ES2038733T3 - Procedimiento para preparar una solucion inyectable de la sal de acido tioctico con trometanol y/o aminoacidos basicos. - Google Patents

Procedimiento para preparar una solucion inyectable de la sal de acido tioctico con trometanol y/o aminoacidos basicos.

Info

Publication number
ES2038733T3
ES2038733T3 ES198888119790T ES88119790T ES2038733T3 ES 2038733 T3 ES2038733 T3 ES 2038733T3 ES 198888119790 T ES198888119790 T ES 198888119790T ES 88119790 T ES88119790 T ES 88119790T ES 2038733 T3 ES2038733 T3 ES 2038733T3
Authority
ES
Spain
Prior art keywords
amino acids
acid salt
thromethanol
basic amino
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888119790T
Other languages
English (en)
Spanish (es)
Inventor
Helmut Dr. Hettche
Reinhard Dr. Muckenschnabel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asta Medica GmbH
Original Assignee
Asta Medica GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6341895&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2038733(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Asta Medica GmbH filed Critical Asta Medica GmbH
Application granted granted Critical
Publication of ES2038733T3 publication Critical patent/ES2038733T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES198888119790T 1987-12-04 1988-11-28 Procedimiento para preparar una solucion inyectable de la sal de acido tioctico con trometanol y/o aminoacidos basicos. Expired - Lifetime ES2038733T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3741152 1987-12-04

Publications (1)

Publication Number Publication Date
ES2038733T3 true ES2038733T3 (es) 1993-08-01

Family

ID=6341895

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888119790T Expired - Lifetime ES2038733T3 (es) 1987-12-04 1988-11-28 Procedimiento para preparar una solucion inyectable de la sal de acido tioctico con trometanol y/o aminoacidos basicos.

Country Status (7)

Country Link
EP (1) EP0318891B1 (enExample)
AT (1) ATE70974T1 (enExample)
DE (1) DE3867445D1 (enExample)
ES (1) ES2038733T3 (enExample)
GR (1) GR3003517T3 (enExample)
IE (1) IE60877B1 (enExample)
PT (1) PT89144B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2063713A1 (es) * 1992-10-15 1995-01-01 Asta Medica Ag Ampolla y solucion para infusion de acido tioctico en forma de las sales solubles en agua del acido tioctico.
ES2125800A1 (es) * 1995-04-25 1999-03-01 Asta Medica Ag Conjunto de infusion final.

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0382066A3 (de) * 1989-02-09 1992-01-08 ASTA Medica Aktiengesellschaft Verwendung von Dihydroliponsäure als Analgetikum, Antiphlogistikum und/oder Zytoprotektivum
EP0812590A3 (de) * 1989-11-09 1999-06-09 ASTA Medica Aktiengesellschaft Verwendung von R-Alpha-Liponsäure zur Zytoprotektion
BE1003834A5 (fr) * 1989-11-09 1992-06-23 Asta Medica Ag Medicaments qui contiennent, comme substance active, des acides carboxyliques contenant du soufre, ainsi que leur utilisation pour lutter contre des retrovirus.
DE59209162D1 (de) * 1991-07-05 1998-03-05 Asta Medica Ag Verwendung von Schwefel enthaltenden Carbonsäuren zur Bekämpfung von pathophysiologisch bedingten Erregungsstörungen
EP1023284B1 (en) * 1996-07-05 2005-11-23 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Anti-viral pharmaceutical compositions containing saturated 1,2-dithiaheterocyclic compounds
DE19806354B4 (de) * 1998-02-10 2004-09-16 Bdd Group Holding Ag Verwendung von α-Liponsäure oder deren physiologisch verträgliche Salze zur Behandlung von LDL-Hypercholesterinämie
DE10159245A1 (de) * 2001-12-03 2003-06-18 Degussa Stabile, saure, wässrige Lösung enthaltend alpha-Liponsäure(-Derivate), Verfahren zu deren Herstellung sowie ihre Verwendung
CN1853626B (zh) * 2005-04-29 2010-10-06 上海医药工业研究院 一种供注射用的硫辛酸冻干制剂
ATE418976T1 (de) 2005-08-04 2009-01-15 Extarma Ag Flüssige zusammensetzung enthaltend arginine und alpha-liponsäure zur verbesserung der sexuellen funktion
IT1399923B1 (it) 2010-05-11 2013-05-09 Cbb Net S A Procedimento di preparazione di sali dell'acido (r) alfa-lipoico loro formulazione ed uso nelle composizioni farmaceutiche in forma di compresse che li contengono
EP2389931A1 (en) * 2010-05-21 2011-11-30 Raw Materials Internatinal LLC Pharmaceutical aqueous compositions comprising lipoic acid as an antioxidant
ITMI20111452A1 (it) * 2011-07-29 2013-01-30 Istituto Biochimico Naz Sav Io Srl Soluzione basica di acido alfa-lipoico e suoi usi
IT202000009577A1 (it) 2020-04-30 2021-10-30 Fatro Spa Formulazioni iniettabili di acido lipoico per il trattamento dello stress ossidativo e delle alterazioni metaboliche

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1056784B (de) * 1956-05-24 1959-05-06 Istituto Sieroterapico Italian Verfahren zur Herstellung von stabilen Injektionsloesungen der 6,8-Thioctsaeure
DE1047991B (de) * 1957-11-20 1958-12-31 Nordmark Werke Gmbh Verfahren zur Herstellung chemisch stabiler, untoxischer, steriler Injektionsloesungen von Thioctsaeure
DE1095991B (de) * 1959-05-09 1960-12-29 Chemiewerk Homburg Zweignieder Verfahren zur Herstellung einer stabilen und injizierbaren 1,2-Dithia-cyclopentan-3-valeriansaeure enthaltenden Loesung
FR4630M (enExample) * 1965-06-09 1966-11-28
ES323195A1 (es) * 1966-02-17 1966-12-01 Ferrer Labor Procedimiento de obtenciën de compuestos de acciën antiacidëtica
DE1617740B1 (de) * 1967-09-25 1971-11-04 Pfrimmer & Co J Verfahren zum Stabilisieren von Alfa-Liponsäure
ZA716628B (en) * 1970-10-15 1972-06-28 Richardson Merrell Spa Composition and method for treatment of hepatic disease and mental fatigue
DE2629845A1 (de) * 1976-07-02 1978-01-05 Geb Graze Erika Graze Infusions- bzw. injektionsloesungen bzw. waessrige konzentrate zu deren bereitung zur therapeutischen restituion des zellulaeren energiestoffwechsels und der koerpereigenen regelfunktion
GB1504767A (en) * 1976-08-23 1978-03-22 Beecham Group Ltd Antibiotic compositions
DE3217315C2 (de) * 1982-05-08 1986-05-22 Gödecke AG, 1000 Berlin Arzneimittelzubereitungen mit einem Gehalt an Oxicam-Derivaten

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2063713A1 (es) * 1992-10-15 1995-01-01 Asta Medica Ag Ampolla y solucion para infusion de acido tioctico en forma de las sales solubles en agua del acido tioctico.
ES2125800A1 (es) * 1995-04-25 1999-03-01 Asta Medica Ag Conjunto de infusion final.

Also Published As

Publication number Publication date
GR3003517T3 (enExample) 1993-03-16
DE3867445D1 (de) 1992-02-13
PT89144A (pt) 1989-12-29
PT89144B (pt) 1993-05-31
IE60877B1 (en) 1994-08-24
EP0318891B1 (de) 1992-01-02
ATE70974T1 (de) 1992-01-15
EP0318891A1 (de) 1989-06-07
IE883618L (en) 1989-06-04

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