EP3406236B1 - Dispositif de dosage de poches de perfusion à usage médical ainsi que dispositif de remplissage d'une pluralité de récipients vides - Google Patents

Dispositif de dosage de poches de perfusion à usage médical ainsi que dispositif de remplissage d'une pluralité de récipients vides Download PDF

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Publication number
EP3406236B1
EP3406236B1 EP18172281.0A EP18172281A EP3406236B1 EP 3406236 B1 EP3406236 B1 EP 3406236B1 EP 18172281 A EP18172281 A EP 18172281A EP 3406236 B1 EP3406236 B1 EP 3406236B1
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EP
European Patent Office
Prior art keywords
arrangement
valve
disposed
tube
drive unit
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EP18172281.0A
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German (de)
English (en)
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EP3406236A1 (fr
Inventor
Marc Holthaus
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Metallform Werkzeugbau & Co KG GmbH
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Metallform Werkzeugbau & Co KG GmbH
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/002—Compounding apparatus specially for enteral or parenteral nutritive solutions

Definitions

  • the invention relates firstly to a device for dispensing infusion bags for medical purposes from a limited plurality of components stored in separate containers, which are automatically supplied in the desired amounts to the infusion bag, with a plurality of drive units detachable with liquid transport devices, such as Syringes, roller pumps, can be connected, wherein the containers and the drive units and the drive units and the infusion bag are connected to tubing, in each of which a check valve is arranged and at least one drive unit, in which a multiple valve arrangement for further component container is arranged detachably movable connected, and the multiple valve arrangement is connected to an infusion bag and a drive unit via in each case a hose line, wherein the device for liquid transport in a further drive unit it is arranged.
  • a device for dispensing infusion bags for medical purposes from a limited plurality of components stored in separate containers, which are automatically supplied in the desired amounts to the infusion bag, with a plurality of drive units detachable with liquid transport devices, such as Syringes, roller
  • a similar device is for example from the US 2016/0310920 A1 known.
  • the liquids are guided by means of hose lines via at least one multiple valve arrangement in the infusion bag.
  • the object of the invention is now to provide a new device for dosing infusion bags for medical purposes, with which it is possible, even the above-described multiple metering pumps according to the prior art at the same time for a clear to use larger number of different components at the same time.
  • Apparatus for dispensing infusion bags for medical use from a limited plurality of components stored in separate containers, which are automatically supplied to the infusion bag in the desired amounts, with a plurality of drive units detachably connected to liquid transport devices such as syringes, roller pumps can be, wherein the containers and the drive units and the drive units and the infusion bag are connected to tubing, in each of which a check valve is arranged and at least one drive unit, in which a multiple valve arrangement for further container for components is arranged releasably movable connected, and the multiple valve arrangement with an infusion bag and a drive unit is connected via a respective hose line, wherein the device for liquid transport is arranged in a further drive unit, characterized en n moral that the clamping unit mounted on the drive unit multiple valve assembly of a tube assembly with shell-side flow channel and a plurality of valve bodies arranged on the tube assembly is formed, which are connected on both sides with protective tubes, wherein
  • the main advantage of the device according to the invention is that it is possible according to the invention in a simple and safe way to automatically fill infusion bags with a significantly larger number of different components in certain proportions, including this, the processor-controlled multiple metering pumps according to the prior Technology can be used. It is thus possible, for example, to use up to 16 components with a quadruple dosing pump according to the prior art for dosing an infusion bag. On advantageous Thus, the multiple dosing pump according to the prior art must be converted only by a software change.
  • the multi-valve arrangement clamped on the drive unit consists of a two-piece pipe arrangement connected by an intermediate piece, wherein the intermediate piece includes a flow channel, and on the other hand a plurality of valve bodies arranged on the pipe arrangement, which have protective pipes on both sides are connected, wherein the tube assembly relative to the stationary unit of valve bodies and thermowells slidably disposed, and that each valve body is connected to a container and the tube assembly with a device for liquid transport, such as syringe, roller pump, each via a hose line.
  • a device for liquid transport such as syringe, roller pump
  • the individual valve body of the multiple valve assembly and the pipe assembly outside the valve body corresponding outer codings, such as color, structures, and in addition to the drive unit facing protective tube a viewing window, wherein in the viewing window, the outer coding of each in use valve body is visible ,
  • This device has safety advantages due to the outer coding.
  • the invention also relates to a device for filling a plurality of empty containers from a larger storage container for medical purposes.
  • the object of the invention in this case is to provide a simply constructed device create, with the largest possible number of empty containers can be filled from a larger reservoir.
  • Means for filling a plurality of empty containers from a larger storage container for medical purposes characterized in that at least in a drive unit, a multiple valve arrangement for further containers for components is arranged detachably movable connected, and the multiple valve arrangement with numerous empty containers and a device for liquid transport via a respective hose line is connected and mounted on the drive unit clamping multi-valve arrangement of a tube assembly with mantel workedem flow channel and arranged on the tube assembly plurality of valve bodies, which are connected on both sides with protective tubes, wherein the tube assembly relative to the stationary unit of valve bodies and thermowells is slidably disposed, and wherein each valve body having a container for a component and the tube assembly with a device for liquid transport , like syringe, roller pump, each connected via a hose line
  • the device according to the invention has the significant advantage that one can hereby fill a large number of empty containers in a very simple and effective manner from a storage container.
  • Fig. 1 is a device A for the dosage of infusion bags B for medical purposes from a limited plurality of in separate Containers C stored components shown. It can be seen that the device A is formed from a housing D, on which four drives E for syringes F are arranged. Between the syringes F and in each case a container C for a component, a hose G and a non-illustrated check valve is arranged. In addition, each syringe F with another hose H (also provided with not shown check valve) connected to a manifold I, which in turn is connected via a hose J with the infusion bag B.
  • hose H also provided with not shown check valve
  • the respective motor of the drives E and an electronic control device is arranged in a manner not shown. With the help of the drives E from each container C for a component aspirated a desired amount and fed in a second step on the manifold I and the corresponding hose J to the infusion bag B.
  • a device 10 according to the invention for the dosing of infusion bags 11 for medical purposes from a limited plurality of components stored in separate containers 12 is shown.
  • the device 10 is formed from a housing 13 and a rear foot 14 arranged thereon.
  • the front side 15 of the housing 13 is provided with four drive units 16a-d for syringes 17a-d, on which the syringes 17a-d are arranged, wherein the drive units 16a-d can each be moved vertically upwards and downwards.
  • Above the drive units 16 each additional clamp 18 are attached to the syringes 17 on the front side 15.
  • hoses 19 In a manner not shown are in the housing 13, inter alia, motors for the drive units 16 and an electronic control device arranged. From the syringes 17a and 17b lead hoses 19 to containers 12 for different medical components.
  • the syringes 17a and 17b are connected on the top side in each case via a hose line 20 to a collecting channel 21, wherein said syringe 17a also has a connection to the infusion bag 11 by means of the hose line 20.
  • check valves R are installed (s. Fig. 3
  • a first step the removal of a certain amount of a component from the container 12 or, in a second step, the transport of this quantity via the collection channel 21 to the infusion bag 11 ensure (see flow arrows S).
  • the drive units 16a-d and thus the syringes 17a-d are controlled via the electronic control device, not shown. This means that a syringe 17 first sucks a certain amount, which is then pressed into the infusion bag 11. Thereafter, the second syringe 17 is driven.
  • a multiple valve arrangement 22 is arranged, which has a total of four valve body 23, which are connected to each other by clamping.
  • the multiple valve assembly 22 is enlarged in detail in the Fig. 4 and 5 shown.
  • the multiple valve arrangement 22 is formed from two clear plastic tubes 24, which at the end face each other via an intermediate piece 25 which has a flow channel 26 (s. Fig. 5 ), is clamped.
  • the aforementioned valve body 23 are arranged approximately centrally on the outer circumferential surface of the tube 24 and the intermediate piece 25 and also have protective tubes 27 on both sides, which are also connected by clamping to the valve body 23.
  • Each of the valve body 23 is provided with a flow inlet 29 to which via a respective hose line 30 - as in Fig. 5 shown - container 12 can be arranged for various medical components.
  • the tube 24 is arranged clampingly on the drive unit 16c.
  • a hose line 28 is attached, which leads to a syringe 17d, which is arranged in the region of the drive 16d.
  • the unit of valve body 23 and protective tube 27 in a clamping holder 18 (s. Fig. 2 ) attached.
  • FIG. 5 - A schematic sketch - can be seen above the multiple valve assembly 22, the black box-like, the function of a pump having syringe 17d and the tubing 30 and the collection tube 20/21, which lead to the infusion bag 11.
  • Each valve body 23 has on the inside of the multiple valve assembly 22 - directed to the tube 24 - a spacer 31 and on both sides thereof each O-ring seals 32.
  • the lower tube 24 is provided with color marks 33, which are each assigned to certain valve bodies 23, the outer clamping body 35 with color marks, not shown - have. This means that when a valve body 23 is used with a specific color marking, in a viewing window 37 of the lower protective tube 27, the corresponding corresponding color appears.
  • the illustrated device 10 is a quadruple metering pump, with the principle only an infusion bag 11 with medical Components from four containers 12 can be filled in the desired proportions.
  • the capacity of the quadruple metering pump can be extended to a total of six containers 12 with different components.
  • FIG. 6a and 6b or 7a and 7b and 8 and 9 a further embodiment of a multiple valve assembly 22 with a total of eight valve bodies 23.1 - 8 shown.
  • valve assemblies 22 When arranging two such valve assemblies 22 in the in Fig. 2 illustrated device would be in a manner not shown, the capacity of the quadruple metering pump on sixteen containers 12 with different medical components expandable, the sixfold, ninefold or twelvefold metering pump, in conjunction with a plurality of valve assemblies 22 would still have a significant larger total capacity ,
  • each valve body 23.1-8 is provided with an outer clamping body 35.1-8 having different graphic structures.
  • a medical component is aspirated in the desired amount. Accordingly, a corresponding graphical marking 36.1 appears in a viewing window 37 of the protective tube 27.
  • a relative movement between the tube arrangement 24/25 and the valve arrangement 23/27 has resulted from a movement of the drive unit 16, since the valve arrangement 23/27 in the region of the protective tube 27 by a housing 13 arranged on the clamp holder 18 (s. Fig. 2 ) is held.
  • the container 12.2 is also connected via a hose 30, the flow passage 26 having adapter 25, the tube 24 and the tubing 28 with a syringe 17, which feeds the stored in the container 12.2 medical component in the desired amount to the infusion bag 11.
  • a graphic structure 36.2 corresponding to the external clamping body 35.2 can be recognized.
  • the operator of a device 10 can see at a glance that a medical component is being supplied to the infusion bag 11 from the container 12.
  • Fig. 8 and 9 each show an enlarged sectional view of the in Fig. 7b marked with VIII, the section according to Fig. 8 corresponds to the drawing 7b, while the sectional view according to Fig. 9 Although in the Fig. 7b marked with VIII, but has a different sectional plane.
  • the intermediate piece 25 has a clamping projection 38 which engages in the left tube 24 and a further clamping projection 39 (s. Fig. 9 ), which engages in the right tube 24.
  • each valve body 23.1-8 has a tubular projection 40 on the one hand and on the opposite side an annular cavity 41, wherein each of the tubular projection 40 is inserted by clamping into the annular recess 41.
  • the dead volume ie the volume located in the supply lines always remains constant, since in certain positions of the multiple valve assembly 22, the hose 28 also drawn into the upper tube 24 become can. This is very important for an accurate automatic dosage of the portions for the infusion bag 11.

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  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Claims (4)

  1. Dispositif (10) de dosage de poches de perfusion (11) à des fins médicales à partir d'une pluralité limitée de composants stockés dans des contenants (12.12.1-12.8) séparés, qui sont amenés automatiquement et respectivement dans les quantités souhaitées à la poche de perfusion (11), avec une pluralité d'unités d'entrainement (16, 16a-d), qui peuvent être reliées de manière amovible à des dispositifs pour le transport de fluide, comme des seringues, des pompes à galets, les contenants (12, 12.1-12,8) et les unités d'entrainement (16, 16a-d) ainsi que les unités d'entrainement (16, 16a-d) et la poche de perfusion (11) étant reliés à des conduits flexibles (19, 20, 30), dans lesquels à chaque fois, un clapet anti-retour (R) est disposé, et au moins une unité d'entrainement (16, 16a-d), dans laquelle un agencement de soupapes multiples (22) est disposé pour d'autres contenants (12, 12.1-12.8) pour des composants, de manière amovible et de manière solidaire en déplacement, et l'agencement de soupapes multiples (22) étant relié à une poche de perfusion (11) et à une unité d'entrainement (16, 16a-d) par le biais à chaque fois d'un conduit flexible (19, 20, 30), le dispositif (17, 17a-d) étant disposé pour le transport de fluide dans une autre unité d'entrainement (16, 16a-d), caractérisé en ce que l'agencement de soupapes multiples (22), placé par serrage au niveau de l'unité d'entrainement (16, 16a-d) est formé d'un agencement de tubes (24, 25), avec un canal d'écoulement (26) côté enveloppe et d'une pluralité, disposée sur l'agencement de tubes (24, 25), de corps de soupape (23, 23.1-8), qui sont reliés des deux côtés à des tubes de protection (27), l'agencement de tubes (24, 25) étant disposé mobile par rapport à l'unité stationnaire à partir des corps de soupape (23) et tubes de protection (27), et chaque corps de soupape (23, 23.1-8) étant relié à un contenant (12, 12.1-12.8), ainsi que l'agencement de tubes (24, 25) à un dispositif (17, 17a-d) pour le transport de fluide, comme des seringues, des pompes à galets, à chaque fois par le biais d'un conduit flexible (19, 20, 30).
  2. Dispositif (10) selon la revendication 1, caractérisé en ce que l'agencement de soupapes multiples (22), placé par serrage au niveau de l'unité d'entrainement (16, 16a-d) est composé d'un agencement de tubes (24, 25) en deux parties, relié au moyen d'une pièce intermédiaire (25), la pièce intermédiaire (25) comprenant un canal d'écoulement (26) d'une part, et comporte une pluralité, disposée sur l'agencement de tubes (24, 25), de corps de soupape (23, 23.1-8) qui sont reliés des deux côtés à des tubes de protection (27), d'autre part, l'agencement de tubes (24, 25) étant disposé mobile par rapport à une unité stationnaire à partir de corps de soupape (23, 23.1-23.8) et tubes de protection (27), et en ce que chaque corps de soupape (23) est relié à un contenant (12, 12.1-12.8), ainsi que l'agencement de tubes (24, 25) à un dispositif (17, 17a-d) pour le transport de fluide, comme des seringues, des pompes à galets, à chaque fois par le biais d'un conduit flexible (19, 20, 30).
  3. Dispositif (10) selon l'une des précédentes revendications, caractérisé en ce que les corps de soupape individuels (23) de l'agencement de soupapes multiples (22) et l'agencement de tubes (24, 25) sont munis à l'extérieur des corps de soupape (23, 23.1-8) de codages extérieurs (33, 36.1-8) correspondants, comme des couleurs, structures, et en ce que le tube de protection (27), pointant en direction de l'unité d'entrainement (16, 16a-d), comporte une fenêtre de visualisation (37), le codage extérieur de chaque corps de soupape (23, 23.1-8), respectivement utilisé, est visible dans la fenêtre de visualisation (37).
  4. Dispositif pour le remplissage d'une pluralité de contenants vides depuis un contenant de stockage plus grand à des fins médicales, caractérisé en ce qu'au moins dans une unité d'entrainement (16, 16a-d), est disposé un agencement de soupapes multiples (22) pour d'autres contenants (12, 12.1-12.8) pour des composants, de manière amovible et de manière solidaire en déplacement, et en ce que l'agencement de soupapes multiples (22) est relié à de nombreux contenants vides et à un dispositif (17, 17a-d) pour le transport de fluide par le biais à chaque fois d'un conduit flexible (19, 20, 30) et l'agencement de soupapes multiples (22), placé par serrage au niveau de l'unité d'entrainement (16, 16a-d) est formé d'un agencement de tubes (24, 25), avec un canal d'écoulement (26) côté enveloppe et une pluralité, disposée sur l'agencement de tubes (24, 25), de corps de soupape (23, 23.1-8) qui sont reliés des deux côtés à des tubes de protection (27), l'agencement de tubes (24, 25) étant disposé mobile par rapport à l'unité stationnaire à partir de corps de soupape (23) et tubes de protection (27), et chaque corps de soupape (23, 23.1-8) étant relié à un contenant (12, 12.1-12.8) pour un composant, ainsi que l'agencement de tubes (24, 25) à un dispositif (17, 17a-d) pour le transport de fluide, comme des seringues, des pompes à galets, à chaque fois par le biais d'un conduit flexible (19, 20, 30).
EP18172281.0A 2017-05-23 2018-05-15 Dispositif de dosage de poches de perfusion à usage médical ainsi que dispositif de remplissage d'une pluralité de récipients vides Active EP3406236B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102017111207.3A DE102017111207B3 (de) 2017-05-23 2017-05-23 Vorrichtung zur Dosierung von Infusionsbeuteln für medizinische Zwecke sowie Einrichtung zur Befüllung einer Mehrzahl von Leerbehältern

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EP3406236A1 EP3406236A1 (fr) 2018-11-28
EP3406236B1 true EP3406236B1 (fr) 2019-11-06

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EP18172281.0A Active EP3406236B1 (fr) 2017-05-23 2018-05-15 Dispositif de dosage de poches de perfusion à usage médical ainsi que dispositif de remplissage d'une pluralité de récipients vides

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EP (1) EP3406236B1 (fr)
DE (1) DE102017111207B3 (fr)
ES (1) ES2773038T3 (fr)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10149935B2 (en) * 2006-11-27 2018-12-11 Frank Levy Delivery system and method for the effective and reliable delivery of controlled amounts of a medical fluid
US11357966B2 (en) 2015-04-23 2022-06-14 B. Braun Medical Inc. Compounding device, system, kit, software, and method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
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Publication number Publication date
EP3406236A1 (fr) 2018-11-28
ES2773038T3 (es) 2020-07-09
DE102017111207B3 (de) 2018-08-30

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