IT1237470B - Derivati di imidazolo, procedimenti per produrli e composizioni farmaceutiche che li contengono - Google Patents

Derivati di imidazolo, procedimenti per produrli e composizioni farmaceutiche che li contengono

Info

Publication number
IT1237470B
IT1237470B IT04842489A IT4842489A IT1237470B IT 1237470 B IT1237470 B IT 1237470B IT 04842489 A IT04842489 A IT 04842489A IT 4842489 A IT4842489 A IT 4842489A IT 1237470 B IT1237470 B IT 1237470B
Authority
IT
Italy
Prior art keywords
procedures
produce
pharmaceutical compositions
compositions containing
imidazole derivatives
Prior art date
Application number
IT04842489A
Other languages
English (en)
Other versions
IT8948424A1 (it
IT8948424A0 (it
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888823191A external-priority patent/GB8823191D0/en
Priority claimed from GB888823192A external-priority patent/GB8823192D0/en
Priority claimed from GB898902847A external-priority patent/GB8902847D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of IT8948424A0 publication Critical patent/IT8948424A0/it
Publication of IT8948424A1 publication Critical patent/IT8948424A1/it
Application granted granted Critical
Publication of IT1237470B publication Critical patent/IT1237470B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IT04842489A 1988-10-03 1989-10-02 Derivati di imidazolo, procedimenti per produrli e composizioni farmaceutiche che li contengono IT1237470B (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB888823191A GB8823191D0 (en) 1988-10-03 1988-10-03 Chemical compounds
GB888823192A GB8823192D0 (en) 1988-10-03 1988-10-03 Chemical compounds
GB898902847A GB8902847D0 (en) 1989-02-09 1989-02-09 Chemical compounds

Publications (3)

Publication Number Publication Date
IT8948424A0 IT8948424A0 (it) 1989-10-02
IT8948424A1 IT8948424A1 (it) 1991-04-02
IT1237470B true IT1237470B (it) 1993-06-07

Family

ID=27264106

Family Applications (1)

Application Number Title Priority Date Filing Date
IT04842489A IT1237470B (it) 1988-10-03 1989-10-02 Derivati di imidazolo, procedimenti per produrli e composizioni farmaceutiche che li contengono

Country Status (19)

Country Link
US (2) US5013749A (it)
JP (1) JPH02188571A (it)
KR (1) KR900006297A (it)
AU (1) AU628862B2 (it)
BE (1) BE1003007A3 (it)
CH (1) CH680442A5 (it)
DE (1) DE3932887A1 (it)
DK (1) DK483689A (it)
ES (1) ES2019163A6 (it)
FI (1) FI894648A7 (it)
FR (1) FR2637183A1 (it)
GB (1) GB2223224B (it)
GR (1) GR890100634A (it)
IT (1) IT1237470B (it)
LU (1) LU87600A1 (it)
NL (1) NL8902441A (it)
NO (1) NO893909L (it)
PT (1) PT91878B (it)
SE (1) SE8903226L (it)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3913725A1 (de) * 1989-04-26 1990-10-31 Basf Ag 1-halogenvinyl-azole und diese enthaltende fungizide und wachstumsregulatoren
JPH03184961A (ja) * 1989-10-10 1991-08-12 Glaxo Group Ltd 化合物
DE60135000D1 (de) * 2000-10-12 2008-09-04 Nissan Chemical Ind Ltd Wirkstoffe zur vorbeugung und behandlung von komplikationen im zusammenhang mit diabetes
WO2002087569A1 (en) * 2001-04-27 2002-11-07 Bristol-Myers Squibb Company Bisarylimidazolyl fatty acid amide hydrolase inhibitors
AP2006003766A0 (en) * 2004-04-16 2006-10-31 Warner Lambert Co Novel imidazoles
US20060084695A1 (en) * 2004-04-29 2006-04-20 John Griffin Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase
WO2006028524A2 (en) * 2004-04-29 2006-03-16 Pharmix Corporation Compositions and treatments for inhibiting kinase and/or hmg-coa reductase
US7163945B2 (en) * 2004-04-29 2007-01-16 Pharmix Corp. Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase
US7199126B2 (en) * 2004-04-29 2007-04-03 Pharmix Corporation Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase
US20050272770A1 (en) * 2004-04-29 2005-12-08 John Griffin Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase
US20050282883A1 (en) * 2004-04-29 2005-12-22 John Griffin Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase
US7183285B2 (en) * 2004-04-29 2007-02-27 Pharmix Corp. Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase
US20060111436A1 (en) * 2004-11-23 2006-05-25 John Griffin Compositions and treatments for modulating kinase and/or HMG-CoA reductase
US8372877B2 (en) 2010-04-16 2013-02-12 Cumberland Pharmaceuticals Stabilized statin formulations
US20130210860A1 (en) 2010-10-06 2013-08-15 Kowa Co., Ltd. Prophylactic and/or therapeutic agent against lymphedema

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4231938A (en) * 1979-06-15 1980-11-04 Merck & Co., Inc. Hypocholesteremic fermentation products and process of preparation
US4647576A (en) * 1984-09-24 1987-03-03 Warner-Lambert Company Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis
US4668794A (en) * 1985-05-22 1987-05-26 Sandoz Pharm. Corp. Intermediate imidazole acrolein analogs
KR900001212B1 (ko) * 1985-10-25 1990-02-28 산도즈 파마슈티칼스 코오포레이숀 메바로노락톤 및 그것의 유도체의 헤테로사이클릭 유사체 및 그것의 생산방법 및 약학적인 그것의 용도
JPS6322056A (ja) * 1986-04-30 1988-01-29 サンド・アクチエンゲゼルシヤフト オレフイン性化合物の製造法
DE3800785A1 (de) * 1988-01-09 1989-07-20 Hoechst Ag Substituierte 7-(pyridazin-5-yl)-3,5-dihydroxyheptan(en)- saeuren, ihre entsprechenden (delta)-lactone bzw. derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte
NO890522L (no) * 1988-02-25 1989-08-28 Bayer Ag Substituerte imidazolinoner og imidazolinthioner.

Also Published As

Publication number Publication date
SE8903226L (sv) 1990-04-04
KR900006297A (ko) 1990-05-07
GB2223224B (en) 1992-01-08
GB8922212D0 (en) 1989-11-15
CH680442A5 (it) 1992-08-31
DK483689D0 (da) 1989-10-02
IT8948424A1 (it) 1991-04-02
ES2019163A6 (es) 1991-06-01
FR2637183A1 (fr) 1990-04-06
SE8903226D0 (sv) 1989-10-02
GR890100634A (el) 1990-11-29
US5120848A (en) 1992-06-09
BE1003007A3 (fr) 1991-10-22
LU87600A1 (fr) 1990-05-15
PT91878B (pt) 1995-05-31
US5013749A (en) 1991-05-07
FI894648L (fi) 1990-04-04
AU628862B2 (en) 1992-09-24
NL8902441A (nl) 1990-05-01
PT91878A (pt) 1990-04-30
FI894648A0 (fi) 1989-10-02
DK483689A (da) 1990-04-04
NO893909L (no) 1990-04-04
DE3932887A1 (de) 1990-04-05
FI894648A7 (fi) 1990-04-04
JPH02188571A (ja) 1990-07-24
GB2223224A (en) 1990-04-04
IT8948424A0 (it) 1989-10-02
NO893909D0 (no) 1989-10-02
AU4243189A (en) 1990-04-05

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Legal Events

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