KR850003392A - 광학적으로 균일한 아제티디논의 제조방법 - Google Patents
광학적으로 균일한 아제티디논의 제조방법 Download PDFInfo
- Publication number
- KR850003392A KR850003392A KR1019840006096A KR840006096A KR850003392A KR 850003392 A KR850003392 A KR 850003392A KR 1019840006096 A KR1019840006096 A KR 1019840006096A KR 840006096 A KR840006096 A KR 840006096A KR 850003392 A KR850003392 A KR 850003392A
- Authority
- KR
- South Korea
- Prior art keywords
- lower alkyl
- signifies
- phenyl
- formula
- benzyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (8)
- 염기 및 일반식(IV)의 설폰산 클로라이드의 존재하에 일반식(II)의 카르복실산의 알칼리금속염과 일반식(III)의 광학적으로 균일한 화합물을 반응시킴을 특징으로 하는 일반식(I)의 광학적으로 균일한 아제리티논의 제조방법.상기식에서 R은 벤질, β-(트리메틸-실릴)-저급알킬 또는 β-할로-저급알킬을 나타내고, R1은 쉽게 분해될 수 있는 보호그룹을 나타내며, R2은 탄소원자에 의해 연결된 임의로 산소를 함유하는 저급 탄화수소 그룹을 나타내고, R3는 탄소원자에 의해 연결된 저급 탄화수소그룹을 나타내며, R2및 R3는 서로 연결되어 환을 형성할 수 있으며, R4는 페닐, 저급 알킬-페닐, 할로페닐, 저급알킬 또는 할로저급알킬을 나타낸다.
- 제1항에 있어서, R이 벤질을 나타내는 일반식(II)의 카르복실산의 알칼리 금속염을 사용하는 방법.
- 제1항 또는 제2항에 있어서, 일반식(II)의 카르복실산의 칼륨염을 사용하는 방법.
- 제1항 내지 제3항중 어느 하나에 있어서, 그룹나타내는 일반식(III)의 화합물을 사용하는 방법.
- 제1항 내지 제5항중 어느 하나에 있어서, R1이 알킬, 벤질 또는 2,4-디메톡시벤질을 나타내는 일반식(III)의 화합물을 사용하는 방법.
- 제1항 내지 제5항중 어느 하나에 있어서, R4가 p-클로로-페닐을 나타내는 일반식(IV)의 화합물을 사용하는 방법.
- 제1항 내지 제6항중 어느 하나에 있어서, 트리에틸아민을 염기로 이용하는 방법.
- 제1항 내지 제7항중 어느 하나에 있어서, 반응이 무수 불활성 유기 용매에서, 바람직하게는 무수 메틸렌 클로라이드중에서 수행되는 방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH5365/83 | 1983-10-03 | ||
CH536583 | 1983-10-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
KR850003392A true KR850003392A (ko) | 1985-06-17 |
Family
ID=4292341
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019840006096A KR850003392A (ko) | 1983-10-03 | 1984-10-02 | 광학적으로 균일한 아제티디논의 제조방법 |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0138113B1 (ko) |
JP (1) | JPS6092263A (ko) |
KR (1) | KR850003392A (ko) |
CN (1) | CN85100624A (ko) |
AT (1) | ATE33830T1 (ko) |
AU (1) | AU572194B2 (ko) |
CA (1) | CA1251455A (ko) |
DE (1) | DE3470736D1 (ko) |
DK (1) | DK411384A (ko) |
IL (1) | IL73089A (ko) |
NZ (1) | NZ209684A (ko) |
PH (1) | PH19418A (ko) |
ZA (1) | ZA847585B (ko) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60139667A (ja) * | 1983-12-27 | 1985-07-24 | Takeda Chem Ind Ltd | アゼチジノンの製造法 |
US5142039A (en) * | 1987-07-31 | 1992-08-25 | Eli Lilly And Company | β-lactam antibiotics |
ATE88186T1 (de) * | 1987-07-31 | 1993-04-15 | Lilly Co Eli | Verfahren zum entschuetzen von 3aminoazetidinonen. |
US5239068A (en) * | 1987-07-31 | 1993-08-24 | Eli Lilly And Company | Bicyclic β-lactam antibiotics |
US4983732A (en) * | 1987-07-31 | 1991-01-08 | Eli Lilly And Company | Method of deprotection of 3-amino azetidinones |
CN112175173B (zh) * | 2020-10-09 | 2022-04-19 | 中国科学技术大学 | 一种烯烃插入率可控的可降解聚α-烯烃材料的制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1262128A (en) * | 1981-08-27 | 1989-10-03 | Christian N. Hubschwerlen | .beta.-lactams |
CA1251454A (en) * | 1983-01-20 | 1989-03-21 | Gerard Schmid | PROCESS FOR THE MANUFACTURE OF .beta.-LACTAMES |
DK36784A (da) * | 1983-02-25 | 1984-08-26 | Hoffmann La Roche | Fremgangsmaade til fremstilling af chirale aldehyder |
JPS60139667A (ja) * | 1983-12-27 | 1985-07-24 | Takeda Chem Ind Ltd | アゼチジノンの製造法 |
-
1984
- 1984-08-28 DK DK411384A patent/DK411384A/da not_active Application Discontinuation
- 1984-09-04 CA CA000462331A patent/CA1251455A/en not_active Expired
- 1984-09-26 IL IL73089A patent/IL73089A/xx unknown
- 1984-09-26 NZ NZ209684A patent/NZ209684A/en unknown
- 1984-09-26 AT AT84111448T patent/ATE33830T1/de not_active IP Right Cessation
- 1984-09-26 EP EP84111448A patent/EP0138113B1/de not_active Expired
- 1984-09-26 ZA ZA847585A patent/ZA847585B/xx unknown
- 1984-09-26 DE DE8484111448T patent/DE3470736D1/de not_active Expired
- 1984-09-28 AU AU33705/84A patent/AU572194B2/en not_active Ceased
- 1984-09-28 PH PH31277A patent/PH19418A/en unknown
- 1984-10-02 JP JP59205690A patent/JPS6092263A/ja active Pending
- 1984-10-02 KR KR1019840006096A patent/KR850003392A/ko not_active Application Discontinuation
-
1985
- 1985-04-01 CN CN198585100624A patent/CN85100624A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
IL73089A (en) | 1988-02-29 |
DK411384D0 (da) | 1984-08-28 |
JPS6092263A (ja) | 1985-05-23 |
CN85100624A (zh) | 1986-07-09 |
PH19418A (en) | 1986-04-10 |
ATE33830T1 (de) | 1988-05-15 |
CA1251455A (en) | 1989-03-21 |
EP0138113A1 (de) | 1985-04-24 |
IL73089A0 (en) | 1984-12-31 |
AU572194B2 (en) | 1988-05-05 |
DK411384A (da) | 1985-04-04 |
EP0138113B1 (de) | 1988-04-27 |
AU3370584A (en) | 1985-04-18 |
DE3470736D1 (en) | 1988-06-01 |
ZA847585B (en) | 1985-05-29 |
NZ209684A (en) | 1987-08-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR870000312A (ko) | 티아졸리딘-4(s)-카르복실산 유도체의 제조 방법 | |
KR880001638A (ko) | 키랄 중간체 | |
KR850003392A (ko) | 광학적으로 균일한 아제티디논의 제조방법 | |
KR840003614A (ko) | 항염 작용을 갖는 피롤아세트 아미드의 제조방법 | |
KR840004104A (ko) | 페닐 피페라진 유도체의 제조방법 | |
KR830001941A (ko) | β-락타마제-억제제로서의 6-B-치환 페닐실란산의 제조방법 | |
GB1346744A (en) | Betalactam compounds and process for preparing same | |
KR910007945A (ko) | 알킬 메틸-3-카브알콕시에틸포스피네이트의 제조방법 | |
ATE56963T1 (de) | Verfahren zur herstellung von aminothiazolessigsaeurederivaten. | |
ATE17250T1 (de) | Zwischenverbindungen fuer die herstellung von cephalosporinen und verfahren zur herstellung dieser zwischenverbindungen. | |
KR830004322A (ko) | 항알러지 및 항궤양제 1-옥소-1H-티아졸로 [3,2-a]피리미딘-2-카복사미드와 그의 중간물질 | |
KR860004004A (ko) | 4-아실옥시-3-옥소- 부티르산 에스테르의 제조방법 | |
KR840008647A (ko) | 대칭 1,4-디하이드로피리딘디카복실 에스테르의 제조방법 | |
KR860000295A (ko) | 옥시캄 유도체의 제조방법 | |
KR840007230A (ko) | β-락타마아제의 제조방법 | |
KR850001740A (ko) | 헤테로고리 화합물의 제조방법 | |
KR850007253A (ko) | d,1-트랜스-소브레롤의 데오필린-7-아세트산 에스테르의 제조방법 | |
KR900016270A (ko) | 폴리올레핀 수지조성물 | |
KR830001969A (ko) | 할로겐화 화합물의 안정화 방법 | |
KR850001742A (ko) | 큐말산 에스테르의 제조방법 | |
KR940019681A (ko) | 베타-락탐 화합물의 제조방법 및 그의 중간체 | |
KR840004759A (ko) | 페니실린과 세팔로스포린 화합물의 제조방법 및 이들의 제조에 사용한 새로운 중간체의 제조방법 | |
KR840002848A (ko) | 유기인산염의 제조방법 | |
KR840002847A (ko) | 유기성 인화합물의 제조방법 | |
KR870002155A (ko) | 디아자포스포린의 제조방법 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A201 | Request for examination | ||
E902 | Notification of reason for refusal | ||
E601 | Decision to refuse application |