ES2040853T3 - Preparacion de acidos oxoftalazinilaceticos con cadenas laterales de benzotiazol u otros heterociclos. - Google Patents
Preparacion de acidos oxoftalazinilaceticos con cadenas laterales de benzotiazol u otros heterociclos.Info
- Publication number
- ES2040853T3 ES2040853T3 ES198888305180T ES88305180T ES2040853T3 ES 2040853 T3 ES2040853 T3 ES 2040853T3 ES 198888305180 T ES198888305180 T ES 198888305180T ES 88305180 T ES88305180 T ES 88305180T ES 2040853 T3 ES2040853 T3 ES 2040853T3
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- side chains
- acids
- oxoftalazinylacetic
- heterocicles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/89—Benzo [c] furans; Hydrogenated benzo [c] furans with two oxygen atoms directly attached in positions 1 and 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Abstract
UN PROCESO PARA LA PREPARACION DE ACIDOS OXOFTALAZINIL ACETICOS CON BENZOTIAZOL U OTRAS CADENAS LATERALES HETEROCICLICAS QUE COMPRENDE LA REACCION DE ESTER DEL ACIDO OXOFTALIZINIL ACETICO CON UN DERIVADO DE ANILINA. TAMBIEN SE PRSENTAN PROCESOS PARA LA PREPARACION DE TALES ESTERES DE OXOFTALIZINILO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5989987A | 1987-06-09 | 1987-06-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2040853T3 true ES2040853T3 (es) | 1993-11-01 |
Family
ID=22026001
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES198888305180T Expired - Lifetime ES2040853T3 (es) | 1987-06-09 | 1988-06-07 | Preparacion de acidos oxoftalazinilaceticos con cadenas laterales de benzotiazol u otros heterociclos. |
Country Status (26)
Country | Link |
---|---|
EP (1) | EP0295051B1 (es) |
JP (1) | JPH0676391B2 (es) |
KR (1) | KR900004698B1 (es) |
CN (1) | CN1024347C (es) |
AT (1) | ATE90347T1 (es) |
AU (1) | AU593742B2 (es) |
CA (1) | CA1321791C (es) |
CS (1) | CS274628B2 (es) |
DD (3) | DD280323A5 (es) |
DE (1) | DE3881583T2 (es) |
DK (1) | DK309988A (es) |
EG (1) | EG18613A (es) |
ES (1) | ES2040853T3 (es) |
FI (1) | FI93835C (es) |
HU (1) | HU205108B (es) |
IE (1) | IE61499B1 (es) |
IL (1) | IL86660A0 (es) |
MY (1) | MY103573A (es) |
NO (1) | NO176317C (es) |
NZ (1) | NZ224937A (es) |
PH (1) | PH25928A (es) |
PL (1) | PL157690B1 (es) |
PT (1) | PT87669B (es) |
SU (1) | SU1678208A3 (es) |
YU (1) | YU46696B (es) |
ZA (1) | ZA884075B (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0322153A3 (en) * | 1987-12-21 | 1990-08-16 | Pfizer Inc. | Heterocyclic oxophtalazinyl acetic acids |
WO1989006651A1 (en) * | 1988-01-19 | 1989-07-27 | Pfizer Inc. | 1h-indazole-3-acetic acids as aldose reductase inhibitors |
US4904782A (en) * | 1988-02-29 | 1990-02-27 | Pfizer Inc. | Process for the production of phthalazineacetic acid ester derivatives and a novel intermediate |
US4954629A (en) * | 1989-05-11 | 1990-09-04 | Pfizer Inc. | Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof |
FR2647676A1 (fr) * | 1989-06-05 | 1990-12-07 | Union Pharma Scient Appl | Nouveaux derives de pyridazinone, leurs procedes de preparation, medicaments les contenant, utiles notamment comme inhibiteurs de l'aldose reductase |
US5304557A (en) * | 1989-12-15 | 1994-04-19 | Pfizer Inc. | Substituted oxoophthalazinyl acetic acids and analogs thereof |
US5064830A (en) * | 1990-08-02 | 1991-11-12 | Pfizer Inc. | Lowering of blood uric acid levels |
WO1992003432A1 (en) * | 1990-08-28 | 1992-03-05 | Pfizer Inc. | 3-(5-trifluoromethylbenzothiazol-2-ylmethyl)-4-oxo-3h-phythalazin-1-ylacetic acid monohydrate |
CA2107104A1 (en) * | 1991-03-28 | 1992-09-29 | Banavara L. Mylari | Pyridazinone acetic acids as aldose reductase inhibitors |
FR2682108B1 (fr) * | 1991-10-07 | 1994-01-07 | Lipha | Acide 3,4-dihydro-4-oxo-3(prop-2-enyl)-1-phtalazineacetiques et derives, leurs preparations et medicaments les contenant. |
DE69405193T2 (de) * | 1993-10-06 | 1998-01-02 | Sumika Fine Chemicals Co Ltd | Verfahren zur Herstellung von Alkyl-3-phthalidylidenacetat |
US5700819A (en) * | 1994-11-29 | 1997-12-23 | Grelan Pharmaceutical Co., Ltd. | 2-substituted benzothiazole derivatives and prophylactic and therapeutic agents for the treatment of diabetic complications |
IL124236A (en) * | 1997-05-05 | 2003-01-12 | Pfizer | Pharmaceutical composition for treating or reversing diabetic cardiomyopathy comprising aldose reductase inhibitor |
EP0982306A3 (en) * | 1998-08-21 | 2000-07-05 | Pfizer Products Inc. | Polymorph of zopolrestat monohydrate |
SG82702A1 (en) * | 1999-09-28 | 2001-08-21 | Ebauchesfabrik Eta Ag | Timepiece including a movement mounted in a casing ring |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE47592B1 (en) * | 1977-12-29 | 1984-05-02 | Ici Ltd | Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture |
JPS5931509B2 (ja) * | 1979-06-06 | 1984-08-02 | 昭和電工株式会社 | 3−ヒドロキシ−3−メチルフタリド又はその核置換体の製造法 |
ES2032749T3 (es) * | 1985-11-07 | 1993-03-01 | Pfizer Inc. | Acidos oxoftalazinil-aceticos heterociclicos. |
-
1988
- 1988-06-02 JP JP63136601A patent/JPH0676391B2/ja not_active Expired - Lifetime
- 1988-06-06 PH PH37013A patent/PH25928A/en unknown
- 1988-06-06 MY MYPI88000606A patent/MY103573A/en unknown
- 1988-06-07 DD DD88326850A patent/DD280323A5/de not_active IP Right Cessation
- 1988-06-07 EP EP88305180A patent/EP0295051B1/en not_active Expired - Lifetime
- 1988-06-07 AT AT88305180T patent/ATE90347T1/de not_active IP Right Cessation
- 1988-06-07 ES ES198888305180T patent/ES2040853T3/es not_active Expired - Lifetime
- 1988-06-07 PL PL1988272899A patent/PL157690B1/pl unknown
- 1988-06-07 DD DD88326849A patent/DD280320A5/de not_active IP Right Cessation
- 1988-06-07 DE DE8888305180T patent/DE3881583T2/de not_active Expired - Fee Related
- 1988-06-07 CA CA000568775A patent/CA1321791C/en not_active Expired - Fee Related
- 1988-06-07 DD DD88316492A patent/DD281600A5/de not_active IP Right Cessation
- 1988-06-07 CS CS392488A patent/CS274628B2/cs not_active IP Right Cessation
- 1988-06-08 HU HU882971A patent/HU205108B/hu not_active IP Right Cessation
- 1988-06-08 PT PT87669A patent/PT87669B/pt not_active IP Right Cessation
- 1988-06-08 IL IL86660A patent/IL86660A0/xx not_active IP Right Cessation
- 1988-06-08 SU SU884355901A patent/SU1678208A3/ru active
- 1988-06-08 NO NO882516A patent/NO176317C/no not_active IP Right Cessation
- 1988-06-08 AU AU17491/88A patent/AU593742B2/en not_active Ceased
- 1988-06-08 CN CN88103507A patent/CN1024347C/zh not_active Expired - Fee Related
- 1988-06-08 ZA ZA884075A patent/ZA884075B/xx unknown
- 1988-06-08 KR KR1019880006855A patent/KR900004698B1/ko not_active IP Right Cessation
- 1988-06-08 FI FI882722A patent/FI93835C/fi not_active IP Right Cessation
- 1988-06-08 NZ NZ224937A patent/NZ224937A/xx unknown
- 1988-06-08 IE IE171688A patent/IE61499B1/en unknown
- 1988-06-08 DK DK309988A patent/DK309988A/da not_active Application Discontinuation
- 1988-06-08 YU YU111188A patent/YU46696B/sh unknown
- 1988-06-09 EG EG320/88A patent/EG18613A/xx active
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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