CH682715A5 - Procédé de préparation de compositions à libération prolongée et compositions ainsi obtenues. - Google Patents
Procédé de préparation de compositions à libération prolongée et compositions ainsi obtenues. Download PDFInfo
- Publication number
- CH682715A5 CH682715A5 CH2179/91A CH217991A CH682715A5 CH 682715 A5 CH682715 A5 CH 682715A5 CH 2179/91 A CH2179/91 A CH 2179/91A CH 217991 A CH217991 A CH 217991A CH 682715 A5 CH682715 A5 CH 682715A5
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- CH
- Switzerland
- Prior art keywords
- gel
- particles
- mpa
- viscosity
- phase
- Prior art date
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- XZZXIYZZBJDEEP-UHFFFAOYSA-N imipramine hydrochloride Chemical compound [Cl-].C1CC2=CC=CC=C2N(CCC[NH+](C)C)C2=CC=CC=C21 XZZXIYZZBJDEEP-UHFFFAOYSA-N 0.000 description 1
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- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
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- RWHUEXWOYVBUCI-ITQXDASVSA-N nafarelin Chemical compound C([C@@H](C(=O)N[C@H](CC=1C=C2C=CC=CC2=CC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1[C@@H](CCC1)C(=O)NCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H]1NC(=O)CC1)C1=CC=C(O)C=C1 RWHUEXWOYVBUCI-ITQXDASVSA-N 0.000 description 1
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- WEXRUCMBJFQVBZ-UHFFFAOYSA-N pentobarbital Chemical compound CCCC(C)C1(CC)C(=O)NC(=O)NC1=O WEXRUCMBJFQVBZ-UHFFFAOYSA-N 0.000 description 1
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- DDBREPKUVSBGFI-UHFFFAOYSA-N phenobarbital Chemical compound C=1C=CC=CC=1C1(CC)C(=O)NC(=O)NC1=O DDBREPKUVSBGFI-UHFFFAOYSA-N 0.000 description 1
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- 229960003147 reserpine Drugs 0.000 description 1
- MDMGHDFNKNZPAU-UHFFFAOYSA-N roserpine Natural products C1C2CN3CCC(C4=CC=C(OC)C=C4N4)=C4C3CC2C(OC(C)=O)C(OC)C1OC(=O)C1=CC(OC)=C(OC)C(OC)=C1 MDMGHDFNKNZPAU-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Biological Depolymerization Polymers (AREA)
- Glanulating (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909016885A GB9016885D0 (en) | 1990-08-01 | 1990-08-01 | Sustained release pharmaceutical compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH682715A5 true CH682715A5 (fr) | 1993-11-15 |
Family
ID=10679993
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH2179/91A CH682715A5 (fr) | 1990-08-01 | 1991-07-22 | Procédé de préparation de compositions à libération prolongée et compositions ainsi obtenues. |
Country Status (30)
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| JP (1) | JP2818704B2 (enExample) |
| KR (1) | KR920003962A (enExample) |
| AT (1) | AT396425B (enExample) |
| AU (2) | AU649696B2 (enExample) |
| BE (1) | BE1004772A3 (enExample) |
| CA (1) | CA2048270C (enExample) |
| CH (1) | CH682715A5 (enExample) |
| DE (1) | DE4125542A1 (enExample) |
| DK (1) | DK175756B1 (enExample) |
| ES (1) | ES2046083B1 (enExample) |
| FI (1) | FI104149B (enExample) |
| FR (1) | FR2665360B1 (enExample) |
| GB (1) | GB9016885D0 (enExample) |
| GR (1) | GR1001512B (enExample) |
| HK (1) | HK33294A (enExample) |
| IE (1) | IE65124B1 (enExample) |
| IN (1) | IN178446B (enExample) |
| IT (1) | IT1251788B (enExample) |
| LU (1) | LU87982A1 (enExample) |
| MA (1) | MA22245A1 (enExample) |
| MY (1) | MY107500A (enExample) |
| NL (1) | NL194637C (enExample) |
| NO (1) | NO300158B1 (enExample) |
| NZ (1) | NZ238981A (enExample) |
| OA (1) | OA09387A (enExample) |
| PT (1) | PT98497B (enExample) |
| SE (1) | SE505734C2 (enExample) |
| TN (1) | TNSN91067A1 (enExample) |
| ZA (1) | ZA915565B (enExample) |
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| GB9310030D0 (en) * | 1993-05-15 | 1993-06-30 | Scras | Dry processed particles and process for the preparation of the same |
| US5569467A (en) * | 1993-05-15 | 1996-10-29 | Societe De Conseils De Recherches Et D'applications (S.C.R.A.S.) | Process for the preparation of microballs and microballs thus obtained |
| WO1995022963A1 (en) * | 1994-02-28 | 1995-08-31 | Medinova Medical Consulting Gmbh | Drug targeting system, method for preparing same and its use |
| US5980945A (en) * | 1996-01-16 | 1999-11-09 | Societe De Conseils De Recherches Et D'applications Scientifique S.A. | Sustained release drug formulations |
| DE19604744A1 (de) | 1996-02-09 | 1997-08-14 | Henkel Kgaa | Technische Di-/Triglyceridgemische |
| DE19617137C1 (de) * | 1996-04-29 | 1997-02-27 | Henkel Kgaa | Verwendung von Copolymerestern für die Herstellung von Mikrosphären |
| AU4571097A (en) * | 1996-10-09 | 1998-05-05 | Takeda Chemical Industries Ltd. | A method for producing a microparticle |
| AR012448A1 (es) * | 1997-04-18 | 2000-10-18 | Ipsen Pharma Biotech | Composicion en forma de microcapsulas o de implantes que comprende un excipiente biodegradable, polimero o co-polimero, o una mezcla de talesexcipientes, y una sustancia activa o una mezcla de sustancias activas, procedimiento para la preparacion de una sustancia soluble en agua de elevada |
| EP1079967A4 (en) | 1998-04-13 | 2003-07-23 | Luminex Corp | LIQUID MARKING USING FLUORESCENT MICROPARTICLES |
| CZ301947B6 (cs) * | 1998-12-16 | 2010-08-11 | Aventisub Ii Inc. | Zpusob výroby farmaceutické kompozice vykazující aktivitu antagonisty serotoninového receptoru a farmaceutická kompozice vykazující uvedenou aktivitu |
| AU5644400A (en) * | 1999-09-24 | 2001-03-29 | Rohm And Haas Company | Pellet compositions |
| US6458387B1 (en) * | 1999-10-18 | 2002-10-01 | Epic Therapeutics, Inc. | Sustained release microspheres |
| DE60138641D1 (de) | 2000-10-27 | 2009-06-18 | Baxter Healthcare Sa | Herstellung von mikrokügelchen |
| WO2003015750A1 (en) * | 2001-08-16 | 2003-02-27 | Baxter International, Inc. | Propellant-based microparticle formulations |
| US20080026068A1 (en) * | 2001-08-16 | 2008-01-31 | Baxter Healthcare S.A. | Pulmonary delivery of spherical insulin microparticles |
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| US20040166077A1 (en) * | 2002-12-04 | 2004-08-26 | L'oreal | Process for treating keratin materials with aromatic active principles |
| US20050142205A1 (en) * | 2003-07-18 | 2005-06-30 | Julia Rashba-Step | Methods for encapsulating small spherical particles prepared by controlled phase separation |
| KR101137785B1 (ko) * | 2003-07-18 | 2012-04-25 | 백스터 인터내셔널 인코포레이티드 | 제어된 상 분리에 의해 제조된 작은 구형 입자의 제조방법, 이용 방법 및 조성물 |
| US20070092452A1 (en) * | 2003-07-18 | 2007-04-26 | Julia Rashba-Step | Methods for fabrication, uses, compositions of inhalable spherical particles |
| CA2532874A1 (en) * | 2003-07-22 | 2005-02-03 | Baxter International Inc. | Small spherical particles of low molecular weight organic molecules and methods of preparation and use thereof |
| US20060135277A1 (en) * | 2003-09-10 | 2006-06-22 | Marnocha Bendict F | Golf club and practice arrangement |
| FR2865938B1 (fr) * | 2004-02-05 | 2006-06-02 | Sod Conseils Rech Applic | Formulation retard solide comprenant de l'acetate de triptoreline |
| JP2007537288A (ja) * | 2004-05-12 | 2007-12-20 | バクスター インターナショナル インコーポレイテッド | オリゴヌクレオチド含有マイクロスフェア、１型糖尿病を処置する医薬の製造のための、その使用 |
| CA2566075A1 (en) * | 2004-05-12 | 2005-12-01 | Baxter Healthcare S.A. | Microspheres comprising protein and showing injectability at high concentrations of said agent |
| PT1765294E (pt) | 2004-05-12 | 2008-12-30 | Baxter Healthcare Sa | Microesferas de ácido nucleico, sua produção e entrega |
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| JP2009505824A (ja) * | 2005-08-23 | 2009-02-12 | アルテアナノ インコーポレイテッド | 高度な光触媒のリンドープアナターゼＴｉＯ２組成物及びその製造方法 |
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| IN167096B (enExample) * | 1985-04-04 | 1990-09-01 | Akzo Nv | |
| US4666705A (en) * | 1985-06-03 | 1987-05-19 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
| GB8628728D0 (en) * | 1986-12-02 | 1987-01-07 | Euro Celtique Sa | Spheroids |
| GB8705083D0 (en) * | 1987-03-04 | 1987-04-08 | Euro Celtique Sa | Spheroids |
| EP0366058A3 (en) * | 1988-10-27 | 1991-03-20 | Abbott Laboratories | Controlled-release delivery device, method for producing device, and method of using device |
-
1990
- 1990-08-01 GB GB909016885A patent/GB9016885D0/en active Pending
-
1991
- 1991-07-15 IT ITMI911953A patent/IT1251788B/it active IP Right Grant
- 1991-07-15 IN IN627DE1991 patent/IN178446B/en unknown
- 1991-07-16 NZ NZ238981A patent/NZ238981A/en not_active IP Right Cessation
- 1991-07-16 ZA ZA915565A patent/ZA915565B/xx unknown
- 1991-07-19 BE BE9100685A patent/BE1004772A3/fr not_active IP Right Cessation
- 1991-07-22 CH CH2179/91A patent/CH682715A5/fr not_active IP Right Cessation
- 1991-07-22 MY MYPI91001315A patent/MY107500A/en unknown
- 1991-07-23 US US07/734,493 patent/US5213812A/en not_active Expired - Lifetime
- 1991-07-25 LU LU87982A patent/LU87982A1/fr unknown
- 1991-07-26 SE SE9102249A patent/SE505734C2/sv unknown
- 1991-07-30 NL NL9101306A patent/NL194637C/nl not_active IP Right Cessation
- 1991-07-30 TN TNTNSN91067A patent/TNSN91067A1/fr unknown
- 1991-07-30 PT PT98497A patent/PT98497B/pt not_active IP Right Cessation
- 1991-07-30 ES ES09101785A patent/ES2046083B1/es not_active Expired - Fee Related
- 1991-07-30 GR GR910100330A patent/GR1001512B/el not_active IP Right Cessation
- 1991-07-31 IE IE270091A patent/IE65124B1/en not_active IP Right Cessation
- 1991-07-31 KR KR1019910013237A patent/KR920003962A/ko not_active Ceased
- 1991-07-31 AT AT0152591A patent/AT396425B/de not_active IP Right Cessation
- 1991-07-31 FI FI913646A patent/FI104149B/fi active
- 1991-07-31 NO NO912986A patent/NO300158B1/no not_active IP Right Cessation
- 1991-07-31 DK DK199101418A patent/DK175756B1/da not_active IP Right Cessation
- 1991-07-31 AU AU81466/91A patent/AU649696B2/en not_active Ceased
- 1991-08-01 DE DE4125542A patent/DE4125542A1/de not_active Withdrawn
- 1991-08-01 FR FR9109773A patent/FR2665360B1/fr not_active Expired - Fee Related
- 1991-08-01 CA CA002048270A patent/CA2048270C/en not_active Expired - Lifetime
- 1991-08-01 JP JP3192950A patent/JP2818704B2/ja not_active Expired - Fee Related
- 1991-08-01 MA MA22524A patent/MA22245A1/fr unknown
- 1991-08-01 OA OA60055A patent/OA09387A/xx unknown
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1994
- 1994-04-11 AU AU59393/94A patent/AU666808B2/en not_active Ceased
- 1994-04-14 HK HK33294A patent/HK33294A/xx not_active IP Right Cessation
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