DE3678086D1 - Rhizoxinderivate, ihre herstellung und pharmazeutische verwendung. - Google Patents

Rhizoxinderivate, ihre herstellung und pharmazeutische verwendung.

Info

Publication number
DE3678086D1
DE3678086D1 DE8686301465T DE3678086T DE3678086D1 DE 3678086 D1 DE3678086 D1 DE 3678086D1 DE 8686301465 T DE8686301465 T DE 8686301465T DE 3678086 T DE3678086 T DE 3678086T DE 3678086 D1 DE3678086 D1 DE 3678086D1
Authority
DE
Germany
Prior art keywords
derivatives
rhizoxine
production
pharmaceutical use
rhizoxin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686301465T
Other languages
English (en)
Inventor
Shigenobu Okuda
Shigeo Iwasaki
Michio Namikoshi
Masao Arakawa
Fusaaki Shimizu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Application granted granted Critical
Publication of DE3678086D1 publication Critical patent/DE3678086D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/14—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
DE8686301465T 1985-02-28 1986-02-28 Rhizoxinderivate, ihre herstellung und pharmazeutische verwendung. Expired - Fee Related DE3678086D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3939985 1985-02-28

Publications (1)

Publication Number Publication Date
DE3678086D1 true DE3678086D1 (de) 1991-04-18

Family

ID=12551912

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686301465T Expired - Fee Related DE3678086D1 (de) 1985-02-28 1986-02-28 Rhizoxinderivate, ihre herstellung und pharmazeutische verwendung.

Country Status (8)

Country Link
US (1) US4791128A (de)
EP (1) EP0218310B1 (de)
JP (1) JPS6287A (de)
CN (1) CN1009554B (de)
AT (1) ATE61590T1 (de)
CA (1) CA1271763A (de)
DE (1) DE3678086D1 (de)
ES (1) ES8705449A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07116198B2 (ja) * 1987-04-02 1995-12-13 三共株式会社 リゾキシン誘導体
JPS63295447A (ja) * 1987-05-27 1988-12-01 Matsushita Electric Ind Co Ltd 光学ガラス素子の製造方法
US5352689A (en) * 1988-07-06 1994-10-04 Sankyo Company, Limited Rhizoxin derivatives and their use as anti-tumor agents
CA1334757C (en) * 1988-07-06 1995-03-14 Masakatsu Kaneko Rhizoxin derivatives and their use as anti-tumor agents
WO1993021918A1 (en) * 1992-04-28 1993-11-11 Sankyo Company, Limited Fat emulsion containing fatty acid ester of rhizoxin
DE102012000956A1 (de) * 2011-06-21 2012-12-27 Leibniz-Institut Für Naturstoff-Forschung Und Infektionsbiologie Neue Rhizoxinderivate

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6084220A (ja) * 1983-10-17 1985-05-13 Norin Suisansyo Nogyo Kankyo Gijutsu Kenkyusho 植物病原菌リゾ−プス・キネンシスの代謝産物リゾキシンを有効成分とする抗腫瘍剤

Also Published As

Publication number Publication date
CN1009554B (zh) 1990-09-12
CN86102020A (zh) 1986-10-01
CA1271763A (en) 1990-07-17
ES8705449A1 (es) 1987-05-01
JPS6287A (ja) 1987-01-06
EP0218310A2 (de) 1987-04-15
EP0218310A3 (en) 1987-12-23
US4791128A (en) 1988-12-13
ES552563A0 (es) 1987-05-01
JPH0474356B2 (de) 1992-11-26
ATE61590T1 (de) 1991-03-15
EP0218310B1 (de) 1991-03-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee