12-30 1996-02-28 Delta Biotechnology Ltd Fusion proteins
US6358705B1 (en) 1998-07-16 2002-03-19 Novo Nordisk A/S Method of making proteins in transformed yeast cells
US6946134B1 (en) 2000-04-12 2005-09-20 Human Genome Sciences, Inc. Albumin fusion proteins
US20030171267A1 (en) 2000-04-12 2003-09-11 Rosen Craig A. Albumin fusion proteins
EP2305312B1 (en) 2001-10-10 2015-03-04 ratiopharm GmbH Remodelling and glycoconjugation of follicle-stimulating hormone (FSH)
ES2561985T3 (es) 2001-10-10 2016-03-01 Ratiopharm Gmbh Remodelación y glicoconjugación de anticuerpos
EP1997829A1 (en) 2001-12-21 2008-12-03 Human Genome Sciences, Inc. Albumin fusion proteins
AU2002364587A1 (en) 2001-12-21 2003-07-30 Human Genome Sciences, Inc. Albumin fusion proteins
EP2338333B1 (en) 2003-04-09 2017-09-06 ratiopharm GmbH Glycopegylation methods and proteins/peptides produced by the methods

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0096910B1 (en) * 1982-05-19 1989-04-19 Unilever N.V. Yeast of the genus kluyveromyces modified for the expression of preprothaumatin or its various allelic and modified forms or their maturation forms
FR2532656B2 (fr) * 1982-06-02 1985-10-18 Elf Bio Rech Nouveau vecteur de clonage et d'expression, levure et bacterie transformees par ce vecteur

Also Published As

Publication number Publication date
JP2646085B2 (ja) 1997-08-25
EP0241435A3 (en) 1988-09-14
EP0241435B1 (en) 1992-12-02
GR3007153T3 (es) 1993-07-30
DE3782844D1 (de) 1993-01-14
DE3782844T2 (de) 1993-06-17
IT1203758B (it) 1989-02-23
EP0241435A2 (en) 1987-10-14
DE241435T1 (de) 1989-03-09
JPS63290A (ja) 1988-01-05
IT8647830A0 (it) 1986-03-27
ATE83009T1 (de) 1992-12-15

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