CY1106635T1 - Ανοσοενισχυτικο που περιεχει ν - φορμυλο μεθειονυλο-πεπτιδια για εμβολια - Google Patents
Ανοσοενισχυτικο που περιεχει ν - φορμυλο μεθειονυλο-πεπτιδια για εμβολιαInfo
- Publication number
- CY1106635T1 CY1106635T1 CY20071100731T CY071100731T CY1106635T1 CY 1106635 T1 CY1106635 T1 CY 1106635T1 CY 20071100731 T CY20071100731 T CY 20071100731T CY 071100731 T CY071100731 T CY 071100731T CY 1106635 T1 CY1106635 T1 CY 1106635T1
- Authority
- CY
- Cyprus
- Prior art keywords
- immunoproduct
- vaccines
- peptide containing
- formyl methionyl
- formyl
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title 1
- PRQROPMIIGLWRP-UHFFFAOYSA-N N-formyl-methionyl-leucyl-phenylalanin Chemical compound CSCCC(NC=O)C(=O)NC(CC(C)C)C(=O)NC(C(O)=O)CC1=CC=CC=C1 PRQROPMIIGLWRP-UHFFFAOYSA-N 0.000 abstract 2
- 239000002671 adjuvant Substances 0.000 abstract 2
- -1 N-formyl methionyl Chemical group 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/21—Retroviridae, e.g. equine infectious anemia virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/826—Viruses
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/915—Therapeutic or pharmaceutical composition
- Y10S977/917—Vaccine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/918—Immunological
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/92—Detection of biochemical
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Oncology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Abstract
Η παρούσα εφεύρεση σχετίζεται με ανοσολογικά ανοσοενισχυτικά που αποτελούνται από το Ν-φορμυλο μεθειονυλο πεπτίδιο fMLP. To fMLP, όταν χρησιμοποιείται ως ένα ανοσοενισχυτικό σε συμφωνία με την παρούσα εφεύρεση, φροντίζει για μία ανοσοαπόκριση σε υπο-βέλτιστες δόσεις των ανασυνδυασμένων αντιγόνων.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/216,702 US6017537A (en) | 1998-12-18 | 1998-12-18 | Formyl methionyl peptide vaccine adjuvant |
PCT/US1999/030188 WO2000035482A2 (en) | 1998-12-18 | 1999-12-17 | Novel adjuvant for subunit or component vaccines |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1106635T1 true CY1106635T1 (el) | 2012-01-25 |
Family
ID=22808169
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20071100731T CY1106635T1 (el) | 1998-12-18 | 2007-06-04 | Ανοσοενισχυτικο που περιεχει ν - φορμυλο μεθειονυλο-πεπτιδια για εμβολια |
CY20111100355T CY1111372T1 (el) | 1998-12-18 | 2011-04-05 | Ανοσολογικη συνθεση και εμβολια που περιεχουν ν-φορμυλομεθειονυλο πεπτιδιο ως ανοσοενισχυτικο |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20111100355T CY1111372T1 (el) | 1998-12-18 | 2011-04-05 | Ανοσολογικη συνθεση και εμβολια που περιεχουν ν-φορμυλομεθειονυλο πεπτιδιο ως ανοσοενισχυτικο |
Country Status (15)
Country | Link |
---|---|
US (1) | US6017537A (el) |
EP (2) | EP1140166B1 (el) |
JP (1) | JP2002532436A (el) |
AT (2) | ATE359817T1 (el) |
AU (1) | AU773697B2 (el) |
CA (2) | CA2718376A1 (el) |
CY (2) | CY1106635T1 (el) |
DE (2) | DE69943170D1 (el) |
DK (2) | DK1140166T3 (el) |
ES (2) | ES2284285T3 (el) |
HK (1) | HK1110769A1 (el) |
NZ (1) | NZ510544A (el) |
PT (2) | PT1800692E (el) |
SI (2) | SI1140166T1 (el) |
WO (1) | WO2000035482A2 (el) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20010018579A1 (en) | 1998-12-18 | 2001-08-30 | Walter Klemp | Disposable absorbent garment having stretchable side waist regions |
GB9924351D0 (en) | 1999-10-14 | 1999-12-15 | Brennan Frank | Immunomodulation methods and compositions |
WO2001089552A1 (en) * | 2000-05-23 | 2001-11-29 | Histatek, Llc | Modulaton of alpha-6 integrin-mediated responses |
AU2002232560A1 (en) * | 2000-10-27 | 2002-05-06 | Immuno-Rx, Inc | Vaccine immunotherapy for immune suppressed patients |
US20070025958A1 (en) * | 2000-10-27 | 2007-02-01 | Hadden John W | Vaccine immunotherapy |
MXPA05003049A (es) | 2002-09-19 | 2005-11-17 | Us Gov Health & Human Serv | Polipeptidos de phlebotomus ariasi, polipeptidos de phlebotomus perniciosus y metodos de uso. |
ES2447843T3 (es) | 2002-10-29 | 2014-03-13 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Polip�ptidos de Lutzomyia longipalpis y m�todos de uso |
CA2512798A1 (en) * | 2003-01-07 | 2004-07-22 | Neuromed Technologies, Inc. | Fluorescence based t-type channel assay |
EP1734991A4 (en) * | 2004-04-14 | 2012-10-24 | Avirid Inc | COMPOSITIONS COMPRISING MODIFIED NUCLEASES DIRECTED AGAINST VIRAL NUCLEIC ACIDS AND METHODS OF USE FOR THE PREVENTION AND TREATMENT OF VIRAL DISEASES |
US7998733B2 (en) | 2004-10-05 | 2011-08-16 | Merial Limited | Chimeric vectors |
AU2006210392A1 (en) | 2005-02-04 | 2006-08-10 | Coley Pharmaceutical Group, Inc. | Aqueous gel formulations containing immune response modifiers |
US7887522B2 (en) | 2005-03-18 | 2011-02-15 | The Procter And Gamble Company | Pull-on wearable article with informational image |
US7806880B2 (en) * | 2005-03-18 | 2010-10-05 | The Procter & Gamble Company | Pull-on wearable article with informational image |
US20060264858A1 (en) * | 2005-05-20 | 2006-11-23 | Roe Donald C | Multi-functional training garment |
WO2007022151A2 (en) | 2005-08-15 | 2007-02-22 | Vaxin, Inc. | Immunization of avians by administration of non-replicating vectored vaccines |
US7432413B2 (en) | 2005-12-16 | 2008-10-07 | The Procter And Gamble Company | Disposable absorbent article having side panels with structurally, functionally and visually different regions |
US8664467B2 (en) | 2006-03-31 | 2014-03-04 | The Procter & Gamble Company | Absorbent articles with feedback signal upon urination |
EP3669894A3 (en) * | 2006-06-30 | 2020-08-26 | Syntab Therapeutics GmbH | Novel multifunctional compounds for pharmaceutical purposes |
CA2851763A1 (en) | 2006-12-04 | 2008-06-12 | The Procter & Gamble Company | Absorbent articles comprising graphics |
MX2010012069A (es) | 2008-05-08 | 2010-12-14 | Merial Ltd | Vacuna de la leishmaniasis con el uso del inmunogeno salival de la mosca de la arena. |
US9400873B2 (en) | 2011-12-21 | 2016-07-26 | Deka Products Limited Partnership | System, method, and apparatus for dispensing oral medications |
CA2793959C (en) | 2010-03-25 | 2019-06-04 | Oregon Health & Science University | Cmv glycoproteins and recombinant vectors |
EP2691530B1 (en) | 2011-06-10 | 2018-03-07 | Oregon Health & Science University | Cmv glycoproteins and recombinant vectors |
CN103957932B (zh) | 2011-07-20 | 2017-06-23 | 梅里亚有限公司 | 包含最优化的猫白血病病毒包膜基因的重组猫白血病病毒疫苗 |
WO2013025274A1 (en) | 2011-08-12 | 2013-02-21 | Merial Limited | Vacuum -assisted preservation of biological products, in particular of vaccines |
US20130189754A1 (en) | 2011-09-12 | 2013-07-25 | International Aids Vaccine Initiative | Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies |
US9402894B2 (en) | 2011-10-27 | 2016-08-02 | International Aids Vaccine Initiative | Viral particles derived from an enveloped virus |
US10563681B2 (en) | 2011-12-21 | 2020-02-18 | Deka Products Limited Partnership | System, method, and apparatus for clamping |
WO2013142371A1 (en) | 2012-03-20 | 2013-09-26 | Merial Limited | Recombinant equine herpesvirus-1 vaccine containing mutated glycoprotein c and uses thereof |
WO2013170433A1 (en) | 2012-05-15 | 2013-11-21 | The Procter & Gamble Company | Absorbent article having characteristic waist end |
ES2631608T3 (es) | 2012-06-27 | 2017-09-01 | International Aids Vaccine Initiative | Variante de la glicoproteína Env del VIH-1 |
US20150065381A1 (en) | 2013-09-05 | 2015-03-05 | International Aids Vaccine Initiative | Methods of identifying novel hiv-1 immunogens |
EP2873423B1 (en) | 2013-10-07 | 2017-05-31 | International Aids Vaccine Initiative | Soluble hiv-1 envelope glycoprotein trimers |
NZ726315A (en) | 2014-05-14 | 2018-04-27 | Merial Inc | Methods for freeze-drying and rehydrating biologics |
US10174292B2 (en) | 2015-03-20 | 2019-01-08 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
EP3072901A1 (en) | 2015-03-23 | 2016-09-28 | International Aids Vaccine Initiative | Soluble hiv-1 envelope glycoprotein trimers |
WO2023282436A1 (ko) * | 2021-07-09 | 2023-01-12 | 포항공과대학교 산학협력단 | 포밀 메티오닌 특이 항체 제조를 위한 신규한 항원 펩타이드 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL89118A0 (en) * | 1988-02-03 | 1989-08-15 | Microgenesys Inc | Vaccine containing polypeptides derived from the envelope gene of human immunodeficiency virus type 1 |
US5861158A (en) * | 1993-11-17 | 1999-01-19 | The United States Of America As Represented By The Deptartment Of Health And Human Services | Method and composition for transfer of active tumor-specific immunization from an immunized allogeneic bone marrow donor |
-
1998
- 1998-12-18 US US09/216,702 patent/US6017537A/en not_active Expired - Lifetime
-
1999
- 1999-12-17 DE DE69943170T patent/DE69943170D1/de not_active Expired - Lifetime
- 1999-12-17 DE DE69935866T patent/DE69935866T2/de not_active Expired - Lifetime
- 1999-12-17 AU AU28451/00A patent/AU773697B2/en not_active Ceased
- 1999-12-17 NZ NZ510544A patent/NZ510544A/xx not_active IP Right Cessation
- 1999-12-17 ES ES99969285T patent/ES2284285T3/es not_active Expired - Lifetime
- 1999-12-17 AT AT99969285T patent/ATE359817T1/de active
- 1999-12-17 CA CA2718376A patent/CA2718376A1/en not_active Abandoned
- 1999-12-17 SI SI9930961T patent/SI1140166T1/sl unknown
- 1999-12-17 PT PT07007842T patent/PT1800692E/pt unknown
- 1999-12-17 AT AT07007842T patent/ATE496630T1/de active
- 1999-12-17 DK DK99969285T patent/DK1140166T3/da active
- 1999-12-17 PT PT99969285T patent/PT1140166E/pt unknown
- 1999-12-17 CA CA2342609A patent/CA2342609C/en not_active Expired - Fee Related
- 1999-12-17 JP JP2000587801A patent/JP2002532436A/ja active Pending
- 1999-12-17 WO PCT/US1999/030188 patent/WO2000035482A2/en active IP Right Grant
- 1999-12-17 SI SI9931051T patent/SI1800692T1/sl unknown
- 1999-12-17 ES ES07007842T patent/ES2358540T3/es not_active Expired - Lifetime
- 1999-12-17 EP EP99969285A patent/EP1140166B1/en not_active Expired - Lifetime
- 1999-12-17 DK DK07007842.3T patent/DK1800692T3/da active
- 1999-12-17 EP EP07007842A patent/EP1800692B1/en not_active Expired - Lifetime
-
2007
- 2007-06-04 CY CY20071100731T patent/CY1106635T1/el unknown
- 2007-12-24 HK HK07114096.7A patent/HK1110769A1/xx not_active IP Right Cessation
-
2011
- 2011-04-05 CY CY20111100355T patent/CY1111372T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
HK1110769A1 (en) | 2008-07-25 |
EP1800692B1 (en) | 2011-01-26 |
EP1800692A1 (en) | 2007-06-27 |
SI1800692T1 (sl) | 2011-05-31 |
ATE359817T1 (de) | 2007-05-15 |
DE69935866D1 (de) | 2007-05-31 |
WO2000035482A2 (en) | 2000-06-22 |
PT1800692E (pt) | 2011-03-31 |
DK1140166T3 (da) | 2007-07-02 |
CA2718376A1 (en) | 2000-06-22 |
CY1111372T1 (el) | 2015-08-05 |
ES2284285T3 (es) | 2007-11-01 |
DE69943170D1 (de) | 2011-03-10 |
US6017537A (en) | 2000-01-25 |
WO2000035482A3 (en) | 2000-10-26 |
ATE496630T1 (de) | 2011-02-15 |
SI1140166T1 (sl) | 2007-08-31 |
ES2358540T3 (es) | 2011-05-11 |
EP1140166A2 (en) | 2001-10-10 |
AU773697B2 (en) | 2004-06-03 |
CA2342609C (en) | 2010-11-16 |
CA2342609A1 (en) | 2000-06-22 |
EP1140166B1 (en) | 2007-04-18 |
PT1140166E (pt) | 2007-06-27 |
JP2002532436A (ja) | 2002-10-02 |
DK1800692T3 (da) | 2011-03-28 |
AU2845100A (en) | 2000-07-03 |
NZ510544A (en) | 2003-04-29 |
DE69935866T2 (de) | 2008-01-10 |
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