PT83929B - Processo de preparacao de 3-benzazepinas substituidas por sulfinilo e sulfonilo e das composicoes farmaceuticas que as contem - Google Patents

Processo de preparacao de 3-benzazepinas substituidas por sulfinilo e sulfonilo e das composicoes farmaceuticas que as contem

Info

Publication number
PT83929B
PT83929B PT83929A PT8392986A PT83929B PT 83929 B PT83929 B PT 83929B PT 83929 A PT83929 A PT 83929A PT 8392986 A PT8392986 A PT 8392986A PT 83929 B PT83929 B PT 83929B
Authority
PT
Portugal
Prior art keywords
c6alkyl
pharmaceutical compositions
hydrogen
benzazepines
sulfinyl
Prior art date
Application number
PT83929A
Other languages
English (en)
Other versions
PT83929A (en
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of PT83929A publication Critical patent/PT83929A/pt
Publication of PT83929B publication Critical patent/PT83929B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/06Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
    • C07D233/08Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms
    • C07D233/12Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D233/16Radicals substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Thermal Transfer Or Thermal Recording In General (AREA)
  • Hydrogenated Pyridines (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
PT83929A 1985-12-20 1986-12-15 Processo de preparacao de 3-benzazepinas substituidas por sulfinilo e sulfonilo e das composicoes farmaceuticas que as contem PT83929B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/811,789 US4659706A (en) 1985-12-20 1985-12-20 Sulfinyl and sulfonyl substituted 3-benzazepines

Publications (2)

Publication Number Publication Date
PT83929A PT83929A (en) 1987-01-01
PT83929B true PT83929B (pt) 1989-05-12

Family

ID=25207582

Family Applications (1)

Application Number Title Priority Date Filing Date
PT83929A PT83929B (pt) 1985-12-20 1986-12-15 Processo de preparacao de 3-benzazepinas substituidas por sulfinilo e sulfonilo e das composicoes farmaceuticas que as contem

Country Status (17)

Country Link
US (1) US4659706A (pt)
EP (1) EP0229510B1 (pt)
JP (1) JPS62158255A (pt)
KR (1) KR870006007A (pt)
CN (1) CN86108627A (pt)
AT (1) ATE53385T1 (pt)
AU (1) AU589240B2 (pt)
CA (1) CA1263384A (pt)
DE (1) DE3671746D1 (pt)
DK (1) DK610686A (pt)
FI (1) FI865220A (pt)
HU (1) HUT43826A (pt)
IL (1) IL81006A0 (pt)
NO (1) NO865203L (pt)
PH (1) PH22358A (pt)
PT (1) PT83929B (pt)
ZA (1) ZA869501B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0285287A3 (en) * 1987-03-23 1990-08-16 Smithkline Beecham Corporation 3-benzazepine compounds for use in treating gastrointestinal motility disorders
PT100602A (pt) * 1991-06-21 1993-09-30 Smithkline Beecham Plc Uso de derivados de tetra-hidrobenzazepinas, derivados de tetra-hidrobenzazepinas,sua preparacao e composicoes farmaceuticas que os contem
EP1112106B1 (en) 1998-09-18 2005-11-23 Alcon Manufacturing Ltd. Serotonergic 5ht2 agonists for treating glaucoma
CA2347095A1 (en) * 1998-10-16 2000-04-27 Takeda Chemical Industries, Ltd. Nitrogen-containing condensed heterocyclic derivatives, their production and agent
KR100480782B1 (ko) * 2002-10-26 2005-04-07 삼성에스디아이 주식회사 연료전지 단위체, 그 제조방법 및 상기 연료전지 단위체를채용한 연료전지
US20060073172A1 (en) * 2004-10-01 2006-04-06 Schneider L W Stabilized ophthalmic solution for the treatment of glaucoma and lowering intraocular pressure

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3483185A (en) * 1966-08-16 1969-12-09 American Home Prod N-substituted 2,3,4,5-tetrahydro-1h-3-benzazepines
CA974989A (en) * 1968-03-11 1975-09-23 Wallace And Tiernan Inc. Process for preparing 1,2,4,5-tetrahydro-3h,3-benzazepines and products obtained thereby
DE1921737A1 (de) * 1969-04-29 1970-11-12 Bayer Ag Heterocyclische Acylreste enthaltende Sulfonylharnstoffe und Sulfonylsemicarbazide mit antidiabetischer Wirkung
US3671519A (en) * 1969-07-14 1972-06-20 American Home Prod N-substituted 2,3,4,5,-tetrahydro-1h-3-benzazepines
US3725388A (en) * 1970-06-25 1973-04-03 Boehringer Sohn Ingelheim N-acyl-7-(n{41 -cycloalkyl-ureido-n{40 -sulfonyl)-isoquinolines and -benzazepines and alkali metal salts thereof
CH593263A5 (pt) * 1974-02-22 1977-11-30 Hoffmann La Roche
US4206210A (en) * 1977-01-19 1980-06-03 Smithkline Corporation Alkylthio-7,8-dihdroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines having dopaminergic activity
US4265890A (en) * 1978-07-07 1981-05-05 Smithkline Corporation 6-Phenyl thio- and 6-cyclohexyl thio-2,3,4,5-tetrahydro-1H-3-benzazepines
US4469634A (en) * 1982-07-29 1984-09-04 Smithkline Beckman Corporation Allyloxy- and allylthio-2,3,4,5-tetrahydro-1H-3-benzazepines

Also Published As

Publication number Publication date
CN86108627A (zh) 1987-07-22
JPS62158255A (ja) 1987-07-14
IL81006A0 (en) 1987-03-31
HUT43826A (en) 1987-12-28
DK610686A (da) 1987-06-21
ZA869501B (en) 1987-08-26
CA1263384A (en) 1989-11-28
KR870006007A (ko) 1987-07-08
ATE53385T1 (de) 1990-06-15
AU6677986A (en) 1987-06-25
NO865203D0 (no) 1986-12-19
FI865220A0 (fi) 1986-12-19
EP0229510A1 (en) 1987-07-22
FI865220A (fi) 1987-06-21
EP0229510B1 (en) 1990-06-06
DK610686D0 (da) 1986-12-17
PH22358A (en) 1988-08-12
US4659706A (en) 1987-04-21
PT83929A (en) 1987-01-01
NO865203L (no) 1987-06-22
DE3671746D1 (de) 1990-07-12
AU589240B2 (en) 1989-10-05

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Effective date: 19930430