HUT43826A - Process for producing 3-benzazepine derivatives substituted with sulfinyl- and sulfonyl-groups and pharmaceutical compositions containing them - Google Patents

Process for producing 3-benzazepine derivatives substituted with sulfinyl- and sulfonyl-groups and pharmaceutical compositions containing them

Info

Publication number
HUT43826A
HUT43826A HU865351A HU535186A HUT43826A HU T43826 A HUT43826 A HU T43826A HU 865351 A HU865351 A HU 865351A HU 535186 A HU535186 A HU 535186A HU T43826 A HUT43826 A HU T43826A
Authority
HU
Hungary
Prior art keywords
c6alkyl
pharmaceutical compositions
sulfinyl
sulfonyl
groups
Prior art date
Application number
HU865351A
Other languages
English (en)
Inventor
William E Bondinell
Iii Herbert S Ormsbee
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of HUT43826A publication Critical patent/HUT43826A/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/06Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
    • C07D233/08Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms
    • C07D233/12Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D233/16Radicals substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thermal Transfer Or Thermal Recording In General (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Hydrogenated Pyridines (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
HU865351A 1985-12-20 1986-12-19 Process for producing 3-benzazepine derivatives substituted with sulfinyl- and sulfonyl-groups and pharmaceutical compositions containing them HUT43826A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/811,789 US4659706A (en) 1985-12-20 1985-12-20 Sulfinyl and sulfonyl substituted 3-benzazepines

Publications (1)

Publication Number Publication Date
HUT43826A true HUT43826A (en) 1987-12-28

Family

ID=25207582

Family Applications (1)

Application Number Title Priority Date Filing Date
HU865351A HUT43826A (en) 1985-12-20 1986-12-19 Process for producing 3-benzazepine derivatives substituted with sulfinyl- and sulfonyl-groups and pharmaceutical compositions containing them

Country Status (17)

Country Link
US (1) US4659706A (hu)
EP (1) EP0229510B1 (hu)
JP (1) JPS62158255A (hu)
KR (1) KR870006007A (hu)
CN (1) CN86108627A (hu)
AT (1) ATE53385T1 (hu)
AU (1) AU589240B2 (hu)
CA (1) CA1263384A (hu)
DE (1) DE3671746D1 (hu)
DK (1) DK610686A (hu)
FI (1) FI865220A (hu)
HU (1) HUT43826A (hu)
IL (1) IL81006A0 (hu)
NO (1) NO865203L (hu)
PH (1) PH22358A (hu)
PT (1) PT83929B (hu)
ZA (1) ZA869501B (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0285287A3 (en) * 1987-03-23 1990-08-16 Smithkline Beecham Corporation 3-benzazepine compounds for use in treating gastrointestinal motility disorders
KR940701258A (ko) * 1991-06-21 1994-05-28 피터 죤 기딩즈 문맥압 항진증 및 편두통의 치료를 위한 테트라하이드로벤즈아제핀 유도체의 용도
CA2344150A1 (en) 1998-09-18 2000-03-30 Alcon Laboratories, Inc. Serotonergic 5ht2 agonists for treating glaucoma
EP1122252A4 (en) * 1998-10-16 2002-06-26 Takeda Chemical Industries Ltd CONDENSED HEREROCYCLIC NITROGEN COMPOUNDS; MANUFACTURING PROCESS AND AGENTS CONTAINING THEM
KR100480782B1 (ko) * 2002-10-26 2005-04-07 삼성에스디아이 주식회사 연료전지 단위체, 그 제조방법 및 상기 연료전지 단위체를채용한 연료전지
US20060073172A1 (en) * 2004-10-01 2006-04-06 Schneider L W Stabilized ophthalmic solution for the treatment of glaucoma and lowering intraocular pressure

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3483185A (en) * 1966-08-16 1969-12-09 American Home Prod N-substituted 2,3,4,5-tetrahydro-1h-3-benzazepines
CA974989A (en) * 1968-03-11 1975-09-23 Wallace And Tiernan Inc. Process for preparing 1,2,4,5-tetrahydro-3h,3-benzazepines and products obtained thereby
DE1921737A1 (de) * 1969-04-29 1970-11-12 Bayer Ag Heterocyclische Acylreste enthaltende Sulfonylharnstoffe und Sulfonylsemicarbazide mit antidiabetischer Wirkung
US3671519A (en) * 1969-07-14 1972-06-20 American Home Prod N-substituted 2,3,4,5,-tetrahydro-1h-3-benzazepines
US3725388A (en) * 1970-06-25 1973-04-03 Boehringer Sohn Ingelheim N-acyl-7-(n{41 -cycloalkyl-ureido-n{40 -sulfonyl)-isoquinolines and -benzazepines and alkali metal salts thereof
CH593263A5 (hu) * 1974-02-22 1977-11-30 Hoffmann La Roche
US4206210A (en) * 1977-01-19 1980-06-03 Smithkline Corporation Alkylthio-7,8-dihdroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines having dopaminergic activity
US4265890A (en) * 1978-07-07 1981-05-05 Smithkline Corporation 6-Phenyl thio- and 6-cyclohexyl thio-2,3,4,5-tetrahydro-1H-3-benzazepines
US4469634A (en) * 1982-07-29 1984-09-04 Smithkline Beckman Corporation Allyloxy- and allylthio-2,3,4,5-tetrahydro-1H-3-benzazepines

Also Published As

Publication number Publication date
AU589240B2 (en) 1989-10-05
KR870006007A (ko) 1987-07-08
IL81006A0 (en) 1987-03-31
CN86108627A (zh) 1987-07-22
JPS62158255A (ja) 1987-07-14
PH22358A (en) 1988-08-12
PT83929A (en) 1987-01-01
EP0229510A1 (en) 1987-07-22
EP0229510B1 (en) 1990-06-06
ATE53385T1 (de) 1990-06-15
DK610686D0 (da) 1986-12-17
FI865220A0 (fi) 1986-12-19
NO865203D0 (no) 1986-12-19
NO865203L (no) 1987-06-22
DE3671746D1 (de) 1990-07-12
PT83929B (pt) 1989-05-12
ZA869501B (en) 1987-08-26
FI865220A (fi) 1987-06-21
AU6677986A (en) 1987-06-25
US4659706A (en) 1987-04-21
DK610686A (da) 1987-06-21
CA1263384A (en) 1989-11-28

Similar Documents

Publication Publication Date Title
HUT50322A (en) Process for producing substituted quinazoline derivatives and pharmaceutical compositions comprising such compounds
YU48765B (en) Amides isoxasole - 4 - carbon acid and amides of hidroxy-alkiliden ciano vinegar acid and the procedure for obtaining pharmaceutic preparations containing those compounds
HUT43826A (en) Process for producing 3-benzazepine derivatives substituted with sulfinyl- and sulfonyl-groups and pharmaceutical compositions containing them
KR880009975A (ko) 화합물
HU206669B (en) Process for producing new salts of diphenyl-acetic acid and aryl-propanol-amines
ZA898498B (en) 1,2,3,4-tetrahydro-1,9-acridinediamines,a process for their preparation and their use as medicaments
AU586724B2 (en) 1-phenyl-3-benzazepines
ZA903944B (en) Pyrrolidone derivatives the process for their preparation and the pharmaceutical compositions containing them
HUT71127A (en) 2,3,4,5-tetrahydro-1h-3-benzodiazepines and pharmaceutically acceptable acid additional salts thereof, pharmaceutical compositions containing them and process for their preparation
EP0276805A3 (en) Substituted 3-phenyl-7h-thiazoloû3,2-b¨û1,2,4¨triazin-7-ones, processes for their preparation, medicaments containing them and their use as well as some of the intermediates obtained during the preparation of said compounds
AU562271B2 (en) Pharmaceutical composition of corazepam and diphenhydramine
HUT54682A (en) Process for producing 13-bromine- and 13,14-dibromine-ergoline derivatives and pharmaceutical preparatives containing these compounds
DE3469358D1 (en) Novel 3-(4'-aminobutylamino)-propylamino-bleomycin derivatives, a process for their preparation and their use as medicaments
GR850484B (hu)