CH682715A5 - Procédé de préparation de compositions à libération prolongée et compositions ainsi obtenues. - Google Patents
Procédé de préparation de compositions à libération prolongée et compositions ainsi obtenues. Download PDFInfo
- Publication number
- CH682715A5 CH682715A5 CH2179/91A CH217991A CH682715A5 CH 682715 A5 CH682715 A5 CH 682715A5 CH 2179/91 A CH2179/91 A CH 2179/91A CH 217991 A CH217991 A CH 217991A CH 682715 A5 CH682715 A5 CH 682715A5
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- CH
- Switzerland
- Prior art keywords
- gel
- particles
- mpa
- viscosity
- phase
- Prior art date
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- XZZXIYZZBJDEEP-UHFFFAOYSA-N imipramine hydrochloride Chemical compound [Cl-].C1CC2=CC=CC=C2N(CCC[NH+](C)C)C2=CC=CC=C21 XZZXIYZZBJDEEP-UHFFFAOYSA-N 0.000 description 1
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- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
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- RWHUEXWOYVBUCI-ITQXDASVSA-N nafarelin Chemical compound C([C@@H](C(=O)N[C@H](CC=1C=C2C=CC=CC2=CC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1[C@@H](CCC1)C(=O)NCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H]1NC(=O)CC1)C1=CC=C(O)C=C1 RWHUEXWOYVBUCI-ITQXDASVSA-N 0.000 description 1
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- WEXRUCMBJFQVBZ-UHFFFAOYSA-N pentobarbital Chemical compound CCCC(C)C1(CC)C(=O)NC(=O)NC1=O WEXRUCMBJFQVBZ-UHFFFAOYSA-N 0.000 description 1
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- 229960003147 reserpine Drugs 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Biological Depolymerization Polymers (AREA)
- Glanulating (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909016885A GB9016885D0 (en) | 1990-08-01 | 1990-08-01 | Sustained release pharmaceutical compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH682715A5 true CH682715A5 (fr) | 1993-11-15 |
Family
ID=10679993
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH2179/91A CH682715A5 (fr) | 1990-08-01 | 1991-07-22 | Procédé de préparation de compositions à libération prolongée et compositions ainsi obtenues. |
Country Status (30)
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| JP (1) | JP2818704B2 (enExample) |
| KR (1) | KR920003962A (enExample) |
| AT (1) | AT396425B (enExample) |
| AU (2) | AU649696B2 (enExample) |
| BE (1) | BE1004772A3 (enExample) |
| CA (1) | CA2048270C (enExample) |
| CH (1) | CH682715A5 (enExample) |
| DE (1) | DE4125542A1 (enExample) |
| DK (1) | DK175756B1 (enExample) |
| ES (1) | ES2046083B1 (enExample) |
| FI (1) | FI104149B (enExample) |
| FR (1) | FR2665360B1 (enExample) |
| GB (1) | GB9016885D0 (enExample) |
| GR (1) | GR1001512B (enExample) |
| HK (1) | HK33294A (enExample) |
| IE (1) | IE65124B1 (enExample) |
| IN (1) | IN178446B (enExample) |
| IT (1) | IT1251788B (enExample) |
| LU (1) | LU87982A1 (enExample) |
| MA (1) | MA22245A1 (enExample) |
| MY (1) | MY107500A (enExample) |
| NL (1) | NL194637C (enExample) |
| NO (1) | NO300158B1 (enExample) |
| NZ (1) | NZ238981A (enExample) |
| OA (1) | OA09387A (enExample) |
| PT (1) | PT98497B (enExample) |
| SE (1) | SE505734C2 (enExample) |
| TN (1) | TNSN91067A1 (enExample) |
| ZA (1) | ZA915565B (enExample) |
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| GB9310030D0 (en) * | 1993-05-15 | 1993-06-30 | Scras | Dry processed particles and process for the preparation of the same |
| US5569467A (en) * | 1993-05-15 | 1996-10-29 | Societe De Conseils De Recherches Et D'applications (S.C.R.A.S.) | Process for the preparation of microballs and microballs thus obtained |
| DE69529054T2 (de) * | 1994-02-28 | 2003-08-21 | Nanopharm Ag | System zur gezielten wirkstoffzufuhr, verfahren zu seiner herstellung und verwendung |
| US5980945A (en) * | 1996-01-16 | 1999-11-09 | Societe De Conseils De Recherches Et D'applications Scientifique S.A. | Sustained release drug formulations |
| DE19604744A1 (de) | 1996-02-09 | 1997-08-14 | Henkel Kgaa | Technische Di-/Triglyceridgemische |
| DE19617137C1 (de) * | 1996-04-29 | 1997-02-27 | Henkel Kgaa | Verwendung von Copolymerestern für die Herstellung von Mikrosphären |
| EP0930874A2 (en) * | 1996-10-09 | 1999-07-28 | Takeda Chemical Industries, Ltd. | A method for producing a microparticle |
| TW577759B (en) * | 1997-04-18 | 2004-03-01 | Ipsen Pharma Biotech | Sustained release compositions in the form of microcapsules or implants and the process for their preparation |
| AU3555599A (en) | 1998-04-13 | 1999-11-01 | Luminex Corporation | Liquid labeling with fluorescent microparticles |
| IL143761A0 (en) * | 1998-12-16 | 2002-04-21 | Aventis Pharma Inc | Biodegradable polymer encapsulated serotonin receptor antagonist and method for preparing the same |
| AU5644400A (en) * | 1999-09-24 | 2001-03-29 | Rohm And Haas Company | Pellet compositions |
| US6458387B1 (en) * | 1999-10-18 | 2002-10-01 | Epic Therapeutics, Inc. | Sustained release microspheres |
| DE60138641D1 (de) | 2000-10-27 | 2009-06-18 | Baxter Healthcare Sa | Herstellung von mikrokügelchen |
| US20080026068A1 (en) * | 2001-08-16 | 2008-01-31 | Baxter Healthcare S.A. | Pulmonary delivery of spherical insulin microparticles |
| ES2307779T3 (es) * | 2001-08-16 | 2008-12-01 | Baxter International Inc. | Formulaciones de microparticulas a base de propelentes. |
| FR2848113B1 (fr) * | 2002-12-04 | 2005-02-25 | Oreal | Stabilisation de principes actifs aromatiques par des polymeres aromatiques |
| US20040166077A1 (en) * | 2002-12-04 | 2004-08-26 | L'oreal | Process for treating keratin materials with aromatic active principles |
| BRPI0412735A (pt) * | 2003-07-18 | 2006-09-26 | Baxter Int | métodos para a fabricação, uso e composição de partìculas esféricas pequenas preparadas mediante a separação de fase controlada |
| US20050142205A1 (en) * | 2003-07-18 | 2005-06-30 | Julia Rashba-Step | Methods for encapsulating small spherical particles prepared by controlled phase separation |
| US20070092452A1 (en) * | 2003-07-18 | 2007-04-26 | Julia Rashba-Step | Methods for fabrication, uses, compositions of inhalable spherical particles |
| JP2007508240A (ja) * | 2003-07-22 | 2007-04-05 | バクスター・インターナショナル・インコーポレイテッド | 低分子量有機分子の小球状粒子ならびにその調製方法および使用方法 |
| US20060135277A1 (en) * | 2003-09-10 | 2006-06-22 | Marnocha Bendict F | Golf club and practice arrangement |
| FR2865938B1 (fr) * | 2004-02-05 | 2006-06-02 | Sod Conseils Rech Applic | Formulation retard solide comprenant de l'acetate de triptoreline |
| JP2007537288A (ja) * | 2004-05-12 | 2007-12-20 | バクスター インターナショナル インコーポレイテッド | オリゴヌクレオチド含有マイクロスフェア、１型糖尿病を処置する医薬の製造のための、その使用 |
| EP2335689A1 (en) * | 2004-05-12 | 2011-06-22 | Baxter International Inc. | Method of manufacturing nucleic acid micropheres |
| US8728525B2 (en) * | 2004-05-12 | 2014-05-20 | Baxter International Inc. | Protein microspheres retaining pharmacokinetic and pharmacodynamic properties |
| WO2005112893A1 (en) * | 2004-05-12 | 2005-12-01 | Baxter International Inc. | Microspheres comprising protein and showing injectability at high concentrations of said agent |
| JP2008506700A (ja) * | 2004-07-13 | 2008-03-06 | アルテアーナノ，インコーポレーテッド | 薬物の制御された放出のためのセラミック構造体 |
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| EP1885335A1 (en) * | 2005-04-27 | 2008-02-13 | BAXTER INTERNATIONAL INC. (a Delaware corporation) | Surface-modified microparticles and methods of forming and using the same |
| CA2620167A1 (en) * | 2005-08-23 | 2007-03-01 | Altairnano, Inc. | Highly photocatalytic phosphorus-doped anatase-tio2 composition and related manufacturing methods |
| US20080020175A1 (en) * | 2006-03-02 | 2008-01-24 | Fred Ratel | Nanostructured Indium-Doped Iron Oxide |
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| WO2007103829A1 (en) * | 2006-03-02 | 2007-09-13 | Altairnano, Inc. | Method for production of metal oxide coatings |
| US20070281031A1 (en) * | 2006-06-01 | 2007-12-06 | Guohan Yang | Microparticles and methods for production thereof |
| JP5118139B2 (ja) | 2006-08-04 | 2013-01-16 | バクスター・インターナショナル・インコーポレイテッド | 新規発症自己免疫性糖尿病を予防および／または逆転させるためのマイクロスフィアに基づく組成物 |
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| EP3590503A1 (en) | 2006-10-12 | 2020-01-08 | The University of Queensland | Compositions and methods for modulating immune responses |
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| US4666705A (en) * | 1985-06-03 | 1987-05-19 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
| GB8628728D0 (en) * | 1986-12-02 | 1987-01-07 | Euro Celtique Sa | Spheroids |
| GB8705083D0 (en) * | 1987-03-04 | 1987-04-08 | Euro Celtique Sa | Spheroids |
| AU4369589A (en) * | 1988-10-27 | 1990-05-03 | Abbott Laboratories | Controlled-release delivery device, method for producing device, and method of using device |
-
1990
- 1990-08-01 GB GB909016885A patent/GB9016885D0/en active Pending
-
1991
- 1991-07-15 IN IN627DE1991 patent/IN178446B/en unknown
- 1991-07-15 IT ITMI911953A patent/IT1251788B/it active IP Right Grant
- 1991-07-16 ZA ZA915565A patent/ZA915565B/xx unknown
- 1991-07-16 NZ NZ238981A patent/NZ238981A/en not_active IP Right Cessation
- 1991-07-19 BE BE9100685A patent/BE1004772A3/fr not_active IP Right Cessation
- 1991-07-22 CH CH2179/91A patent/CH682715A5/fr not_active IP Right Cessation
- 1991-07-22 MY MYPI91001315A patent/MY107500A/en unknown
- 1991-07-23 US US07/734,493 patent/US5213812A/en not_active Expired - Lifetime
- 1991-07-25 LU LU87982A patent/LU87982A1/fr unknown
- 1991-07-26 SE SE9102249A patent/SE505734C2/sv unknown
- 1991-07-30 TN TNTNSN91067A patent/TNSN91067A1/fr unknown
- 1991-07-30 ES ES09101785A patent/ES2046083B1/es not_active Expired - Fee Related
- 1991-07-30 PT PT98497A patent/PT98497B/pt not_active IP Right Cessation
- 1991-07-30 NL NL9101306A patent/NL194637C/nl not_active IP Right Cessation
- 1991-07-30 GR GR910100330A patent/GR1001512B/el not_active IP Right Cessation
- 1991-07-31 AT AT0152591A patent/AT396425B/de not_active IP Right Cessation
- 1991-07-31 AU AU81466/91A patent/AU649696B2/en not_active Ceased
- 1991-07-31 KR KR1019910013237A patent/KR920003962A/ko not_active Ceased
- 1991-07-31 NO NO912986A patent/NO300158B1/no not_active IP Right Cessation
- 1991-07-31 FI FI913646A patent/FI104149B/fi active
- 1991-07-31 DK DK199101418A patent/DK175756B1/da not_active IP Right Cessation
- 1991-07-31 IE IE270091A patent/IE65124B1/en not_active IP Right Cessation
- 1991-08-01 OA OA60055A patent/OA09387A/xx unknown
- 1991-08-01 MA MA22524A patent/MA22245A1/fr unknown
- 1991-08-01 DE DE4125542A patent/DE4125542A1/de not_active Withdrawn
- 1991-08-01 CA CA002048270A patent/CA2048270C/en not_active Expired - Lifetime
- 1991-08-01 JP JP3192950A patent/JP2818704B2/ja not_active Expired - Fee Related
- 1991-08-01 FR FR9109773A patent/FR2665360B1/fr not_active Expired - Fee Related
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1994
- 1994-04-11 AU AU59393/94A patent/AU666808B2/en not_active Ceased
- 1994-04-14 HK HK33294A patent/HK33294A/xx not_active IP Right Cessation
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| PL | Patent ceased |