ES2046083B1 - Procedimiento para preparar composiciones de liberacion prolongada. - Google Patents

Procedimiento para preparar composiciones de liberacion prolongada.

Info

Publication number
ES2046083B1
ES2046083B1 ES09101785A ES9101785A ES2046083B1 ES 2046083 B1 ES2046083 B1 ES 2046083B1 ES 09101785 A ES09101785 A ES 09101785A ES 9101785 A ES9101785 A ES 9101785A ES 2046083 B1 ES2046083 B1 ES 2046083B1
Authority
ES
Spain
Prior art keywords
procedure
prolonged release
release compositions
preparing
active ingredients
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES09101785A
Other languages
English (en)
Spanish (es)
Other versions
ES2046083A1 (es
Inventor
Jean-Marc Ruiz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Publication of ES2046083A1 publication Critical patent/ES2046083A1/es
Application granted granted Critical
Publication of ES2046083B1 publication Critical patent/ES2046083B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Glanulating (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES09101785A 1990-08-01 1991-07-30 Procedimiento para preparar composiciones de liberacion prolongada. Expired - Fee Related ES2046083B1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909016885A GB9016885D0 (en) 1990-08-01 1990-08-01 Sustained release pharmaceutical compositions

Publications (2)

Publication Number Publication Date
ES2046083A1 ES2046083A1 (es) 1994-01-16
ES2046083B1 true ES2046083B1 (es) 1994-08-01

Family

ID=10679993

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09101785A Expired - Fee Related ES2046083B1 (es) 1990-08-01 1991-07-30 Procedimiento para preparar composiciones de liberacion prolongada.

Country Status (30)

Country Link
US (1) US5213812A (enExample)
JP (1) JP2818704B2 (enExample)
KR (1) KR920003962A (enExample)
AT (1) AT396425B (enExample)
AU (2) AU649696B2 (enExample)
BE (1) BE1004772A3 (enExample)
CA (1) CA2048270C (enExample)
CH (1) CH682715A5 (enExample)
DE (1) DE4125542A1 (enExample)
DK (1) DK175756B1 (enExample)
ES (1) ES2046083B1 (enExample)
FI (1) FI104149B (enExample)
FR (1) FR2665360B1 (enExample)
GB (1) GB9016885D0 (enExample)
GR (1) GR1001512B (enExample)
HK (1) HK33294A (enExample)
IE (1) IE65124B1 (enExample)
IN (1) IN178446B (enExample)
IT (1) IT1251788B (enExample)
LU (1) LU87982A1 (enExample)
MA (1) MA22245A1 (enExample)
MY (1) MY107500A (enExample)
NL (1) NL194637C (enExample)
NO (1) NO300158B1 (enExample)
NZ (1) NZ238981A (enExample)
OA (1) OA09387A (enExample)
PT (1) PT98497B (enExample)
SE (1) SE505734C2 (enExample)
TN (1) TNSN91067A1 (enExample)
ZA (1) ZA915565B (enExample)

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GB9310030D0 (en) * 1993-05-15 1993-06-30 Scras Dry processed particles and process for the preparation of the same
ES2188652T3 (es) * 1994-02-28 2003-07-01 Nanopharm Ag Sistema de direccionado de farmacos, metodos de fabricacion y uso del mismo.
US5980945A (en) * 1996-01-16 1999-11-09 Societe De Conseils De Recherches Et D'applications Scientifique S.A. Sustained release drug formulations
DE19604744A1 (de) 1996-02-09 1997-08-14 Henkel Kgaa Technische Di-/Triglyceridgemische
DE19617137C1 (de) * 1996-04-29 1997-02-27 Henkel Kgaa Verwendung von Copolymerestern für die Herstellung von Mikrosphären
WO1998015263A2 (en) * 1996-10-09 1998-04-16 Takeda Chemical Industries, Ltd. A method for producing a microparticle
AR012448A1 (es) * 1997-04-18 2000-10-18 Ipsen Pharma Biotech Composicion en forma de microcapsulas o de implantes que comprende un excipiente biodegradable, polimero o co-polimero, o una mezcla de talesexcipientes, y una sustancia activa o una mezcla de sustancias activas, procedimiento para la preparacion de una sustancia soluble en agua de elevada
EP1079967A4 (en) 1998-04-13 2003-07-23 Luminex Corp LIQUID MARKING USING FLUORESCENT MICROPARTICLES
OA11728A (en) * 1998-12-16 2005-02-01 Aventis Pharma Inc Biodegradable polymer encapsulated serotonin receptor antagonist and method for preparing the same.
AU5644400A (en) * 1999-09-24 2001-03-29 Rohm And Haas Company Pellet compositions
US6458387B1 (en) * 1999-10-18 2002-10-01 Epic Therapeutics, Inc. Sustained release microspheres
ES2326209T3 (es) 2000-10-27 2009-10-05 Baxter Healthcare S.A. Produccion de microesferas.
US20080026068A1 (en) * 2001-08-16 2008-01-31 Baxter Healthcare S.A. Pulmonary delivery of spherical insulin microparticles
PT1418890E (pt) * 2001-08-16 2008-06-09 Baxter Int Formulações de micropartículas à base de propulsor
US20040166077A1 (en) * 2002-12-04 2004-08-26 L'oreal Process for treating keratin materials with aromatic active principles
FR2848113B1 (fr) * 2002-12-04 2005-02-25 Oreal Stabilisation de principes actifs aromatiques par des polymeres aromatiques
US20070092452A1 (en) * 2003-07-18 2007-04-26 Julia Rashba-Step Methods for fabrication, uses, compositions of inhalable spherical particles
AU2004280158B2 (en) * 2003-07-18 2011-02-17 Baxter International, Inc. Methods for fabrication, uses and compositions of small spherical particles prepared by controlled phase separation
US20050142205A1 (en) * 2003-07-18 2005-06-30 Julia Rashba-Step Methods for encapsulating small spherical particles prepared by controlled phase separation
CA2532874A1 (en) * 2003-07-22 2005-02-03 Baxter International Inc. Small spherical particles of low molecular weight organic molecules and methods of preparation and use thereof
US20060135277A1 (en) * 2003-09-10 2006-06-22 Marnocha Bendict F Golf club and practice arrangement
FR2865938B1 (fr) * 2004-02-05 2006-06-02 Sod Conseils Rech Applic Formulation retard solide comprenant de l'acetate de triptoreline
US8333995B2 (en) * 2004-05-12 2012-12-18 Baxter International, Inc. Protein microspheres having injectable properties at high concentrations
JP2007537284A (ja) 2004-05-12 2007-12-20 バクスター インターナショナル インコーポレイテッド 核酸マイクロスフェア、その生成および送達
EP1758558B1 (en) * 2004-05-12 2013-10-16 Baxter International Inc. Oligonucleotide-containing microspheres, their use for the manufacture of a medicament for treating diabetes type 1
US8728525B2 (en) * 2004-05-12 2014-05-20 Baxter International Inc. Protein microspheres retaining pharmacokinetic and pharmacodynamic properties
EP1773264A1 (en) * 2004-07-13 2007-04-18 Altairnano, Inc Ceramic structures for controlled release of drugs
CA2573341A1 (en) * 2004-07-13 2006-02-16 Altairnano, Inc. Ceramic structures for prevention of drug diversion
WO2006050345A1 (en) * 2004-10-29 2006-05-11 Adhesives Research, Inc. Microscopic tagging system for security identification
WO2006116546A1 (en) * 2005-04-27 2006-11-02 Baxter International Inc. Surface-modified microparticles and methods of forming and using the same
EP1928814A2 (en) * 2005-08-23 2008-06-11 Altairnano, Inc HIGHLY PHOTOCATALYTIC PHOSPHORUS-DOPED ANATASE-TiO2 COMPOSITION AND RELATED MANUFACTURING METHODS
US20080038482A1 (en) * 2006-03-02 2008-02-14 Fred Ratel Method for Low Temperature Production of Nano-Structured Iron Oxide Coatings
WO2007103820A1 (en) * 2006-03-02 2007-09-13 Altairnano, Inc. Nanostructured indium-doped iron oxide
US20080008843A1 (en) * 2006-03-02 2008-01-10 Fred Ratel Method for Production of Metal Oxide Coatings
US20070281031A1 (en) * 2006-06-01 2007-12-06 Guohan Yang Microparticles and methods for production thereof
EP2056883B1 (en) 2006-08-04 2021-09-22 Baxter International Inc. Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes
CA2663589A1 (en) * 2006-10-06 2008-05-22 Baxter International Inc. Microencapsules containing surface-modified microparticles and methods of forming and using the same
US9017697B2 (en) 2006-10-12 2015-04-28 The University Of Queensland Compositions and methods for modulating immune responses
US20090169628A1 (en) * 2006-10-17 2009-07-02 Armark Authentication Technologies, Llc Article and method for focused delivery of therapeutic and/or diagnostic materials
WO2008128000A1 (en) * 2007-04-12 2008-10-23 Altairnano, Inc. Teflon replacements and related production methods
CN101686939B (zh) * 2007-04-17 2013-03-27 巴克斯特国际公司 用于肺部投送的核酸微粒
US9782300B2 (en) 2008-02-01 2017-10-10 Kci Licensing, Inc. Fiber-microsphere bioresorbable composite scaffold for wound healing
ES2554168T3 (es) 2008-04-18 2015-12-16 Baxter International Inc. Composición basada en microesferas para prevenir y/o revertir la diabetes autoinmune de nueva aparición
US8323615B2 (en) * 2008-08-20 2012-12-04 Baxter International Inc. Methods of processing multi-phasic dispersions
US20100047292A1 (en) * 2008-08-20 2010-02-25 Baxter International Inc. Methods of processing microparticles and compositions produced thereby
US8367427B2 (en) * 2008-08-20 2013-02-05 Baxter International Inc. Methods of processing compositions containing microparticles
US8323685B2 (en) * 2008-08-20 2012-12-04 Baxter International Inc. Methods of processing compositions containing microparticles
US20100078848A1 (en) * 2008-09-29 2010-04-01 Armark Authentication Technologies, Llc Spinneret and method of spinning fiber
US20100291214A1 (en) * 2008-12-23 2010-11-18 Armark Authentication Technologies, Llc Three-dimensional microfiber extrudate structure and process for forming three-dimensional microfiber extrudate structure
US20100291384A1 (en) * 2009-05-15 2010-11-18 Armark Authentication Technologies, Llc Fiber having non-uniform composition and method for making same
CN102481374A (zh) * 2009-05-27 2012-05-30 西莱克塔生物科技公司 具有免疫调节剂的pH敏感释放的靶向合成纳米载体
US20110076771A1 (en) * 2009-09-25 2011-03-31 Armark Authentication Technologies, Llc Tissue fiber scaffold and method for making
JP6324068B2 (ja) 2010-05-26 2018-05-23 セレクタ バイオサイエンシーズ インコーポレーテッドＳｅｌｅｃｔａ Ｂｉｏｓｃｉｅｎｃｅｓ，Ｉｎｃ． 合成ナノキャリア混合ワクチン
EP2399931A1 (fr) * 2010-06-22 2011-12-28 Ipsen Pharma S.A.S. Nouveaux composés octapeptidiques et leur utilisation thérapeutique
BR112013010926A2 (pt) 2010-11-01 2016-08-23 Univ Technology Sidney agentes imunomoduladores e seus usos
CN109172819A (zh) 2011-07-29 2019-01-11 西莱克塔生物科技公司 产生体液和细胞毒性t淋巴细胞（ctl）免疫应答的合成纳米载体
EP3149049B1 (en) 2014-05-27 2022-10-26 The University Of Queensland Il-22 for use in treating metabolic disorders
FR3067226B1 (fr) * 2017-06-13 2021-10-08 Rossignol Lange Element de chaussure de ski

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IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
JPS60100516A (ja) * 1983-11-04 1985-06-04 Takeda Chem Ind Ltd 徐放型マイクロカプセルの製造法
IN167096B (enExample) * 1985-04-04 1990-09-01 Akzo Nv
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AU4369589A (en) * 1988-10-27 1990-05-03 Abbott Laboratories Controlled-release delivery device, method for producing device, and method of using device

Also Published As

Publication number Publication date
US5213812A (en) 1993-05-25
KR920003962A (ko) 1992-03-27
OA09387A (fr) 1992-09-15
AU8146691A (en) 1992-02-06
DK175756B1 (da) 2005-02-14
FR2665360B1 (fr) 1995-02-10
IE65124B1 (en) 1995-10-04
DK141891A (da) 1992-02-02
LU87982A1 (fr) 1992-04-15
GR910100330A (en) 1992-08-31
FR2665360A1 (fr) 1992-02-07
FI104149B1 (fi) 1999-11-30
ITMI911953A0 (it) 1991-07-15
FI913646A0 (fi) 1991-07-31
ES2046083A1 (es) 1994-01-16
BE1004772A3 (fr) 1993-01-26
JPH05178740A (ja) 1993-07-20
HK33294A (en) 1994-04-22
ITMI911953A1 (it) 1993-01-15
GR1001512B (el) 1994-02-28
FI104149B (fi) 1999-11-30
AU666808B2 (en) 1996-02-22
SE9102249L (sv) 1992-02-02
JP2818704B2 (ja) 1998-10-30
IE912700A1 (en) 1992-02-12
IN178446B (enExample) 1997-05-03
GB9016885D0 (en) 1990-09-12
CH682715A5 (fr) 1993-11-15
CA2048270A1 (en) 1992-02-02
TNSN91067A1 (fr) 1992-10-25
ZA915565B (en) 1992-04-29
MA22245A1 (fr) 1992-04-01
NO912986D0 (no) 1991-07-31
PT98497B (pt) 1997-10-31
NL9101306A (nl) 1992-03-02
DE4125542A1 (de) 1992-02-06
CA2048270C (en) 1997-02-25
IT1251788B (it) 1995-05-26
DK141891D0 (da) 1991-07-31
AT396425B (de) 1993-09-27
MY107500A (en) 1995-12-30
NO300158B1 (no) 1997-04-21
SE505734C2 (sv) 1997-10-06
SE9102249D0 (sv) 1991-07-26
PT98497A (pt) 1992-06-30
AU649696B2 (en) 1994-06-02
NL194637B (nl) 2002-06-03
NO912986L (no) 1992-02-03
NL194637C (nl) 2002-10-04
ATA152591A (de) 1993-01-15
FI913646L (fi) 1992-02-02
AU5939394A (en) 1994-06-02
NZ238981A (en) 1992-11-25

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Legal Events

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Effective date: 20110819