EP2662065A1 - Verblindungsvorrichtung - Google Patents
Verblindungsvorrichtung Download PDFInfo
- Publication number
- EP2662065A1 EP2662065A1 EP13164845.3A EP13164845A EP2662065A1 EP 2662065 A1 EP2662065 A1 EP 2662065A1 EP 13164845 A EP13164845 A EP 13164845A EP 2662065 A1 EP2662065 A1 EP 2662065A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- container
- lid
- blinding
- center part
- opening
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000005070 sampling Methods 0.000 claims abstract 5
- 238000002360 preparation method Methods 0.000 claims description 8
- 238000007789 sealing Methods 0.000 abstract 2
- 239000002775 capsule Substances 0.000 description 4
- 230000007704 transition Effects 0.000 description 4
- 201000004569 Blindness Diseases 0.000 description 1
- 244000197960 Galium verum Species 0.000 description 1
- 230000004323 axial length Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000902 placebo Substances 0.000 description 1
- 229940068196 placebo Drugs 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1412—Containers with closing means, e.g. caps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/16—Holders for containers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D51/00—Closures not otherwise provided for
- B65D51/18—Arrangements of closures with protective outer cap-like covers or of two or more co-operating closures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D77/00—Packages formed by enclosing articles or materials in preformed containers, e.g. boxes, cartons, sacks or bags
- B65D77/04—Articles or materials enclosed in two or more containers disposed one within another
- B65D77/048—Articles or materials enclosed in two or more containers disposed one within another the inner and outer containers being rigid and the outer container being of curved cross-section, e.g. cylindrical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1406—Septums, pierceable membranes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D2251/00—Details relating to container closures
- B65D2251/0003—Two or more closures
- B65D2251/0006—Upper closure
- B65D2251/0015—Upper closure of the 41-type
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D2251/00—Details relating to container closures
- B65D2251/0003—Two or more closures
- B65D2251/0068—Lower closure
- B65D2251/0078—Lower closure of the 41-type
Definitions
- the invention relates to a device for blinding containers for clinical studies.
- test subjects can optically not distinguish between different preparations.
- different preparations i. ie e.g. Verum and placebo
- the preparation containers are provided with an additional marking, for example a colored closure cap, the known blindness measures are not sufficient.
- container or small container vials are used, in which usually preparations, i. usually liquid drugs, are provided for clinical trials.
- the blinding sheath described herein is a rigid, hard shell shell, in contrast to known easily deformable sheaths.
- the blinding sheath 1 for a container 2 consists of a middle part 3, a bottom 4 inserted at the lower end of the middle part and a lid 5 arranged on the upper side of the middle part 5.
- the central part 3 has a cylindrical lower portion with a diameter which is larger than the diameter of the container.
- the middle part is tapered to a smaller diameter.
- the upper area is offset laterally with respect to the axis of the lower area with its axis. in such a way that the transition between the lower and the upper region of the central part is strong on one side, left in the figures, and only slightly inclined in relation to each other. In between, there is a uniform course of the slope.
- a circumferential groove 6 On the outside of the upper portion of the central part of a circumferential groove 6 is formed, which is provided on the side of the steeply inclined transition and opposite each with a downward branch. The function of this groove and its branches will be described below together with the function of the lid 5.
- the container is arranged eccentrically on the side of the steeply inclined transition of the middle part.
- a support in the manner of a false bottom 7 with an opening 8 and a circumferential, downwardly directed skirt 9, which is on the side of the steeply inclined transition into the wall of the upper area passes.
- Through the opening extends the neck of the container with its tapered area being held by the lower edge of the skirt.
- the underside of the container is fixed in this position by the bottom 4, which for this purpose on the one hand has an upward thickening 10, through which the container is pressed up against the lower edge of the skirt, and on the other hand with an upstanding Edge 11 is provided for lateral fixation of the container.
- the bottom is pressed after the introduction of the container in the lower opening of the middle part.
- Containers whose diameter over their entire axial length is not or only slightly larger than that of the closure capsule can not be fixed in this way in the shell.
- suitable webs can be arranged inside the casing and / or the casing can consist, for example, of two half-shells separated in the longitudinal direction.
- the cover 5 consists of a top cover 12 corresponding to the upper opening of the middle part and a skirt 13 which extends downwards and embraces the upper edge of the middle part. Near the lower edge of the skirt two inwardly directed cams 14 are arranged, arranged opposite one another. which engage in the groove 6 described above. By this engagement, the lid is connected to the middle part. As the cams engage the downward branches, the lid can be moved axially with respect to the central portion. In its upper position, the lid can be rotated relative to the central part by the cams are guided in the circumferential groove.
- a plurality of gripping elements 15 are mounted in the form of hooks which engage under the cap of the container.
- a removal point in the present case provided with a tubular downwardly extending extension 17 through opening 16, for a removal needle for removal of a Amount of preparation from the container.
- the through-opening can be closed by an elastic plug or the like, which is pierced with the needle for removal.
- FIG. 1 The arrangement shown represents the situation of the blinded container for storage, transportation, etc., ie for the provision for the purpose of a clinical study.
- the cams of the lid are located at the lower ends of the branches of the circumferential groove.
- the lid, as in Fig. 2 shown as far as raised until the cams 14 to the height of the revolving Pass groove.
- the cap With the lifting of the lid, the cap is lifted off the container by the gripping elements.
- the next step is to remove the lid with the capsule removed from the container, as in Fig.
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Closures For Containers (AREA)
- Sewing Machines And Sewing (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
Description
- Die Erfindung betrifft eine Vorrichtung zum Verblinden von Behältern für klinische Studien.
- Bekanntlich muss für klinische Studien sichergestellt werden, dass die Probanden unterschiedliche Präparate optisch nicht unterscheiden können. Wenn die unterschiedlichen Präparate, d.h. also z.B. Verum und Placebo, sich in zwar gleichen Behältern befinden, aber optische Unterschiede (Farbe, Konsistenz etc.) aufweisen, genügt es, die Behälter mit einer opaken Umhüllung zu versehen. Wenn aber die Präparatebehälter mit einer zusätzlichen Kennzeichnung, beispielsweise einer farbigen Verschlusskappe, versehen sind, genügen die bekannten Verblindungsmassnahmen nicht.
- Für den Zweck dieser Beschreibung werden die Begriffe Behälter oder Präparatebehälter für kleine Flaschen (engl. Vial) verwendet, in denen üblicherweise Präparate, d.h. in der Regel flüssige Arzneimittel, für klinische Studien bereitgestellt werden.
- Der Erfindung liegt die Aufgabe zugrunde, eine Verblindung von Behältern zu ermöglichen, welche einen gesamten Behälter umfasst und während einer klinischen Studie die Identifikation des Behälters oder seines Inhalts verunmöglicht.
- Erfindungsgemäss wird dies erreicht durch eine Verblindungsvorrichtung mit den kennzeichnenden Merkmalen des Anspruchs 1.
- Im Folgenden wird anhand der beiliegenden Zeichnungen ein bevorzugtes Ausführungsbeispiel der Erfindung beschrieben. Die Zeichnungen zeigen eine erfindungsgemässe Verblindungsvorrichtung und verschiedene Phasen der Öffnung des Behälters zum Zweck der Präparatentnahme, und zwar
- Fig. 1
- eine Schnittdarstellung einer Verblindungshülle mit einem darin befindlichen Behälter in geschlossenem Zustand,
- Fig. 2
- die Verblindungshülle mit vom Behälter abgenommener Verschlusskapsel
- Fig. 3
- die Verblindungshülle mit weggedrehter Verschlusskapsel
- Fig. 4
- die zur Präparatentnahme bereite Position von Behälter und Verblindungshülle.
- Bei der vorliegend beschriebenen Verblindungshülle handelt es sich um eine steife, formstabile (engl. hard-shell) Hülle im Gegensatz zu bekannten leicht verformbaren Umhüllungen.
- Die Verblindungshülle 1 für einen Behälter 2 besteht aus einem Mittelteil 3, einem am unteren Ende des Mittelteils eingesetzten Boden 4 und einem auf der Oberseite des Mittelteils angeordneten Deckels 5.
- Der Mittelteil 3 besitzt einen zylindrischen unteren Bereich mit einem Durchmesser, der grösser ist als der Durchmesser des Behälters. In seinem oberen Bereich ist der Mittelteil auf einen kleineren Durchmesser verjüngt. Ausserdem ist der obere Bereich mit seiner Achse lateral gegenüber der Achse des unteren Bereichs versetzt. derart, dass der Übergang zwischen dem unteren und dem oberen Bereich des Mittelteils auf einer Seite, in den Figuren links, stark und gegenüber nur geringfügig geneigt ist. Dazwischen ergibt sich ein gleichmässiger Verlauf der Neigung.
- An der Aussenseite des oberen Bereichs des Mittelteils ist eine umlaufende Nut 6 ausgebildet, die auf der Seite des stark geneigten Übergangs und gegenüber mit je einer nach unten gerichteten Abzweigung versehen ist. Die Funktion dieser Nut und ihrer Abzweigungen wird nachfolgend zusammen mit der Funktion des Deckels 5 beschrieben.
- Der Behälter ist exzentrisch auf der Seite des stark geneigten Übergangs des Mittelteils angeordnet. Zur Fixierung des Halses des Behälters ist unterhalb des oberen Endes des Mittelteils eine Halterung in der Art eines Zwischenbodens 7 mit einer Öffnung 8 und einer umlaufenden, nach unten gerichteten Schürze 9 ausgebildet, die an der Seite des stark geneigten Übergangs in die Wand des oberen Bereichs übergeht. Durch die Öffnung erstreckt sich der Hals des Behälters, wobei dessen Verjüngungsbereich durch die Unterkante der Schürze gehalten wird.
- Auch die Unterseite des Behälters wird in dieser Position fixiert und zwar durch den Boden 4, der zu diesem Zweck einerseits eine nach oben gerichtete Verdickung 10 besitzt, durch welche der Behälter nach oben gegen die Unterkante der Schürze gedrückt wird, und der andererseits mit einem aufragenden Rand 11 zur seitlichen Fixierung des Behälters versehen ist. Der Boden wird nach dem Einbringen des Behälters in die untere Öffnung des Mittelteils eingepresst.
- Behälter, deren Durchmesser über ihre gesamte axiale Länge nicht oder nur unwesentlich grösser ist als derjenige der Verschlusskapsel, können nicht auf diese Weise in der Hülle fixiert werden. Um sie dennoch axial zu fixieren, können im Inneren der Hülle geeignete Stege angeordnet und/oder die Hülle z.B. aus zwei in Längsrichtung getrennten Halbschalen bestehen.
- Der Deckel 5 besteht aus einem der oberen Öffnung des Mittelteils entsprechenden, ebenen Abdeckteil 12 und einer nach unten gerichteten, den oberen Rand des Mittelteils umgreifenden Schürze 13. Nahe der unteren Kante der Schürze sind zwei einender gegenüber angeordnete, nach innen gerichtete Nocken 14 ausgebildet, die in die weiter oben beschriebene Nut 6 eingreifen. Durch diesen Eingriff ist der Deckel mit dem Mittelteil verbunden. Wenn die Nocken in die nach unten gerichteten Abzweigungen eingreifen kann der Deckel in Bezug auf den Mittelteil axial bewegt werden. In seiner oberen Position kann der Deckel gegenüber dem Mittelteil verdreht werden, indem die Nocken in der umlaufenden Nut geführt werden.
- Auf der Unterseite des ebenen Abdeckteils 12 sind mehrere Greifelemente 15 in der Form von Haken angebracht, welche die Verschlusskappe des Behälters untergreifen. Im gleichen Abstand wie die Achse des Behälters von der Achse des oberen Bereichs des Mittelteils befindet sich, um 180° winkelversetzt angeordnet, eine Entnahmestelle, im vorliegenden Fall eine mit einer rohrförmig nach unten gerichteten Verlängerung 17 versehene Durchgangsöffnung 16, für eine Entnahmenadel zur Entnahme einer Präparatmenge aus dem Behälter. Die Durchgangsöffnung kann je nach Anwendung durch einen elastischen Stopfen oder dergl. verschlossen sein, der zur Entnahme mit der Nadel durchstochen wird.
- Die in
Fig. 1 gezeigte Anordnung stellt die Situation des verblindeten Behälters für Lagerung, Transport etc., d.h. für die Bereitstellung zum Zweck einer klinischen Studie, dar. Die Nocken des Deckels befinden sich an den unteren Enden der Abzweigungen von der umlaufenden Nut. Um eine Präparatmenge zu entnehmen, wird nun ausgehend von der Situation gemässFig. 1 der Deckel, wie inFig. 2 gezeigt, soweit angehoben, bis die Nocken 14 auf die Höhe der umlaufenden Nut gelangen. Mit dem Anheben des Deckels wird durch die Greifelemente die Verschlusskappe vom Behälter abgehoben. Als nächster Schritt wird der Deckel mit der vom Behälter abgenommenen Verschlusskapsel, wie inFig. 3 gezeigt, um 180° verdreht, so dass sich die Verschlusskapsel weitest möglich seitlich von der Öffnung des Behälters und gleichzeitig die Durchgangsöffnung sich über der Öffnung des Behälters befindet. Durch die Drehung um 180° befinden sich die Nocken wieder über den Abzweigungen der Nut, so dass der Deckel, wie inFig. 4 gezeigt, wieder axial nach unten bewegt werden kann, um die erreichte Position zu fixieren.
Claims (1)
- Vorrichtung zum Verblinden von Behältern mit einem zum Zweck der Präparatentnahme zu entfernenden Verschluss, gekennzeichnet durch eine den Behälter vollständig umgebende Verblindungshülle mit einem axial bewegbaren und verdrehbaren Deckel, der mit Mitteln zum Ergreifen des Verschlusses und einer Entnahmestelle für eine Entnahmenadel versehen ist derart, dass durch axiales Bewegen und Verdrehen des Deckels der Verschluss vom Behälter entfernt wird und die Entnahmestelle über den offenen Behälter gelangt.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH00637/12A CH706482A1 (de) | 2012-05-08 | 2012-05-08 | Verblindungsvorrichtung. |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2662065A1 true EP2662065A1 (de) | 2013-11-13 |
EP2662065B1 EP2662065B1 (de) | 2015-03-04 |
Family
ID=47115064
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP13164845.3A Active EP2662065B1 (de) | 2012-05-08 | 2013-04-23 | Verblindungsvorrichtung |
Country Status (5)
Country | Link |
---|---|
US (1) | US9192543B2 (de) |
EP (1) | EP2662065B1 (de) |
CH (1) | CH706482A1 (de) |
DK (1) | DK2662065T3 (de) |
ES (1) | ES2546561T3 (de) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016005740A3 (en) * | 2014-07-07 | 2016-03-24 | Kenneth Simon Aylett Moore | A masking package |
CN107804563A (zh) * | 2017-11-01 | 2018-03-16 | 姚森 | 一种医用滴眼液辅助包装盒 |
CN107822770A (zh) * | 2017-11-01 | 2018-03-23 | 姚森 | 一种医用滴眼液辅助支架 |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11542083B2 (en) | 2019-09-30 | 2023-01-03 | Fisher Clinical Services, Inc. | Vial blinding assemblies and methods of assembly |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU441022B2 (en) * | 1970-07-14 | 1973-09-28 | Fmc Corporation | An improved capsule for containing an article (divisional of 408,028) |
US5590782A (en) * | 1995-04-17 | 1997-01-07 | Habley Medical Technology Corporation | Vial holder assembly |
US20040129596A1 (en) * | 2000-12-06 | 2004-07-08 | Geert Peter Van | Container and a container accessory |
US20070163914A1 (en) * | 2005-09-22 | 2007-07-19 | Gehring Debra G | Package closure |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2438906A (en) * | 1945-04-21 | 1948-04-06 | William D Elsas | Closure |
US2750066A (en) * | 1953-07-10 | 1956-06-12 | Adela F Shekter | Pocket flasks |
US4949858A (en) * | 1989-06-19 | 1990-08-21 | Ethylene Corp. | Sample bottle and cap therefor |
US5143261A (en) * | 1989-12-20 | 1992-09-01 | The Procter & Gamble Company | Multi-compartment container for proportional dispensing of a plurality of liquids |
US8875926B2 (en) * | 2012-03-16 | 2014-11-04 | Valon Grajqevci | Resealable multi-compartment beverage container |
-
2012
- 2012-05-08 CH CH00637/12A patent/CH706482A1/de not_active Application Discontinuation
-
2013
- 2013-04-12 US US13/861,709 patent/US9192543B2/en active Active
- 2013-04-23 DK DK13164845.3T patent/DK2662065T3/en active
- 2013-04-23 ES ES13164845.3T patent/ES2546561T3/es active Active
- 2013-04-23 EP EP13164845.3A patent/EP2662065B1/de active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU441022B2 (en) * | 1970-07-14 | 1973-09-28 | Fmc Corporation | An improved capsule for containing an article (divisional of 408,028) |
US5590782A (en) * | 1995-04-17 | 1997-01-07 | Habley Medical Technology Corporation | Vial holder assembly |
US20040129596A1 (en) * | 2000-12-06 | 2004-07-08 | Geert Peter Van | Container and a container accessory |
US20070163914A1 (en) * | 2005-09-22 | 2007-07-19 | Gehring Debra G | Package closure |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016005740A3 (en) * | 2014-07-07 | 2016-03-24 | Kenneth Simon Aylett Moore | A masking package |
CN107804563A (zh) * | 2017-11-01 | 2018-03-16 | 姚森 | 一种医用滴眼液辅助包装盒 |
CN107822770A (zh) * | 2017-11-01 | 2018-03-23 | 姚森 | 一种医用滴眼液辅助支架 |
CN107804563B (zh) * | 2017-11-01 | 2019-11-12 | 范小丽 | 一种医用滴眼液辅助包装盒 |
Also Published As
Publication number | Publication date |
---|---|
DK2662065T3 (en) | 2015-06-08 |
ES2546561T3 (es) | 2015-09-24 |
US20130299446A1 (en) | 2013-11-14 |
EP2662065B1 (de) | 2015-03-04 |
CH706482A1 (de) | 2013-11-15 |
US9192543B2 (en) | 2015-11-24 |
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