DE3770843D1 - Verfahren und vorrichtung zum granulieren und granuliertes produkt. - Google Patents

Verfahren und vorrichtung zum granulieren und granuliertes produkt.

Info

Publication number
DE3770843D1
DE3770843D1 DE8787302115T DE3770843T DE3770843D1 DE 3770843 D1 DE3770843 D1 DE 3770843D1 DE 8787302115 T DE8787302115 T DE 8787302115T DE 3770843 T DE3770843 T DE 3770843T DE 3770843 D1 DE3770843 D1 DE 3770843D1
Authority
DE
Germany
Prior art keywords
meltable
spreader means
feed material
powdery
melted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8787302115T
Other languages
English (en)
Inventor
Robert Edward Sparks
Norbert Simon Mason
Michael Center
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Washington
Washington University Technology Associates WUTA
Original Assignee
University of Washington
Washington University Technology Associates WUTA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Washington, Washington University Technology Associates WUTA filed Critical University of Washington
Application granted granted Critical
Publication of DE3770843D1 publication Critical patent/DE3770843D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C67/00—Shaping techniques not covered by groups B29C39/00 - B29C65/00, B29C70/00 or B29C73/00
    • B29C67/02—Moulding by agglomerating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/14—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic in rotating dishes or pans
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/28—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic using special binding agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Mechanical Engineering (AREA)
  • Disintegrating Or Milling (AREA)
  • Medicinal Preparation (AREA)
  • Glanulating (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Seasonings (AREA)
  • Control And Other Processes For Unpacking Of Materials (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
  • Saccharide Compounds (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE8787302115T 1986-03-12 1987-03-11 Verfahren und vorrichtung zum granulieren und granuliertes produkt. Expired - Lifetime DE3770843D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/838,828 US5019302A (en) 1986-03-12 1986-03-12 Method for granulation

Publications (1)

Publication Number Publication Date
DE3770843D1 true DE3770843D1 (de) 1991-07-25

Family

ID=25278149

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787302115T Expired - Lifetime DE3770843D1 (de) 1986-03-12 1987-03-11 Verfahren und vorrichtung zum granulieren und granuliertes produkt.

Country Status (24)

Country Link
US (1) US5019302A (de)
EP (1) EP0237345B1 (de)
JP (1) JPH01501768A (de)
KR (1) KR880701175A (de)
CN (1) CN1013479B (de)
AT (1) ATE64547T1 (de)
AU (1) AU591268B2 (de)
BR (1) BR8707635A (de)
CA (1) CA1321692C (de)
CS (1) CS150887A3 (de)
DD (1) DD265336A5 (de)
DE (1) DE3770843D1 (de)
EG (1) EG17922A (de)
ES (1) ES2023892B3 (de)
FI (1) FI884162A (de)
GR (1) GR3002725T3 (de)
HU (1) HUT48522A (de)
IL (1) IL81760A (de)
IS (1) IS1499B (de)
NZ (1) NZ219532A (de)
PL (1) PL264591A1 (de)
PT (1) PT84438B (de)
WO (1) WO1987005561A1 (de)
ZA (1) ZA871163B (de)

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JP3191948B2 (ja) * 1990-04-12 2001-07-23 塩野義製薬株式会社 被覆製剤およびその製造法
US5290569A (en) * 1990-04-12 1994-03-01 Shionogi & Co., Ltd. Coated composition and its preparation process
US5342557A (en) * 1990-11-27 1994-08-30 United States Surgical Corporation Process for preparing polymer particles
US5143662A (en) * 1991-02-12 1992-09-01 United States Surgical Corporation Process for preparing particles of bioabsorbable polymer
US5429825A (en) * 1992-06-26 1995-07-04 Mcneil-Ppc, Inc. Rotomelt granulation
US5628945A (en) * 1992-08-03 1997-05-13 Riman; Richard E. Multicomponent powder mixing process and compositions produced thereby
US5447565A (en) * 1993-12-10 1995-09-05 Wm. Wrigley Jr. Company Apparatus and method for coating particles
US5508276A (en) 1994-07-18 1996-04-16 Eli Lilly And Company Duloxetine enteric pellets
US5700497A (en) * 1995-06-12 1997-12-23 Kason Corporation Vibratory agglomerator
WO1998022474A1 (fr) * 1996-11-20 1998-05-28 Otkrytoe Aktsionernoe Obschestvo 'aviabor' Dzerzhinsky Opytny Zavod Aviatsionnykh Materialov Procede de fabrication de granules d'une substance thermolabile et installation requise
EP0982380A4 (de) * 1997-05-15 2001-12-05 Kansai Paint Co Ltd Granulierter pulverlack und herstellungsverfahren
DE19933289A1 (de) * 1999-07-15 2001-01-18 Basf Ag Verfahren zur Herstellung eines Granulats aus einer Schmelze
US6273260B1 (en) 2000-03-08 2001-08-14 Eli Lilly And Company Pharmaceutical packaging system
US6691765B2 (en) * 2001-08-07 2004-02-17 Noram Technology, Ltd. Products for the manufacture of molds and cores used in metal casting and a method for their manufacture and recycle from crushed rock
US6631808B2 (en) 2001-08-07 2003-10-14 Particle And Coating Technologies, Inc. Air classifier system for the separation of particles
US6932286B2 (en) * 2001-11-07 2005-08-23 Fred P. Smith Combination drop and broadcast spreader
AU2003282375A1 (en) * 2003-02-05 2004-08-30 Ipca Laboratories Limited Pharmaceutical compositions and process of production thereof
US20040265378A1 (en) * 2003-06-25 2004-12-30 Yingxu Peng Method and compositions for producing granules containing high concentrations of biologically active substances
EP1491253A1 (de) * 2003-06-26 2004-12-29 Urea Casale S.A. Vorrichtung und Verfahren zur Wirbelschichtgranulation
US7314640B2 (en) * 2003-07-11 2008-01-01 Mongkol Sriwongjanya Formulation and process for drug loaded cores
BRPI0416534A (pt) * 2003-12-04 2007-01-09 Pfizer Prod Inc composições multiparticuladas com estabilidade melhorada
ATE399536T1 (de) * 2003-12-04 2008-07-15 Pfizer Prod Inc Verfahren zur herstellung von pharmazeutischen multiteilchenförmigen produkten
AU2004294813A1 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Spray-congeal process using an extruder for preparing multiparticulate azithromycin compositions containing preferably a poloxamer and a glyceride
WO2005053639A2 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Controlled release multiparticulates formed with dissolution enhancers
BRPI0417348A (pt) * 2003-12-04 2007-03-13 Pfizer Prod Inc processo de gelatinização por spray com utilização de uma extrusora para preparação de composições de droga cristalina multiparticulada contendo preferencialmente um poloxámero e um glicerìdeo
US6984403B2 (en) * 2003-12-04 2006-01-10 Pfizer Inc. Azithromycin dosage forms with reduced side effects
WO2005053652A1 (en) 2003-12-04 2005-06-16 Pfizer Products Inc. Multiparticulate crystalline drug compositions containing a poloxamer and a glyceride
JP4637178B2 (ja) * 2004-09-21 2011-02-23 ヴィヴェス，ホアン イグレシアス 赤外線を用いた粉末材料の造粒及び／又は乾燥方法及び装置
US20070053983A1 (en) * 2005-09-06 2007-03-08 Girish Jain Extended release compositions of metoprolol succinate
US7261529B2 (en) * 2005-09-07 2007-08-28 Southwest Research Institute Apparatus for preparing biodegradable microparticle formulations containing pharmaceutically active agents
US7758778B2 (en) * 2005-09-07 2010-07-20 Southwest Research Institute Methods for preparing biodegradable microparticle formulations containing pharmaceutically active agents
US9693967B2 (en) * 2005-09-07 2017-07-04 Southwest Research Institute Biodegradable microparticle pharmaceutical formulations exhibiting improved released rates
US8563032B2 (en) 2005-12-05 2013-10-22 Roxane Laboratories, Inc. Formulation and manufacturing process for calcium acetate capsules
WO2009082618A2 (en) * 2007-12-20 2009-07-02 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Frozen lonic liquid microparticles and nanoparticles, and methods for their synthesis and use
JP2010099586A (ja) * 2008-10-23 2010-05-06 National Institute For Materials Science 固形粒子の製造装置及び製造方法
WO2010105352A1 (en) * 2009-03-16 2010-09-23 Gabae Technologies, Llc Apparatus, systems and methods for producing particles using rotating capillaries
CN103108830B (zh) * 2010-10-04 2014-07-16 3M创新有限公司 通过添加疏水性纳米粒子而改变粒子的溶解速率的方法
CN104062210B (zh) * 2013-12-13 2018-04-27 郑州轻工业学院 颗粒采集及检测系统
BR112017005362A2 (pt) 2014-09-17 2018-01-23 Steerlife India Private Ltd composição, forma de dosagem sólida oral, processo para preparação de grânulos efervescentes porosos, processador de parafuso duplo, e, grânulos efervescentes porosos.
CN107703992B (zh) * 2014-12-23 2019-12-06 齐鲁工业大学 喷油润滑低温控制装置的电气系统
CN105128165A (zh) * 2015-07-13 2015-12-09 北京化工大学 一种离心法制备聚合物超细颗粒的装置
CN105342857A (zh) * 2015-12-07 2016-02-24 江苏知原药业有限公司 一种中药滴丸制备设备
US11219594B2 (en) 2015-12-12 2022-01-11 Steerlife India Private Limited Effervescent compositions of metformin and processes for preparation thereof
CN106994316A (zh) * 2017-05-31 2017-08-01 安硕文教用品（上海）股份有限公司 一种铅笔料颗粒机
CN107362047B (zh) * 2017-08-25 2023-02-17 七次方家用电器（上海）有限公司 分料机构
CN108889238A (zh) * 2018-06-29 2018-11-27 东北大学 液态氯化镁粒化装置及余热回收系统与方法
CN112371054A (zh) * 2020-10-22 2021-02-19 武汉木兰山水生态农业发展有限公司 一种微生物肥料离心造粒方法

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Also Published As

Publication number Publication date
NZ219532A (en) 1990-01-29
PT84438B (pt) 1989-10-04
ATE64547T1 (de) 1991-07-15
ES2023892B3 (es) 1992-02-16
HUT48522A (en) 1989-06-28
JPH01501768A (ja) 1989-06-22
PT84438A (en) 1987-04-01
PL264591A1 (en) 1988-04-28
FI884162A0 (fi) 1988-09-09
IS1499B (is) 1992-07-30
EP0237345A2 (de) 1987-09-16
FI884162A (fi) 1988-09-09
DD265336A5 (de) 1989-03-01
US5019302A (en) 1991-05-28
KR880701175A (ko) 1988-07-26
WO1987005561A1 (en) 1987-09-24
CA1321692C (en) 1993-08-31
EP0237345A3 (en) 1988-11-02
AU7162687A (en) 1987-10-09
ZA871163B (en) 1987-09-30
IL81760A0 (en) 1987-10-20
BR8707635A (pt) 1989-03-14
EP0237345B1 (de) 1991-06-19
EG17922A (en) 1991-06-30
GR3002725T3 (en) 1993-01-25
CS150887A3 (en) 1992-11-18
CN87101837A (zh) 1987-12-02
IS3199A7 (is) 1987-09-13
CN1013479B (zh) 1991-08-14
IL81760A (en) 1990-04-29
AU591268B2 (en) 1989-11-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee