ES2042753T3 - Procedimiento para la preparacion de derivados de nitrometano. - Google Patents

Procedimiento para la preparacion de derivados de nitrometano.

Info

Publication number
ES2042753T3
ES2042753T3 ES88307148T ES88307148T ES2042753T3 ES 2042753 T3 ES2042753 T3 ES 2042753T3 ES 88307148 T ES88307148 T ES 88307148T ES 88307148 T ES88307148 T ES 88307148T ES 2042753 T3 ES2042753 T3 ES 2042753T3
Authority
ES
Spain
Prior art keywords
rent
alkyl
compounds
sulfamoil
carbamoil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88307148T
Other languages
English (en)
Inventor
Steven Paul Brown
Anthony Loren Cooper
Jethro Lawrence Longridge
Jeffrey James Morris
John Preston
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888808117A external-priority patent/GB8808117D0/en
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Application granted granted Critical
Publication of ES2042753T3 publication Critical patent/ES2042753T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE DESCRIBEN COMPUESTOS DE FORMULA Q - SO2 - CH2 - NO2 EN LA QUE Q ES UN GRUPO AROMATICO DE 6, 10 O 14 C QUE LLEVA OPCIONALMENTE 1, 2 O 3 SUSTITUYENTES, QUE SE SELECCIONAN INDEPENDIENTEMENTE DE: H, HALOGENO, CIANO, NITRO, HIDROXI, CARBOXI, AMINO, ALQUILAMINO O DIALQUILAMINO DE HASTA 6 C, ALCANO (DE 1 A 6 C) - AMINO, ALCANOILO DE 1 A 6 C, ALQUILO DE 1 A 6 C, ALQUENILO DE 2 A 6 C, ALQUENILOXI DE 3 A 6 C, FLUOROALQUILO DE 1 A 4 C, ALCOXI (DE 1 A 4 C) - ALQUILO(DE 1 A 4 C), CARBAMOILO, ALQUILO O DIALQUILCARBAMOILO DE HASTA 7 C, SULFAMOILO, ALQUIL - O DIALQUIL - (DE HASTA 6 C) - SULFAMOILO, ALCOXZI(DE 1 A 6 C) CARBONILO, ALQUILEN(DE 1 A 4 C) - DIOXI, ALCANO(DE 1 A 6 C)SULFONAMIDO, ALQUIL(DE 1 A 6 C) - S(O)N (EN EL QUE N ES 0, 1 O 2), FENILO, FENOXI, BENCILOXI, BENCILOXICARBONILO, BENZAMIDO Y BENCENSULFONAMIDO (PUDIENDO LLEVAR EL ANILLO BENCENICO DE ESTOS 6 ULTIMOS GRUPOS UN SUSTITUYENTE HALOGENO, CIANO O ALQUILO O ALCOXI DE 1 A 4 C); O BIEN Q LLEVA 4 O 5 SUSTITUYENTES SELECCIONADOS INDEPENDIENTEMENTE DE HALOGENO, CIANO O ALQUILO O ALCOXI DE 1 A 6 C, PERO EXCLUYENDO LOS COMPUESTOS EN QUE Q ES 2 - CARBOXI FENILO. ESTOS COMPUESTOS SE EMPLEAN EN COMPOSICIONES FARMACEUTICAS Y SE PUEDEN PREPARAR A PARTIR DE: A) UN SULFINATO ALCALINO Y NITROMETANO; B) UNA SULFONA Y UN NITRATO DE ALQUILO, Y C) UN TIOETER.
ES88307148T 1987-08-06 1988-08-03 Procedimiento para la preparacion de derivados de nitrometano. Expired - Lifetime ES2042753T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878718619A GB8718619D0 (en) 1987-08-06 1987-08-06 Pharmaceutical compositions
GB888808117A GB8808117D0 (en) 1988-04-07 1988-04-07 Pharmaceutical compositions

Publications (1)

Publication Number Publication Date
ES2042753T3 true ES2042753T3 (es) 1993-12-16

Family

ID=26292578

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88307148T Expired - Lifetime ES2042753T3 (es) 1987-08-06 1988-08-03 Procedimiento para la preparacion de derivados de nitrometano.

Country Status (24)

Country Link
US (1) US5153227A (es)
EP (1) EP0304190B1 (es)
JP (1) JP2695852B2 (es)
KR (1) KR970008155B1 (es)
AU (1) AU620550B2 (es)
CA (1) CA1338646C (es)
DE (1) DE3872620T2 (es)
DK (1) DK435688A (es)
EG (1) EG18652A (es)
ES (1) ES2042753T3 (es)
FI (1) FI88713C (es)
GB (2) GB8718619D0 (es)
GR (1) GR3005126T3 (es)
HU (1) HU201004B (es)
IE (1) IE60913B1 (es)
IL (1) IL87201A (es)
MY (1) MY103595A (es)
NO (1) NO167797C (es)
NZ (1) NZ225488A (es)
PH (1) PH27185A (es)
PL (2) PL158324B1 (es)
PT (1) PT88201B (es)
YU (2) YU152288A (es)
ZW (1) ZW9988A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8810203D0 (en) * 1988-04-29 1988-06-02 Ici Plc Heterocyclic compounds
DE3823318A1 (de) * 1988-07-09 1990-02-22 Bayer Ag (hetero)aryloxynaphthaline mit ueber schwefel gebundenen substituenten
GB8902406D0 (en) * 1989-02-03 1989-03-22 Ici Plc Process
GB8902409D0 (en) * 1989-02-03 1989-03-22 Ici Plc Aliphatic compounds
GB8902405D0 (en) * 1989-02-03 1989-03-22 Ici Plc Heterocyclic compounds
IL93178A0 (en) * 1989-02-03 1990-11-05 Ici Plc Benzheterocyclyl sulphones
GB8902408D0 (en) * 1989-02-03 1989-03-22 Ici Plc Process
IE63463B1 (en) * 1989-02-06 1995-04-19 Zeneca Ltd Phenylsulphone derivatives
GB8902573D0 (en) * 1989-02-06 1989-03-22 Ici Plc Heterocyclic derivatives
GB9016984D0 (en) * 1990-08-02 1990-09-19 Ici Plc Aniline derivatives
US5250570A (en) * 1990-08-02 1993-10-05 Imperial Chemical Industries Plc Amidobenzene derivatives, compositions and use
GB9016980D0 (en) * 1990-08-02 1990-09-19 Ici Plc Amidobenzenes
GB9016978D0 (en) * 1990-08-02 1990-09-19 Ici Plc Acetamide derivatives
FR2757509B1 (fr) * 1996-12-23 1999-03-26 Lipha Nouveaux derives de sulfonamides et sulfonylurees, leurs preparations et medicaments les contenant
US5932765A (en) 1997-05-23 1999-08-03 Merck Patent Gesellschaft Mit Nitromethyl ketones, process for preparing them and compositions containing them

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3882247A (en) * 1972-04-21 1975-05-06 Du Pont Fungicidal nitro organic sulfur compounds
SU479761A1 (ru) * 1973-07-18 1975-08-05 Институт Органической Химии Им. Н.Д.Зелинского Ан Ссср Способ получени -динитроалкилсульфонов
US4053633A (en) * 1976-06-24 1977-10-11 The Dow Chemical Company Aryl dibromonitromethyl sulfones
FR2432316A1 (fr) * 1978-08-02 1980-02-29 Choay Sa Nouveaux medicaments contenant, a titre de substance active, des composes de type benzenesulfone, nouveaux composes de ce type et procede pour leur preparation
DE3326635A1 (de) * 1983-07-23 1985-01-31 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von monomethylsubstituierten methylen-verbindungen

Also Published As

Publication number Publication date
YU45090A (en) 1992-05-28
JP2695852B2 (ja) 1998-01-14
NO167797B (no) 1991-09-02
HU201004B (en) 1990-09-28
IE60913B1 (en) 1994-08-24
GB8816671D0 (en) 1988-08-17
AU1925488A (en) 1989-02-09
PL274093A1 (en) 1990-02-19
US5153227A (en) 1992-10-06
HUT47243A (en) 1989-02-28
PL281865A1 (en) 1990-07-09
EP0304190A1 (en) 1989-02-22
YU152288A (en) 1990-06-30
GB2207916A (en) 1989-02-15
KR890003365A (ko) 1989-04-14
PT88201B (pt) 1995-03-31
NO883500L (no) 1989-02-07
ZW9988A1 (en) 1990-03-14
KR970008155B1 (ko) 1997-05-21
FI883673A (fi) 1989-02-07
GR3005126T3 (es) 1993-05-24
FI88713B (fi) 1993-03-15
PL157940B1 (pl) 1992-07-31
CA1338646C (en) 1996-10-15
PT88201A (pt) 1989-06-30
NO167797C (no) 1991-12-11
GB2207916B (en) 1992-03-25
NZ225488A (en) 1990-12-21
PH27185A (en) 1993-04-16
FI883673A0 (fi) 1988-08-05
DE3872620T2 (de) 1992-12-03
IE882195L (en) 1989-02-06
GB8718619D0 (en) 1987-09-09
EG18652A (en) 1993-10-30
NO883500D0 (no) 1988-08-05
FI88713C (fi) 1993-06-28
DK435688A (da) 1989-02-07
EP0304190B1 (en) 1992-07-08
PL158324B1 (en) 1992-08-31
DK435688D0 (da) 1988-08-04
IL87201A (en) 1995-08-31
DE3872620D1 (de) 1992-08-13
MY103595A (en) 1993-08-28
JPS6479146A (en) 1989-03-24
AU620550B2 (en) 1992-02-20

Similar Documents

Publication Publication Date Title
ES2042753T3 (es) Procedimiento para la preparacion de derivados de nitrometano.
AR015470A1 (es) Acido beta-arilo-alfa-alquilcarboxilico, su uso para la manufactura de un medicamento, procedimientos para su preparacion, composiciones farmaceuticas quelos contienen, compuestos intermediarios y procedimiento para su preparacion
ES2051719T3 (es) Un procedimiento para producir un compuesto de benzoilurea.
PT81637B (pt) Processo para a preparacao de novos compostos de indol acidicos e de composicoes farmaceuticas que os contem
AR039127A1 (es) Compuesto de quinolina, procedimiento para su preparacion, composicion farmaceutica que lo comprende y uso del mismo para la fabricacion de un medicamento
ES2058527T3 (es) Derivados de pirimidina condensados procedimiento y compuestos intermedios para su preparacion y composiciones farmaceuticas que los contienen.
DE3761307D1 (de) Herstellung von fibraten.
HUP0204143A2 (en) Tricyclic 1-benzylpyrazoles-3-carboxylic acid derivatives, preparation of the compounds, their use and pharmaceutical compositions containing them
ES2054304T3 (es) Feniletanolaminometiltetralinas, procedimiento para su preparacion y composiciones farmaceuticas que las contienen.
ES2177940T3 (es) Nuevos derivados de arilglicinamidas, procedimiento para su preparacion y composiciones farmaceuticas que contienen estos compuestos.
BR9307580A (pt) Compostos processo para a preparação dos mesmos composições farmacêuticas uso de um composto e processo de tratamento de um mamífero que inclui o ser humano
ES530311A0 (es) Procedimiento para preparar derivados de prolina disustituidos.
PT93160A (pt) Processo para a preparacao de benzenossulfonamidas e de composicoes farmaceuticas que as contem
DZ1468A1 (fr) Composés nouveaux.
PT94957A (pt) Processo para preparacao de composicoes farmaceuticas para tratamento da hipertrofia e hiperplasia cardiais e vasculares compreendendo um inibidor do enzima de conversao da angiotensina
AR001813A1 (es) Derivados de cromona procedimiento para prepararlos y las composiciones farmacéutica que los contienen
ES545004A0 (es) Un procedimiento para producir un acetileno.
ES2061478T3 (es) Derivados de teofilin-metil-ditiolano y teofilin-metil-ditianilo, un metodo para su preparacion, y composiciones farmaceuticas que los contienen.
ES2057441T3 (es) Derivados de piridina, procesos para su preparacion y composiciones farmaceuticas de los mismos.
GT199900047A (es) Procedimiento para alquilar sulfonamidas impedidas estèricamente.
DK333380A (da) Fremgangsmaade til fremstilling af 3-amino-1-benzoxepin-derivater eller syreadditionssalte deraf
PT84161B (pt) Processo para a preparacao de derivados de 3-acilaminometil-imidazo-{1,2-a}-piridinas e de composicoes farmaceuticas que os contem
PT989994E (pt) Derivados de estreptograminas, a sua preparacao e as composicoes que os contem
PT83929B (pt) Processo de preparacao de 3-benzazepinas substituidas por sulfinilo e sulfonilo e das composicoes farmaceuticas que as contem
DK222087D0 (da) Aeny fremgangsmaade til fremstilling af kemiske for-bindelserae

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 304190

Country of ref document: ES