EP4147990B1 - Dispositif de distribution de liquide comprenant une surface d'appui pour un ressort - Google Patents

Dispositif de distribution de liquide comprenant une surface d'appui pour un ressort Download PDF

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Publication number
EP4147990B1
EP4147990B1 EP22201129.8A EP22201129A EP4147990B1 EP 4147990 B1 EP4147990 B1 EP 4147990B1 EP 22201129 A EP22201129 A EP 22201129A EP 4147990 B1 EP4147990 B1 EP 4147990B1
Authority
EP
European Patent Office
Prior art keywords
valve
wall
tubular wall
support
fastener
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP22201129.8A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP4147990A1 (fr
Inventor
Gaëtan Painchaud
Guillaume Grevin
Xavier Julia
Thierry Decock
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nemera la Verpilliere SAS
Original Assignee
Nemera la Verpilliere SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Application filed by Nemera la Verpilliere SAS filed Critical Nemera la Verpilliere SAS
Priority to EP25184660.6A priority Critical patent/EP4596110A3/fr
Publication of EP4147990A1 publication Critical patent/EP4147990A1/fr
Application granted granted Critical
Publication of EP4147990B1 publication Critical patent/EP4147990B1/fr
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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D47/00—Closures with filling and discharging, or with discharging, devices
    • B65D47/04—Closures with discharging devices other than pumps
    • B65D47/20—Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge
    • B65D47/2018—Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge comprising a valve or like element which is opened or closed by deformation of the container or closure
    • B65D47/2031—Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge comprising a valve or like element which is opened or closed by deformation of the container or closure the element being formed by a slit, narrow opening or constrictable spout, the size of the outlet passage being able to be varied by increasing or decreasing the pressure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005—Components or details
    • B05B11/0037—Containers
    • B05B11/0039—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means
    • B05B11/0044—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means compensating underpressure by ingress of atmospheric air into the container, i.e. with venting means
    • B05B11/00444—Containers associated with means for compensating the pressure difference between the ambient pressure and the pressure inside the container, e.g. pressure relief means compensating underpressure by ingress of atmospheric air into the container, i.e. with venting means with provision for filtering or cleaning the air flow drawn into the container
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D47/00—Closures with filling and discharging, or with discharging, devices
    • B65D47/04—Closures with discharging devices other than pumps
    • B65D47/20—Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge
    • B65D47/2018—Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge comprising a valve or like element which is opened or closed by deformation of the container or closure
    • B65D47/2056—Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge comprising a valve or like element which is opened or closed by deformation of the container or closure lift valve type
    • B65D47/2081—Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge comprising a valve or like element which is opened or closed by deformation of the container or closure lift valve type in which the deformation raises or lowers the valve port
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49826—Assembling or joining

Definitions

  • the invention relates to the field of dispensing liquid in the form of drops, in particular in the pharmaceutical field, for example ophthalmic or ear liquid.
  • a liquid dispensing device comprising an elastomeric diaphragm forming a valve, disposed between a support and a cover mounted on the reservoir.
  • the diaphragm comprises an annular peripheral bead and is held on the device by pinching this bead between the upper surface of the support and the lower surface of the cover. The diaphragm is therefore held in the device by pinching in the axial direction of the device.
  • a disadvantage of this type of assembly is that when a user presses the reservoir to release liquid, the liquid exerts pressure on the diaphragm in the axial direction to open it, and such pressure can cause liquid to leak around the periphery of the diaphragm. This risk of leakage is all the more likely if the parts have dimensions or relative positions that can vary, due to manufacturing tolerances.
  • the presence of a leak in the device is inconvenient, and even more so if the liquid does not contain a preservative, because liquid ends up in undesirable places in the device, which encourages the growth of bacteria and can subsequently contaminate the liquid.
  • the present invention aims in particular to provide a dispensing device in which sterility is improved.
  • the inner and outer tubular walls are arranged in such a way that they effect radial compression of the fixing wall of the valve, that is to say that they press on either side of the fixing wall, in the radial direction, corresponding to the direction perpendicular to the axis of the tubular walls, this radial compression ensuring sealing of the valve.
  • the distribution device comprises, in the valve attachment area, three concentric tubes, possibly of short length, the inner tube corresponding to the inner tubular wall, the intermediate tube corresponding to the valve attachment wall and the outer tube corresponding to the tubular wall external.
  • These tubes all have the same axis, corresponding to the axis of the distribution device, this axis generally being an axis of revolution of the device, in particular of the reservoir, corresponding to the direction in which the liquid comes out of the valve. It is understood that, to ensure satisfactory sealing, the diameter of the internal tubular wall is slightly greater than the diameter of the fixing wall, itself slightly greater than the diameter of the external tubular wall.
  • the seal is obtained by clamping in a direction other than the liquid ejection direction.
  • the pressure exerted by the liquid, in the axial direction is not exerted in the direction ensuring the sealing of the valve fixation.
  • the liquid exerts axial pressure on the valve, generating a relatively low stress in the radial direction of the valve.
  • the risk of displacement of the valve fixation elements, such as the inner and outer tubular walls, is relatively low.
  • valve fixation is ensured by clamping in the axial direction, which generally corresponds to the assembly direction of the fixation elements, and which tends to displace these fixation elements and therefore to generate leaks. It is understood that the proposed configuration generates less stress on the fixing elements, therefore a better seal, therefore a more sterile device ensuring good operation.
  • the proposed device requires less precision in the dimensions of the fasteners.
  • the clamping by means of the tubes guarantees a good seal, even if the components have relative positions that may vary slightly in the axial direction due to manufacturing tolerances or positioning tolerances during assembly in the axial direction.
  • the outer or inner tubular wall can advantageously constitute a centering wall of the valve, which facilitates its assembly.
  • tubular walls is advantageous in terms of compactness. Indeed, the axial position of the fixing zone can be moved further downstream of the distribution device, for example on either side of the valve-forming part, which can make it possible to reduce the diameter of the distribution nozzle. Furthermore, because the seal is provided by tubular walls, the compression surface area exerted by the fixing elements is increased, which provides better sealing.
  • the proposed device is very useful in cases where one wishes to distribute a liquid that does not contain a preservative. Indeed, with this type of liquid, compliance with the seal must be particularly reliable.
  • provision may be made for the insertion of a spring between the step of installing the valve on the support and the step of installing the cover over the valve, the spring being inserted around a central cylindrical portion of the valve.
  • the dispensed liquid is, in this example, a pharmaceutical liquid, such as ophthalmic or ear liquid.
  • the device 10 comprises a dispensing tip 12, mounted by screwing onto the neck of a reservoir 13.
  • the device 10 is configured so as to dispense liquid following pressure exerted by the user on the reservoir 13.
  • the reservoir is elastically deformable, so as to return to its shape after pressure exerted by the user.
  • the device 10, at least the reservoir 13, has an axis X of revolution, also corresponding to the direction of liquid ejection.
  • the nozzle 12 comprises a support 14, a valve 16, a spring 17, a cover 18 and a hydrophobic filter 20.
  • the support 14 comprises, in this example, a part 22, arranged at the proximal end of the tip, for fixing the support to the reservoir 13.
  • This part 22 comprises an external skirt 24, threaded so as to be screwed onto the neck of the reservoir 13, and an internal skirt 26, of tubular shape, making it possible to ensure sealing between the reservoir 12 and the dispensing tip 10.
  • the support 14 further comprises an intermediate part 28, forming a seat for the valve 16.
  • This intermediate part 28 has substantially the shape of a disc, extending in a radial plane R perpendicular to the axis X.
  • the disc 28 is delimited, on its distal face, by an external tubular wall 30. This wall forms a peripheral skirt of the disc 28, it extends perpendicular to the disc 28, in the form of a tube of axis X, sufficiently high to receive the valve 16, as described below.
  • the disc 28 comprises, in the lower vicinity of the tubular wall 30, an annular rib 32, making it possible to delimit a centering and receiving groove for the edge of the valve 16.
  • the disc 28 further comprises a cylindrical central part 34 for closing the valve, projecting from its center, on the distal side of the disc 28 and carrying, at its distal end, a surface 36 for bearing the valve 16.
  • This part 34 forms a closing pin allowing the opening or closing of the valve 16.
  • the disc 28 is furthermore crossed by a channel 38 for the passage of liquid coming from the reservoir.
  • This channel 38 opens onto a cavity 40, delimited in particular by a recess made on the distal surface of the disc 28.
  • This cavity 40 also opens onto a second channel 42 for the passage of liquid, delimited by the pin 34 and the valve 16.
  • the channels 38 and 42 have an axis substantially parallel to the axis X.
  • the disc 28, the outer tubular wall 30 and the closing pin 34 define a tubular cavity for receiving the valve 16.
  • the support 14 comprises a channel 44 for the passage of air into the reservoir, this channel 44 opening onto a housing 46 for receiving the hydrophobic filter 20, this housing 46 being cylindrical, open at its proximal end for the insertion of the filter 20.
  • the valve 16 comprises a central cylindrical part 48, an annular peripheral skirt 50, the central part 48 and the skirt 50 being connected to each other by a web of material 52.
  • the web 52 carries, on its distal surface, a seat 53 for supporting the spring 17.
  • the distal part 54 of the central part 48 is a valve-forming part, ensuring the blocking and passage of liquid, by cooperation with the bearing surface 36.
  • the surface 36 forms a support for the valve-forming part 54 when the latter is in the liquid blocking configuration.
  • the upper surface of the part 48 comprises a channel 56 for ejecting the liquid, opening onto a drop metering form 58.
  • the skirt 50 forms a fixing edge of the valve 16 on the support, for the permanent fixing of the valve relative to the tank 13. It is made up of a fixing wall 50, tubular with axis X, with a diameter slightly greater than the internal diameter of the external tubular wall 30.
  • the valve 16 is entirely made of an elastomer material.
  • the valve comprises certain parts made of an elastomer material and other parts made of a more rigid material, in particular the part 53 forming a support for the spring 17.
  • the part forming a valve 54, the web 52 and the fixing wall 50 are made of an elastomer material.
  • the cover 18 is attached by snap-fastening to the support 16, using snap-fastening means 59.
  • the snap-fastening means 59 make it possible to snap-fasten the cover 18 relative to the support 14 following assembly in the axial direction X.
  • It carries an internal tubular wall 60, with axis X and a diameter slightly greater than the diameter of the fixing wall 50 of the valve.
  • the cover 18 further comprises an outer casing 62 forming an outer skirt, extending towards the proximal direction relative to the rest of the cover 18, as well as a bottom 64, so that the wall 60, the bottom 64 and the casing 62 delimit a groove intended to sandwich the fixing wall 50 and the outer tubular wall 30.
  • the cover 18 largely covers the valve 16, while however being crossed in its center by the central part 48 of the valve.
  • the cover 18 delimits a cylindrical cavity by means of a tubular inner skirt 66, having a function of centering the valve 16.
  • the skirt 66 also delimits a groove 68 forming a support seat for the spring 17.
  • the pressure of the fluid in the channel 42 deforms the valve-forming part 54, so as to make it pass from its liquid-blocking configuration to a liquid-passing configuration, by detachment of the part 54 from the bearing surface 36. This deformation is facilitated by the compression of the spring 17 under the pressure of the liquid. The liquid is then distributed in the form of drops.
  • the assembly comprises a step of assembling the end piece 12, followed by a step of screwing this end piece 12 onto the tank 13.
  • the assembly of the tip 12 begins with a step of installing the valve 16 on the support 14, by inserting the fixing wall 50 of the valve inside the tubular wall 30 of the support 14. This step is illustrated in the Figure 2a , it is followed by a step of inserting the spring 17 around the central part 48 of the valve, illustrated in the Figure 2b . Once the spring is in place, we move on to a step of installing the cover 18 above the valve 16, illustrated in the Figure 2c , by inserting the inner tubular wall 60 inside the fixing wall 50. This installation of the cover 18 is completed by snapping the cover onto the support 14, illustrated in the figure 2d , this snap-fastening being simultaneous with the permanent fixing of the valve 16 on the end piece 12, sandwiched between the inner 60 and outer 30 tubular walls. It will be noted that when the valve 16 is fixed on the device, the web 52 is put under elastic stress so as to press the end 54 against the surface 36. This pressing is further facilitated by the return force of the spring.
  • the static sealing achieved around the fixing wall 50, by pinching the walls 60 and 30, is particularly effective. Indeed, when the liquid escapes from the reservoir 13, it exerts pressure on the valve 16 in the X direction, and this pressure in the X direction is not reflected on the fixing part 50, the fixing of the valve being ensured by compression in the radial direction R.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Closures For Containers (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Springs (AREA)
  • Check Valves (AREA)
  • Feeding And Controlling Fuel (AREA)
  • Devices For Dispensing Beverages (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
EP22201129.8A 2009-09-11 2010-09-09 Dispositif de distribution de liquide comprenant une surface d'appui pour un ressort Active EP4147990B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP25184660.6A EP4596110A3 (fr) 2009-09-11 2010-09-09 Dispositif de distribution de liquide comprenant une surface d'appui pour un ressort

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR0956278A FR2950036B1 (fr) 2009-09-11 2009-09-11 Dispositif de distribution de liquide
EP16175337.1A EP3090957B1 (fr) 2009-09-11 2010-09-09 Dispositif de distribution de liquide comprenant une surface d'appui pour un ressort
PCT/FR2010/051877 WO2011030062A1 (fr) 2009-09-11 2010-09-09 Dispositif de distribution de liquide
EP10768998.6A EP2475585B1 (fr) 2009-09-11 2010-09-09 Dispositif de distribution de liquide

Related Parent Applications (3)

Application Number Title Priority Date Filing Date
EP16175337.1A Division EP3090957B1 (fr) 2009-09-11 2010-09-09 Dispositif de distribution de liquide comprenant une surface d'appui pour un ressort
EP16175337.1A Division-Into EP3090957B1 (fr) 2009-09-11 2010-09-09 Dispositif de distribution de liquide comprenant une surface d'appui pour un ressort
EP10768998.6A Division EP2475585B1 (fr) 2009-09-11 2010-09-09 Dispositif de distribution de liquide

Related Child Applications (1)

Application Number Title Priority Date Filing Date
EP25184660.6A Division EP4596110A3 (fr) 2009-09-11 2010-09-09 Dispositif de distribution de liquide comprenant une surface d'appui pour un ressort

Publications (2)

Publication Number Publication Date
EP4147990A1 EP4147990A1 (fr) 2023-03-15
EP4147990B1 true EP4147990B1 (fr) 2025-06-25

Family

ID=42097280

Family Applications (5)

Application Number Title Priority Date Filing Date
EP22201129.8A Active EP4147990B1 (fr) 2009-09-11 2010-09-09 Dispositif de distribution de liquide comprenant une surface d'appui pour un ressort
EP16175332.2A Withdrawn EP3090956A1 (fr) 2009-09-11 2010-09-09 Dispositif de distribution de liquide comprenant une valve formant clapet
EP10768998.6A Active EP2475585B1 (fr) 2009-09-11 2010-09-09 Dispositif de distribution de liquide
EP25184660.6A Pending EP4596110A3 (fr) 2009-09-11 2010-09-09 Dispositif de distribution de liquide comprenant une surface d'appui pour un ressort
EP16175337.1A Active EP3090957B1 (fr) 2009-09-11 2010-09-09 Dispositif de distribution de liquide comprenant une surface d'appui pour un ressort

Family Applications After (4)

Application Number Title Priority Date Filing Date
EP16175332.2A Withdrawn EP3090956A1 (fr) 2009-09-11 2010-09-09 Dispositif de distribution de liquide comprenant une valve formant clapet
EP10768998.6A Active EP2475585B1 (fr) 2009-09-11 2010-09-09 Dispositif de distribution de liquide
EP25184660.6A Pending EP4596110A3 (fr) 2009-09-11 2010-09-09 Dispositif de distribution de liquide comprenant une surface d'appui pour un ressort
EP16175337.1A Active EP3090957B1 (fr) 2009-09-11 2010-09-09 Dispositif de distribution de liquide comprenant une surface d'appui pour un ressort

Country Status (10)

Country Link
US (1) US8863998B2 (cs)
EP (5) EP4147990B1 (cs)
JP (1) JP5739890B2 (cs)
CN (1) CN102712395B (cs)
BR (1) BR112012005428B1 (cs)
ES (2) ES3041783T3 (cs)
FR (1) FR2950036B1 (cs)
IN (1) IN2012DN02150A (cs)
PL (2) PL3090957T3 (cs)
WO (1) WO2011030062A1 (cs)

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EP3773794A1 (en) 2018-04-13 2021-02-17 Novo Nordisk A/S Flow communication unit with unconnected and connected configuration
FR3080844B1 (fr) * 2018-05-07 2020-06-05 Horus Pharma Dispositif de conditionnement et distribution d'un produit avec flacon et embout doseur muni d'un filtre
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US12097145B2 (en) 2019-03-06 2024-09-24 Bausch + Lomb Ireland Limited Vented multi-dose ocular fluid delivery system
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US12290472B2 (en) 2020-04-17 2025-05-06 Bausch + Lomb Ireland Limited Hydrodynamically actuated preservative free dispensing system
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Publication number Publication date
PL3090957T3 (pl) 2024-01-03
EP3090957A1 (fr) 2016-11-09
FR2950036B1 (fr) 2011-12-16
IN2012DN02150A (cs) 2015-08-07
EP3090956A1 (fr) 2016-11-09
EP4596110A3 (fr) 2025-10-15
US20120223106A1 (en) 2012-09-06
ES3041783T3 (en) 2025-11-14
CN102712395B (zh) 2015-02-11
EP3090957B1 (fr) 2023-08-09
BR112012005428A2 (pt) 2016-04-12
BR112012005428B1 (pt) 2019-07-09
EP2475585A1 (fr) 2012-07-18
EP4596110A2 (fr) 2025-08-06
FR2950036A1 (fr) 2011-03-18
US8863998B2 (en) 2014-10-21
PL4147990T3 (pl) 2025-10-13
EP4147990A1 (fr) 2023-03-15
ES2961272T3 (es) 2024-03-11
WO2011030062A1 (fr) 2011-03-17
JP2013504496A (ja) 2013-02-07
CN102712395A (zh) 2012-10-03
EP2475585B1 (fr) 2018-01-17
JP5739890B2 (ja) 2015-06-24

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