ES2019163A6 - Procedimiento para preparar derivados de imidazol. - Google Patents

Procedimiento para preparar derivados de imidazol.

Info

Publication number
ES2019163A6
ES2019163A6 ES8903313A ES8903313A ES2019163A6 ES 2019163 A6 ES2019163 A6 ES 2019163A6 ES 8903313 A ES8903313 A ES 8903313A ES 8903313 A ES8903313 A ES 8903313A ES 2019163 A6 ES2019163 A6 ES 2019163A6
Authority
ES
Spain
Prior art keywords
formula
procedure
csi1
rbs1
pyridyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES8903313A
Other languages
English (en)
Spanish (es)
Inventor
Nigel S Watson
Chuen Chan
Barry C Ross
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888823191A external-priority patent/GB8823191D0/en
Priority claimed from GB888823192A external-priority patent/GB8823192D0/en
Priority claimed from GB898902847A external-priority patent/GB8902847D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ES2019163A6 publication Critical patent/ES2019163A6/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES8903313A 1988-10-03 1989-10-02 Procedimiento para preparar derivados de imidazol. Expired - Fee Related ES2019163A6 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB888823191A GB8823191D0 (en) 1988-10-03 1988-10-03 Chemical compounds
GB888823192A GB8823192D0 (en) 1988-10-03 1988-10-03 Chemical compounds
GB898902847A GB8902847D0 (en) 1989-02-09 1989-02-09 Chemical compounds

Publications (1)

Publication Number Publication Date
ES2019163A6 true ES2019163A6 (es) 1991-06-01

Family

ID=27264106

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8903313A Expired - Fee Related ES2019163A6 (es) 1988-10-03 1989-10-02 Procedimiento para preparar derivados de imidazol.

Country Status (19)

Country Link
US (2) US5013749A (OSRAM)
JP (1) JPH02188571A (OSRAM)
KR (1) KR900006297A (OSRAM)
AU (1) AU628862B2 (OSRAM)
BE (1) BE1003007A3 (OSRAM)
CH (1) CH680442A5 (OSRAM)
DE (1) DE3932887A1 (OSRAM)
DK (1) DK483689A (OSRAM)
ES (1) ES2019163A6 (OSRAM)
FI (1) FI894648A7 (OSRAM)
FR (1) FR2637183A1 (OSRAM)
GB (1) GB2223224B (OSRAM)
GR (1) GR890100634A (OSRAM)
IT (1) IT1237470B (OSRAM)
LU (1) LU87600A1 (OSRAM)
NL (1) NL8902441A (OSRAM)
NO (1) NO893909L (OSRAM)
PT (1) PT91878B (OSRAM)
SE (1) SE8903226L (OSRAM)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3913725A1 (de) * 1989-04-26 1990-10-31 Basf Ag 1-halogenvinyl-azole und diese enthaltende fungizide und wachstumsregulatoren
EP0422895A1 (en) * 1989-10-10 1991-04-17 Glaxo Group Limited Chemical compounds
PL361097A1 (en) * 2000-10-12 2004-09-20 Nissan Chemical Industries, Ltd. Preventives and remedies for complications of diabetes
IL158300A0 (en) * 2001-04-27 2004-05-12 Bristol Myers Squibb Co Bisarylimidazol derivatives and pharmaceutical compositions containing the same
KR20060133013A (ko) * 2004-04-16 2006-12-22 워너-램버트 캄파니 엘엘씨 신규 이미다졸
US20050282883A1 (en) * 2004-04-29 2005-12-22 John Griffin Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase
US7163945B2 (en) * 2004-04-29 2007-01-16 Pharmix Corp. Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase
US20060084695A1 (en) * 2004-04-29 2006-04-20 John Griffin Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase
US7199126B2 (en) 2004-04-29 2007-04-03 Pharmix Corporation Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase
US7183285B2 (en) * 2004-04-29 2007-02-27 Pharmix Corp. Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase
US20050272770A1 (en) * 2004-04-29 2005-12-08 John Griffin Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase
WO2005115397A2 (en) * 2004-04-29 2005-12-08 Pharmix Corporation Compositions and treatments for modulating kinase and/or hmg-coa reductase
US20060111436A1 (en) * 2004-11-23 2006-05-25 John Griffin Compositions and treatments for modulating kinase and/or HMG-CoA reductase
US8372877B2 (en) 2010-04-16 2013-02-12 Cumberland Pharmaceuticals Stabilized statin formulations
EP2626069A4 (en) 2010-10-06 2014-03-19 Univ Tokyo Prophylactic and/or therapeutic agent against lymphedema

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4231938A (en) * 1979-06-15 1980-11-04 Merck & Co., Inc. Hypocholesteremic fermentation products and process of preparation
US4647576A (en) * 1984-09-24 1987-03-03 Warner-Lambert Company Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis
US4668794A (en) * 1985-05-22 1987-05-26 Sandoz Pharm. Corp. Intermediate imidazole acrolein analogs
HUT48208A (en) * 1985-10-25 1989-05-29 Sandoz Ag Process for producing heterocyclic analogues of mevalolactone derivatives and pharmaceutical compositions comprising such compounds
EP0244364A3 (en) * 1986-04-30 1992-04-01 Sandoz Ag Preparation of olefinic compounds
DE3800785A1 (de) * 1988-01-09 1989-07-20 Hoechst Ag Substituierte 7-(pyridazin-5-yl)-3,5-dihydroxyheptan(en)- saeuren, ihre entsprechenden (delta)-lactone bzw. derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte
NO890522L (no) * 1988-02-25 1989-08-28 Bayer Ag Substituerte imidazolinoner og imidazolinthioner.

Also Published As

Publication number Publication date
AU4243189A (en) 1990-04-05
PT91878A (pt) 1990-04-30
AU628862B2 (en) 1992-09-24
CH680442A5 (OSRAM) 1992-08-31
KR900006297A (ko) 1990-05-07
DK483689A (da) 1990-04-04
NL8902441A (nl) 1990-05-01
DK483689D0 (da) 1989-10-02
SE8903226L (sv) 1990-04-04
FI894648A0 (fi) 1989-10-02
LU87600A1 (fr) 1990-05-15
FR2637183A1 (fr) 1990-04-06
DE3932887A1 (de) 1990-04-05
IT8948424A0 (it) 1989-10-02
GB2223224B (en) 1992-01-08
NO893909D0 (no) 1989-10-02
FI894648L (fi) 1990-04-04
SE8903226D0 (sv) 1989-10-02
BE1003007A3 (fr) 1991-10-22
IT1237470B (it) 1993-06-07
NO893909L (no) 1990-04-04
US5120848A (en) 1992-06-09
PT91878B (pt) 1995-05-31
JPH02188571A (ja) 1990-07-24
GR890100634A (el) 1990-11-29
FI894648A7 (fi) 1990-04-04
US5013749A (en) 1991-05-07
GB2223224A (en) 1990-04-04
GB8922212D0 (en) 1989-11-15
IT8948424A1 (it) 1991-04-02

Similar Documents

Publication Publication Date Title
ES2019163A6 (es) Procedimiento para preparar derivados de imidazol.
ES8203883A1 (es) Un procedimiento para la preparacion de derivados de imida- zol
MY102774A (en) Process for the preparation of 1-triazolylethyl ether derivatives
ES8401754A1 (es) "procedimiento de preparar derivados sulfonato".
ES8603470A1 (es) Procedimiento de obtencion de compuestos de 1-aril-2-(3-(4-trifluormetilestiril)-1,2,4-triazol-1-il)-1-c 1,2,4,-triazol-1-il-metil) etanol de efecto antifugal.
SE7512643L (sv) Triazolderivat
ES8502670A1 (es) Procedimiento para preparar derivados de 3-bencilidenalcanfor
SE7709016L (sv) 1-(2-aryl-2-r-etyl)-1h-1,2,4-triazoler
ES8604179A1 (es) Procedimiento para la preparacion de nuevos derivados tiazo-lidinicos
IT1035209B (it) Apparecchio di acoquisizione di bersasli mediante fascio laser
ES8105248A1 (es) Procedimiento para preparar derivados de trifenilalqueno
DK98183D0 (da) Fremgangsmade til fremstilling af 1,2,4-triazol-forbindelser eller farmaceutisk acceptable syreadditionssalte deraf
ES357368A1 (es) Procedimiento para la preparacion de derivados de acido ci-clohexilpentadienoico.
ES466116A1 (es) Procedimiento para preparar derivados de imidazol o 1,2,4- triazol
ES8507484A1 (es) Procedimiento de producir compuestos beta-lactamicos y similares
ES8301200A1 (es) Procedimiento para la preparacion de derivados de ciclohexe-no
ES8603243A1 (es) Un procedimiento para la preparacion de agentes antifungicos de triazol.
GB1494741A (en) Fog-inhibitors for silver halide photography
ES8205204A1 (es) Un procedimiento para la preparacion de derivados de imida- zol
ES245415A1 (es) Procedimiento para la preparacion de derivados heterociclicos de hidrazina
ES368406A1 (es) Procedimiento para la obtencion de un medio fungicida a ba-se de esteres fosforicos.
ES474785A1 (es) Un procedimiento para la preparacion de compuestos derivadosde 1-(naftiletil)imidazol
ES8505668A1 (es) Un procedimiento para preparar un derivado de imidazolinona
ES450371A1 (es) Un procedimiento para la preparacion de un compuesto de 4- (hidioximetil) midazol.
IT7826317A0 (it) Composizioni oftalmiche contenenti derivati di acido isochinoin-acetico.

Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2009-10-02

FD1A Patent lapsed

Effective date: 20010201