GR890100634A - Παραγωγα ιμιδαζολης. - Google Patents
Παραγωγα ιμιδαζολης.Info
- Publication number
- GR890100634A GR890100634A GR890100634A GR890100634A GR890100634A GR 890100634 A GR890100634 A GR 890100634A GR 890100634 A GR890100634 A GR 890100634A GR 890100634 A GR890100634 A GR 890100634A GR 890100634 A GR890100634 A GR 890100634A
- Authority
- GR
- Greece
- Prior art keywords
- imidazole derivatives
- imidazole
- bile
- reductase
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Ωρισμένα νέα παράγωγα ιμιδαζόλης Ν-υποκατεστημένα δια μιας βινυλομάδος η οποία φέρει η ιδία ένα παράγωγον μεβαλονικού οξέος ή την αντίστοιχην λακτόνην είναι παρεμποδισταί της ρεδουκτάσης (χημικός τύπος) και είναι χρήσιμα δια την ελλάτωσι των περιεκτικοτήτων χοληστερίνης εις το πλάσμα του αίματος. ω
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB888823191A GB8823191D0 (en) | 1988-10-03 | 1988-10-03 | Chemical compounds |
GB888823192A GB8823192D0 (en) | 1988-10-03 | 1988-10-03 | Chemical compounds |
GB898902847A GB8902847D0 (en) | 1989-02-09 | 1989-02-09 | Chemical compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
GR890100634A true GR890100634A (el) | 1990-11-29 |
Family
ID=27264106
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR890100634A GR890100634A (el) | 1988-10-03 | 1989-10-03 | Παραγωγα ιμιδαζολης. |
Country Status (19)
Country | Link |
---|---|
US (2) | US5013749A (el) |
JP (1) | JPH02188571A (el) |
KR (1) | KR900006297A (el) |
AU (1) | AU628862B2 (el) |
BE (1) | BE1003007A3 (el) |
CH (1) | CH680442A5 (el) |
DE (1) | DE3932887A1 (el) |
DK (1) | DK483689A (el) |
ES (1) | ES2019163A6 (el) |
FI (1) | FI894648A (el) |
FR (1) | FR2637183A1 (el) |
GB (1) | GB2223224B (el) |
GR (1) | GR890100634A (el) |
IT (1) | IT1237470B (el) |
LU (1) | LU87600A1 (el) |
NL (1) | NL8902441A (el) |
NO (1) | NO893909L (el) |
PT (1) | PT91878B (el) |
SE (1) | SE8903226L (el) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3913725A1 (de) * | 1989-04-26 | 1990-10-31 | Basf Ag | 1-halogenvinyl-azole und diese enthaltende fungizide und wachstumsregulatoren |
CA2027179A1 (en) * | 1989-10-10 | 1991-04-11 | Barry C. Ross | Chemical compounds |
CN1230173C (zh) * | 2000-10-12 | 2005-12-07 | 日产化学工业株式会社 | 糖尿病合并症预防及治疗剂 |
MXPA03009850A (es) * | 2001-04-27 | 2004-02-12 | Bristol Myers Squibb Co | Inhibidores de bisarilimidazolil de hidrolasa de amida del acido graso. |
EA200601678A1 (ru) * | 2004-04-16 | 2007-04-27 | УОРНЕР-ЛАМБЕРТ КОМПАНИ Эл-Эл-Си | Новые имидазолы |
US7199126B2 (en) * | 2004-04-29 | 2007-04-03 | Pharmix Corporation | Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase |
US20050282883A1 (en) * | 2004-04-29 | 2005-12-22 | John Griffin | Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase |
US20060084695A1 (en) * | 2004-04-29 | 2006-04-20 | John Griffin | Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase |
US7183285B2 (en) * | 2004-04-29 | 2007-02-27 | Pharmix Corp. | Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase |
US20050272770A1 (en) * | 2004-04-29 | 2005-12-08 | John Griffin | Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase |
US7163945B2 (en) * | 2004-04-29 | 2007-01-16 | Pharmix Corp. | Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase |
EP1755607A2 (en) * | 2004-04-29 | 2007-02-28 | Pharmix Corporation | Compositions and treatments for inhibiting kinase and/or hmg-coa reductase |
US20060111436A1 (en) * | 2004-11-23 | 2006-05-25 | John Griffin | Compositions and treatments for modulating kinase and/or HMG-CoA reductase |
US8372877B2 (en) | 2010-04-16 | 2013-02-12 | Cumberland Pharmaceuticals | Stabilized statin formulations |
EP2626069A4 (en) | 2010-10-06 | 2014-03-19 | Univ Tokyo | A MEDICINAL PRODUCT FOR THE PREVENTION AND TREATMENT OF A DERY LYMPH |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1986007054A1 (en) * | 1985-05-22 | 1986-12-04 | Sandoz Ag | Imidazole analogs of mevalonolactone and derivatives thereof |
US4647576A (en) * | 1984-09-24 | 1987-03-03 | Warner-Lambert Company | Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis |
EP0221025A1 (en) * | 1985-10-25 | 1987-05-06 | Sandoz Ag | Heterocyclic analogs of mevalonolactone and derivatives thereof, processes for their production and their use as pharmaceuticals |
EP0244364A2 (en) * | 1986-04-30 | 1987-11-04 | Sandoz Ag | Preparation of olefinic compounds |
EP0324347A2 (de) * | 1988-01-09 | 1989-07-19 | Hoechst Aktiengesellschaft | Neue 3,5-Dihydroxycarbonsäuren und deren Derivate, Verfahren zu ihrer Herstellung, ihre Verwendung als Arzneimittel, pharmazeutische Präparate und Zwischenprodukte |
EP0334014A2 (de) * | 1988-02-25 | 1989-09-27 | Bayer Ag | Substituierte Imidazolinone und Imidazolinthione |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4231938A (en) * | 1979-06-15 | 1980-11-04 | Merck & Co., Inc. | Hypocholesteremic fermentation products and process of preparation |
-
1989
- 1989-10-02 DK DK483689A patent/DK483689A/da not_active Application Discontinuation
- 1989-10-02 NO NO89893909A patent/NO893909L/no unknown
- 1989-10-02 NL NL8902441A patent/NL8902441A/nl not_active Application Discontinuation
- 1989-10-02 US US07/415,917 patent/US5013749A/en not_active Expired - Fee Related
- 1989-10-02 AU AU42431/89A patent/AU628862B2/en not_active Ceased
- 1989-10-02 BE BE8901048A patent/BE1003007A3/fr not_active IP Right Cessation
- 1989-10-02 ES ES8903313A patent/ES2019163A6/es not_active Expired - Fee Related
- 1989-10-02 LU LU87600A patent/LU87600A1/fr unknown
- 1989-10-02 JP JP1257612A patent/JPH02188571A/ja active Pending
- 1989-10-02 PT PT91878A patent/PT91878B/pt not_active IP Right Cessation
- 1989-10-02 DE DE3932887A patent/DE3932887A1/de not_active Withdrawn
- 1989-10-02 FI FI894648A patent/FI894648A/fi not_active IP Right Cessation
- 1989-10-02 IT IT04842489A patent/IT1237470B/it active IP Right Grant
- 1989-10-02 CH CH3584/89A patent/CH680442A5/de not_active IP Right Cessation
- 1989-10-02 FR FR8912856A patent/FR2637183A1/fr active Pending
- 1989-10-02 SE SE8903226A patent/SE8903226L/xx not_active Application Discontinuation
- 1989-10-03 GB GB8922212A patent/GB2223224B/en not_active Expired - Fee Related
- 1989-10-03 GR GR890100634A patent/GR890100634A/el unknown
- 1989-10-04 KR KR1019890014335A patent/KR900006297A/ko not_active Application Discontinuation
-
1991
- 1991-01-09 US US07/639,184 patent/US5120848A/en not_active Expired - Fee Related
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4647576A (en) * | 1984-09-24 | 1987-03-03 | Warner-Lambert Company | Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis |
WO1986007054A1 (en) * | 1985-05-22 | 1986-12-04 | Sandoz Ag | Imidazole analogs of mevalonolactone and derivatives thereof |
EP0221025A1 (en) * | 1985-10-25 | 1987-05-06 | Sandoz Ag | Heterocyclic analogs of mevalonolactone and derivatives thereof, processes for their production and their use as pharmaceuticals |
EP0244364A2 (en) * | 1986-04-30 | 1987-11-04 | Sandoz Ag | Preparation of olefinic compounds |
EP0324347A2 (de) * | 1988-01-09 | 1989-07-19 | Hoechst Aktiengesellschaft | Neue 3,5-Dihydroxycarbonsäuren und deren Derivate, Verfahren zu ihrer Herstellung, ihre Verwendung als Arzneimittel, pharmazeutische Präparate und Zwischenprodukte |
EP0334014A2 (de) * | 1988-02-25 | 1989-09-27 | Bayer Ag | Substituierte Imidazolinone und Imidazolinthione |
Non-Patent Citations (1)
Title |
---|
CLAIMS SEARCHED: ALL * |
Also Published As
Publication number | Publication date |
---|---|
KR900006297A (ko) | 1990-05-07 |
LU87600A1 (fr) | 1990-05-15 |
JPH02188571A (ja) | 1990-07-24 |
BE1003007A3 (fr) | 1991-10-22 |
IT8948424A0 (it) | 1989-10-02 |
GB2223224B (en) | 1992-01-08 |
PT91878B (pt) | 1995-05-31 |
US5013749A (en) | 1991-05-07 |
NO893909D0 (no) | 1989-10-02 |
GB2223224A (en) | 1990-04-04 |
NL8902441A (nl) | 1990-05-01 |
AU628862B2 (en) | 1992-09-24 |
DE3932887A1 (de) | 1990-04-05 |
FR2637183A1 (fr) | 1990-04-06 |
PT91878A (pt) | 1990-04-30 |
SE8903226L (sv) | 1990-04-04 |
GB8922212D0 (en) | 1989-11-15 |
ES2019163A6 (es) | 1991-06-01 |
FI894648A0 (fi) | 1989-10-02 |
FI894648A (fi) | 1990-04-04 |
DK483689A (da) | 1990-04-04 |
SE8903226D0 (sv) | 1989-10-02 |
DK483689D0 (da) | 1989-10-02 |
NO893909L (no) | 1990-04-04 |
AU4243189A (en) | 1990-04-05 |
CH680442A5 (el) | 1992-08-31 |
IT1237470B (it) | 1993-06-07 |
US5120848A (en) | 1992-06-09 |
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