ES2037889T3 - Procedimiento para la microinyeccion en celulas vivas y dispositivo para la ejecucion del procedimiento. - Google Patents

Procedimiento para la microinyeccion en celulas vivas y dispositivo para la ejecucion del procedimiento.

Info

Publication number
ES2037889T3
ES2037889T3 ES198989102612T ES89102612T ES2037889T3 ES 2037889 T3 ES2037889 T3 ES 2037889T3 ES 198989102612 T ES198989102612 T ES 198989102612T ES 89102612 T ES89102612 T ES 89102612T ES 2037889 T3 ES2037889 T3 ES 2037889T3
Authority
ES
Spain
Prior art keywords
needle
cell
procedure
plane
stage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198989102612T
Other languages
English (en)
Inventor
Gunther Dipl.Bio.Dr. Bertholdt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eppendorf SE
Original Assignee
Eppendorf Netheler Hinz GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eppendorf Netheler Hinz GmbH filed Critical Eppendorf Netheler Hinz GmbH
Application granted granted Critical
Publication of ES2037889T3 publication Critical patent/ES2037889T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

POR LA MICROPROYECCION DE FLUIDOS O SUSPENSIONES DE SUSTANCIAS EN CELULAS VIVAS SE UNEN RELATIVAMENTE UNAS A OTRAS Y CON OTRAS SE FORMA SOLUBLE UNA MESA Y UNA CAMARA ALARGADA QUE SE DISPONE PARA ELLO. EL PROCEDIMIENTO Y EL DISPOSITIVO PARA LLEVAR A CABO ESTE PROCEDIMIENTO SE EXPLICA EN LA DESCRIPCION.
ES198989102612T 1988-03-15 1989-02-16 Procedimiento para la microinyeccion en celulas vivas y dispositivo para la ejecucion del procedimiento. Expired - Lifetime ES2037889T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3808531A DE3808531C1 (es) 1988-03-15 1988-03-15

Publications (1)

Publication Number Publication Date
ES2037889T3 true ES2037889T3 (es) 1993-07-01

Family

ID=6349731

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198989102612T Expired - Lifetime ES2037889T3 (es) 1988-03-15 1989-02-16 Procedimiento para la microinyeccion en celulas vivas y dispositivo para la ejecucion del procedimiento.

Country Status (6)

Country Link
US (1) US5114854A (es)
EP (1) EP0332864B1 (es)
JP (1) JPH0646943B2 (es)
AT (1) ATE85076T1 (es)
DE (1) DE3808531C1 (es)
ES (1) ES2037889T3 (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10136481A1 (de) * 2001-07-27 2003-02-20 Leica Microsystems Anordnung zum Mikromanipulieren von biologischen Objekten
US5413924A (en) * 1992-02-13 1995-05-09 Kosak; Kenneth M. Preparation of wax beads containing a reagent for release by heating
US5344610A (en) * 1993-02-03 1994-09-06 Eastman Kodak Company Aspirator probe with long pivot arm to minimize tip flick
DE4401076C2 (de) * 1994-01-15 1998-12-03 Eppendorf Geraetebau Netheler Vorrichtung zur Injektion von Flüssigkeiten in biologische Zellen
DE19629141A1 (de) * 1996-07-19 1998-04-16 Bayer Ag Verfahren und Vorrichtung zum Screening von Molekülen bezüglich ihres individuellen Bindungsverhaltens zu mindestens einem vorgegebenen Ligand
DE19714987C1 (de) * 1997-04-10 1998-09-24 Deutsches Krebsforsch Vorrichtung zur Isolation von Partikeln, insbesondere von Zellen
DE19721084A1 (de) * 1997-05-20 1998-11-26 Max Planck Gesellschaft Mikroinjektion
US5877008A (en) * 1997-07-22 1999-03-02 Lockheed Martin Energy Research Corporation Microinjector for blasocysts
JP4570776B2 (ja) 1997-12-12 2010-10-27 サミアン・コーポレーション 遺伝子輸送のための生物分解性の混合重合体ミセル
US6410057B1 (en) 1997-12-12 2002-06-25 Samyang Corporation Biodegradable mixed polymeric micelles for drug delivery
US6913934B2 (en) * 1998-08-13 2005-07-05 Symyx Technologies, Inc. Apparatus and methods for parallel processing of multiple reaction mixtures
US6759014B2 (en) * 2001-01-26 2004-07-06 Symyx Technologies, Inc. Apparatus and methods for parallel processing of multiple reaction mixtures
US7390648B1 (en) 1999-04-23 2008-06-24 Monica Palacios-Boyce Microelectromechanical devices useful for manipulating cells or embryos, kits thereof, method of making same, and methods of use thereof
JP3442357B2 (ja) * 2000-08-25 2003-09-02 株式会社日立製作所 両生類卵母細胞試料導入装置、両生類卵母細胞試料導入システム、両生類卵母細胞試料導入方法、両生類卵母細胞の製造方法、両生類卵母細胞及びそれを販売又は譲渡する方法、スクリーニング用のセンサーとして用いる方法、容器、及び解析方法
DE10136572B4 (de) * 2001-07-27 2005-11-17 Eppendorf Ag Vorrichtung zur optisch kontrollierten Mikromanipulation von biologischen Objekten
US20050254046A1 (en) * 2002-08-08 2005-11-17 National University Corporation Tokyo University O Single cell operation supporting robot
KR100475098B1 (ko) * 2002-11-12 2005-03-11 한국과학기술연구원 단일 셀 조작을 위한 바이오 자동 조작 장치
JP2007502114A (ja) * 2003-08-11 2007-02-08 コデクシス， インコーポレイテッド 改良されたグルコースデヒドロゲナーゼポリペプチドおよび関連ポリヌクレオチド
JP4504082B2 (ja) 2004-04-28 2010-07-14 富士通株式会社 液体注入装置
JP4456429B2 (ja) * 2004-07-27 2010-04-28 富士通株式会社 インジェクション装置
DE102004053596B4 (de) * 2004-11-05 2006-10-12 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren und Vorrichtungen zur Bearbeitung einzelner biologischer Zellen
JP4894199B2 (ja) * 2005-02-17 2012-03-14 富士通株式会社 物質注入装置
US20060246571A1 (en) * 2005-04-29 2006-11-02 Fujitsu Limited Apparatus and method for automatically producing substance-introduced particles
US7491669B2 (en) * 2006-02-07 2009-02-17 Crystal Clear Technologies, Inc. Adsorbent with multiple layers
JP2007166981A (ja) * 2005-12-22 2007-07-05 Fujitsu Ltd 注入装置及び方法
US8497119B1 (en) 2010-12-15 2013-07-30 Paul J. Taylor Method and device for performing micro-operations on a vesicular object
DE102011012993B3 (de) * 2011-03-04 2012-07-12 Otto-Von-Guericke-Universität Magdeburg Integriertes Greif- und Zuführsystem für Anwendungen in der Mikro- und Nanotechnik zur Manipulation von Mikro- und Nano-Objekten und Verfahren zur Durchführung der Manipulation
KR101387422B1 (ko) * 2012-06-13 2014-04-21 듀라케미 (주) 관의 내.외부 방식도장에 의해 결합된 패킹 일체형 관
GB2508906A (en) * 2012-12-14 2014-06-18 Life Science Methods Bv Frame element for sample injection with optical control means
WO2018080324A1 (en) 2016-10-31 2018-05-03 Mekonos Limited An array of needle manipulators for biological cell injection
US10702690B2 (en) 2017-02-03 2020-07-07 Infinitesimal Llc Electroporation system with micromanipulator and probe

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU675359A1 (en) * 1977-04-06 1979-07-25 Inst Biologicheskoi Fiz Method of obtaining sub-cell structures
JPS54158945A (en) * 1978-06-05 1979-12-15 Olympus Optical Co Ltd Micro-manipulator
DE3204040A1 (de) * 1982-02-05 1983-08-11 Europäisches Laboratorium für Molekularbiologie (EMBL), 6900 Heidelberg Verfahren und vorrichtung zur injektion von sehr kleinen probenmengen in zellen
JPS60501687A (ja) * 1983-06-30 1985-10-11 インステイテユ−ト　バイオヒミイ　イ　フイズイオロジイ　ミクロオルガニズモフ　アカデミイ　ナウク　エスエスエスア−ル 細胞の微小操作の実施方法および装置
JPS60118473A (ja) * 1983-11-29 1985-06-25 オリンパス光学工業株式会社 マイクロマニピユレ−タ
JPS60205411A (ja) * 1984-03-29 1985-10-17 Olympus Optical Co Ltd 倒立型顕微鏡
DE3718066A1 (de) * 1987-05-29 1988-12-08 Zeiss Carl Fa Verfahren zur mikroinjektion in zellen bzw. zum absaugen aus einzelnen zellen oder ganzer zellen aus zellkulturen

Also Published As

Publication number Publication date
ATE85076T1 (de) 1993-02-15
EP0332864B1 (de) 1993-01-27
US5114854A (en) 1992-05-19
JPH02119770A (ja) 1990-05-07
JPH0646943B2 (ja) 1994-06-22
EP0332864A2 (de) 1989-09-20
DE3808531C1 (es) 1989-07-13
EP0332864A3 (en) 1990-07-18

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