PT89144A - Processo para a preparacao de uma solucao injectavel do sal do acido tioctico com trometamol e/ou com acidos aminados basicos - Google Patents

Processo para a preparacao de uma solucao injectavel do sal do acido tioctico com trometamol e/ou com acidos aminados basicos

Info

Publication number
PT89144A
PT89144A PT89144A PT8914488A PT89144A PT 89144 A PT89144 A PT 89144A PT 89144 A PT89144 A PT 89144A PT 8914488 A PT8914488 A PT 8914488A PT 89144 A PT89144 A PT 89144A
Authority
PT
Portugal
Prior art keywords
trometamol
amino acids
acid salt
thiocharid
basic amino
Prior art date
Application number
PT89144A
Other languages
English (en)
Other versions
PT89144B (pt
Inventor
Helmut Hettche
Reinhardt Muckenschnabel
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6341895&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT89144(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of PT89144A publication Critical patent/PT89144A/pt
Publication of PT89144B publication Critical patent/PT89144B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT89144A 1987-12-04 1988-12-02 Processo para a preparacao de uma solucao injectavel do sal do acido tioctico com trometamol e/ou com acidos aminados basicos PT89144B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3741152 1987-12-04

Publications (2)

Publication Number Publication Date
PT89144A true PT89144A (pt) 1989-12-29
PT89144B PT89144B (pt) 1993-05-31

Family

ID=6341895

Family Applications (1)

Application Number Title Priority Date Filing Date
PT89144A PT89144B (pt) 1987-12-04 1988-12-02 Processo para a preparacao de uma solucao injectavel do sal do acido tioctico com trometamol e/ou com acidos aminados basicos

Country Status (7)

Country Link
EP (1) EP0318891B1 (pt)
AT (1) ATE70974T1 (pt)
DE (1) DE3867445D1 (pt)
ES (1) ES2038733T3 (pt)
GR (1) GR3003517T3 (pt)
IE (1) IE60877B1 (pt)
PT (1) PT89144B (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5334612A (en) * 1988-11-09 1994-08-02 Asta Pharma Aktiengesellschaft Pharmaceutical compositions containing as active substance sulphur-containing carboxylic acids and their use in combating retroviruses
EP0382066A3 (de) * 1989-02-09 1992-01-08 ASTA Medica Aktiengesellschaft Verwendung von Dihydroliponsäure als Analgetikum, Antiphlogistikum und/oder Zytoprotektivum
DE4035442B4 (de) * 1989-11-09 2010-04-29 Evonik Degussa Gmbh Arzneimittel enthaltend als Wirkstoff R-α-Liponsäure
DK0530446T3 (da) * 1991-07-05 1998-09-23 Asta Medica Ag Anvendelse af svovlholdige carboxylsyrer til bekæmpelse af pathophysiologisk betingede exitationsforstyrrelser
DE9213914U1 (de) * 1992-10-15 1992-12-03 Asta Medica AG, 6000 Frankfurt Ampulle und Infusionslösung von Thioctsäure in Form der wasserlöslichen Salze der Thioctsäure
DE29506604U1 (de) * 1995-04-25 1995-06-14 Asta Medica Ag, 01277 Dresden Fertiginfusionsset
WO1998001440A2 (en) * 1996-07-05 1998-01-15 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Anti-viral pharmaceutical compositions containing saturated 1,2-dithiaheterocyclic compounds and uses thereof
DE19806354B4 (de) * 1998-02-10 2004-09-16 Bdd Group Holding Ag Verwendung von α-Liponsäure oder deren physiologisch verträgliche Salze zur Behandlung von LDL-Hypercholesterinämie
DE10159245A1 (de) * 2001-12-03 2003-06-18 Degussa Stabile, saure, wässrige Lösung enthaltend alpha-Liponsäure(-Derivate), Verfahren zu deren Herstellung sowie ihre Verwendung
CN1853626B (zh) * 2005-04-29 2010-10-06 上海医药工业研究院 一种供注射用的硫辛酸冻干制剂
EP1754478B1 (en) 2005-08-04 2008-12-31 Extarma AG Liquid Composition comprising arginine and alpha-lipoic acid and its use for improvement of sexual function
IT1399923B1 (it) 2010-05-11 2013-05-09 Cbb Net S A Procedimento di preparazione di sali dell'acido (r) alfa-lipoico loro formulazione ed uso nelle composizioni farmaceutiche in forma di compresse che li contengono
EP2389931A1 (en) * 2010-05-21 2011-11-30 Raw Materials Internatinal LLC Pharmaceutical aqueous compositions comprising lipoic acid as an antioxidant
ITMI20111452A1 (it) * 2011-07-29 2013-01-30 Istituto Biochimico Naz Sav Io Srl Soluzione basica di acido alfa-lipoico e suoi usi
IT202000009577A1 (it) 2020-04-30 2021-10-30 Fatro Spa Formulazioni iniettabili di acido lipoico per il trattamento dello stress ossidativo e delle alterazioni metaboliche

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1056784B (de) * 1956-05-24 1959-05-06 Istituto Sieroterapico Italian Verfahren zur Herstellung von stabilen Injektionsloesungen der 6,8-Thioctsaeure
DE1047991B (de) * 1957-11-20 1958-12-31 Nordmark Werke Gmbh Verfahren zur Herstellung chemisch stabiler, untoxischer, steriler Injektionsloesungen von Thioctsaeure
DE1095991B (de) * 1959-05-09 1960-12-29 Chemiewerk Homburg Zweignieder Verfahren zur Herstellung einer stabilen und injizierbaren 1,2-Dithia-cyclopentan-3-valeriansaeure enthaltenden Loesung
FR4630M (pt) * 1965-06-09 1966-11-28
ES323195A1 (es) * 1966-02-17 1966-12-01 Ferrer Labor Procedimiento de obtenciën de compuestos de acciën antiacidëtica
DE1617740B1 (de) * 1967-09-25 1971-11-04 Pfrimmer & Co J Verfahren zum Stabilisieren von Alfa-Liponsäure
ZA716628B (en) * 1970-10-15 1972-06-28 Richardson Merrell Spa Composition and method for treatment of hepatic disease and mental fatigue
DE2629845A1 (de) * 1976-07-02 1978-01-05 Geb Graze Erika Graze Infusions- bzw. injektionsloesungen bzw. waessrige konzentrate zu deren bereitung zur therapeutischen restituion des zellulaeren energiestoffwechsels und der koerpereigenen regelfunktion
GB1504767A (en) * 1976-08-23 1978-03-22 Beecham Group Ltd Antibiotic compositions
DE3217315C2 (de) * 1982-05-08 1986-05-22 Gödecke AG, 1000 Berlin Arzneimittelzubereitungen mit einem Gehalt an Oxicam-Derivaten

Also Published As

Publication number Publication date
EP0318891B1 (de) 1992-01-02
IE883618L (en) 1989-06-04
GR3003517T3 (pt) 1993-03-16
EP0318891A1 (de) 1989-06-07
ATE70974T1 (de) 1992-01-15
PT89144B (pt) 1993-05-31
IE60877B1 (en) 1994-08-24
ES2038733T3 (es) 1993-08-01
DE3867445D1 (de) 1992-02-13

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19921116

PC3A Transfer or assignment

Free format text: ASTA MEDICA HEALTH PRODUCTS GMBH & CO. KG DE

Effective date: 20020909

PD3A Change of proprietorship

Free format text: VIATRIS GMBH & CO. KG DE

Effective date: 20020909

Free format text: ASTA MEDICA GMBH DE

Effective date: 20020909

TE3A Change of address (patent)

Free format text: ASTA MEDICA AKTIENGESELLSCHAFT DE

Effective date: 20020909

TE3A Change of address (patent)

Free format text: VIATRIS GMBH & CO. KG DE

Effective date: 20050506

PD4A Change of proprietorship

Owner name: MEDA PHARMA GMBH & CO. KG, DE

Effective date: 20070604

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: MAXIMUM VALIDITY LIMIT REACHED

Effective date: 20081202