IT1237470B - Derivati di imidazolo, procedimenti per produrli e composizioni farmaceutiche che li contengono - Google Patents

Derivati di imidazolo, procedimenti per produrli e composizioni farmaceutiche che li contengono

Info

Publication number
IT1237470B
IT1237470B IT04842489A IT4842489A IT1237470B IT 1237470 B IT1237470 B IT 1237470B IT 04842489 A IT04842489 A IT 04842489A IT 4842489 A IT4842489 A IT 4842489A IT 1237470 B IT1237470 B IT 1237470B
Authority
IT
Italy
Prior art keywords
procedures
produce
pharmaceutical compositions
compositions containing
imidazole derivatives
Prior art date
Application number
IT04842489A
Other languages
English (en)
Other versions
IT8948424A0 (it
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888823192A external-priority patent/GB8823192D0/en
Priority claimed from GB888823191A external-priority patent/GB8823191D0/en
Priority claimed from GB898902847A external-priority patent/GB8902847D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of IT8948424A0 publication Critical patent/IT8948424A0/it
Application granted granted Critical
Publication of IT1237470B publication Critical patent/IT1237470B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IT04842489A 1988-10-03 1989-10-02 Derivati di imidazolo, procedimenti per produrli e composizioni farmaceutiche che li contengono IT1237470B (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB888823192A GB8823192D0 (en) 1988-10-03 1988-10-03 Chemical compounds
GB888823191A GB8823191D0 (en) 1988-10-03 1988-10-03 Chemical compounds
GB898902847A GB8902847D0 (en) 1989-02-09 1989-02-09 Chemical compounds

Publications (2)

Publication Number Publication Date
IT8948424A0 IT8948424A0 (it) 1989-10-02
IT1237470B true IT1237470B (it) 1993-06-07

Family

ID=27264106

Family Applications (1)

Application Number Title Priority Date Filing Date
IT04842489A IT1237470B (it) 1988-10-03 1989-10-02 Derivati di imidazolo, procedimenti per produrli e composizioni farmaceutiche che li contengono

Country Status (19)

Country Link
US (2) US5013749A (it)
JP (1) JPH02188571A (it)
KR (1) KR900006297A (it)
AU (1) AU628862B2 (it)
BE (1) BE1003007A3 (it)
CH (1) CH680442A5 (it)
DE (1) DE3932887A1 (it)
DK (1) DK483689A (it)
ES (1) ES2019163A6 (it)
FI (1) FI894648A (it)
FR (1) FR2637183A1 (it)
GB (1) GB2223224B (it)
GR (1) GR890100634A (it)
IT (1) IT1237470B (it)
LU (1) LU87600A1 (it)
NL (1) NL8902441A (it)
NO (1) NO893909L (it)
PT (1) PT91878B (it)
SE (1) SE8903226L (it)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3913725A1 (de) * 1989-04-26 1990-10-31 Basf Ag 1-halogenvinyl-azole und diese enthaltende fungizide und wachstumsregulatoren
IE903606A1 (en) * 1989-10-10 1991-04-24 Glaxo Group Ltd Chemical compounds
RU2003113328A (ru) * 2000-10-12 2004-09-10 Ниссан Кемикал Индастриз, Лтд (Jp) Профилактическое и терапевтическое средство для лечения осложнений, связанных с диабетом
IL158300A0 (en) * 2001-04-27 2004-05-12 Bristol Myers Squibb Co Bisarylimidazol derivatives and pharmaceutical compositions containing the same
BRPI0509926A (pt) * 2004-04-16 2007-09-18 Warner Lambert Co imidazóis
US7199126B2 (en) 2004-04-29 2007-04-03 Pharmix Corporation Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase
US20060084695A1 (en) * 2004-04-29 2006-04-20 John Griffin Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase
US20050272770A1 (en) * 2004-04-29 2005-12-08 John Griffin Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase
US7163945B2 (en) * 2004-04-29 2007-01-16 Pharmix Corp. Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase
US20050282883A1 (en) * 2004-04-29 2005-12-22 John Griffin Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase
JP2007535558A (ja) * 2004-04-29 2007-12-06 ファーミックス コーポレイション キナーゼおよび／またはｈｍｇ−ｃｏａレダクターゼを阻害するための組成物および処置
US7183285B2 (en) * 2004-04-29 2007-02-27 Pharmix Corp. Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase
US20060111436A1 (en) * 2004-11-23 2006-05-25 John Griffin Compositions and treatments for modulating kinase and/or HMG-CoA reductase
US8372877B2 (en) 2010-04-16 2013-02-12 Cumberland Pharmaceuticals Stabilized statin formulations
KR20130137623A (ko) 2010-10-06 2013-12-17 고쿠리츠다이가쿠호우진 도쿄다이가쿠 림프 부종 예방 치료제

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4231938A (en) * 1979-06-15 1980-11-04 Merck & Co., Inc. Hypocholesteremic fermentation products and process of preparation
US4647576A (en) * 1984-09-24 1987-03-03 Warner-Lambert Company Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis
US4668794A (en) * 1985-05-22 1987-05-26 Sandoz Pharm. Corp. Intermediate imidazole acrolein analogs
EP0221025A1 (en) * 1985-10-25 1987-05-06 Sandoz Ag Heterocyclic analogs of mevalonolactone and derivatives thereof, processes for their production and their use as pharmaceuticals
EP0244364A3 (en) * 1986-04-30 1992-04-01 Sandoz Ag Preparation of olefinic compounds
DE3800785A1 (de) * 1988-01-09 1989-07-20 Hoechst Ag Substituierte 7-(pyridazin-5-yl)-3,5-dihydroxyheptan(en)- saeuren, ihre entsprechenden (delta)-lactone bzw. derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte
NO890522L (no) * 1988-02-25 1989-08-28 Bayer Ag Substituerte imidazolinoner og imidazolinthioner.

Also Published As

Publication number Publication date
IT8948424A0 (it) 1989-10-02
ES2019163A6 (es) 1991-06-01
US5120848A (en) 1992-06-09
NO893909L (no) 1990-04-04
GR890100634A (el) 1990-11-29
AU628862B2 (en) 1992-09-24
FR2637183A1 (fr) 1990-04-06
NL8902441A (nl) 1990-05-01
FI894648A0 (fi) 1989-10-02
PT91878A (pt) 1990-04-30
PT91878B (pt) 1995-05-31
GB8922212D0 (en) 1989-11-15
DK483689A (da) 1990-04-04
SE8903226D0 (sv) 1989-10-02
DE3932887A1 (de) 1990-04-05
CH680442A5 (it) 1992-08-31
SE8903226L (sv) 1990-04-04
JPH02188571A (ja) 1990-07-24
DK483689D0 (da) 1989-10-02
FI894648A (fi) 1990-04-04
NO893909D0 (no) 1989-10-02
KR900006297A (ko) 1990-05-07
GB2223224B (en) 1992-01-08
LU87600A1 (fr) 1990-05-15
US5013749A (en) 1991-05-07
GB2223224A (en) 1990-04-04
BE1003007A3 (fr) 1991-10-22
AU4243189A (en) 1990-04-05

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Legal Events

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0001 Granted