ES2023892B3 - Metodo y aparato para la granulacion y la obtencion de productos granulados. - Google Patents

Metodo y aparato para la granulacion y la obtencion de productos granulados.

Info

Publication number
ES2023892B3
ES2023892B3 ES87302115T ES87302115T ES2023892B3 ES 2023892 B3 ES2023892 B3 ES 2023892B3 ES 87302115 T ES87302115 T ES 87302115T ES 87302115 T ES87302115 T ES 87302115T ES 2023892 B3 ES2023892 B3 ES 2023892B3
Authority
ES
Spain
Prior art keywords
meltable
spreader means
feed material
powdery
melted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87302115T
Other languages
English (en)
Inventor
Robert Edward Sparks
Norbert Simon Mason
Michael Center
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Washington University Technology Associates WUTA
Original Assignee
Washington University Technology Associates WUTA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Washington University Technology Associates WUTA filed Critical Washington University Technology Associates WUTA
Application granted granted Critical
Publication of ES2023892B3 publication Critical patent/ES2023892B3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C67/00—Shaping techniques not covered by groups B29C39/00 - B29C65/00, B29C70/00 or B29C73/00
    • B29C67/02—Moulding by agglomerating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/14—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic in rotating dishes or pans
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/28—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic using special binding agents
ES87302115T 1986-03-12 1987-03-11 Metodo y aparato para la granulacion y la obtencion de productos granulados. Expired - Lifetime ES2023892B3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/838,828 US5019302A (en) 1986-03-12 1986-03-12 Method for granulation

Publications (1)

Publication Number Publication Date
ES2023892B3 true ES2023892B3 (es) 1992-02-16

Family

ID=25278149

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87302115T Expired - Lifetime ES2023892B3 (es) 1986-03-12 1987-03-11 Metodo y aparato para la granulacion y la obtencion de productos granulados.

Country Status (24)

Country Link
US (1) US5019302A (es)
EP (1) EP0237345B1 (es)
JP (1) JPH01501768A (es)
KR (1) KR880701175A (es)
CN (1) CN1013479B (es)
AT (1) ATE64547T1 (es)
AU (1) AU591268B2 (es)
BR (1) BR8707635A (es)
CA (1) CA1321692C (es)
CS (1) CS150887A3 (es)
DD (1) DD265336A5 (es)
DE (1) DE3770843D1 (es)
EG (1) EG17922A (es)
ES (1) ES2023892B3 (es)
FI (1) FI884162A0 (es)
GR (1) GR3002725T3 (es)
HU (1) HUT48522A (es)
IL (1) IL81760A (es)
IS (1) IS1499B (es)
NZ (1) NZ219532A (es)
PL (1) PL264591A1 (es)
PT (1) PT84438B (es)
WO (1) WO1987005561A1 (es)
ZA (1) ZA871163B (es)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5100592A (en) * 1986-03-12 1992-03-31 Washington University Technology Associated, Inc. Method and apparatus for granulation and granulated product
ES2032205T3 (es) * 1986-11-14 1993-01-16 Ciba-Geigy Ag Procedimiento para la obtencion de un sistema osmotico oral para la administracion de metoprolol.
US5137669A (en) * 1988-03-02 1992-08-11 Endocon, Inc. Manufacture of partially fused peptide pellet
JP3191948B2 (ja) * 1990-04-12 2001-07-23 塩野義製薬株式会社 被覆製剤およびその製造法
US5290569A (en) * 1990-04-12 1994-03-01 Shionogi & Co., Ltd. Coated composition and its preparation process
US5342557A (en) * 1990-11-27 1994-08-30 United States Surgical Corporation Process for preparing polymer particles
US5143662A (en) * 1991-02-12 1992-09-01 United States Surgical Corporation Process for preparing particles of bioabsorbable polymer
US5429825A (en) * 1992-06-26 1995-07-04 Mcneil-Ppc, Inc. Rotomelt granulation
US5628945A (en) * 1992-08-03 1997-05-13 Riman; Richard E. Multicomponent powder mixing process and compositions produced thereby
US5447565A (en) * 1993-12-10 1995-09-05 Wm. Wrigley Jr. Company Apparatus and method for coating particles
US5508276A (en) 1994-07-18 1996-04-16 Eli Lilly And Company Duloxetine enteric pellets
US5700497A (en) * 1995-06-12 1997-12-23 Kason Corporation Vibratory agglomerator
WO1998022474A1 (fr) * 1996-11-20 1998-05-28 Otkrytoe Aktsionernoe Obschestvo 'aviabor' Dzerzhinsky Opytny Zavod Aviatsionnykh Materialov Procede de fabrication de granules d'une substance thermolabile et installation requise
KR100354557B1 (ko) * 1997-05-15 2002-09-30 간사이 페인트 가부시키가이샤 조립분체도료 및 그 제조방법
DE19933289A1 (de) * 1999-07-15 2001-01-18 Basf Ag Verfahren zur Herstellung eines Granulats aus einer Schmelze
US6273260B1 (en) 2000-03-08 2001-08-14 Eli Lilly And Company Pharmaceutical packaging system
US6691765B2 (en) 2001-08-07 2004-02-17 Noram Technology, Ltd. Products for the manufacture of molds and cores used in metal casting and a method for their manufacture and recycle from crushed rock
US6631808B2 (en) 2001-08-07 2003-10-14 Particle And Coating Technologies, Inc. Air classifier system for the separation of particles
US6932286B2 (en) * 2001-11-07 2005-08-23 Fred P. Smith Combination drop and broadcast spreader
AU2003282375A1 (en) * 2003-02-05 2004-08-30 Ipca Laboratories Limited Pharmaceutical compositions and process of production thereof
WO2005000237A2 (en) * 2003-06-25 2005-01-06 University Of Tennessee Research Foundation Granules containing biologically active substances
EP1491253A1 (en) * 2003-06-26 2004-12-29 Urea Casale S.A. Fluid bed granulation process and apparatus
US7314640B2 (en) * 2003-07-11 2008-01-01 Mongkol Sriwongjanya Formulation and process for drug loaded cores
CA2547773A1 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Spray-congeal process using an extruder for preparing multiparticulate azithromycin compositions containing preferably a poloxamer and a glyceride
WO2005053656A1 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Spray-congeal process using an extruder for preparing multiparticulate crystalline drug compositions containing preferably a poloxamer and a glyceride
WO2005053651A1 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Multiparticulate compositions with improved stability
WO2005053639A2 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Controlled release multiparticulates formed with dissolution enhancers
WO2005053655A1 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Method for making pharmaceutical multiparticulates
WO2005053652A1 (en) 2003-12-04 2005-06-16 Pfizer Products Inc. Multiparticulate crystalline drug compositions containing a poloxamer and a glyceride
US6984403B2 (en) * 2003-12-04 2006-01-10 Pfizer Inc. Azithromycin dosage forms with reduced side effects
ES2378233T3 (es) * 2004-09-21 2012-04-10 G & I Irtech S.L. Proceso y máquina para la aglomeración y/o secado de materiales en polvo usando radiación infrarroja
US20070053983A1 (en) * 2005-09-06 2007-03-08 Girish Jain Extended release compositions of metoprolol succinate
US7261529B2 (en) * 2005-09-07 2007-08-28 Southwest Research Institute Apparatus for preparing biodegradable microparticle formulations containing pharmaceutically active agents
US9693967B2 (en) * 2005-09-07 2017-07-04 Southwest Research Institute Biodegradable microparticle pharmaceutical formulations exhibiting improved released rates
US7758778B2 (en) * 2005-09-07 2010-07-20 Southwest Research Institute Methods for preparing biodegradable microparticle formulations containing pharmaceutically active agents
US8563032B2 (en) 2005-12-05 2013-10-22 Roxane Laboratories, Inc. Formulation and manufacturing process for calcium acetate capsules
US20110217553A1 (en) * 2007-12-20 2011-09-08 Warner Isiah M Frozen Ionic Liquid Microparticles and Nanoparticles, and Methods for their Synthesis and Use
JP2010099586A (ja) * 2008-10-23 2010-05-06 National Institute For Materials Science 固形粒子の製造装置及び製造方法
JP2012520176A (ja) * 2009-03-16 2012-09-06 ガバエ テクノロジーズ，エルエルシー 回転毛細管を用いて粒子を生成する装置、システム及び方法
CN103108830B (zh) * 2010-10-04 2014-07-16 3M创新有限公司 通过添加疏水性纳米粒子而改变粒子的溶解速率的方法
CN104062210B (zh) * 2013-12-13 2018-04-27 郑州轻工业学院 颗粒采集及检测系统
CA3018828C (en) 2014-09-17 2021-05-11 Steerlife India Private Limited Effervescent composition and method of making it
CN107703987B (zh) * 2014-12-23 2020-03-13 齐鲁工业大学 喷油润滑下油温和环境温度的低温控制装置的控制方法
CN105128165A (zh) * 2015-07-13 2015-12-09 北京化工大学 一种离心法制备聚合物超细颗粒的装置
CN105342857A (zh) * 2015-12-07 2016-02-24 江苏知原药业有限公司 一种中药滴丸制备设备
WO2017098481A1 (en) 2015-12-12 2017-06-15 Steerlife India Private Limited Effervescent compositions of metformin and processes for preparation thereof
CN106994316A (zh) * 2017-05-31 2017-08-01 安硕文教用品（上海）股份有限公司 一种铅笔料颗粒机
CN107362047B (zh) * 2017-08-25 2023-02-17 七次方家用电器（上海）有限公司 分料机构
CN108889238A (zh) * 2018-06-29 2018-11-27 东北大学 液态氯化镁粒化装置及余热回收系统与方法
CN112371054A (zh) * 2020-10-22 2021-02-19 武汉木兰山水生态农业发展有限公司 一种微生物肥料离心造粒方法

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1671866A (en) * 1924-12-18 1928-05-29 Calco Chemical Company Globular sodium bisulphate and method of making the same
BE491927A (es) * 1948-10-30
US2818601A (en) * 1955-10-27 1958-01-07 United States Steel Corp Disc-type balling device
DE1033640B (de) * 1956-06-30 1958-07-10 Metallgesellschaft Ag Granulierteller
US2986772A (en) * 1959-05-27 1961-06-06 Jr George Patton Eccentric rolling of powder and bonding agent into spherical pellets
BE636568A (es) * 1961-01-31
US3208822A (en) * 1961-08-16 1965-09-28 Philadelphia Quartz Co Spherical particles of anhydrous sodium metasilicate and method of manufacture thereof
DE1454743B2 (de) * 1962-06-07 1970-05-14 Beck, Erich, 6520 Worms Verfahren und Vorrichtung zum Verdichten und Agglomerieren von pulverförmigen bis körnigen thermoplastischen Stoffen
BE640616A (es) * 1962-12-19
GB1037792A (en) * 1964-03-13 1966-08-03 Konditerskaja Fabrika Im Marat Enteric coated oral vaccines for intestinal infections
US3295838A (en) * 1964-08-24 1967-01-03 Mcdowell Wellman Eng Co Conditioner for premoistening dry powders
DE1667178A1 (de) * 1967-05-16 1971-06-09 Metallgesellschaft Ag Verfahren zur Herstellung von Agglomeraten aus feinteiligen festen Stoffen
USRE27214E (en) * 1968-05-31 1971-11-02 Method and apparatus for making spherical granules
US3531562A (en) * 1969-03-12 1970-09-29 Monsanto Co Increasing the density of thermoplastic foam scrap
GB1324116A (en) * 1970-10-14 1973-07-18 Koninklijke Gist Spiritus Method and apparatus for preparing an enzyme composition in particulate form
US3966975A (en) * 1970-12-21 1976-06-29 Aktieselskabet Niro Atomizer Method for producing agglomerated powders and apparatus for performing the method
US3743464A (en) * 1971-08-24 1973-07-03 Fmc Corp Continuous sphering apparatus
FR2236483B1 (es) * 1973-07-12 1976-11-12 Choay Sa
NO133872C (es) * 1974-07-26 1976-07-14 Norsk Hydro As
US4174937A (en) * 1975-03-19 1979-11-20 The United States Of America As Represented By The Secretary Of The Interior Powder agglomerator and its method of use
US4157371A (en) * 1975-03-19 1979-06-05 The United States Of America As Represented By The Secretary Of The Interior Method of agglomerating fine powders
SE418247B (sv) * 1975-11-17 1981-05-18 Haessle Ab Sett att framstella kroppar med reglerad frigoring av en aktiv komponent
US4256677A (en) * 1976-04-12 1981-03-17 Magnavox Government And Industrial Electronics Co. Apparatus and method for making small spheres
JPS5446826A (en) * 1977-08-24 1979-04-13 Yamanouchi Pharmaceut Co Ltd Slow-release rectal suppository
US4181708A (en) * 1977-09-02 1980-01-01 Eastman Kodak Company Rumen-stable pellets
EP0008083A1 (de) * 1978-08-15 1980-02-20 Ciba-Geigy Ag Verfahren zur Herstellung von Granulaten schwerschmelzbarer Zusatzstoffe für Kunststoffe, insbesondere von Pigmenten, durch thermische Rollgranulierung und die so erhaltenen Granulate
US4205060A (en) * 1978-12-20 1980-05-27 Pennwalt Corporation Microcapsules containing medicament-polymer salt having a water-insoluble polymer sheath, their production and their use
US4399122A (en) * 1980-02-07 1983-08-16 E. I. Du Pont De Nemours And Company Controlled release granules
US4331654A (en) * 1980-06-13 1982-05-25 Eli Lilly And Company Magnetically-localizable, biodegradable lipid microspheres
JPS5839618A (ja) * 1981-09-04 1983-03-08 Chugai Pharmaceut Co Ltd 持続性積層錠剤
US4507276A (en) * 1982-08-20 1985-03-26 Bristol-Myers Company Analgesic capsule
US4643662A (en) * 1984-06-08 1987-02-17 Monsanto Company Pelletizing apparatus

Also Published As

Publication number Publication date
FI884162A (fi) 1988-09-09
PL264591A1 (en) 1988-04-28
PT84438A (en) 1987-04-01
AU7162687A (en) 1987-10-09
NZ219532A (en) 1990-01-29
IL81760A0 (en) 1987-10-20
HUT48522A (en) 1989-06-28
GR3002725T3 (en) 1993-01-25
WO1987005561A1 (en) 1987-09-24
KR880701175A (ko) 1988-07-26
ATE64547T1 (de) 1991-07-15
AU591268B2 (en) 1989-11-30
US5019302A (en) 1991-05-28
EP0237345A2 (en) 1987-09-16
IS3199A7 (is) 1987-09-13
BR8707635A (pt) 1989-03-14
EP0237345A3 (en) 1988-11-02
ZA871163B (en) 1987-09-30
FI884162A0 (fi) 1988-09-09
EG17922A (en) 1991-06-30
CA1321692C (en) 1993-08-31
DD265336A5 (de) 1989-03-01
CN1013479B (zh) 1991-08-14
CN87101837A (zh) 1987-12-02
IL81760A (en) 1990-04-29
DE3770843D1 (de) 1991-07-25
CS150887A3 (en) 1992-11-18
JPH01501768A (ja) 1989-06-22
PT84438B (pt) 1989-10-04
EP0237345B1 (en) 1991-06-19
IS1499B (is) 1992-07-30

Similar Documents

Publication Publication Date Title
ES2023892B3 (es) Metodo y aparato para la granulacion y la obtencion de productos granulados.
SE9200858L (sv) Metod för framställning av pellets med fördröjd frisättning
CA2098600A1 (en) Method and apparatus for granulation
NO20006487L (no) Fremgangsmåte for fremstilling av granuler av gjödselforbindelser
US2887723A (en) Process for granulating material
US3772037A (en) Static bed agglomeration
JPS57209633A (en) Granulating method and apparatus therefor
TH8006EX (th) กรรมวิธีและเครื่องมือสำหรับการทำให้เป็นเมล็ดและผลผลิตที่ทำให้เป็นเมล็ด
TH8006A (th) กรรมวิธีและเครื่องมือสำหรับการทำให้เป็นเมล็ดและผลผลิตที่ทำให้เป็นเมล็ด
DE2436863A1 (de) Verfahren zum granulieren pulvriger stoffe
JPS5621830A (en) Film being excellent in printing property
JPS5932288B2 (ja) 混合物の分離法
JPH0751562A (ja) カプセル化物の製造法
JPS543870A (en) Method of forming uneven pattern on metal sheet
JPH0472796B2 (es)
JPS5778938A (en) Grinding granulator
JPH0357838B2 (es)
JPS5562002A (en) Preparation of solid rodenticide
JPS5756306A (en) Manufacture of sodium percarbonate with superior wear resistance
GR66803B (es)
JPS57171632A (en) Pretreatment of starting material for sintering
ES224455U (es) Dispositivo granulador de material.