Classifications

• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
  • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
  • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
  • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
  • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
  • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
  • A61J7/0427—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system
  • A61J7/0445—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system for preventing drug dispensing during a predetermined time period
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
  • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
  • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
  • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
  • A61J7/0454—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers for dispensing of multiple drugs
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
  • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
  • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
  • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
  • A61J7/0472—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers of the count-down type, i.e. counting down a predetermined interval after each reset
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
  • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
  • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
  • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
  • A61J7/0481—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers working on a schedule basis
• • G—PHYSICS
  • G06—COMPUTING OR CALCULATING; COUNTING
  • G06F—ELECTRIC DIGITAL DATA PROCESSING
  • G06F3/00—Input arrangements for transferring data to be processed into a form capable of being handled by the computer; Output arrangements for transferring data from processing unit to output unit, e.g. interface arrangements
  • G06F3/14—Digital output to display device ; Cooperation and interconnection of the display device with other functional units
• • G—PHYSICS
  • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
  • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
  • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
  • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
  • G16H20/13—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered from dispensers

Definitions

• the present invention relates to a display device for a dispenser for medicament portions, wherein the medicament portions are to be taken at regularly recurring reference intake times and the display device comprises a display and an electronic control for the display.
• the present invention further relates to the use of this display device for controlling the ingestion of drug portions, in particular hormone preparations portions, especially contraceptive portions, from a donor.
• DE 100 35 5999 A1 describes a pill box with integrated timer.
• the pill box comprises a plurality of compartments for receiving pills, each of which is assigned a light-emitting diode.
• the timer includes a digital display and control buttons for its programming.
• One of the light emitting diodes is at the respective pre-programmed time of taking the pills contained in the associated pill compartment controlled so that the user knows which pills to take.
• acoustic and mechanical signalers are provided.
• DE 20 2004 012 232 U1 describes a so-called pill clock.
• This pill clock has on the one hand a pill box, which is combined with a digital clock. This is to ensure that the user carries the tablets to be taken when he is reminded by the digital clock on the intake.
• the pill box has six compartments for the tablets.
• the digital clock is equipped with a digital display for the current time and six other digital displays, which remind in different modes of taking the tablets in the six compartments of the pill box.
• the pills clock reminds by a countdown display to the respective intake of a tablet.
• the user can be acoustically reminded to take it.
• the pills watch can be worn like a wristwatch on the wrist.
• DE 10 2004 023 641 A1 discloses a device with means for connecting to an anti-baby pill blister.
• the device serves to aid in the correct intake of anti-baby pills throughout the female cycle and, at the same time, should also take into account the non-taking phase.
• the device is designed so that a blister containing the anti-baby pills can be connected to the device, such as a clip or a bag, and optionally additionally a detection means for inserting the blister into the device and / or for removing the Blister is provided by the device.
• detection means for controlling the filling state of the tablet positions may be located in the blister. For example, breaking the foil on the blister to remove an anti-baby pill from a tablet position may activate a timer.
• the device has a display in the form of a digital clock, which indicates the remaining period until the beginning of an alarm signal. Alarm signals can be output via loudspeakers, vibrators or LEDs or the display. The display also shows the user which cycle day she is currently on.
• a further device comprising a computer with a plug contact strip for inserting a tablet blister.
• the tablets blister is suitably designed so that at the points on the film, which are pierced in the removal of a tablet, tracks are so that they are severed when piercing the film, wherein the conductor tracks upon insertion of the blister in the plug contact strip placed on the computer with the plug contacts located there in electrical contact become.
• the computer has a digital display for the current time and / or the time of the next tablet intake.
• an audible signal or LEDs may remind you to take a tablet. A first one of the LEDs is for indicating that one tablet is to be taken, a second one to make one taking too early, and a third to indicate that the taking time has already passed.
• DE 102 17 929 A1 discloses a device for dispensing tablets.
• This device is used to hold blisters and has push button for expressing a tablet from the blister, further means for adjusting intake times and means for displaying the intake times.
• the device is reminiscent of taking a tablet for a preset period of administration. Alarm icons on an LCD display are used for this purpose.
• the device automatically registers the removal of a tablet.
• the devices described above are suitable for automatically remembering the time of taking medicine portions. For this serve in the described donors various different display and alarm means. In individual cases, it is often reminded of the possibly forgotten or consciously missed intake of a portion of medication. However, the user does not have complete knowledge of the revenue status with this information. For example, it usually is not necessary to take a portion of medication at a precisely specified time. Rather, it is sufficient to take the drug portion within a time interval. Although it is stated in DE 20 2004 012 232 U1 for this purpose that an alarm can also be repeated, the user can set how often and at what time interval the alarm should be repeated. However, it does not specify the relationship between this alarm repetition and the actual timeout tolerance and actual timeout.
• the user should be able to quickly and easily recognize the current status of taking medicine portions.
• the intake of hormone preparations, especially of Contraceptives particularly by the user visually presented the required information about the current revenue status at a glance.
• the user should also be able to receive a suggestion for remedies in the event of operating errors and then, if the user forgets to take the medicine portions, quickly and easily and without extensive search in documentation.
• An increased compliance in the drug intake is also to be achieved by the fact that incorrect operations are largely excluded, for example in the event that the user accidentally takes more than one portion of medication, this revenue but not taken into account in the revenue tracking, or a portion of medication does not take, but erroneously posted a revenue in the revenue track.
• the safety of the intake should also be ensured in the long term, ie if medicinal products are taken over a long period of time.
• the display device serves to control the status of the intake of medicament portions by a user. Above all, the status of the intake of hormone preparations and especially of steroid hormone preparations, for example, for contraception, are displayed. But the intake of portions of other medicines should be easily and safely controlled, for example, hormone preparations for hormone replacement therapy.
• the display device for controlling the status of drug portions can also be used for the treatment of all chronic diseases. The use of the display device is then particularly important if the drug portions are to be taken at regularly recurring reference intake times. Therefore, the display device according to the invention should primarily serve to control the status of the intake of contraceptives. In this case, the drug portions must be taken in a regular intake regimen, namely once a day, followed by a multi-day intake phase always a multi-day interruption phase. Failure to comply with the prescribed administration time may result in the desired effect of contraception.
• the display device on a display and an electronic control for the display.
• the display comprises a first visualization means for displaying a first time interval between a first reference administration time and the current time, wherein the first reference administration time is characterized in that no drug portion has been taken until the first reference administration time (although so provided) was).
• reference times are understood as points in time at which the medicament portions should ideally be taken, for example at daily portions of medicaments to be taken on each day, for example at 7:00 or else at 9:00 or at another fixed time
• the revenue interval may for example be from a time 12 hours before the reference administration time to a time for example 2 or even 24 hours after the reference administration time point.
• such a reference administration time and the interval of administration must be determined on each day.
• the reference administration time is preferably calculated from the time of a first withdrawal of a drug portion (from a drug donor), particularly preferably in a taking cycle, and the prescribed repetition rhythm for the intake.
• the respective reference administration times are then calculated from the respective time intervals resulting from the repetition rhythm and the time of the first withdrawal of a medicament portion from the donor, which in turn is identical to the time of the first intake of a medicament portion.
• the reference administration times for drug portions to be taken once a day are in each case 24 hours (n is an integer) after the first removal of the medicament portion from the donor.
• the reference administration times for a drug to be taken twice a day for example, when a first withdrawal and thus intake took place at 7:00 am and a second intake take place 12 hours later should be calculated on each subsequent day at 7:00 and 19:00.
• the reference administration times can also be calculated differently starting from the first withdrawal of the medicament portion from the donor. For example, a reference administration time can be calculated from the last, for example, three actual administration times.
• the display device thus has an indication for a timeout of the first reference administration time, i. a time of taking the medicine portion should be taken, but the user has inadvertently or deliberately failed to take the medicine portion until this first reference administration time.
• the display device having the aforementioned first visualization means for indicating a timeout of the first reference administration time, a comprehensive control of the revenue status of the drug is possible: the display of a timeout allows the user or a doctor to initiate remedial measures, if necessary to compensate for the lack of ingestion. Furthermore, it is also immediately apparent to the user when the time interval for the intake expires, when he / she knows the time interval in which a medication portion has to be taken. Of course, the time interval can also be shown separately in the visualization means, so that the user recognizes at a glance whether he / she is still receiving the medication portion in time, in spite of timeout of the first reference administration time. within the time interval.
• the display device is preferably advantageous for the intake of contraceptives and in this case especially in cases in which the user follows a so-called flexible revenue regime.
• Contraceptives typically need to be taken once a day, with a conventional dose regimen of one 21-day daily portion of medication taken followed by a 7-day interruption period. Subsequently, this intake cycle is repeated again.
• the intake phase may last 24 days and the interruption phase 4 days. It has also been proposed to take contraceptive preparations after a so-called flexible revenue regimen. In this case, the intake phase lasts for at least 24 days (compulsory intake phase) and for a maximum of 120 days, for example.
• a decision on the duration of the intake phase is mentioned in the Leave limits to the user, ie the user can decide at the end of the mandatory intake phase itself, whether it initiates the interruption phase. However, it has to do this until the end of the maximum period of the flexible phase, ie in the mentioned case until the expiry of 120 days.
• the flexible intake phase is typically followed by an interruption period of 4 days.
• this first time span of the timeout after the first reference administration time in this case can be calculated as a period within the interruption phase.
• the present invention therefore also serves in this case to give the user an easy way of deciding to switch from the intake phase to the interruption phase. For example, if the intake time interval is exceeded, the user may decide to start an interruption phase to allow regular intake can be restarted properly after the loss of revenue.
• the display additionally comprises a second visualization means for displaying a second time interval between a second reference administration time and the current time.
• the second reference administration time is characterized in that it is within a predetermined administration time interval and a drug portion has been taken in the predetermined administration time interval.
• the second time span extends maximally up to the second reference administration time point following the first reference administration time. That is, with full scale utilization of the second visualization means, the display extends over the entire period between the second reference administration date and the first reference intake point in case the portion of the drug has not been taken until the first reference intake point or is taken at that exact time.
• the first visualization means is started, which then displays the subsequent first time period since the first reference administration time.
• the representation of the elapsed second time period between the second reference administration time and the first reference administration time preferably remains in this case, but may also be deleted in those cases in which, for example, not already since the second reference intake time period but the until the next reference intake time remaining period is displayed.
• the second reference administration time also represents a point in time in the collection regime at which a portion of medication should ideally be taken. The difference is only insofar as a portion of medication was taken in the case of the second reference intake and not in the case of the first referral. In this respect, the explanation given above for reference intake times also applies here.
• the second visualization means represents the second time span that has elapsed since the most recent second referral time of a portion of medication when properly taken.
• the user can receive additional information about the current status of the intake of medication portions with proper compliance with the revenue rules.
• the period of time since the most recent second referral date has elapsed the user can prepare for the next drug intake.
• the second visualization means is preferably started by a first withdrawal of a drug portion from the donor in a take cycle.
• the second reference administration time and thus also the first reference administration time are therefore preferably defined and defined for a current intake cycle.
• a taking cycle is determined, for example, by the totality of all income processes during a disease.
• the intake cycle is also characterized by a first withdrawal and in the case of contraception through a take and a break phase before a new intake phase begins.
• the user can redefine the reference intake times in a new cycle. This is advantageous if the originally selected reference administration time has proven to be impractical for the user and the user desires a changed reference administration time.
• the first reference administration times result from the fact that no drug portion has been taken until the first reference administration time subsequent to the second reference administration time.
• the first visualization means is thus started by reaching the first reference intake time, i. if no portion of medication has been taken until this first reference administration time.
• the second period of time since the second reference administration time includes the first time interval which has elapsed since the first reference administration time.
• the first and the second visualization means indicate the period since the most recent second reference taking time, i. since a reference intake time, which is characterized in that it lies within a predetermined administration time interval in which the drug portion has been taken and therefore a proper intake has taken place.
• a new second reference intake time is generated.
• the second visualization means has indicated the second time span since the (previous) second reference administration time (because the nominal period for taking the medicine portion has not yet elapsed)
• the second time period display is cleared and a new one is displayed second time period, which represents the time difference between the current time and the new second reference intake time.
• This second period of time is negative in the latter case, ie the second time interval between the current time and the not yet reached new second reference intake time is initially displayed.
• the second time period in this case may also be in the form of the period not yet elapsed until the next reference date. Ingestion time are displayed.
• the not yet expired time period is preferably displayed in two scale parts: a first scale part, which reaches the remaining period until the previous reference intake time, and a second scale part, the regular second period of time.
• a first scale part which reaches the remaining period until the previous reference intake time
• a second scale part the regular second period of time.
• the first visualization means also indicates a first time period since this (newly generated) first reference administration time Deleting the indication of the first time period by the removal of a portion of medication, and displaying a new second time period representing the time difference between the current time and the new second reference intake time. Since the drug portion in this case was not taken until after the next reference intake time had already passed without taking a drug portion, the second visualization means will indicate an already elapsed second time period since the new second reference intake time.
• the second reference administration time in cases in which the previous second reference administration time has been considerably exceeded is set to a new second reference administration time, which is shifted by two intake periods between each two consecutive reference administration times and not only one, ie in this case the drug intake will be suspended once.
• the display is only offset by one intake period when a portion of medication is withdrawn, so that the user is prompted to take another portion of the medication in order to resume the proper intake rhythm.
• a new second reference administration time is only generated in the case of premature withdrawal of a medication portion if the medication portion is at the earliest within the administration time interval. If the withdrawal time is still before the beginning of the administration time interval, the withdrawal is not considered as a drug intake, so that it remains in the previous display of the second period of time, because in this case a new second reference intake time is not generated. On the other hand, if a drug is present within the administration time interval When the second reference administration time is reached, a new second reference administration time is generated. In this case, a new negative second time period is initially displayed, ie the time interval between the current time and the later new second reference intake time. A new second reference administration time is also generated, as explained above, if the drug is taken only after the expiration of the administration time interval.
• the first visualization means are arranged in at least one first display area and the second visualization means are arranged in at least one second display area of the display.
• the at least one first display area and the at least one second display area are adjacent to one another.
• the first visualization means is formed by at least one first display element.
• first display elements are provided and the first display elements are switched on successively as the time progresses.
• the first display elements represent the timing graphically and not in the form of a numeric display.
• the first display elements can also display a digital display.
• the numeric display may indicate the number of drug portions still to be taken.
• the second visualization means is formed by at least one second display element.
• the second display elements are provided and the second display elements are switched on successively as time progresses or are switched off successively.
• the second display elements preferably represent the timing graphically and not in the form of a numeric display. In the case of the successive shutdown of the display elements as time progresses, all are initially Display elements or at least the display elements for periods of time that remain until the next reference intake time, displayed and then turned off as time progresses.
• the graphic representations provide a quick, simple and error-free recognizability of the first or the second time span.
• each of the at least one first and / or each of the at least one second display element corresponds in the case of the graphic representation to equal-sized time segments, for example 1 hour.
• a particularly advantageous design of the display of the first and second time periods is given by the fact that each of the at least one first display element forms a segment on at least one first circle and / or that each of the at least one second display element forms a segment on at least one second circle ,
• a clock representing an analogue time representation the time progress of the respective time periods can be recognized at first glance.
• the easy and quick recognizability is further improved by the fact that the at least one first circle for the at least one first display element and the at least one second circle for the at least one second display element are concentric to one another.
• the second visualization means comprises display elements on an outer circle and the first visualization means display elements on one or more inner circles, the display elements forming the circles will gradually fill the circles from outside to inside as time progresses.
• the second display elements may also be arranged together with first display elements on a first outer circle and further second display elements on further inner circles arranged further inside.
• each of the first and second circles each symbolize a period of 1 day. If the circles are composed by circle segments, each of the circle segments can symbolize 1 hour so that there are 24 circle segments each on a circle.
• the display elements may be substantially rectangular or take any other shape. For example, they may be circular or star-shaped.
• display representations instead of circular segments other display representations are used, for example stepwise or continuously swelling bars or hands on a scale, or even a completely different representation that reveals the progress of the time at a glance.
• a numeric display shows the time progress numerically by a time.
• the first display elements of the first visualization means and the second display elements of the second visualization means each symbolize periods of time that have been covered or are still covered.
• these first and second display elements may be arranged in the form of circle segments on one or more circles.
• circle segments can be used in this case, which are shown in a planar manner
• circle segments which only represent frames.
• the second display elements of the second visualization means are reproduced in the form of a framing for the two-dimensional representations of the first display elements of the first visualization means.
• the second display elements of the second visualization means are in this case on the same circle as the first display elements of the first visualization means.
• first display elements of the first visualization means can be provided, which are located on further circles on which there are no second display elements of the second visualization means.
• first display elements and the second display elements together form an outer circle and the other first display elements form a further inner circle.
• second display elements on the inwardly offset circle can be at least partially possible.
• further circles, for example even further inside, are also conceivable for display elements.
• the second display elements of the second visualization means display the time progress since the second reference intake time by successively switching off second display elements initially displayed. That is to say, when a portion of medication is withdrawn and thus when a second reference administration time is determined, all second display elements are initially displayed, ie the display elements are displayed for periods until the next (not yet reached) second reference administration time.
• the first display elements of the first visualization means can be successively displayed with the increasing timeout as in the case described above.
• the second visualization means immediately after a withdrawal of a drug portion immediately the remaining time until the next reference intake time, while the first visualization means in a subsequent timeout immediately indicates the time already incurred.
• the first visualization means may comprise a first zone and a second zone spatially delimited by the first zone, the second zone serving to represent an exceeding of a predetermined third time. If the exceeding of the first reference administration time takes place by a predetermined third period of time without the user taking a portion of medication, serious consequences can result from the incorrect intake. This is then signaled by a display, for example, held in another (signal) color, of first display elements in the second zone, which is spatially delimited by the first zone.
• the display elements in the first and the second zone can each represent a period of one day, so that a total of exceeding the first reference intake time of 2 days can be displayed. In principle, of course, exceeding the first reference intake time by a shorter or longer period is possible.
• an additional indication of the number of drug portions in the dispenser is provided.
• the display may be, for example, a digital numeric display. This provides the user with additional security for taking the medicine portions, thus ensuring that the user can always ensure that at least one portion of medication is always available. By way of example, the user can thus plan sufficiently for an upcoming journey.
• an additional indication of the number of medicament portions already taken in a given intake cycle is provided.
• This information can also be displayed by a numeric display.
• the user has to decide when to start an interruption phase after a period of ingestion in which she has taken 24 contraceptive portions (compulsory intake phase). This is important in view of the restrictions on the decision to initiate the interruption phase, since the interruption phase must not be initiated before the start of the compulsory intake phase and must be initiated at the latest after a total intake of, for example, 120 contraceptive portions.
• an indicator for a revenue interruption is additionally provided. This can be realized by a symbol suitable for this purpose.
• the interruption period usually takes 4 days in a flexible regime.
• a revenue phase is then initiated again in a new revenue cycle. To do this, the user removes a first portion of medication in this new intake cycle, triggers the second visualization agent and thus determines the new reference intake times.
• control for the display may also include a logic, after which an initiation of the interruption phase is excluded if not 24 drug portions have been taken in the current intake cycle (mandatory intake phase). This can then be indicated, for example, by the fact that the symbol indicating the interruption of receipt does not appear or is crossed out.
• a visual, audible and / or haptic perceptible warning signal can be displayed.
• the display device automatically initiates the interruption phase when the last dose of a portion of medication is a minimum of a period of time ago. For example, it can be provided that the interruption phase is initiated automatically when the second reference intake time 72 hours ago. By switching over to the interruption phase, the display can show in this case that the interruption phase has been going on for 48 hours.
• Such an automatic transition is readily possible when the user has already reached the flexible intake phase. But even if the user is still in the mandatory phase, this automatic transition can take place in a possible embodiment of the invention. A secure contraception is not given in the latter case. With the automatic transition to the interruption phase but again a proper revenue regime is sought.
• the revenue interrupt display includes an indication of the number of days of revenue interruption.
• This display can again be in the form of a digital numeric display.
• the first or the second visualization means indicate the time elapsed between two reference intake times during the intake interruption.
• These reference intake times are those times which, like the first reference intake time and the second reference administration time, are calculated from the time of the first withdrawal of a portion of medication in a revenue cycle and which are in the period of the revenue interruption.
• the time progress can also be tracked during a revenue break, so that the user in this phase continuously has a good overview of the status of the interruption phase.
• the user is informed that she has to take two medicament portions when the second reference administration time is longer than 2 intake periods, but preferably not longer than 3 intake periods, ie the user / In this case, the user withdraws all (two) medicament portions heretofore missed.
• the display of the timeout is deleted (by the first visualization means) in a withdrawal of only a portion of medication only to the extent of the period individual portion of medication corresponds to a daily intake of a portion of medication so in the amount of the period corresponding to one day.
• the medicines are contraceptives, which are taken in a flexible revenue regime, such a procedure can in principle be provided both for the case in which the user is in the obligatory phase or in the flexible phase.
• a timeout of up to 48 hours i.e., a period of up to 72 hours since the second reference taking time
• the display will automatically transition into the interruption phase.
• additional contraception must also be used since effective contraception no longer exists under these conditions. In such an event can be provided that the user is alarmed with an optical and / or audible and / or haptic alarm signal and additionally preferably optically the hint is given to apply in addition to further taking the drug portions an additional contraceptive.
• the first day on which additional contraceptive measures become necessary is a day of ingestion following the abovementioned 7-day period with irregular ingestion within less than 7 days with uninterrupted intake of medicated portions.
• a misuse period of more than 7 days, without this misuse period would be interrupted by a period of 7 days of uninterrupted intake of medicine portions.
• a period of at least 7 days should be followed by uninterrupted ingestion of medication to maintain the contraceptive effect.
• the above rules are independent of whether tablets are not taken on days when tablets are to be taken in accordance with the intended intake regimen (intake phase) or whether these days are in an interruption phase, ie. that on these days according to the revenue regimen no tablets are to be taken. In other words, days on which no tablets are to be taken according to the revenue regimen are treated as days with ingestion.
• the display device is preferably designed such that it indicates on the day under the above-mentioned conditions whether additional contraceptive measures are required. For this, a warning symbol due to lack of contraception can automatically be added. For example, an exclamation mark ("!) will appear on the display As explained above, this warning symbol will appear under the following conditions: a) There is a misappropriation period which is characterized
• the first day on which the warning symbol appears is the 8th day of the misappropriation period
• the display device is a digital display device.
• the display device may be an LCD display device.
• an OLED display can be provided.
• any other technologies can be used.
• the display device may also contain other display elements for other functions, for example a symbol for a low battery state of charge, a symbol for the indication of whether an acoustic warning signal is switched on or off, a symbol for indicating to the user, the operating instructions
• a symbol indicating that the digital numeric display indicates the number of medicine portions still in the dispenser, a symbol indicating that medication portions are low, is a symbol indicating that the digital digits are indicates the number of drug portions already taken in a revenue cycle, a symbol to confirm that a portion of medication has been taken, and a symbol indicating that an interruption phase may not be initiated by a corresponding attempt by the user.
• These symbols can each be displayed as a continuous display or in the form of a flashing display. The symbols are preferably displayed alternatively or partly simultaneously on the display device.
• the display device may be designed so that further optically, acoustically and / or haptically perceptible warning signals can be emitted.
• the display device comprises an electronic control for the display. This may be a programmed or programmable microprocessor circuit in a conventional manner.
• the display device is preferably operated by controls on the dispenser. These may be, in particular, buttons or other sensors.
• controls on the dispenser may be, in particular, buttons or other sensors.
• a menu button and a confirmation button can be provided.
• the menu button is used to select specific display or selection modes.
• the confirmation button is used to make a possible selection in a certain mode.
• the dispenser may include, in addition to the display, other visual display elements such as LEDs as well as additional acoustic alarms (speakers) and / or mechanical alarms (vibrators).
• other visual display elements such as LEDs as well as additional acoustic alarms (speakers) and / or mechanical alarms (vibrators).
• All display elements of the display device can either be constantly displayed or displayed flashing.
• the display elements can also be displayed either in a neutral (as high contrast) color, for example in black color, or all or even individual display elements can be executed in a signal color, for example in red.
• escalation levels may be provided, for example, instead of a black representation, a colored, for example red, representation.
• a flashing display can be selected instead of a continuous display.
• the display device is combined with a dispenser for the medicament portions.
• the dispenser the display device in the case the withdrawal of a portion of medication triggers without an interposition of the user, ie a withdrawal of a portion of medication leads directly to a consideration of a withdrawal of a portion of medication, without the user must make this a separate input for the removal.
• This triggering can take place mechanically, electromechanically, electronically or in another way.
• the dispenser may allow a delivery of drug portions based on mechanical or electromechanical force transmission from actuation means to an output unit, and it may be provided that the mechanical or electromechanical force transmission acts directly on the display means upon withdrawal of a drug dose, for example by means of a switch that thus the removal is registered in the display device without additional manipulations of the user. Due to the automatic triggering of an incorrect operation is largely prevented by the fact that the user can not record the removal in the display device incorrectly.
• the medicament portions may, as in conventional donors in the form of tablets, pills, dragees o.a. be prepared.
• the portions can basically be packaged in the form of blisters.
• packaging of the drug portions in cartridges, i. in a columnar arrangement.
• the drug portions may in this case be dispensed through an axial opening in the cartridge.
• Fig. 1 shows a dispenser with a display device according to the invention in a front view
• Fig. 2 shows the dispenser in a rear view
• Fig. 3 shows the display of the display device according to the invention in a first embodiment according to the invention in plan view
• Fig. 4 shows the display of the display device according to the invention in the first embodiment according to the invention before the first insertion of a cartridge and then in different display modes;
• Fig. 5 shows the display of the display device according to the invention in the first embodiment according to the invention after the first removal of a tablet in a taking cycle
• 6 shows the display of the display device according to the invention in the first embodiment according to the invention before and after removal of a tablet taking place before the second reference administration time has expired;
• FIG. 7 shows the display of the display device according to the invention in the first embodiment according to the invention before and after a removal of a tablet taking place before the beginning of the administration time interval
• Fig. 8a shows the display of the display device according to the invention in the first embodiment of the invention after exceeding the first reference intake time and in addition with switching (on / off) of the audible warning function;
• 8b, 8c show the display of the display device according to the invention in the first embodiment according to the invention after exceeding the first reference intake time at different first time periods;
• Fig. 9 shows the display of the display device according to the invention in the first embodiment of the invention in the transition to the interruption phase
• Fig. 10 shows the display of the display device according to the invention in the first embodiment of the invention during the interruption phase
• Fig. 11a shows the display of a display device according to the invention in the first embodiment according to the invention before and after a removal of two tablets without taking into account the second tablet for ingestion after briefly exceeding the first reference administration time;
• Fig. 11b shows the display of the display device according to the invention in the first embodiment according to the invention before and after a removal of two tablets without taking into account the second tablet for ingestion after prolonged exceeding the first reference administration time;
• Fig. 12a shows the display of the display device according to the invention in the first embodiment according to the invention before and after removal of two tablets, taking into account also the second tablet for ingestion after briefly exceeding the first reference administration time;
• Fig. 12b shows the display of the display device according to the invention in the first embodiment according to the invention before and after a removal of two tablets taking into account the second tablet for use after prolonged exceeding the first reference administration time; 13 shows the display of the display device according to the invention in the first embodiment according to the invention during the automatic transition from the flexible phase into the interruption phase;
• Fig. 14 shows the display of the display device according to the invention in the first embodiment of the invention in the automatic transition from the mandatory phase to the interruption phase;
• Fig. 15 shows the display of the display device according to the invention in the first embodiment of the invention in a low battery state of charge
• FIG. 16 shows the display of the display device according to the invention in a second embodiment according to the invention with alternative symbol representations
• Fig. 17 shows the display of the display device according to the invention in the second embodiment according to the invention since the second reference administration time at different stages of the time progress;
• Fig. 18 shows the display of the display device according to the invention in the second embodiment of the present invention since the first reference taking time at various stages of time progress;
• Fig. 19 shows the display of the display device according to the invention in the second embodiment according to the invention when the time lapse exceeds more than one intake period at different stages of the time progress;
• Fig. 20 shows the display of the display device according to the invention in the second embodiment according to the invention before and after the removal of a tablet;
• Fig. 21 shows the display of the display device according to the invention in the second embodiment according to the invention after the initiation of an interruption phase
• Fig. 1 shows a dispenser Sp for drugs in a view from the front. In the lower area of the dispenser, the lower part of a medicament cartridge Ka inserted axially into the dispenser from below is visible. The medicine portions are dispensed downwards (arrow). For this purpose, the cartridge on the bottom of an ejection mechanism which is actuated by lateral push-button Dt.
• a display device with a display 1 and operating buttons Me, Ok are attached to the front of the dispenser Sp.
• the menu key Me is used to select a particular display or selection mode on the display
• the confirm key Ok is used to confirm selection of a function indicated by the display.
• Fig. 2 shows the dispenser Sp in a rear view.
• the housing of the dispenser Sp is centrally provided on the back axially with a window Fe through which a part of the present in the cartridge tablets Ta is visible.
• a mark Mk is attached in the form of a line indicating the level at which there are still 7 tablets in the cartridge.
• the user also has direct visual control of the level of the dispenser with tablets.
• FIG. 3 shows the display 1 of a display device according to the invention with a magnified view of a display element 20 located on a circle.
• This illustration serves merely to illustrate all possible display elements and symbols on the display. Usually not all elements and symbols will be visible at the same time but only displayed in accordance with the display situation.
• the display is preferably an LCD display, which particularly preferably has illumination or at least optionally illumination.
• the display elements and symbols shown here do not need to be continuously displayed:
• the display device can be automatically transferred to a rest position in which the display elements and symbols are not visible.
• the display device for example, go back to an active state by pressing a button.
• most of the display elements and icons of display 1 are black in color to provide a good contrast to the background.
• some display elements and symbols may be differently colored.
• the display 1 is equipped with sectoral display elements 20, 30, 40, which are each located on a circle. These circles are concentric with each other.
• the second display elements 20 on the outer circle taken together represent the second visualization means. 24 such sectoral second display elements form a circle.
• the 24 second display elements are each intended to represent 1 hour, so that all 24 second display elements are displayed for 24 hours, i. 1 day, symbolize.
• display frames 210 are provided which are also visible when the display surfaces 220 of the second display elements arranged in this frame are not shown.
• the first display elements 30 and 40, taken together, constitute the first visualization means. While the first display elements 30 are held in black, the first display elements 40 may be shown in red.
• Each 24 such sectoral second display elements form a circle, wherein two circles are provided by second display elements.
• the first display elements 30 in black color are arranged in a first zone (middle annulus) and the first display elements 40 in red color in a second zone (inner annulus).
• the second zone serves to represent an exceeding of a predetermined third time period, wherein the third time period is represented by the totality of all the first display elements 30 on the entire central annulus.
• a three-digit digital display 50 located in the center of the display 1 is a three-digit digital display 50, which has different meanings depending on the mode.
• a symbol 52 for a cartridge is shown to the left of the digital display.
• the number of tablets remaining in the cartridge is displayed.
• This symbol can be displayed both in the continuous display position and flashing, the latter when there are no more tablets in the cartridge.
• a symbol 54 for a daily calendar is shown to the right of the digital display. When this symbol and the digital display are displayed simultaneously, the latter displays the number of days covered in the current intake cycle.
• a symbol 60 for a revenue interruption If this symbol appears together with the digital display, the digital display shows the days already in the interruption phase.
• a warning and attention symbol 65 which is displayed in different situations and that in a steady display position or in the flashing position. This symbol can be shown in the illustration shown here with a strikeout or without a strikeout. In a crossed-out illustration, this symbol is displayed along with the interruption phase symbol, indicating that an interruption phase may not (yet) be initiated.
• a confirmation icon 70 which appears, for example, when a tablet is confirmed to be ingested.
• an indication icon 80 indicating that an audible warning indicator is activated (without strikethrough) or disabled (with strikethrough, as shown in the figure).
• an alarm icon 82 prompting the user to consult the manual and, on the left, a siren icon 84 indicating a low battery condition. These two symbols are not in black, but are preferably painted in red or some other signal color to accentuate the warning nature of these indicators.
• the alarm icon 82 can be displayed not only in a continuous display but also as a flashing display, the latter when the user tries to initiate the interruption phase during the mandatory intake phase.
• Fig. 4 shows the display 1 of the display device according to the invention, first before the first insertion of a cartridge filled with tablets into the dispenser and then after insertion.
• the dispenser Before a cartridge is inserted into a dispenser for the first time, there is no display element and no symbol on the display 1 (left illustration), because in this case the dispenser is designed so that the battery in the dispenser with the display device still remains not connected. Subsequently, the cartridge Ka is inserted into the dispenser (step 1). This activates the dispenser and the display device. The start display appears on display 1 (default screen). Initially, only the audible indicator 80 and, by way of example, a digital number representation by the digital display 50, two horizontal bars are displayed on the display. This representation is the standard representation of the display.
• the first display mode will appear in a first level, showing the days already elapsed in a collection cycle:
• the calendar symbol 54 is displayed. This is to symbolize at this stage before the first removal of a tablet from the donor that still no value for the number of days covered in a revenue cycle can be displayed.
• the second display mode appears in a second level, in which the number of tablets remaining in the cartridge is displayed:
• the cartridge symbol 52 appears 30 tablets in the inserted cartridge.
• the cartridge symbol is displayed in a continuous display position - not flashing. For example, when the number of tablets falls below 6 (preset value), the cartridge icon blinks.
• the cartridge icon appears in the default screen, which should indicate that only a few tablets are still present in the cartridge.
• the third display mode in which the acoustic alarm mode can be switched on or off appears in a third level: in addition to the notification of the acoustic warning message 80, the warning / warning symbol 65 is shown flashing , shown.
• the fourth display mode in which the interruption phase is initiated or displayed appears: At the bottom center of the display 1, the symbol 60 for the stoppage is displayed. In the Center is the digital display 50, which in the present case, instead of a single-digit number for the number of days interruption shows a single horizontal bar. In the upper right corner are the alarm symbol 82 and lower left the warning / warning symbol 65 with crossed out OK display, because in the present phase the user is still at the beginning of the intake phase and thus can not yet initiate the interruption phase.
• the display device After pressing the menu key Me again (step 6), the display device returns to the standard display mode. Likewise, if the menu button is not pressed for a period of 3 seconds, the display device would automatically return from one of the first to fourth display modes to the default setting mode.
• the user can now remove a tablet Ta from the dispenser (step 7). By removing the tablet, the revenue regimen is started.
• the second visualization means is initially started:
• the display 1 of the display device is shown after the first tablet has been removed. For example, if the tablet has been removed at 7:00, this time represents the second reference ingestion time.
• the display shows a circle of 24 display frames 210 of the second visualization means, each symbolizing 1 hour. As can be seen in the lower left illustration, immediately after the removal of the first tablet, none of the display frames 210 is filled with a display surface. Further, the display device displays the confirmation icon 70 and the audible warning indicator 80. The confirmation icon indicates that a tablet has been successfully withdrawn for ingestion.
• step 2 After pressing once (step 2), the first display mode will appear, indicating that 1 day has elapsed in the current intake cycle. After pressing twice (step 3), the second display mode appears, indicating that in the cartouche see still 29 tablets are. After pressing it three times (step 4), the third display mode appears, in which the audible alarm mode can be switched on or off. After four operations (step 5), the fourth display mode in which the interruption phase is initiated or displayed appears. However, this is not possible in the current phase, since the user is still in the mandatory intake phase after taking only 1 tablet (warning / instruction symbol 65 crossed out).
• the display 1 After pressing the menu key Me again (step 6), the display 1 returns to the standard display mode.
• the middle lower panel indicates that approximately one hour has elapsed since removal (first display panel 210 of the second visualization means filled with a display area). In the lower right-hand illustration it is indicated that about 2 hours have passed since the removal (two display frames 210 filled with display areas).
• the tablet does not necessarily have to be taken at the time of referral. It is sufficient if it is taken within a take time interval. In the present case, for example, it may be taken within a time interval of 12 hours before to 2 hours after the reference administration time.
• the tablet Ta is taken in the present case within the 12-hour administration time interval before the reference administration time (step 7). Therefore, the confirmation icon 70 appears in the subsequently appearing display 1.
• the remaining period until the next reference taking time is represented in terms of "negative time” by first filling the display frames 210 with display areas that are on from the time of removal and intake (-11 hours) until the current second reference intake point is reached, after which the display frames are filled with display areas in the normal manner starting from the first display element above.
• the situation is different if the tablet Ta is already taken out of the donor prematurely, ie before the beginning of the administration time interval. This is shown by way of example in FIG. 7. In this case, the second time period since the last second reference intake time only 11 hours. Thus, a subsequent removal of a tablet Ta (step 7) is not posted as an effective revenue (no display of the confirmation icon, no change in the display in the second visualization means).
• Fig. 8a the display 1 of the display device is shown after exceeding the first reference intake time (bottom left).
• the fully displayed second display elements 20 of the second visualization means are shown on the outer circle, but also 5 first display elements 30, which symbolize that the user still after expiration of the first reference intake time by 5 hours crossing first time period has not taken a tablet.
• the user By repeatedly pressing the menu button Me, the user successively enters the first display mode, in which it is indicated that the user is on the 28th day of the intake cycle (step 2), in the second display mode, in which it is still 18 Tablets are in the cartridge (step 3) as well as in the third display mode, where it is possible to turn the audible indicator 80 on or off (step 4).
• the reminder is turned on, because the note icon 80 is not crossed out.
• the confirm button Ok the state "audible warning off” is selected (step 10), this selection can be canceled again by pressing it again, and you can switch between these two states as often as you like.
• the warning / warning icon 65 is shown in the blinking state. This means that the user can switch to the interruption phase in this intake phase (flexible intake phase).
• FIGS. 8b and 8c Further representations for exceeding the first reference administration time are shown in FIGS. 8b and 8c: In FIG. 8b, an exceeding by 18 hours (second display elements 20 are complete and 18 first display elements 30 present) and in FIG. 8c an exceeding by 29 Hours (second display elements 20 complete, first display elements 30 complete and 5 first display elements 40 present).
• the display in Figure 8b also indicates that the user is on the 38th day of the intake cycle, i. in the flexible intake phase.
• the user is also advised to consult the operating manual because of the considerable exceeding of the first reference administration time by 29 hours (alarm symbol 82).
• Fig. 9 the transition to the interruption phase is shown: In the lower left display of the display 1 it is shown that the user has exceeded the first reference intake time by 5 hours. This can be seen from the fact that all the first display elements 20 of the first visualization means and 5 second display elements 30 of the second visualization means are displayed.
• the display device is switched to the fourth display mode by the first to third display modes (steps 2, 3, 4, 5). In this display mode, the revenue interrupt icon 60, the alert / alert icon 65, and the digital display 50 are shown.
• the warning / warning symbol indicates that initiation of the interruption phase is possible.
• the fourth display mode is selected by pressing the menu key Me (steps 2, 3, 4, 5).
• the presentation appears, in which the user has the choice to initiate the interruption phase. This is indicated by the symbol 60 for the revenue interruption.
• the warning / indication icon 65 confirms that the start of the interruption phase is possible.
• the display elements 20 of the second visualization means indicate that 5 hours have elapsed on this first day. It is the time elapsed since the first reference administration time (see time display of the second visualization means on the display according to the large display of the display).
• the confirmation button Ok step 9 the system switches to the interruption phase.
• the digital display 50 now indicates that the user is on the first day of the interruption phase.
• the display 1 indicates with the digital display 50 as well as with the second display elements 20 of the second visualization means the respective time period covered.
• the display switches to the start display. If a new tablet is removed in this situation, then the procedure results, which has also already been described with reference to FIGS. 4, 5.
• the alarm symbol 82 appears in the permanent display position (last representation in the row of illustrations in FIG. 10). This will ask the user to consult the user manual.
• a beep may sound to remind the user of the start of the new intake phase, for example, for a few seconds, with the beep repeated several times at a particular rhythm, say 15 minutes apart.
• FIG. 11a left display: second display elements 20 (outer ring) complete and 7 first display elements 30 (inner ring) present
• a first tablet Ta is taken (step 7)
• the device switches to a display indicating that 7 hours have elapsed since the last second reference intake time (Figure 11a: middle view: 7 second display elements 20 fully present).
• the removal is confirmed in this case with the confirmation icon 70.
• FIG. 11 a right-hand representation: no further change in the display elements 20, no indication of the confirmation symbol).
• the device switches to a display, according to which 15 hours have elapsed since the last second reference administration time (FIG. 12a: middle illustration: 15 second display elements 20 completely present).
• the removal is confirmed with the confirmation icon 70.
• a tablet Ta is removed again, it is taken into account as an additional dose because this second withdrawal is within the time interval of the next reference administration time (time interval begins at reference administration time minus 9 hours). This revenue is again confirmed with the confirmation icon 70.
• the display 1 now displays a new negative second period of time: FIG. 12a, right-hand illustration shows that the second display elements 20 start counting, starting from a display element 20 "reference intake time minus 9 hours".
• FIG. 12b right-hand illustration, shows that the second display elements start counting, starting from a display element 20 "reference intake time minus 6 hours".
• Fig. 13 is shown how the device automatically changes from the flexible phase to the interruption phase:
• the device automatically switches to the display 1 to the right (smaller), after which the user is now in the interruption phase.
• This can be seen from the symbol for the revenue interruption 60 as well as the fact that the digital display 50 only appears single-digit.
• the digital display indicates that the user is already on the third day of the interruption. This results from the longer time delay in the removal of tablets from now over 48 hours.
• the further illustrations in FIG. 13 show the situations in each case on the fourth interruption day (5 hours after the reference administration time), immediately after the end of the interruption period and after a further passage of time, without the user having taken a tablet.
• Fig. 14 shows such a transition to the interruption phase even in the case where the user has failed to take the tablets in the mandatory intake phase. Since the contraception in this situation is not certain anyway because of the missed tablet income, the display device switches to the interruption phase in order to guide the user back into the intake phase. The display in this case does not differ from that which appears when switching from the flexible phase to the interruption phase.
• the display 1 is displayed at a low battery state of charge.
• the low-battery state warning icon 84 is shown.
• the ad indicates that the user is in a receipt phase (not an interruption phase icon).
• the state of charge of the battery is always such that the intake cycle can still be carried to the end. Therefore, the user will phase can still lead to the end of the interruption phase (middle illustration).
• the display device does not change to the standard representation but switches off the display (right-hand representation).
• FIG. 16 shows a display of a display device according to the invention in a second embodiment.
• first sectorial display elements 30, 40 and the second sectoral display elements 20 on three circles, only sectorial first display elements lying on two circles can be seen here because both types of display elements do not appear simultaneously in this embodiment.
• the second display elements of the first type 30 are kept black, the second display elements of the second type 40 are colored red to signal the user a significant timeout.
• the shapes of the stop-taking icon 60, the warning and notification icon 65, the day calendar icon 54, and the warning indication enable / disable icon 80 are different from the corresponding symbols of the first embodiment (see FIG 3).
• a confirmation icon is not provided.
• the arrangement of the symbols differs slightly from that of the first embodiment.
• FIG. 17 shows the start presentation on the display 1 (default screen) at various stages of the time progress:
• the second sectoral display elements 20 which indicate the time progress since the second reference taking time (symbolized by the external large triangle 90) each for 1 hour.
• These display elements each consist of a substantially rectangular frame.
• all display elements are turned on to signal a user that the entire period is still available until the next reference intake time.
• Fig. 17 (a) 1 hour has passed since the second reference taking time. Since the last tablet was taken shortly before taking this presentation, the display already shows only 23 display elements to signal that only 23 hours remain until the next reference intake time.
• 6 hours have already elapsed, so that also 6 display elements are turned off.
• FIGs. 17 (c), (d) and (e) show respective representations 13 hours, 2 hours and 1 hour, respectively, before the next reference taking time. If the next tablet is taken before the second reference intake point 90 is reached, a prolonged remaining time period must be displayed until the next second reference intake point for taking the subsequent tablet. This can be realized, for example, by displaying all the second display elements 20 of the second visualization means after removal of the tablet, and moreover display elements which, for example, lie on a circle offset inwards relative to the outer circle and correspond to the remaining period exceeding 24 hours (not shown). For example, if the next tablet is taken 2 hours before the second reference administration time (corresponding to Fig.
• FIG. 18 again shows the start-up display on the display 1 (default screen) at various stages of the time progression following FIG. 17, but in this case after the next reference intake time 90 has elapsed without a tablet being taken.
• the most recent reference intake time is a first reference intake time.
• the second display elements are deleted.
• first display elements 30 appear which indicate the timeout.
• Fig. 18 (a) it is shown that 1 hour has passed since the first reference taking time.
• Fig. 18 (b) - (e) further time advances are shown, namely, 7 hours, 12 hours, 19 hours, and 23 hours, respectively, from the first reference administration time.
• the numeric display 50 indicates that 1 tablet has not yet been taken.
• the modified warning symbol 80 for the activation or deactivation of the warning indication indicates that the intake time has been exceeded.
• Fig. 19 indicates the further time progress after more than 24 hours have elapsed since the first reference administration time.
• This is now in addition to the first display elements 30 on the outer circle, a further first display element 40 is displayed on a further inner circle.
• This further display element is preferably kept in red to warn the user of a further timeout.
• the digital display 50 indicates that now already 2 tablets have not been taken.
• FIG. 20 shows the display 1 which results before (FIG. 20 (a)) or after (FIG. 20 (b)) the removal of a single tablet.
• Fig. 20 (a) corresponds to the illustration in Fig. 19 (c).
• the indicator indicated that 2 tablets had not been taken.
• the display will now show that one more tablet has to be taken. This can be seen on the digital display 50 as well as on the deletion of the first display elements 40 and the partial deletion of the first display elements 30. Now, another 1 tablet would have to be taken in order to meet the required rhythm again. If this additional tablet is taken, the first display elements 30 are also deleted, and (in the present case) 4 second display elements are shown (not shown) indicating the time period until the next reference administration time.
• contraceptive pills are not taken regularly, contraception can no longer be guaranteed under certain conditions. In this case, it is necessary for the user to use additional contraceptives. This requirement can be separately and concretely displayed on the display 1 by means of a warning symbol due to missing Contraception, such as an exclamation point ("!), which will only be displayed if adequate contraception is no longer guaranteed, and should signal to the user that additional contraceptive devices must now be used. If the tablets are taken irregularly, it depends on what periods of time on the one hand regular, ie regular intake, and on the other hand, discontinued use of tablets result.In Fig.
• Fig. 22a an example of administration is shown in which the ingestion of a tablet was forgotten on the 28th and then again on the 36th day. Additional contraceptive measures are not required in this case for the following reasons (no entry in the third line): only on a single day within a period of 7 days with irregular intake (for example, from the 28th day to the 34th day) the tablet is not taken and before that day is a 7-day period (21st day to 27th day), on which the tablets were taken regularly. Furthermore, the day on which the tablets were not taken (28 days) is followed by another 7-day period (29 days to 35 days) in which the tablets were taken regularly. The misappropriation period is in this case only 1 day (28th day).
• additional contraceptive measures are required: Within a period of 7 days with irregular ingestion, calculated from the first day on which a tablet has not been taken after at least 7 days of uninterrupted ingestion (28th day), 2 Days tablets were not taken, namely on the 28th day and on the 34th day. The last day of this 7-day period is not followed by at least 7 days of uninterrupted pills, as pills are not taken on the 35th, 36th and 37th days. The misappropriation period is 10 days, since it extends from the 28th day to the 37th day. The first day on which additional contraceptive measures become necessary is the 8th day following the 7-day period with irregular ingestion from the 28th day onwards.
• Fig. 22c an example of ingestion is shown in which the tablets were not taken on the 34th, 35th, 36th and 37th day and then again on the 40th day.
• additional contraceptive measures are not required: within a missed intake period of 7 days from the first day on which a tablet has not been taken after at least 7 days of uninterrupted ingestion (34th day), are at 5 Tablets were not taken on the 34th day, the 35th day, the 36th day, the 37th day and the 40th day.
• Fig. 22d an example of ingestion is shown in which the tablets were not taken on the 34th, 35th, 36th and 37th day and then again on the 41st day.
• additional contraceptive measures are required: Within a period of 7 days with irregular ingestion, calculated from a first day on which one tablet is at least 7 months old Days during continuous use have not been taken (34th day), on 4 days tablets were not taken, namely on the 34th day, on the 35th day, on the 36th day and on the 37th day. The last day of this 7-day period (40th day) with irregular ingestion is not followed by a period of at least 7 days in which uninterrupted pills are taken because on the 41st day one tablet is not taken.
• the misappropriation period lasts 8 days.
• the first day on which additional contraceptive measures become necessary is the 8th day following the 7-day period with irregular intake. This is the 41st day because the 7-day period with irregular intake ends on the 40th day.
• the requirement for additional contraceptive measures then continues until a period of at least 7 days has elapsed during continuous uninterrupted use.
• the period in which additional contraceptive measures are required lasts until the 48th day, as a 7-day uninterrupted intake is only reached on the 48th day. Therefore, the warning symbol is activated due to lack of contraception from the 41st day to the 48th day.

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• 2010
  • 2010-07-27 WO PCT/EP2010/004572 patent/WO2011012282A2/de active Application Filing
  • 2010-07-27 AU AU2010278275A patent/AU2010278275B2/en not_active Ceased
  • 2010-07-27 EP EP10740531A patent/EP2460109A2/de not_active Withdrawn
  • 2010-07-27 MY MYPI2012000388A patent/MY161906A/en unknown
  • 2010-07-27 PE PE2012000126A patent/PE20130248A1/es not_active Application Discontinuation
  • 2010-07-27 IN IN817DEN2012 patent/IN2012DN00817A/en unknown
  • 2010-07-27 CA CA2769454A patent/CA2769454A1/en not_active Abandoned
  • 2010-07-27 EA EA201200207A patent/EA022316B1/ru not_active IP Right Cessation
  • 2010-07-27 MX MX2012001370A patent/MX2012001370A/es active IP Right Grant
  • 2010-07-27 JP JP2012522020A patent/JP5676606B2/ja not_active Expired - Fee Related
  • 2010-07-27 BR BR112012008192A patent/BR112012008192A8/pt not_active IP Right Cessation
  • 2010-07-27 KR KR1020127005166A patent/KR20120056259A/ko not_active Abandoned
  • 2010-07-27 PH PH1/2012/500190A patent/PH12012500190A1/en unknown
  • 2010-07-27 NZ NZ597869A patent/NZ597869A/en not_active IP Right Cessation
  • 2010-07-27 SG SG2012005468A patent/SG178107A1/en unknown
  • 2010-07-27 CN CN201080043780.8A patent/CN102667784B/zh not_active Expired - Fee Related
  • 2010-07-27 EP EP16197372.2A patent/EP3203399A1/de not_active Withdrawn
  • 2010-07-30 US US12/847,285 patent/US9089472B2/en not_active Expired - Fee Related
  • 2010-07-30 AR ARP100102782 patent/AR077612A1/es unknown
  • 2010-07-30 UY UY32818A patent/UY32818A/es not_active Application Discontinuation
  • 2010-07-30 TW TW099125516A patent/TWI477268B/zh not_active IP Right Cessation
• 2012
  • 2012-01-19 IL IL217628A patent/IL217628A/en not_active IP Right Cessation
  • 2012-01-27 CR CR20120049A patent/CR20120049A/es unknown
  • 2012-01-30 CU CU20120017A patent/CU23940B1/es active IP Right Grant
  • 2012-01-30 GT GT201200025A patent/GT201200025A/es unknown
  • 2012-01-30 CL CL2012000235A patent/CL2012000235A1/es unknown
• 2015
  • 2015-01-08 US US14/591,954 patent/US9795539B2/en not_active Expired - Fee Related

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