ES2019863B3 - Nuevos derivados polioxigenados de ladano. procedimientos de obtencion de aplicaciones como medicamentos - Google Patents

Nuevos derivados polioxigenados de ladano. procedimientos de obtencion de aplicaciones como medicamentos

Info

Publication number
ES2019863B3
ES2019863B3 ES86113486T ES86113486T ES2019863B3 ES 2019863 B3 ES2019863 B3 ES 2019863B3 ES 86113486 T ES86113486 T ES 86113486T ES 86113486 T ES86113486 T ES 86113486T ES 2019863 B3 ES2019863 B3 ES 2019863B3
Authority
ES
Spain
Prior art keywords
polyoxygenated
derivatives
ladano
medicines
procedures
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES86113486T
Other languages
English (en)
Inventor
Yatendra Khandelwal
Ramanujam No 205 Rajgopalan
Alihussein Nomanbhai Dohadwalla
Richard Helmut Rupp
Souza Noel John De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2019863B3 publication Critical patent/ES2019863B3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
ES86113486T 1985-10-02 1986-10-01 Nuevos derivados polioxigenados de ladano. procedimientos de obtencion de aplicaciones como medicamentos Expired - Lifetime ES2019863B3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853535086 DE3535086A1 (de) 1985-10-02 1985-10-02 Neue polyoxygenierte labdan-derivate, verfahren zu ihrer herstellung und ihre anwendung als medikamente

Publications (1)

Publication Number Publication Date
ES2019863B3 true ES2019863B3 (es) 1991-07-16

Family

ID=6282512

Family Applications (1)

Application Number Title Priority Date Filing Date
ES86113486T Expired - Lifetime ES2019863B3 (es) 1985-10-02 1986-10-01 Nuevos derivados polioxigenados de ladano. procedimientos de obtencion de aplicaciones como medicamentos

Country Status (14)

Country Link
EP (1) EP0217372B1 (es)
JP (1) JPS6289677A (es)
KR (1) KR870004051A (es)
AT (1) ATE60054T1 (es)
AU (1) AU606036B2 (es)
DE (2) DE3535086A1 (es)
DK (1) DK468186A (es)
ES (1) ES2019863B3 (es)
GR (1) GR3001559T3 (es)
HU (1) HU203234B (es)
IL (1) IL80201A0 (es)
IN (2) IN163242B (es)
PT (1) PT83478B (es)
ZA (1) ZA867495B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE62683T1 (de) * 1985-03-01 1991-05-15 Hoechst Roussel Pharma Labdanderivate, verfahren zu deren herstellung und deren verwendung als arzneimittel.
US4963537A (en) * 1985-03-01 1990-10-16 Hoechst-Roussel Pharmaceuticals Inc. Labdane compounds, pharmaceutical compositions and use
JPS6310783A (ja) * 1985-11-15 1988-01-18 Nippon Kayaku Co Ltd 新規フオルスコリン誘導体
AU591196B2 (en) * 1985-11-15 1989-11-30 Nippon Kayaku Kabushiki Kaisha Novel forskolin derivatives
DE3623300A1 (de) * 1986-07-11 1988-01-21 Hoechst Ag 7-acyloxy-6-aminoacyloxypolyoxylabdane, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US5646175A (en) * 1987-12-28 1997-07-08 Hoechst Marion Roussel, Inc. Carbamoyloxylabdane compounds
US4920146A (en) * 1986-12-29 1990-04-24 Hoechst Roussel Pharmaceuticals Inc. Carbamoyloxylabdane compounds useful in reducing intraocular pressure
IN166900B (es) * 1987-06-03 1990-08-04 Hoechst India
JPH0684367B2 (ja) * 1987-06-29 1994-10-26 日本化薬株式会社 フオルスコリン誘導体の新規製造法
JP2504934B2 (ja) * 1987-06-29 1996-06-05 日本化薬株式会社 １，６，７−トリアシルフオルスコリン誘導体
US5846992A (en) * 1987-10-08 1998-12-08 Hoechst Marion Roussel, Inc. Synergistic intraocular pressure lowering combinations
US4902696A (en) * 1987-10-08 1990-02-20 Hoechst-Roussel Pharmaceuticals, Inc. Synergistic intraocular pressure lowering combinations
US4883793A (en) * 1988-05-09 1989-11-28 Hoechst-Roussel Pharmaceuticals Inc. Hydrazinocarbonyloxylabdanes for treating cardiac failure
EP0447962A1 (en) * 1990-03-17 1991-09-25 Hoechst Aktiengesellschaft Labdanes and process for their preparation
RU2034840C1 (ru) * 1990-07-24 1995-05-10 Хехст АГ СПОСОБ ПОЛУЧЕНИЯ ПРОИЗВОДНЫХ 6-бета-(3-ЗАМЕЩЕННОГО АМИНО)-ПРОПИОНИЛОКСИ-7-ДИАЦЕТИЛФОРСКОЛИНА ИЛИ ИХ ФАРМАЦЕВТИЧЕСКИ ПРИЕМЛЕМЫХ СОЛЕЙ
JP3557095B2 (ja) * 1998-04-20 2004-08-25 高砂香料工業株式会社 メラニン産生抑制剤

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2557784C2 (de) 1975-12-22 1986-04-17 Hoechst Ag, 6230 Frankfurt Forskolin, Verfahren zu dessen Gewinnung und diese Verbindung enthaltende pharmazeutische Präparate
DE2640275A1 (de) 1976-09-08 1978-03-09 Hoechst Ag Pharmakologisch wirksame substanz aus labiaten
DE2654796A1 (de) 1976-12-03 1978-06-08 Hoechst Ag Polyoxygenierte labdan-derivate
FR2460397A1 (fr) * 1979-07-05 1981-01-23 Ducellier & Cie Demarreur electrique pour moteurs a combustion interne notamment de vehicules automobiles
DE3581725D1 (de) * 1984-12-14 1991-03-14 Hoechst Roussel Pharma Aminoacyllabdane, verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung als arzneimittel.
DE3502685A1 (de) 1985-01-26 1986-09-04 Hoechst Ag, 6230 Frankfurt Forskolin, seine analoge und derivate, verfahren zu deren herstellung mittels mikrobieller umwandlungen und die anwendung dieser verbindungen als arzneimittel
US4639443A (en) * 1985-03-01 1987-01-27 Hoechst-Roussel Pharmaceuticals Inc. Labdane compounds, pharmaceutical compositions and use
ATE62683T1 (de) 1985-03-01 1991-05-15 Hoechst Roussel Pharma Labdanderivate, verfahren zu deren herstellung und deren verwendung als arzneimittel.
AU591196B2 (en) * 1985-11-15 1989-11-30 Nippon Kayaku Kabushiki Kaisha Novel forskolin derivatives

Also Published As

Publication number Publication date
DE3535086A1 (de) 1987-04-16
EP0217372A2 (de) 1987-04-08
EP0217372B1 (de) 1991-01-16
GR3001559T3 (en) 1992-11-23
DK468186A (da) 1987-04-03
ATE60054T1 (de) 1991-02-15
AU606036B2 (en) 1991-01-31
IN163242B (es) 1988-08-27
KR870004051A (ko) 1987-05-07
ZA867495B (en) 1987-05-27
HU203234B (en) 1991-06-28
PT83478B (pt) 1989-05-31
DK468186D0 (da) 1986-10-01
HUT46319A (en) 1988-10-28
PT83478A (de) 1986-11-01
IN164680B (es) 1989-05-06
EP0217372A3 (en) 1988-03-30
AU6327086A (en) 1987-04-09
IL80201A0 (en) 1986-12-31
DE3676922D1 (de) 1991-02-21
JPS6289677A (ja) 1987-04-24

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