ES2042828T3 - Procedimiento de preparacion de vacunas contra tumores modificadas por virus para la inmunoterapia de metastasis de tumores. - Google Patents
Procedimiento de preparacion de vacunas contra tumores modificadas por virus para la inmunoterapia de metastasis de tumores.Info
- Publication number
- ES2042828T3 ES2042828T3 ES89103480T ES89103480T ES2042828T3 ES 2042828 T3 ES2042828 T3 ES 2042828T3 ES 89103480 T ES89103480 T ES 89103480T ES 89103480 T ES89103480 T ES 89103480T ES 2042828 T3 ES2042828 T3 ES 2042828T3
- Authority
- ES
- Spain
- Prior art keywords
- immunotherapy
- tumor
- preparation procedure
- vaccine preparation
- virus modified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 241000700605 Viruses Species 0.000 title abstract 3
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 206010027476 Metastases Diseases 0.000 title 1
- 238000009169 immunotherapy Methods 0.000 title 1
- 230000009401 metastasis Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 230000005855 radiation Effects 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5152—Tumor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5156—Animal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
- A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
- C12N2760/18133—Use of viral protein as therapeutic agent other than vaccine, e.g. apoptosis inducing or anti-inflammatory
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3806565A DE3806565A1 (de) | 1988-03-01 | 1988-03-01 | Virusmodifizierte tumorvakzinen fuer die immuntherapie von tumormetastasen |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2042828T3 true ES2042828T3 (es) | 1993-12-16 |
Family
ID=6348527
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES89103480T Expired - Lifetime ES2042828T3 (es) | 1988-03-01 | 1989-02-27 | Procedimiento de preparacion de vacunas contra tumores modificadas por virus para la inmunoterapia de metastasis de tumores. |
Country Status (10)
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3922444A1 (de) * | 1988-03-01 | 1991-01-10 | Deutsches Krebsforsch | Virusmodifizierte tumorvakzine fuer die immuntherapie von tumormetastasen |
DE4204132C2 (de) * | 1991-02-12 | 1997-12-18 | Rudolf Dr Pekar | Aufbereitung für die Gewinnung von Vakzinen für eine Immuntherapie |
DE69232890T2 (de) * | 1991-10-04 | 2003-10-09 | The Johns Hopkins University School Of Medicine, Baltimore | Regulierung der systemischen immunantworten mittels zytokinen und antigenen |
ATE411809T1 (de) * | 1993-04-30 | 2008-11-15 | Wellstat Biologics Corp | Zusuammensetzungen zur behandlung von krebs mittels viren |
DE19506483A1 (de) * | 1995-02-24 | 1996-08-29 | Jens Dr Dr Atzpodien | Lyophilisat-Vakzine |
US6406689B1 (en) | 1995-10-03 | 2002-06-18 | Frank W. Falkenberg | Compositions and methods for treatment of tumors and metastatic diseases |
EP0805207A1 (en) * | 1996-05-02 | 1997-11-05 | Gesellschaft für Biotechnologische Forschung mbH (GBF) | Polycistronic expression plasmid for tumor rejection |
ATE245163T1 (de) * | 1996-05-03 | 2003-08-15 | Univ Jefferson | Impfstoff gegen metastasierenden kolorektalkrebs. |
CA2242590A1 (en) * | 1996-10-04 | 1998-04-09 | Thomas Jefferson University | T cells mediating an immune response and methods of use |
DE69731950T2 (de) * | 1997-08-22 | 2005-05-19 | Science Park Raf S.P.A. | Tumorvakzinierung mittels Verwendung autologer oder HLA-verwandter Antigen präsentierender Zellen (APC), die mit einem Tumorantigen sowie einem eine Immunantwort hervorrufenden Fremdantigen transduziert sind |
TW575420B (en) * | 1997-09-22 | 2004-02-11 | Kirin Brewery | Composition for enhancing cellular immunogenicity comprising alpha-glycosylceramides |
US20030044384A1 (en) * | 1997-10-09 | 2003-03-06 | Pro-Virus, Inc. | Treatment of neoplasms with viruses |
US7470426B1 (en) | 1997-10-09 | 2008-12-30 | Wellstat Biologics Corporation | Treatment of neoplasms with viruses |
WO2000062735A2 (en) * | 1999-04-15 | 2000-10-26 | Pro-Virus, Inc. | Treatment of neoplasms with viruses |
US7780962B2 (en) * | 1997-10-09 | 2010-08-24 | Wellstat Biologics Corporation | Treatment of neoplasms with RNA viruses |
US8147822B1 (en) | 1999-09-17 | 2012-04-03 | Wellstat Biologics Corporation | Oncolytic virus |
EP1092439A1 (en) * | 1999-10-13 | 2001-04-18 | Thorsten Dr. Ahlert | Activation of antigen-specific T cells by virus/antigen-treated dendritic cells |
RU2172182C1 (ru) * | 2000-07-27 | 2001-08-20 | Бритов Василий Александрович | Способ профилактики и лечения заболеваний иммунной системы и средство для его осуществления |
KR20040094635A (ko) * | 2003-05-02 | 2004-11-10 | 주식회사 엠디바이오알파 | 항종양 활성의 유도를 위한 종양 백신의 제조방법 및그것을 함유하고 있는 약제 조성물 |
ES2668464T3 (es) | 2005-12-02 | 2018-05-18 | Icahn School Of Medicine At Mount Sinai | Virus quiméricos de la enfermedad de Newcastle que presentan proteínas de superficie no naturales y sus usos |
US9283266B2 (en) * | 2008-02-28 | 2016-03-15 | University Of Notre Dame | Metastasis inhibition preparations and methods |
US8586023B2 (en) | 2008-09-12 | 2013-11-19 | Mie University | Cell capable of expressing exogenous GITR ligand |
US20110206736A1 (en) * | 2008-09-23 | 2011-08-25 | Thomas Jefferson University | Cancer Vaccines Against Mucosal Antigens and Methods of Making and Using the Same |
EP2327764B1 (en) * | 2009-11-30 | 2011-12-28 | United Cancer Research Institute | New clone of Newcastle disease virus, its manufacture and its application in the medical treatment of cancer |
SG10201802982WA (en) | 2013-03-14 | 2018-06-28 | Icahn School Med Mount Sinai | Newcastle disease viruses and uses thereof |
CA2940570A1 (en) | 2014-02-27 | 2015-09-03 | Viralytics Limited | Combination method for treatment of cancer |
JOP20190256A1 (ar) | 2017-05-12 | 2019-10-28 | Icahn School Med Mount Sinai | فيروسات داء نيوكاسل واستخداماتها |
US12391957B2 (en) | 2018-08-17 | 2025-08-19 | Icahn School Of Medicine At Mount Sinai | Recombinant Newcastle disease viruses and uses thereof for the prevention of RSV disease or human metapneumovirus disease |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2918927A1 (de) * | 1979-05-10 | 1980-11-20 | Hans Prof Dr Limburg | Arzneipraeparat zur behandlung von carcinomen und verfahren zu dessen herstellung |
DE3432714A1 (de) * | 1984-09-06 | 1986-04-24 | Behringwerke Ag, 3550 Marburg | Tumortherapeutikum und verfahren zu seiner herstellung |
HU197517B (en) * | 1984-07-30 | 1989-04-28 | Laszlo Csatary | Process for production of terapeutical composition applicable against virus infection |
-
1988
- 1988-03-01 DE DE3806565A patent/DE3806565A1/de active Granted
-
1989
- 1989-02-27 AU AU31889/89A patent/AU3188989A/en not_active Abandoned
- 1989-02-27 KR KR1019890702004A patent/KR900700130A/ko not_active Withdrawn
- 1989-02-27 US US07/449,851 patent/US5273745A/en not_active Expired - Fee Related
- 1989-02-27 JP JP1502563A patent/JPH02504034A/ja active Pending
- 1989-02-27 EP EP19890103480 patent/EP0331102B1/de not_active Expired - Lifetime
- 1989-02-27 DE DE8989103480T patent/DE58904760D1/de not_active Expired - Fee Related
- 1989-02-27 AT AT89103480T patent/ATE90877T1/de active
- 1989-02-27 WO PCT/EP1989/000186 patent/WO1989007946A1/de unknown
- 1989-02-27 ES ES89103480T patent/ES2042828T3/es not_active Expired - Lifetime
- 1989-10-31 DK DK541889A patent/DK541889D0/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DE58904760D1 (de) | 1993-07-29 |
EP0331102A1 (de) | 1989-09-06 |
EP0331102B1 (de) | 1993-06-23 |
KR900700130A (ko) | 1990-08-11 |
AU3188989A (en) | 1989-09-22 |
JPH02504034A (ja) | 1990-11-22 |
DK541889A (da) | 1989-10-31 |
DK541889D0 (da) | 1989-10-31 |
US5273745A (en) | 1993-12-28 |
DE3806565A1 (de) | 1989-09-14 |
ATE90877T1 (de) | 1993-07-15 |
DE3806565C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1991-04-25 |
WO1989007946A1 (en) | 1989-09-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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