ES2002089A4 - Nuevas formulaciones farmaceuticas con liberacion programada que contienen antiflogisticos. - Google Patents
Nuevas formulaciones farmaceuticas con liberacion programada que contienen antiflogisticos.Info
- Publication number
- ES2002089A4 ES2002089A4 ES87110389T ES87110389T ES2002089A4 ES 2002089 A4 ES2002089 A4 ES 2002089A4 ES 87110389 T ES87110389 T ES 87110389T ES 87110389 T ES87110389 T ES 87110389T ES 2002089 A4 ES2002089 A4 ES 2002089A4
- Authority
- ES
- Spain
- Prior art keywords
- new
- pharmaceutical formulations
- scheduled release
- new pharmaceutical
- formulations
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 abstract 3
- 239000004480 active ingredient Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Abstract
NUEVAS FORMULACIONES GALENICAS CON LIBERACION PROGRAMADA, PARA SER ADMINISTRADAS POR VIA ORAL, QUE CONTIENEN COMO INGREDIENTE ACTIVO UN COMPUESTO DOTADO DE ACTIVIDAD ANTIFLOGISTICA, ANALGESICA Y ANTIPIRETICA, COMO POR EJEMPLO UN ACIDO ARILACETICO O ARILPROPIONICO Y SUS SALES FARMACEUTICAMENTE ACEPTABLES. EN ESTAS NUEVAS FORMULACIONES, UNA PARTE DEL INGREDIENTE ACTIVO SE LIBERA EN UN CORTO PERIODO DE TIEMPO, DE MODO QUE EL MEDICAMENTO PUEDE DESARROLLAR RAPIDAMENTE SU ACCION TERAPEUTICA ALCANZANDO LOS NIVELS HEMATICOS NECESARIOS, MIENTRAS QUE LA PARTE RESTANTE DEL COMPONENTE ACTIVO SE LIBERA EN UN INTERVALO DE TIEMPO MAS LARGO, DE MODO QUE PERMITE LA COBERTURA TERAPEUTICA HASTA LA SIGUIENTE ADMINISTRACION. DICHA COBERTURA TERAPEUTICA PUEDE INCLUSO DURAR 24 HORAS; ASI, LAS NUEVAS FORMULACIONES FARMACEUTICAS OBJETO DE LA PRESENTE INVENCION SON ADECUADAS PARA UNA ADMINISTRACION DIARIA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT03467/86A IT1200178B (it) | 1986-07-23 | 1986-07-23 | Formulazioni galeniche a cessione programmata contenenti farmaci ad attivita' antiflogistica |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2002089A4 true ES2002089A4 (es) | 1988-07-16 |
ES2002089T3 ES2002089T3 (es) | 1993-11-16 |
Family
ID=11107923
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES198787110389T Expired - Lifetime ES2002089T3 (es) | 1986-07-23 | 1987-07-17 | Nuevas formulaciones farmaceuticas con liberacion programada que contienen antiflogisticos. |
Country Status (13)
Country | Link |
---|---|
US (1) | US4888178A (es) |
EP (1) | EP0255002B1 (es) |
JP (1) | JPH0774155B2 (es) |
AT (1) | ATE75604T1 (es) |
DE (2) | DE3778781D1 (es) |
DK (1) | DK383987A (es) |
ES (1) | ES2002089T3 (es) |
FI (1) | FI92902C (es) |
GR (1) | GR3004509T3 (es) |
IE (1) | IE60220B1 (es) |
IT (1) | IT1200178B (es) |
NO (1) | NO174412C (es) |
ZA (1) | ZA874577B (es) |
Families Citing this family (74)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1215726B (it) * | 1988-01-18 | 1990-02-22 | Alfa Wassermann Spa | Formulazioni galeniche a cessione programmata. |
CH675537A5 (es) * | 1988-03-25 | 1990-10-15 | Ciba Geigy Ag | |
US5211957A (en) * | 1988-03-25 | 1993-05-18 | Ciba-Geigy Corporation | Solid rapidly disintegrating dosage form |
DE3822095A1 (de) * | 1988-06-30 | 1990-01-04 | Klinge Co Chem Pharm Fab | Neue arzneimittelformulierung sowie verfahren zu deren herstellung |
US5256699A (en) * | 1988-10-18 | 1993-10-26 | Ciba-Geify Corporation | Dispersible tablet formulation of diclofenac acid free base |
GB8824392D0 (en) | 1988-10-18 | 1988-11-23 | Ciba Geigy Ag | Dispersible formulation |
US4927639A (en) * | 1989-02-02 | 1990-05-22 | Warner-Lambert Company | Modified release gemfibrozil composition |
US4948581A (en) * | 1989-02-17 | 1990-08-14 | Dojin Iyaku-Kako Co., Ltd. | Long acting diclofenac sodium preparation |
DE69017915T2 (de) * | 1989-10-26 | 1995-07-27 | Nippon Shinyaku Co Ltd | Zubereitung für den magen. |
US5169645A (en) * | 1989-10-31 | 1992-12-08 | Duquesne University Of The Holy Ghost | Directly compressible granules having improved flow properties |
KR910011145A (ko) * | 1989-12-14 | 1991-08-07 | 다니엘 에이. 스콜라 2세 | 향미를 오랫동안 지속적으로 방출하는 여러개의 캡슐로 싸여진 시스템을 갖는 압축된 당과류 정제 |
EP0437098A3 (en) * | 1990-01-11 | 1991-09-18 | Warner-Lambert Company | Compressed confectionery tablets with at least two phases and sequential flavour delivery system |
IE66933B1 (en) * | 1990-01-15 | 1996-02-07 | Elan Corp Plc | Controlled absorption naproxen formulation for once-daily administration |
US5198227A (en) * | 1990-01-22 | 1993-03-30 | Mcneil-Ppc, Inc. | Dual subcoated simulated capsule medicament |
JP2572673B2 (ja) * | 1990-07-25 | 1997-01-16 | エスエス製薬株式会社 | 徐放性錠剤 |
GB9022788D0 (en) * | 1990-10-19 | 1990-12-05 | Cortecs Ltd | Pharmaceutical formulations |
JP2829794B2 (ja) * | 1991-02-08 | 1998-12-02 | エスエス製薬 株式会社 | 徐放性経口投与型プラノプロフェン製剤 |
US5464632C1 (en) * | 1991-07-22 | 2001-02-20 | Prographarm Lab | Rapidly disintegratable multiparticular tablet |
FR2679451B1 (fr) * | 1991-07-22 | 1994-09-09 | Prographarm Laboratoires | Comprime multiparticulaire a delitement rapide. |
DE4140184C2 (de) * | 1991-12-05 | 1995-12-21 | Alfatec Pharma Gmbh | Akutform für ein Flurbiprofen enthaltendes Arzneimittel |
DE4140183C2 (de) * | 1991-12-05 | 1995-12-21 | Alfatec Pharma Gmbh | Retardform für ein Flurbiprofen enthaltendes Arzneimittel |
DE4140185C2 (de) * | 1991-12-05 | 1996-02-01 | Alfatec Pharma Gmbh | Ein 2-Arylpropionsäurederivat in Nanosolform enthaltendes Arzneimittel und seine Herstellung |
DE4140172C2 (de) * | 1991-12-05 | 1995-12-21 | Alfatec Pharma Gmbh | Retardform für ein Ibuprofen enthaltendes Arzneimittel |
WO1993017673A1 (en) * | 1992-03-03 | 1993-09-16 | Top Gold Pty., Limited | Sustained release analgesics |
US5609884A (en) * | 1992-08-31 | 1997-03-11 | G. D. Searle & Co. | Controlled release naproxen sodium plus naproxen combination tablet |
IT1258143B (it) * | 1992-09-11 | 1996-02-20 | Alfa Wassermann Spa | Compresse a cessione programmata contenenti naproxen |
CA2128820A1 (en) * | 1993-07-27 | 1995-01-28 | Walter G. Gowan, Jr. | Rapidly disintegrating pharmaceutical dosage form and process for preparation thereof |
US6676967B1 (en) | 1993-09-20 | 2004-01-13 | Kos Pharmaceuticals, Inc. | Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia |
US6129930A (en) | 1993-09-20 | 2000-10-10 | Bova; David J. | Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night |
US6818229B1 (en) | 1993-09-20 | 2004-11-16 | Kos Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia |
US6080428A (en) | 1993-09-20 | 2000-06-27 | Bova; David J. | Nicotinic acid compositions for treating hyperlipidemia and related methods therefor |
US6746691B2 (en) | 1993-09-20 | 2004-06-08 | Kos Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics |
US6210714B1 (en) * | 1993-11-23 | 2001-04-03 | Euro-Celtique S.A. | Immediate release tablet cores of acetaminophen having sustained-release coating |
GB9325445D0 (en) * | 1993-12-13 | 1994-02-16 | Cortecs Ltd | Pharmaceutical formulations |
US5830884A (en) * | 1995-01-18 | 1998-11-03 | National Starch And Chemical Investment Holding Corporation | Pharmaceutical products containing thermally-inhibited starches |
AU5200098A (en) | 1996-11-01 | 1998-05-29 | Ilex Oncology, Inc. | Sustained release formulation containing dfmo |
US6312724B1 (en) | 1997-04-04 | 2001-11-06 | Isa Odidi | Sustained release pharmaceutical matrix tablet of pharmaceutically acceptable salts of diclofenac and process for preparation thereof |
FR2766089B1 (fr) * | 1997-07-21 | 2000-06-02 | Prographarm Lab | Comprime multiparticulaire perfectionne a delitement rapide |
AR016827A1 (es) | 1997-08-22 | 2001-08-01 | Smithkline Beecham Corp | PROCEDIMIENTO PARA LA PREPARACIoN DE UNA TABLETA FARMACÉUTICA |
AR017512A1 (es) | 1997-08-22 | 2001-09-12 | Smithkline Beecham Corp | Tabletas de metilcelulosa rapidamente desintegrables para administracion por via oral y procedimiento para prepararlas |
EP0898961A1 (de) * | 1997-08-27 | 1999-03-03 | Herta-Maria Dr. Sahlender | Pharmazeutische Zubereitung zur verbesserten Schmerztherapie bei akutem, postoperativem oder chronischem Schmerz |
US20030153623A1 (en) * | 1998-07-22 | 2003-08-14 | Yamanouchi Pharmaceutical Co., Ltd. | Solid preparation containing sparingly soluble NSAIDs |
US6153225A (en) * | 1998-08-13 | 2000-11-28 | Elan Pharma International Limited | Injectable formulations of nanoparticulate naproxen |
SE9802973D0 (sv) | 1998-09-03 | 1998-09-03 | Astra Ab | Immediate release tablet |
US6165506A (en) * | 1998-09-04 | 2000-12-26 | Elan Pharma International Ltd. | Solid dose form of nanoparticulate naproxen |
US20090297597A1 (en) * | 1998-11-02 | 2009-12-03 | Gary Liversidge | Modified Release Ticlopidine Compositions |
US20070122481A1 (en) * | 1998-11-02 | 2007-05-31 | Elan Corporation Plc | Modified Release Compositions Comprising a Fluorocytidine Derivative for the Treatment of Cancer |
US20060240105A1 (en) * | 1998-11-02 | 2006-10-26 | Elan Corporation, Plc | Multiparticulate modified release composition |
US20090149479A1 (en) * | 1998-11-02 | 2009-06-11 | Elan Pharma International Limited | Dosing regimen |
AU2012202743B2 (en) * | 1998-11-02 | 2014-02-27 | Alkermes Pharma Ireland Limited | Multiparticulate modified release composition |
PT1126826E (pt) * | 1998-11-02 | 2008-11-25 | Elan Pharma Int Ltd | Composição de metilfenidato de libertação modificada multiparticulada |
US10179130B2 (en) | 1999-10-29 | 2019-01-15 | Purdue Pharma L.P. | Controlled release hydrocodone formulations |
KR101476574B1 (ko) | 1999-10-29 | 2014-12-24 | 유로-셀티크 소시에떼 아노뉨 | 서방성 하이드로코돈 제형 |
US6340471B1 (en) * | 1999-12-30 | 2002-01-22 | Alvin Kershman | Method for preparing solid delivery system for encapsulated and non-encapsulated pharmaceuticals |
US6607748B1 (en) | 2000-06-29 | 2003-08-19 | Vincent Lenaerts | Cross-linked high amylose starch for use in controlled-release pharmaceutical formulations and processes for its manufacture |
MXPA03003895A (es) | 2000-10-30 | 2003-07-28 | Euro Celtique Sa | Formulaciones de hidrocodona de liberacion controlada. |
DE10300325A1 (de) | 2003-01-09 | 2004-07-22 | Hexal Ag | Granulat mit öliger Substanz, Herstellungsverfahren und Tablette |
US7344907B2 (en) * | 2004-11-19 | 2008-03-18 | International Business Machines Corporation | Apparatus and methods for encapsulating microelectromechanical (MEM) devices on a wafer scale |
WO2006063078A2 (en) * | 2004-12-08 | 2006-06-15 | Elan Corporation, Plc | Topiramate pharmaceuticals composition |
US20070298098A1 (en) * | 2005-02-16 | 2007-12-27 | Elan Pharma International Limited | Controlled Release Compositions Comprising Levetiracetam |
KR20080007586A (ko) * | 2005-04-12 | 2008-01-22 | 엘란 파마 인터내셔널 리미티드 | 세균감염증의 치료를 위한 세팔로스포린 함유 조절 방출조성물 |
JP4936420B2 (ja) * | 2005-08-02 | 2012-05-23 | 塩野義製薬株式会社 | 徐放性顆粒剤 |
RU2462242C2 (ru) * | 2007-08-15 | 2012-09-27 | МакНЕЙЛ-ППС, ИНК. | Режим дозирования ибупрофена с немедленным высвобождением и замедленным высвобождением |
EP2190418B1 (en) | 2007-08-15 | 2013-10-02 | Mcneil-PPC, Inc | Immediate release and sustained release ibuprofen dosing regimen |
US20090311335A1 (en) * | 2008-06-12 | 2009-12-17 | Scott Jenkins | Combination of a triptan and an nsaid |
EP2480212B1 (en) * | 2009-09-25 | 2016-07-06 | Novartis Consumer Health S.A. | Oral pharmaceutical composition comprising diclofenac |
EP3288556A4 (en) | 2015-04-29 | 2018-09-19 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
MX2018004356A (es) * | 2015-10-09 | 2018-05-23 | Bayer Healthcare Llc | Formulacion de liberacion modificada de naproxeno sodico. |
US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
JP7163015B2 (ja) * | 2016-10-31 | 2022-10-31 | エスエス製薬株式会社 | 経口固形組成物 |
BR112020011189A2 (pt) | 2017-12-05 | 2020-11-17 | Sunovion Pharmaceuticals Inc. | misturas não racêmicas e usos das mesmas |
MX2020005517A (es) | 2017-12-05 | 2020-11-09 | Sunovion Pharmaceuticals Inc | Formas cristalinas y metodos de produccion de las mismas. |
CN110037994B (zh) * | 2019-05-24 | 2022-04-12 | 中国药科大学 | 一种布洛芬速释缓释双层片及其制备方法 |
US11160758B2 (en) | 2019-06-04 | 2021-11-02 | Sunovion Pharmaceuticals Inc. | Modified release formulations and uses thereof |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2793979A (en) * | 1953-03-30 | 1957-05-28 | Smith Kline French Lab | Method of making a sustained release pharmaceutical tablet and product of the method |
FR1159165A (fr) * | 1953-11-03 | 1958-06-24 | Smith Kline French Lab | Comprimé pharmaceutique ou pilule et son procédé de fabrication |
US3044938A (en) * | 1955-07-01 | 1962-07-17 | Sandoz Chemical Works Inc | Sustained action pharmaceutical tablets |
US3388041A (en) * | 1964-01-27 | 1968-06-11 | Richardson Merrell Inc | High dosage sustained release tablet |
US4012498A (en) * | 1974-03-27 | 1977-03-15 | Sandoz, Inc. | Sustained release tablet formulations |
US4167588A (en) * | 1974-04-10 | 1979-09-11 | Willard Miles J | Preparation of fabricated baked potato product |
JPS5661311A (en) * | 1979-10-25 | 1981-05-26 | Fujisawa Pharmaceut Co Ltd | Thial amide or prolonged pharmaceutical preparation comprising its salt |
DK151608C (da) * | 1982-08-13 | 1988-06-20 | Benzon As Alfred | Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat med kontrolleret afgivelse |
JPS604120A (ja) * | 1983-06-22 | 1985-01-10 | Shionogi & Co Ltd | 作用持続型ピナシジル製剤 |
-
1986
- 1986-07-23 IT IT03467/86A patent/IT1200178B/it active
-
1987
- 1987-06-24 ZA ZA874577A patent/ZA874577B/xx unknown
- 1987-07-17 AT AT87110389T patent/ATE75604T1/de not_active IP Right Cessation
- 1987-07-17 ES ES198787110389T patent/ES2002089T3/es not_active Expired - Lifetime
- 1987-07-17 DE DE8787110389T patent/DE3778781D1/de not_active Expired - Fee Related
- 1987-07-17 EP EP87110389A patent/EP0255002B1/en not_active Expired - Lifetime
- 1987-07-17 DE DE198787110389T patent/DE255002T1/de active Pending
- 1987-07-22 FI FI873225A patent/FI92902C/fi not_active IP Right Cessation
- 1987-07-22 JP JP62183235A patent/JPH0774155B2/ja not_active Expired - Lifetime
- 1987-07-22 IE IE198187A patent/IE60220B1/en not_active IP Right Cessation
- 1987-07-22 NO NO873072A patent/NO174412C/no unknown
- 1987-07-22 DK DK383987A patent/DK383987A/da not_active Application Discontinuation
-
1989
- 1989-04-12 US US07/336,507 patent/US4888178A/en not_active Expired - Fee Related
-
1992
- 1992-05-07 GR GR920400501T patent/GR3004509T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
FI873225A (fi) | 1988-01-24 |
EP0255002B1 (en) | 1992-05-06 |
NO174412C (no) | 1994-05-04 |
US4888178A (en) | 1989-12-19 |
JPH0774155B2 (ja) | 1995-08-09 |
IT8603467A0 (it) | 1986-07-23 |
GR3004509T3 (es) | 1993-04-28 |
IE871981L (en) | 1988-01-23 |
NO174412B (no) | 1994-01-24 |
DK383987D0 (da) | 1987-07-22 |
FI873225A0 (fi) | 1987-07-22 |
NO873072L (no) | 1988-01-25 |
ZA874577B (en) | 1988-01-19 |
FI92902C (fi) | 1995-01-25 |
JPS6354316A (ja) | 1988-03-08 |
IE60220B1 (en) | 1994-06-15 |
ATE75604T1 (de) | 1992-05-15 |
EP0255002A1 (en) | 1988-02-03 |
NO873072D0 (no) | 1987-07-22 |
ES2002089T3 (es) | 1993-11-16 |
IT1200178B (it) | 1989-01-05 |
DE3778781D1 (de) | 1992-06-11 |
FI92902B (fi) | 1994-10-14 |
DE255002T1 (de) | 1988-08-11 |
DK383987A (da) | 1988-01-24 |
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