DK468186A - Polyxygenerede labdan-derivater, deres fremstilling og anvendelse - Google Patents

Polyxygenerede labdan-derivater, deres fremstilling og anvendelse Download PDF

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Publication number
DK468186A
DK468186A DK468186A DK468186A DK468186A DK 468186 A DK468186 A DK 468186A DK 468186 A DK468186 A DK 468186A DK 468186 A DK468186 A DK 468186A DK 468186 A DK468186 A DK 468186A
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DK
Denmark
Prior art keywords
polyxygenerated
preparation
application
derivatives
labdan
Prior art date
Application number
DK468186A
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Danish (da)
English (en)
Other versions
DK468186D0 (da
Inventor
Yatendra Khandelwal
Ramanujam Rajgopalan
Alihussein Nomanbha Dohadwalla
Richard Helmut Rupp
Souza Noel John De
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK468186D0 publication Critical patent/DK468186D0/da
Publication of DK468186A publication Critical patent/DK468186A/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/92Naphthopyrans; Hydrogenated naphthopyrans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)
DK468186A 1985-10-02 1986-10-01 Polyxygenerede labdan-derivater, deres fremstilling og anvendelse DK468186A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853535086 DE3535086A1 (de) 1985-10-02 1985-10-02 Neue polyoxygenierte labdan-derivate, verfahren zu ihrer herstellung und ihre anwendung als medikamente

Publications (2)

Publication Number Publication Date
DK468186D0 DK468186D0 (da) 1986-10-01
DK468186A true DK468186A (da) 1987-04-03

Family

ID=6282512

Family Applications (1)

Application Number Title Priority Date Filing Date
DK468186A DK468186A (da) 1985-10-02 1986-10-01 Polyxygenerede labdan-derivater, deres fremstilling og anvendelse

Country Status (14)

Country Link
EP (1) EP0217372B1 (es)
JP (1) JPS6289677A (es)
KR (1) KR870004051A (es)
AT (1) ATE60054T1 (es)
AU (1) AU606036B2 (es)
DE (2) DE3535086A1 (es)
DK (1) DK468186A (es)
ES (1) ES2019863B3 (es)
GR (1) GR3001559T3 (es)
HU (1) HU203234B (es)
IL (1) IL80201A0 (es)
IN (2) IN163242B (es)
PT (1) PT83478B (es)
ZA (1) ZA867495B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3678736D1 (de) * 1985-03-01 1991-05-23 Hoechst Roussel Pharma Labdanderivate, verfahren zu deren herstellung und deren verwendung als arzneimittel.
US4963537A (en) * 1985-03-01 1990-10-16 Hoechst-Roussel Pharmaceuticals Inc. Labdane compounds, pharmaceutical compositions and use
JPS6310783A (ja) * 1985-11-15 1988-01-18 Nippon Kayaku Co Ltd 新規フオルスコリン誘導体
AU591196B2 (en) * 1985-11-15 1989-11-30 Nippon Kayaku Kabushiki Kaisha Novel forskolin derivatives
DE3623300A1 (de) * 1986-07-11 1988-01-21 Hoechst Ag 7-acyloxy-6-aminoacyloxypolyoxylabdane, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US4920146A (en) * 1986-12-29 1990-04-24 Hoechst Roussel Pharmaceuticals Inc. Carbamoyloxylabdane compounds useful in reducing intraocular pressure
US5646175A (en) * 1987-12-28 1997-07-08 Hoechst Marion Roussel, Inc. Carbamoyloxylabdane compounds
IN166900B (es) * 1987-06-03 1990-08-04 Hoechst India
JPH0684367B2 (ja) * 1987-06-29 1994-10-26 日本化薬株式会社 フオルスコリン誘導体の新規製造法
JP2504934B2 (ja) * 1987-06-29 1996-06-05 日本化薬株式会社 1,6,7−トリアシルフオルスコリン誘導体
US4902696A (en) * 1987-10-08 1990-02-20 Hoechst-Roussel Pharmaceuticals, Inc. Synergistic intraocular pressure lowering combinations
US5846992A (en) * 1987-10-08 1998-12-08 Hoechst Marion Roussel, Inc. Synergistic intraocular pressure lowering combinations
US4883793A (en) * 1988-05-09 1989-11-28 Hoechst-Roussel Pharmaceuticals Inc. Hydrazinocarbonyloxylabdanes for treating cardiac failure
EP0447962A1 (en) * 1990-03-17 1991-09-25 Hoechst Aktiengesellschaft Labdanes and process for their preparation
RU2034840C1 (ru) * 1990-07-24 1995-05-10 Хехст АГ СПОСОБ ПОЛУЧЕНИЯ ПРОИЗВОДНЫХ 6-бета-(3-ЗАМЕЩЕННОГО АМИНО)-ПРОПИОНИЛОКСИ-7-ДИАЦЕТИЛФОРСКОЛИНА ИЛИ ИХ ФАРМАЦЕВТИЧЕСКИ ПРИЕМЛЕМЫХ СОЛЕЙ
JP3557095B2 (ja) * 1998-04-20 2004-08-25 高砂香料工業株式会社 メラニン産生抑制剤

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2557784C2 (de) 1975-12-22 1986-04-17 Hoechst Ag, 6230 Frankfurt Forskolin, Verfahren zu dessen Gewinnung und diese Verbindung enthaltende pharmazeutische Präparate
DE2640275A1 (de) 1976-09-08 1978-03-09 Hoechst Ag Pharmakologisch wirksame substanz aus labiaten
DE2654796A1 (de) * 1976-12-03 1978-06-08 Hoechst Ag Polyoxygenierte labdan-derivate
FR2460397A1 (fr) * 1979-07-05 1981-01-23 Ducellier & Cie Demarreur electrique pour moteurs a combustion interne notamment de vehicules automobiles
EP0191166B1 (en) * 1984-12-14 1991-02-06 Hoechst-Roussel Pharmaceuticals Incorporated Aminoacyllabdanes, a process and intermediates for their preparation and their use as medicaments
DE3502685A1 (de) 1985-01-26 1986-09-04 Hoechst Ag, 6230 Frankfurt Forskolin, seine analoge und derivate, verfahren zu deren herstellung mittels mikrobieller umwandlungen und die anwendung dieser verbindungen als arzneimittel
US4639443A (en) * 1985-03-01 1987-01-27 Hoechst-Roussel Pharmaceuticals Inc. Labdane compounds, pharmaceutical compositions and use
DE3678736D1 (de) * 1985-03-01 1991-05-23 Hoechst Roussel Pharma Labdanderivate, verfahren zu deren herstellung und deren verwendung als arzneimittel.
AU591196B2 (en) * 1985-11-15 1989-11-30 Nippon Kayaku Kabushiki Kaisha Novel forskolin derivatives

Also Published As

Publication number Publication date
JPS6289677A (ja) 1987-04-24
ES2019863B3 (es) 1991-07-16
DE3535086A1 (de) 1987-04-16
EP0217372A2 (de) 1987-04-08
ZA867495B (en) 1987-05-27
GR3001559T3 (en) 1992-11-23
ATE60054T1 (de) 1991-02-15
HU203234B (en) 1991-06-28
AU606036B2 (en) 1991-01-31
HUT46319A (en) 1988-10-28
IL80201A0 (en) 1986-12-31
KR870004051A (ko) 1987-05-07
EP0217372A3 (en) 1988-03-30
DE3676922D1 (de) 1991-02-21
PT83478B (pt) 1989-05-31
PT83478A (de) 1986-11-01
IN164680B (es) 1989-05-06
EP0217372B1 (de) 1991-01-16
AU6327086A (en) 1987-04-09
IN163242B (es) 1988-08-27
DK468186D0 (da) 1986-10-01

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