ES2032582T3 - Procedimiento para preparar derivados de la oxima del 1,2,5,6,-tetrahidropiridin -3-carboxialdehido. - Google Patents

Procedimiento para preparar derivados de la oxima del 1,2,5,6,-tetrahidropiridin -3-carboxialdehido.

Info

Publication number
ES2032582T3
ES2032582T3 ES198888402129T ES88402129T ES2032582T3 ES 2032582 T3 ES2032582 T3 ES 2032582T3 ES 198888402129 T ES198888402129 T ES 198888402129T ES 88402129 T ES88402129 T ES 88402129T ES 2032582 T3 ES2032582 T3 ES 2032582T3
Authority
ES
Spain
Prior art keywords
unsaturated
branched
saturated
linear
tetrahidropiridin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888402129T
Other languages
English (en)
Spanish (es)
Inventor
Emilio Toja
Carla Bonetti
Fernando Barzaghi
Giulio Galliani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Application granted granted Critical
Publication of ES2032582T3 publication Critical patent/ES2032582T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/94—Oxygen atom, e.g. piperidine N-oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES198888402129T 1987-08-21 1988-08-19 Procedimiento para preparar derivados de la oxima del 1,2,5,6,-tetrahidropiridin -3-carboxialdehido. Expired - Lifetime ES2032582T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21691/87A IT1222529B (it) 1987-08-21 1987-08-21 Derivati dell' ossima della 1,2,5,6-tetraidropirdin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali

Publications (1)

Publication Number Publication Date
ES2032582T3 true ES2032582T3 (es) 1993-02-16

Family

ID=11185470

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888402129T Expired - Lifetime ES2032582T3 (es) 1987-08-21 1988-08-19 Procedimiento para preparar derivados de la oxima del 1,2,5,6,-tetrahidropiridin -3-carboxialdehido.

Country Status (11)

Country Link
US (1) US4902699A (enExample)
EP (1) EP0308284B1 (enExample)
JP (1) JP2660430B2 (enExample)
AT (1) ATE73445T1 (enExample)
CA (1) CA1338494C (enExample)
DE (1) DE3869028D1 (enExample)
ES (1) ES2032582T3 (enExample)
GR (1) GR3004652T3 (enExample)
IT (1) IT1222529B (enExample)
MX (1) MX12708A (enExample)
PT (1) PT88301B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231107A (en) * 1987-08-21 1993-07-27 Roussel Uclaf Derivatives of the oxime of 1,2,5,6-tetrahydropyridine 3-carboxaldehyde, the process for their preparation, their use as medicaments and the compositions containing them
PT90266B (pt) * 1988-04-15 1994-07-29 Beecham Group Plc Processo para a preparacao de compostos azabiciclicos
IT1229491B (it) * 1988-12-28 1991-09-03 Roussel Maestretti S P A Ora R Derivati della 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro impiego come sostanze medicinali
SG48315A1 (en) * 1989-04-13 1998-04-17 Beecham Group Plc Novel compounds
US5278170A (en) * 1989-04-13 1994-01-11 Beecham Group P.L.C. Azabicylo oxime compounds
IT1240603B (it) * 1990-03-14 1993-12-17 Roussel Maestretti Spa Derivati della 1,2,5,6-tetraidropiridina 3- carbossaldeide ossima, loro procedimento di preparazione e loro impiego come sostanza medicinale
IT1241138B (it) * 1990-05-15 1993-12-29 Roussel Pharma Derivati dell'ossina della 1,2,5,6- tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali
WO1992003435A1 (en) * 1990-08-24 1992-03-05 Beecham Group Plc Azabicyclic compounds, process and intermediates for their preparation and pharmaceutical compositions containing them
GB9019095D0 (en) * 1990-09-01 1990-10-17 Beecham Group Plc Novel compounds
CA2093823A1 (en) * 1990-10-12 1992-04-13 Steven M. Bromidge 1,2,5,6-tetrahydropyridine oxime derivatives
US5424301A (en) * 1993-02-01 1995-06-13 Warner-Lambert Company Starch stabilized o-substituted tetrahydropyridine oxime cholinergic agents
EP1132085A4 (en) * 1998-11-25 2003-04-23 Daiichi Radioisotope Lab MEDICINAL PRODUCTS AND REAGENTS CONTAIN THE N-ACYLOXYLATED CYCLOALKYL COMPOUNDS AS ACTIVE INGREDIENTS

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA725633A (en) * 1966-01-11 Dr. F. Raschig, G.M.B.H., Chemical Works Ethers of pyridine-aldoxime n-oxides
US3004979A (en) * 1961-10-17 Oximes of certain tetrahydropyridine
FR1258847A (fr) * 1960-02-12 1961-04-21 Ciba Geigy Procédé de préparation de nouveaux dérivés pyridiniques, entre autres de l'oxime de la l-méthyl-3 ou 4-acétyl-1, 2, 5, 6-tétrahydropyridine
US4710508A (en) * 1986-12-08 1987-12-01 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents

Also Published As

Publication number Publication date
PT88301A (pt) 1989-06-30
JP2660430B2 (ja) 1997-10-08
ATE73445T1 (de) 1992-03-15
IT8721691A0 (it) 1987-08-21
PT88301B (pt) 1995-03-31
DE3869028D1 (de) 1992-04-16
CA1338494C (fr) 1996-07-30
IT1222529B (it) 1990-09-05
US4902699A (en) 1990-02-20
EP0308284B1 (fr) 1992-03-11
JPH01110671A (ja) 1989-04-27
MX12708A (es) 1993-11-01
EP0308284A1 (fr) 1989-03-22
GR3004652T3 (enExample) 1993-04-28

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