ES2032809T3 - Metodo para producir un compuesto de 7-bromo-b-carbolina. - Google Patents
Metodo para producir un compuesto de 7-bromo-b-carbolina.Info
- Publication number
- ES2032809T3 ES2032809T3 ES198787118864T ES87118864T ES2032809T3 ES 2032809 T3 ES2032809 T3 ES 2032809T3 ES 198787118864 T ES198787118864 T ES 198787118864T ES 87118864 T ES87118864 T ES 87118864T ES 2032809 T3 ES2032809 T3 ES 2032809T3
- Authority
- ES
- Spain
- Prior art keywords
- compound
- carboline
- bromine
- alkyl
- solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000002904 solvent Substances 0.000 abstract 3
- QIIQCUUHBSIRSM-UHFFFAOYSA-N 7-bromo-9h-pyrido[3,4-b]indole Chemical compound N1=CC=C2C3=CC=C(Br)C=C3NC2=C1 QIIQCUUHBSIRSM-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
UN COMPUESTO DE 7-BROMO-BETA-CARBOLINA DE FORMULA (I) DONDE R1 ES H O ALQUILO C1-C5 Y R2 ES ALQUILO C1-C5 O BENCILO. SE PRODUCE HACIENDO REACCIONAR UN COMPUESTO DE BETACARBOLINA DE FORMULA (II) DONDE R1 Y R2 SON COMO SE HAN DEFINIDO ANTERIORMENTE Y R3 ES H, ALQUILO C1-C5, ALCOXI C1-C5 O BENCILOXI, CON UN AGENTE BROMURANTE EN UN DISOLVENTE ORGANICO EN PRESENCIA DE UN ALCALI E HIDROLIZANDO DESPUES EL COMPUESTO PRECURSOR 7-BROMO-BETA-CARBOLINA DE FORMULA (III) EN UN DISOLVENTE EN PRESENCIA DE UN ACIDO MINERAL.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61310496A JP2527319B2 (ja) | 1986-12-25 | 1986-12-25 | 7―ブロモ―β―カルボリン誘導体の製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2032809T3 true ES2032809T3 (es) | 1993-03-01 |
Family
ID=18005925
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES198787118864T Expired - Lifetime ES2032809T3 (es) | 1986-12-25 | 1987-12-18 | Metodo para producir un compuesto de 7-bromo-b-carbolina. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4894457A (es) |
| EP (1) | EP0273321B1 (es) |
| JP (1) | JP2527319B2 (es) |
| DE (1) | DE3778517D1 (es) |
| ES (1) | ES2032809T3 (es) |
| HU (1) | HU200459B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5120543A (en) * | 1989-12-21 | 1992-06-09 | The United States Of America As Represented By The Secretary Of Agriculture | Molluscicidal β-carboline carboxylic acids and methods using the same |
| FR2796644B1 (fr) * | 1999-07-23 | 2001-09-07 | Adir | Nouveaux derives de beta-carboline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| US20040253891A1 (en) * | 2000-09-12 | 2004-12-16 | Schierenbeck Alan W. | Composite structure for protective garment |
| US20050137220A1 (en) * | 2003-07-23 | 2005-06-23 | Pharmacia Corporation | Beta-carboline compounds and analogues thereof as mitogen-activated protein kinase-activated protein kinase-2 inhibitors |
| JP4909183B2 (ja) * | 2007-06-01 | 2012-04-04 | 株式会社クボタ | 走行車両のフェンダ装置 |
| CN116253732B (zh) * | 2023-03-10 | 2024-04-12 | 石河子大学 | 一种N-N桥连靛红单元的β-咔啉衍生物及其制备方法、应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4220774A (en) * | 1978-10-26 | 1980-09-02 | Omnium Chimique | Vincadifformine synthesis process |
| FR2455044A1 (fr) * | 1979-04-26 | 1980-11-21 | Synthelabo | Pyrido-indoles et leur application en therapeutique |
| JPH07116194B2 (ja) * | 1986-08-25 | 1995-12-13 | 川研ファインケミカル株式会社 | ビンカジフオルミンの製造方法 |
-
1986
- 1986-12-25 JP JP61310496A patent/JP2527319B2/ja not_active Expired - Lifetime
-
1987
- 1987-12-18 ES ES198787118864T patent/ES2032809T3/es not_active Expired - Lifetime
- 1987-12-18 DE DE8787118864T patent/DE3778517D1/de not_active Expired - Lifetime
- 1987-12-18 EP EP87118864A patent/EP0273321B1/en not_active Expired - Lifetime
- 1987-12-21 US US07/135,392 patent/US4894457A/en not_active Expired - Fee Related
- 1987-12-23 HU HU875998A patent/HU200459B/hu not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US4894457A (en) | 1990-01-16 |
| JPS63162689A (ja) | 1988-07-06 |
| EP0273321B1 (en) | 1992-04-22 |
| HU200459B (en) | 1990-06-28 |
| EP0273321A1 (en) | 1988-07-06 |
| HUT46009A (en) | 1988-09-28 |
| JP2527319B2 (ja) | 1996-08-21 |
| DE3778517D1 (de) | 1992-05-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SE7710744L (sv) | Sett att framstella xylos genom enzymatisk hydrolys av xylaner | |
| DE3773089D1 (de) | Verfahren zur herstellung von thiazolidinedion-derivaten. | |
| ATE32709T1 (de) | Verfahren zur herstellung von ameisensaeure. | |
| ES2032809T3 (es) | Metodo para producir un compuesto de 7-bromo-b-carbolina. | |
| ATE18544T1 (de) | Verfahren zur veraetherung von hexitolen und anhydrohexitolen. | |
| ES2074431T3 (es) | Un procedimiento para la sintesis de amicacina. | |
| ES8503678A1 (es) | Proceso para producir un ester de benzoilpiperazina. | |
| ES8800215A1 (es) | Un procedimiento enantioselectivo para la preparacion de intermedios para los antibioticos de 1-b-metil-carbapenem | |
| ES8106126A1 (es) | Procedimiento para obtencion de intermediarios para la pro- duccion de penicilinas | |
| IL63464A (en) | Process for the production of 1,4:3,6-dianhydro-d-glucitol-5-nitrate and pharmaceutical compositions containing the compound produced by said process | |
| DE3877423D1 (de) | Verfahren zur herstellung von gamma-halogen-tiglinsaeurealkylestern sowie deren weiterverarbeitung zu 0,0-dialkyl-gamma-phosphono-tiglin-saeurealkylestern. | |
| ES8601949A1 (es) | Un procedimiento para preparar un derivado de rifanipicina | |
| ES2054231T3 (es) | Procedimiento para preparar oxido de estireno. | |
| ES2072296T3 (es) | Metodo para preparar 2-fenilbenzotriazoles. | |
| ATE63109T1 (de) | Verfahren zur herstellung von isothiazolonen. | |
| KR910007945A (ko) | 알킬 메틸-3-카브알콕시에틸포스피네이트의 제조방법 | |
| ES8705440A1 (es) | Un procedimiento para la produccion de 2h-imidazo-(1',2':1,2)-pirrolo-(3,4-b)-piridinas | |
| ES8607922A1 (es) | Procedimiento para preparar 9-oxo-15 a-hidroxi-16-fenoxi y 16-fenoxi sustituido-17,18,19,20-tetranorprosta-4,5,13 (e)- trienoatos | |
| ES8601874A1 (es) | Un procedimiento para preparar derivados de azetidina sustituidos. | |
| ES8609199A1 (es) | Procedimiento para preparar esteres de acido 2-cloropropio- nico | |
| ES8102555A1 (es) | Un procedimiento para la preparacion de acido 6-cloro-alfa- metilcarbazol-2-acetico | |
| KR850003392A (ko) | 광학적으로 균일한 아제티디논의 제조방법 | |
| ATE185802T1 (de) | Verfahren zur herstellung von 1-methylindazol-3- carbonsäure | |
| PT94127A (pt) | Processo para a producao de 2-oxindol-1-carboxamidas | |
| ES2145905T3 (es) | Procedimiento de produccion de acido 3-isoxazolcarboxilico. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
Ref document number: 273321 Country of ref document: ES |