EP3795254B1 - Austauschbare kolben-zylinder-einheit für einen dispenser - Google Patents

Austauschbare kolben-zylinder-einheit für einen dispenser Download PDF

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Publication number
EP3795254B1
EP3795254B1 EP20207075.1A EP20207075A EP3795254B1 EP 3795254 B1 EP3795254 B1 EP 3795254B1 EP 20207075 A EP20207075 A EP 20207075A EP 3795254 B1 EP3795254 B1 EP 3795254B1
Authority
EP
European Patent Office
Prior art keywords
piston
cylinder unit
dispenser
recess
information carrier
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP20207075.1A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP3795254A1 (de
Inventor
Daniel Setzer
Jürgen Schraut
Renate Rempt
Rainer Feldmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brand GmbH and Co KG
Original Assignee
Brand GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Publication of EP3795254A1 publication Critical patent/EP3795254A1/de
Application granted granted Critical
Publication of EP3795254B1 publication Critical patent/EP3795254B1/de
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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0234—Repeating pipettes, i.e. for dispensing multiple doses from a single charge
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0275—Interchangeable or disposable dispensing tips
    • B01L3/0279—Interchangeable or disposable dispensing tips co-operating with positive ejection means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/143—Quality control, feedback systems
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/021—Identification, e.g. bar codes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons

Definitions

  • the invention relates to an exchangeable piston-cylinder unit for a dispenser according to claim 1.
  • the invention also relates to a dispenser according to claim 6, a system for receiving and dispensing fluid volumes according to claim 15 and a method for identifying the type of an exchangeable piston-cylinder Unit for a dispenser according to claim 16.
  • the task of systems of the type in question is to take up a volume of fluid from one container and then to dispense it into another or several other containers.
  • Such systems are used in particular for the repeated dispensing, titration or pipetting of liquids.
  • Such systems include a dispenser and a piston-cylinder unit designed as an interchangeable part, which can be detachably attached to the dispenser, in particular inserted or inserted. After one or more dispensing processes, the piston-cylinder unit can be detached from the dispenser. Another, in particular different, piston-cylinder unit can then be attached to the dispenser.
  • Such systems can be designed as manual or motor-operated hand-held devices, to the dispenser of which precisely one piston-cylinder unit can be attached.
  • Piston-cylinder units of the type in question can, for. B. be designed as displacement units with attachable pipettes or tips (tips) or as syringes. They each have a cylinder, in particular with a straight hollow cylinder with a substantially circular cross-section and an axial direction perpendicular thereto, and a piston which can be displaced in the cylinder in its axial direction. By moving the piston fluids can be in the Cylinder or in the tip attached therein and dispensed from it.
  • the piston-cylinder units can be attached to the dispenser by means of a movement running at least substantially in the axial direction of the dispenser. This allows a simple, user-friendly, ergonomically advantageous and less error-prone operation of the corresponding system.
  • axial direction of the dispenser denotes an alignment that corresponds to or parallel to the longitudinal axis of the dispenser.
  • the focus of the present invention is on piston-cylinder units that work according to the positive displacement principle and are suitable for dispensing liquids with high viscosity and / or high vapor pressure.
  • type refers to e.g. B. a purpose, a condition and / or a property of the piston-cylinder unit, such as. B. the maximum fluid volume that can be absorbed and / or delivered.
  • a pipette system which has a syringe having a fastening section and a syringe plunger and a pipette.
  • the pipette has a receptacle for the fastening section in a pipette housing and a plunger receptacle for the syringe plunger in a receptacle body.
  • the pipette also has fastening devices for reversibly fixing the fastening section and the syringe plunger in their receptacles and plunger adjusting devices for moving the receptacle body in the pipette housing.
  • the syringe has an information carrier with information about the syringe and / or its condition.
  • the pipette has a scanning device for the information on the information carrier.
  • the fastening section and the syringe plunger can be pushed axially into their fastening positions in the pipette through axial openings in their receptacles.
  • the information carrier arrives at a scanning position with respect to the scanning device.
  • the syringe flange has a ring with at least one axially directed scanning surface at an axial position as an information carrier.
  • the piston-cylinder unit has several information carrier sections. All of the information carried by all of the information carrier sections specifies the type of piston-cylinder unit. All information carrier sections are aligned radially, ie the information (s) of an information carrier section is / are encoded in its radial direction. All information carrier sections are arranged on a flange of the cylinder of the respective piston-cylinder unit.
  • the dispenser has a detection device for automatically identifying the type of piston-cylinder unit attached to the dispenser.
  • the detection device has a radial information reader by means of which the information of the radially aligned information carrier sections can be detected.
  • One object of the present invention is to improve the known method or the associated system or the known dispenser or the known piston-cylinder unit with regard to reliability, precision, sequence, structure, handling, stability and / or durability.
  • a basic idea of the present invention is to combine at least two different options for coding information.
  • the combination of a radial coding of information with an axial coding of information has proven to be particularly advantageous here.
  • the piston-cylinder unit has at least one radially oriented information carrier section which at least partially specifies the type of piston-cylinder unit and at least one, preferably exactly one, axially specifying the type of piston-cylinder unit at least partially aligned information carrier section.
  • radially oriented information carrier section is to be understood to mean that this information carrier section is accessible in the radial direction of the piston-cylinder unit and / or its information can be detected in the radial direction of the piston-cylinder unit.
  • the radially oriented information carrier section has a geometric extension in the radial direction of the piston-cylinder unit, by means of which the detectable information of the radial information carrier section is coded.
  • the radially oriented information carrier section has a geometric extension in the axial direction of the piston-cylinder unit and in the circumferential direction of the piston-cylinder unit.
  • axially aligned information carrier section is to be understood to mean that this information carrier section is accessible in the axial direction of the piston-cylinder unit and / or its information can be detected in the axial direction of the piston-cylinder unit.
  • the axially aligned information carrier section has a geometric extension in the axial direction of the piston-cylinder unit, by means of which the detectable information of the axial information carrier section is coded.
  • the axially aligned information carrier section has a geometric extension in the radial direction of the piston-cylinder unit and in the circumferential direction of the piston-cylinder unit.
  • the piston-cylinder unit according to the invention with geometrically predetermined dimensions enables a compact structure and, even with an increased number of information carrier sections, secure attachment to the dispenser and slip-free drive of the piston by the dispenser. Likewise, manufacturing tolerances can be greater and so the manufacture of the piston-cylinder unit according to the invention becomes more cost-effective.
  • the information of the radially aligned information carrier section and the axially aligned information carrier section together specify the type of piston-cylinder unit. If a plurality of radially oriented information carrier sections are present, the information from all radially oriented information carrier sections together can also specify the type of piston-cylinder unit.
  • the type of piston-cylinder unit could thus be identified both by means of a dispenser, which exclusively records the information of the radially oriented information carrier sections, and by means of a dispenser, which records the information of at least one axially oriented information carrier section and at least one radially oriented information carrier section.
  • the information carrier sections can together be a sub-type, so z. Specify a purpose, condition, or property, for example. However, it is also possible for the information carrier sections to each specify a sub-type separately. Thus, an information carrier section can be of a sub-type, e.g. B. one property, and another information carrier section another sub-type, e.g. B. specify a state. It can also be the case that the information carrier sections each specify an expression of the same subtype, that is to say one information carrier section has a first property and another information carrier section a second property.
  • the axially oriented information carrier section and the radially oriented information carrier section or all of them Information carrier sections provided on a piston head of the piston-cylinder unit.
  • Both information carrier sections can be arranged so as to overlap in the axial direction.
  • the term "piston head” denotes that part of the piston of the piston-cylinder unit which is located outside the cylinder when the piston is pushed maximally into the cylinder.
  • the dispenser drive acts on the piston head.
  • the axially aligned information carrier section is formed by a recess, in particular a groove, running in the axial direction of the piston-cylinder unit in the piston head.
  • the recess extends in the axial direction from one end face of the piston head. In this way, recesses of a comparatively great depth can be realized without significant disadvantages with regard to the stability of the piston.
  • groove is to be understood such that the recess running in the axial direction of the piston-cylinder unit is not completely surrounded by piston head material in the radial direction of the piston-cylinder unit, but is partially open in the radial direction, preferably along the entire length Depth of the recess. Such a configuration makes it easier to clean the recess and offers a simple means of checking.
  • the radially oriented information carrier section is formed by a recess on the piston head running in the radial direction of the piston-cylinder unit and preferably encircling the circumferential direction of the piston-cylinder unit. If there are several radially oriented information carrier sections, the remaining radially oriented information carrier sections are preferably each formed by a recess on the piston head running in the radial direction of the piston-cylinder unit and preferably encircling the circumferential direction of the piston-cylinder unit. In particular in the case of recesses running around the circumference of the piston-cylinder unit, the radially aligned Recesses can be arranged offset from one another on the piston head in the axial direction of the piston-cylinder unit. This enables a configuration that is compatible with piston-cylinder units with exclusively radially oriented information carrier sections.
  • the information carrier sections are preferably designed such that the depth of the axially aligned recess (expansion in the axial direction) and the depth of the radially aligned recess (expansion in the radial direction) specify the type of piston-cylinder unit. This is a simple way of encoding a comparatively large amount of information. In addition, this allows a simple, precise, little error-prone detection of the coded information and thus a simple and inexpensive construction of the detection device of the dispenser.
  • the radially oriented information carrier sections can be designed so that the depth, number, arrangement in the axial direction of the piston-cylinder unit and / or the respective width of the radially oriented recesses (also) the type of piston-cylinder unit specify.
  • the piston head preferably has a fastening section on which a piston actuator of the dispenser can grip the piston head.
  • This fastening section is preferably arranged at least partially separately from the information carrier sections. There can also be an overlap of the fastening section with the information carrier sections.
  • the inventive combination of the axially oriented information carrier section (s) and the radially oriented information carrier section (s) enables a fastening section to be arranged on the piston head in such a way that the piston head is compact and the piston can be adjusted precisely and without substantial deformation of the piston head by means of the piston actuator.
  • the / are preferably / are radial aligned / n information carrier section / s arranged in the axial direction between the end face of the piston head and the fastening section.
  • a piston-cylinder unit as described above can be detachably attached to it by means of a movement running at least substantially in the axial direction of the dispenser.
  • the dispenser according to the invention has a detection device for automatically identifying the type of a piston-cylinder unit attached to the dispenser.
  • the detection device has an axial information reader, by means of which information from an axially aligned information carrier section of the piston-cylinder unit can be detected.
  • the detection device has a radial information reader, by means of which information from a radially oriented information carrier section of the piston-cylinder unit can be detected.
  • the dispenser according to the invention is thus designed in such a way that it can identify the type of piston-cylinder unit attached to it, as described above.
  • the axial information reader and / or the radial information reader is / are preferably designed for electronic, optical, inductive and / or mechanical detection of the information of the axially or radially oriented information carrier section.
  • the axial information reader has a detection element and the detection device is designed such that at least part of the detection element can be inserted in the axial direction into a recess, in particular a groove, in the piston head of the piston-cylinder unit running in the axial direction of the piston-cylinder unit and in this way the depth of this recess can be determined.
  • the detection element is preferably designed in the manner of a plunger and / or pin and / or is spring-loaded, in particular is elastically pretensioned against the insertion direction of the piston-cylinder unit. It is particularly preferred if the dispenser has a locking element with which the detection element can be moved into a release position and can be held or blocked there. As soon as the locking element no longer blocks the detection element, the spring-loaded detection element is moved towards the piston head and finally pressed into the recess of the piston head running in the axial direction. In this case, the axial information reader can e.g. B. determine the distance covered by the detection element by means of a device for position determination.
  • the radial information reader has an in particular spring-loaded projection and the detection device is designed such that at least part of the projection extends in the radial direction of the piston-cylinder unit and preferably encircling the piston-cylinder unit in the circumferential direction, Recess on the piston head of the piston-cylinder unit can be introduced in the radial direction and in this way the presence of this recess can be determined. This enables a simple, precise, little error-prone acquisition of the coded information and thus a simple and inexpensive construction of the acquisition device.
  • the radial information reader preferably has a light barrier with a light beam source and a sensor for detecting light beams from the light beam source, the light barrier being arranged so that the projection of the radial information reader can be led out or into the radially aligned recess of the light barrier is detectable.
  • the piston actuator of the dispenser is advantageously designed in such a way that it can grip the piston head of the piston-cylinder unit on the fastening section.
  • the axial information reader and the radial information reader for attaching the piston-cylinder unit to the dispenser can each be moved into a release position, so that the piston-cylinder unit can be attached to the dispenser in the axial direction, in particular in the dispenser can be used.
  • the piston-cylinder unit can thus be attached to the dispenser in a simple, quick and user-friendly manner without the axial information reader and / or the radial information reader being damaged.
  • the dispenser For moving the detection element and / or the projection out of the release position, the dispenser preferably has a locking element which can be moved in particular in the axial direction of the dispenser, especially against the insertion direction of the piston-cylinder unit.
  • the piston actuator can preferably be moved towards the piston head of the piston-cylinder unit until a stop of the detection device rests against an end face of the piston head.
  • This movement also known as block travel, is used to record a reference point on the piston head side. This reference point marks in particular the starting point for determining the depth of the recess in the axial direction of the piston head.
  • the dispenser preferably has means, in particular a light barrier, for mechanical, electronic, inductive and / or optical detection of the attachment of the piston-cylinder unit to the dispenser. As soon as a successful attachment of a piston-cylinder unit has been recognized, the recording of the information of the information carrier sections can begin.
  • the dispenser according to the invention is preferably a completely autonomous, hand-held and motor-operated device that combines all components in one housing, regardless of location.
  • a drive preferably a motor drive
  • a gear unit that converts the rotary movement of the motor into a longitudinal movement of the piston actuator
  • a Electronics a power supply
  • a coupling device for connecting the piston of the piston-cylinder unit to the piston actuator.
  • the system according to the invention (third aspect of the invention) has a dispenser as described above and a piston-cylinder unit designed as an exchangeable part as described above.
  • the piston-cylinder unit can be releasably attached to the dispenser by means of a movement running at least essentially in the axial direction of the dispenser.
  • the technical effects of the present invention appear both in the piston-cylinder unit (axial and radial coding or axial coding and fastening section on the piston head) and in the dispenser (detection of the axial and radial coding or fastening on the piston head).
  • the invention also influences the piston-cylinder unit in terms of its physical properties and its mode of operation.
  • the piston-cylinder unit embodies an essential part of the concept of the invention.
  • Another (fourth) aspect of the invention relates to a method for identifying the type of an exchangeable piston-cylinder unit for a dispenser.
  • an exchangeable piston-cylinder unit according to the first aspect of the invention and a dispenser with a detection device for automatically identifying the type of piston-cylinder unit attached to the dispenser are used.
  • a dispenser as described above is used.
  • the information can be recorded electronically, optically, inductively and / or mechanically.
  • an axial information reader of the detection device and / or a radial information reader of the detection device are preferably moved into a release position so that the piston-cylinder unit can be attached to the dispenser in the axial direction, in particular in the dispenser can be used.
  • the cylinder of the piston-cylinder unit is advantageously fixed in step a) of the method.
  • a piston head of the piston-cylinder unit is detachably connected to a piston actuator of the dispenser on a fastening section of the piston head.
  • a coupling between the piston actuator and the piston is achieved. It has proven to be advantageous when the fastening section is arranged separately from the two information carrier sections.
  • a piston head-side reference point is detected by generating a relative movement between the piston head of the piston-cylinder unit and the piston actuator.
  • the length of the relative movement can be determined, preferably by means of a device for incremental distance measurement, which can be motor-driven.
  • the piston actuator can be moved towards the piston head until a stop of the piston actuator rests against an end face of the piston head.
  • step c) preferably starting from the piston head-side reference point, a preferably spring-loaded detection element of the axial information reader is inserted at least partially into a recess, in particular a groove, in the piston head running in the axial direction of the piston-cylinder unit.
  • the depth of this recess is determined, preferably by means of a device for determining the position.
  • a preferably spring-loaded projection of the radial information reader is introduced at least partially into a recess on the piston head running in the radial direction of the piston-cylinder unit and preferably encircling the circumferential direction of the piston-cylinder unit and the presence of this recess, preferably by means of a light barrier, definitely.
  • a locking element of the dispenser is preferably moved, preferably in the axial direction of the dispenser.
  • the piston-cylinder unit has at least one, preferably exactly one, the type of piston-cylinder unit partially specifying, axially aligned information carrier portion and an attachment portion.
  • the axially oriented information carrier section and the fastening section are provided on a piston head of the piston-cylinder unit, the fastening section being arranged separately from the axially oriented information carrier section, in particular offset in the axial direction of the piston-cylinder unit.
  • the fastening section is designed in such a way that a piston actuator of the dispenser can grip the piston head on it.
  • This piston-cylinder unit enables the piston head to be fixed in a stable manner by the piston actuator without any significant deformation of the piston head.
  • the axially aligned information carrier section is preferably formed by a recess, in particular a groove, in the piston head running in the axial direction of the piston-cylinder unit.
  • the recess extends in the axial direction from one end face of the piston head.
  • the depth of the recess in the axial direction preferably partially specifies the type of piston-cylinder unit.
  • the fastening section is advantageously arranged in the axial direction below the axially oriented information carrier section, that is to say between the axially oriented information carrier section and the cylinder of the piston-cylinder unit.
  • At least one radially oriented information carrier section which partially specifies the type of piston-cylinder unit and which is preferably arranged separately from the axially oriented information carrier section and / or the fastening section, is preferably also provided on the piston head.
  • the radially oriented information carrier section can be arranged in the axial direction of the piston-cylinder unit between the end face of the piston head or the axially oriented information carrier section and the fastening section.
  • the radially oriented information carrier section and the axially oriented information carrier section can also be arranged partially overlapping in the axial direction of the piston-cylinder unit.
  • the axially oriented information carrier section and / or the radially oriented information carrier section (s) is / are preferably designed as described above for the first aspect of the invention.
  • Fig. 1 shows schematically in a perspective view a preferred embodiment of a piston-cylinder unit 1 according to the invention for a dispenser 2.
  • the piston-cylinder unit 1 has an in Fig. 1 shown axial direction A k and radial direction R k .
  • the piston-cylinder unit 1 is designed as an exchangeable part. It can be designed in the form of a syringe and be available in different sizes with different receiving volumes. It has a cylinder 3 in which a sealed piston 4 can be moved for the purpose of sucking in and ejecting a liquid to be pipetted or dosed.
  • the piston 4 has a piston rod 5, at one end of which protrudes from the cylinder 3, a piston head 6 is attached. In Fig. 1 of the piston 4, only the piston head 6 is visible.
  • the piston-cylinder unit 1 has two radially oriented information carrier sections 7 partially specifying the type of piston-cylinder unit 1 and exactly one axially oriented information carrier section 8 partially specifying the type of piston-cylinder unit 1.
  • the radially aligned information carrier sections 7 and the axially aligned information carrier section 8 are arranged on the piston head 6.
  • the radially aligned information carrier sections 7 are each formed by a recess 9 on the piston head 6 running in the radial direction R k of the piston-cylinder unit 1 and encircling the circumferential direction of the piston-cylinder unit 1.
  • the radially aligned information carrier sections 7 are arranged offset from one another in the axial direction A k. You can choose between an upper (in Fig. 1 on the outside left on the piston head 6) and a lower one (in Fig. 1 A distinction can be made between radially oriented information carrier section 7 arranged further to the right on piston head 6.
  • the axially aligned information carrier section 8 is formed here by a recess 10 of the piston head 6 running in the axial direction A k of the piston-cylinder unit 1.
  • the axially aligned recess 10 extends in the axial direction A k starting from an end face of the piston head and is upward in the axial direction A k , in Fig. 1 so towards the left at an angle, open.
  • Fig. 2 the piston head 6 is shown schematically enlarged in a perspective view. It can be seen there that the radially aligned recesses 9 are formed in that the piston head has a smaller diameter in these sections.
  • the respective depth or extent in the radial direction R k of the radially aligned recesses 9 can only assume a certain value, here approximately 5 mm. It is therefore the case that the radially aligned recesses 9 are either present or not at a specific position in the axial direction A k. This also means that a depth of 0 mm is not a radially oriented recess in the sense of the present invention.
  • Piston-cylinder units 1 of different types can differ, inter alia, in the depth, number, arrangement in the axial direction A k and / or the respective width (extension in the axial direction A k ) of the radially aligned recesses 9.
  • the axially aligned information carrier section 8 is designed here as an axially aligned recess 10 in the form of a groove. It is therefore not a question of a bore that is enclosed in the radial direction R k. Rather, the axially aligned recess 10 is partially open to the outside in the radial direction R k, namely along the entire depth of the recess 10. Alternatively, the axially aligned recess 10 can be designed as a blind hole.
  • the recesses 9 are designed such that the depth, number, arrangement in the axial direction A k and the respective width of the radially aligned recesses 9 specify the type of piston-cylinder unit 1.
  • the type of piston-cylinder unit 1 is specified in the depth (extension in the axial direction A k ) of the axially aligned recess 10 and the information as to whether or not a radially aligned recess 9 is present in a certain axial region of the piston head 6.
  • piston-cylinder unit 1 can thus be identified both by means of a dispenser, which exclusively records the information from the radially oriented information carrier sections 7, and by means of a dispenser according to the invention.
  • the depth of the axially aligned recess 10 can take one of several discrete values, e.g. B. one of eight possible depth values.
  • the discrete depth values have a minimum distance, preferably approximately 2 mm.
  • a depth of 0 mm is not an axially aligned recess in the sense of the present invention.
  • the axially aligned recess 10 extends in the axial direction A k only over part of the piston head 6. This allows the piston head 6 to be gripped in a stable manner without significant deformations of the piston head 6.
  • the two radially oriented information carrier sections 7 and the axially oriented information carrier section 8 partially overlap. In the case of the recesses 9 and the groove 10, this is dependent on the depth of the axially aligned groove 10 and the distance between the radially aligned recesses 9 and the end face of the piston head 6.
  • the piston head 6 has a fastening section 11 on which a piston actuator 26 of the dispenser 2 can grip the piston head 6.
  • This fastening section 11 is here arranged separately from the information carrier sections 7, 8, namely in the axial direction A k below the radially oriented information carrier section 8. There is no overlap of the fastening section 11 with the information carrier sections 7, 8 here.
  • the piston-cylinder unit 1 according to the invention enables a compact design, downward compatibility with older piston-cylinder units and precise adjustment of the piston 4 by means of the piston actuator 26 without significant deformation of the piston head 6.
  • Fig. 3 shows schematically in a perspective view a preferred embodiment of a dispenser 2 according to the invention.
  • the dispenser 2 has an in Fig. 3 shown axial direction A d .
  • the dispenser 2 has a detection device for automatically identifying the type of piston-cylinder unit 1 attached to the dispenser 2.
  • the detection device has a radial information reader 12 by means of which information from the radially oriented information carrier sections 7 of the piston-cylinder unit 1 can be detected.
  • the detection device has an axial information reader 13, by means of which information from the axially aligned information carrier section 8 of the piston-cylinder unit 1 can be detected. By means of the detection device, the dispenser 2 can identify the type of piston-cylinder unit 1 attached to it.
  • Fig. 4 shows schematically a longitudinal section through a preferred embodiment of a system 14 according to the invention with the dispenser 2 and of the piston-cylinder unit 1 inserted in the dispenser 2 in a first state.
  • the dispenser 2 is only partially shown.
  • Fig. 4 is limited to the representation of those components that are necessary to explain the present invention.
  • the piston 4 has a piston mandrel 28 which is inserted into a tip 29 of the piston-cylinder unit 1 in the case of FIG Fig. 3 End position shown protrudes in order to minimize the dead volume.
  • the cylinder 3 has a flange 30 which rests against a stop element 32 of the dispenser 2. With this and with the aid of a fixing device (not shown), the cylinder 3 is fixed on the dispenser 2, so that only the piston 4 in the cylinder 3 can be moved with respect to the piston-cylinder unit 1 for sucking in and ejecting liquid.
  • the axial information reader 13 has a detection element 15 and the detection device is designed so that part of the detection element 15 can be inserted into the axially aligned groove 10 of the piston-cylinder unit 1 in the axial direction A k and in this way the The depth of this groove 10 can be determined.
  • the detection element 15 is here elastically pretensioned against the insertion direction of the piston-cylinder unit 1 by means of a spring 16.
  • the dispenser 2 has a locking element 17 with which the detection element 15 can be moved into a release position and can be held there. In the release position, the locking element 17 holds the detection element 15 in that a fixing element 18 of the locking element 17 on an extension 19 of the detection element 15 counteracts the force of the spring 16 and a movement of the detection element 15 in the direction of the spring force ( i.e. in the axial direction A d on the piston -Cylinder unit 1 to) blocked.
  • the locking element 17 is displaceable in the axial direction A d in the dispenser 2 and relative to the detection device. By moving the locking element 17 in the direction of the piston-cylinder unit 1 is a Movement of the detection element 15 is no longer blocked, so that the detection element 15 is pressed by the spring 16 towards the piston head 6 and then into the axially aligned recess 10 of the piston head 6 until the detection element 15 hits the end of the recess 10 and blocks there will.
  • the detection device has a device for determining the position of the detection element 15.
  • This device for determining the position comprises a position element 20 which is arranged on the detection element 15 opposite the extension 19.
  • the distance of the relative movement of the detection element 15 towards the piston head 6 can be determined - i.e. the distance that the detection element 15 covers from the release position and / or a reference point on the piston head side to the end of the axially aligned recess 10.
  • the radial information reader 12 has a projection 21 and the detection device is designed so that part of the projection 21 enters the radially oriented recess 9 of one of the two radially oriented information carrier sections 7 of the piston-cylinder unit 1, namely in the lower, radially oriented recess 9, can be introduced in the radial direction R k and in this way the presence of this recess 9 can be determined.
  • the radial information reader 12 has exactly one projection 21 and the projection 21 of the radial information reader 12 can only be moved towards the piston head 6 in a certain axial position in the radial direction R k.
  • the radial information reader 12 cannot read out the information from all radially aligned information carrier sections 7 (inserted into all radially aligned recesses 9). Rather, the radial information reader 12 can detect whether, in the case of a piston-cylinder unit 1 attached to the dispenser, in a specific axial region of the piston head 6 a radially aligned recess 9 is present or not.
  • the radial information reader 12 has a plurality of independently movable projections 21 and / or can be moved towards the piston head 6 at a plurality of axial positions in the radial direction R k.
  • the projection 21 of the radial information reader 12 is elastically pretensioned by means of a spring 22 in the radial direction R k.
  • the locking element 17 By means of the locking element 17, the projection 21 can be moved into a release position and held there. In the release position, the locking element 17 holds the projection 21 in that a link element 23 of the locking element 17 on the radial information reader 12 counteracts the force of the spring 22 and a movement of the projection 21 in the direction of the spring force (i.e. in the radial direction R k towards the piston head 6) blocked.
  • a movement of the projection 21 is no longer blocked, so that the projection 21 is moved towards the piston head 6 by the spring 22. If there is a radially aligned recess 9 in the corresponding axial area of the piston head 6, the projection 21 is pressed into this radially aligned recess 9 of the piston head 6, possibly until the projection 21 hits the end of the recess 9 and is blocked there.
  • a radially oriented recess 9 is present in the corresponding axial region of the piston head 6, namely the lower radially oriented recess 9.
  • the detection element 15 and the projection 21 can be moved into the release position.
  • the piston-cylinder unit 1 can be moved into the dispenser 2 unhindered by the radial information reader 12, in particular its projection 21, and the axial information reader 13, in particular its Detection element 15, inserted or removed in the axial direction A d.
  • the radial information reader 12 has a light barrier 24 with a light beam source and a sensor for detecting light beams from the light beam source.
  • the light barrier 24 is arranged in such a way that the light barrier 24 can detect whether the projection 21 of the radial information reader 12 is inserted into a radially aligned recess 9 of the piston head 6 or not.
  • the light barrier 24 is arranged immovably in the dispenser 2.
  • a web 25 is provided on the radial information reader 12, which is moved synchronously with the projection 21. In the release position of the radial information reader 12, the web 25 interrupts the light barrier 24. This also applies in the event that there is no radially aligned recess 9.
  • the detection device can thus determine whether or not there is a radially oriented recess 9 in the corresponding axial region of the piston head 6.
  • the dispenser 2 has a piston drive device with the piston actuator 26, which is in the Figures 4 to 6 is partially visible.
  • the piston actuator 26 is designed such that it can grip the piston head 6 of the piston-cylinder unit 1 on the fastening section 11.
  • the detection element 15, the spring 16, the extension 19, the projection 21, the spring 22 and the web 25 are movably coupled to the piston actuator 26 or a part of the piston actuator 26.
  • the piston actuator 26 is on the Piston head 6 of the piston-cylinder unit 1 to be movable. The movement takes place at least until a stop 27 of the piston actuator 26 rests against the end face of the piston head 6. This movement is also known as block travel and is used to Acquisition of a reference point on the piston head side. This reference point marks in particular the starting point of a determination of the depth of the axially aligned recess 10 of the piston head 6.
  • the block travel also serves to identify whether the piston 4 has been pushed into the cylinder 3 to the maximum or how far the piston 4 has been pushed into the cylinder 3. With the information from the block travel, the piston 4 can, if necessary, be moved into a starting position, for example, it can be pushed into the cylinder 3 as a maximum.
  • the dispenser 2 has a sensor device for detecting the attachment of the piston-cylinder unit 1 to the dispenser 2.
  • a light barrier 31 is provided here as the sensor device.
  • FIG. 14 schematically shows a longitudinal section through the system 14 from FIG Fig. 4 in a second state. In this second state, the block drive was carried out and ended.
  • FIG. 14 schematically shows a longitudinal section through the system 14 from FIG Fig. 4 in a third state.
  • the detection element 15 is inserted into the axially aligned recess 10 up to its end and the projection 21 is inserted into one of the two radially aligned recesses 9 up to its end.
  • the radial information reader 12 and the axial information reader 13 are moved into the release position so that the piston-cylinder unit 1 can be inserted into the dispenser 2 in the axial direction A d without being obstructed by the radial information reader 12 and the axial information reader 13.
  • the piston-cylinder unit 1 is then releasably inserted into the dispenser 2 by means of a movement running at least substantially in the axial direction A d of the dispenser 2.
  • the cylinder 3 of the piston-cylinder unit 1 is fixed in place. If the piston-cylinder unit 1 has been successfully inserted into the dispenser 2, this is detected by means of the sensor device, in this case the light barrier 31.
  • the piston head-side reference point is then detected by generating a relative movement between the piston head 6 and the piston actuator 26.
  • the piston actuator 26 is moved towards the piston head 6 until the stop 27 of the piston actuator 26 rests on one end face of the piston head 6 (block travel).
  • the length of the relative movement is determined by means of a motor-driven device for incremental distance measurement.
  • the detection element 15 and the projection 21 are moved at least partially overlapping in time, in particular simultaneously, in the axial direction A d towards the piston head 6 during block travel
  • the detection of the piston head-side reference point represents, so to speak, a path calibration for the subsequent detection of the type of inserted piston-cylinder unit 1, which makes the method at least largely independent of differences in the dimensional tolerances of the parts of the piston-cylinder unit 1.
  • the determination of the reference point for each type recognition gives the possibility of defining a starting point for reading out the information from the information carrier sections 7, 8, from which a target is given to the detection device, for example by interposing an unchangeable output variable defined in the dispenser 2 can, for example, from what point in time or what distance after acquisition of the reference point on the piston head side, the acquisition of the information is to be expected or carried out.
  • At least part of the acquisition element 15 of the axial information reader 13 is then inserted into the axially aligned groove 10 of the piston head 6, starting from the reference point on the piston head side.
  • the depth of this groove 10 is determined by means of the position element 20 of the device for position determination.
  • the piston head 6 of the piston-cylinder unit 1 is releasably connected to the piston actuator 26 of the dispenser 2 on the fastening section 11 of the piston head 6. In this way, a coupling between the piston actuator 26 and the piston 4 is achieved.
  • At least part of the projection 21 of the radial information reader 12 is inserted into that radially oriented recess 9 on the piston head 6, which is at the same height as the projection 21 in the axial direction A d, in order to acquire the information of the radially oriented information carrier section 7 of the radial information reader 12 is located.
  • the presence of this recess 9 is determined by means of the light barrier 24.
  • the information readers 12, 13 move at least essentially simultaneously.
  • the coupling of the piston 4 can also take place directly after the block drive.
  • the locking element 17 of the dispenser 2 is moved in the axial direction A d of the dispenser 2 as described above, the fixing element 18 and link element 23 relative to one another are arranged coordinated.

Landscapes

  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Coating Apparatus (AREA)
  • Loading And Unloading Of Fuel Tanks Or Ships (AREA)
  • Pistons, Piston Rings, And Cylinders (AREA)
  • Automatic Assembly (AREA)
EP20207075.1A 2017-02-23 2018-02-22 Austauschbare kolben-zylinder-einheit für einen dispenser Active EP3795254B1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE202017101007.4U DE202017101007U1 (de) 2017-02-23 2017-02-23 Austauschbare Kolben-Zylinder-Einheit für einen Dispenser, Dispenser und System zum Aufnehmen und Abgeben von Fluidvolumina
PCT/EP2018/054386 WO2018153986A2 (de) 2017-02-23 2018-02-22 Verfahren zur erkennung des typs einer austauschbaren kolben-zylinder-einheit für einen dispenser
EP18706741.8A EP3554708B1 (de) 2017-02-23 2018-02-22 Verfahren zur erkennung des typs einer austauschbaren kolben-zylinder-einheit für einen dispenser

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
EP18706741.8A Division EP3554708B1 (de) 2017-02-23 2018-02-22 Verfahren zur erkennung des typs einer austauschbaren kolben-zylinder-einheit für einen dispenser

Publications (2)

Publication Number Publication Date
EP3795254A1 EP3795254A1 (de) 2021-03-24
EP3795254B1 true EP3795254B1 (de) 2021-07-21

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Family Applications (2)

Application Number Title Priority Date Filing Date
EP20207075.1A Active EP3795254B1 (de) 2017-02-23 2018-02-22 Austauschbare kolben-zylinder-einheit für einen dispenser
EP18706741.8A Active EP3554708B1 (de) 2017-02-23 2018-02-22 Verfahren zur erkennung des typs einer austauschbaren kolben-zylinder-einheit für einen dispenser

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Country Link
US (1) US10870107B2 (zh)
EP (2) EP3795254B1 (zh)
CN (1) CN110300627B (zh)
DE (1) DE202017101007U1 (zh)
WO (1) WO2018153986A2 (zh)

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* Cited by examiner, † Cited by third party
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US11471878B2 (en) 2019-10-25 2022-10-18 Mettler-Toledo Rainin, LLC Powered positive displacement pipette
US11446672B2 (en) 2019-10-25 2022-09-20 Mettler-Toledo Rainin, LLC Powered positive displacement pipette syringe piston grasping mechanism
US11389792B2 (en) * 2019-10-25 2022-07-19 Mettler-Toledo Rainin, LLC Syringe for powered positive displacement pipette
US11911767B2 (en) 2019-10-25 2024-02-27 Mettler-Toledo Rainin, LLC Positive displacement pipette syringe identification system
EP3831486A1 (de) * 2019-12-06 2021-06-09 Eppendorf AG Pipettenspitzenfamilie umfassend pipettenspitzen für den gebrauch mit pipetten einer pipettenfamilie und pipettenfamilie umfassend pipetten für den gebrauch mit pipettenspitzen einer pipettenspitzenfamilie
PL3932557T3 (pl) * 2020-07-02 2024-05-13 Eppendorf Se Wielokanałowa głowica do pipetowania

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Also Published As

Publication number Publication date
CN110300627B (zh) 2022-05-10
WO2018153986A3 (de) 2018-10-18
US20190160458A1 (en) 2019-05-30
EP3795254A1 (de) 2021-03-24
EP3554708A2 (de) 2019-10-23
CN110300627A (zh) 2019-10-01
WO2018153986A2 (de) 2018-08-30
US10870107B2 (en) 2020-12-22
EP3554708B1 (de) 2020-11-18
DE202017101007U1 (de) 2018-05-24

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