EP2367543A2 - 5-ht2a und 5-ht2b rezeptorantagonisten zur behandlung der spinalkanalstenose - Google Patents
5-ht2a und 5-ht2b rezeptorantagonisten zur behandlung der spinalkanalstenoseInfo
- Publication number
- EP2367543A2 EP2367543A2 EP09795786A EP09795786A EP2367543A2 EP 2367543 A2 EP2367543 A2 EP 2367543A2 EP 09795786 A EP09795786 A EP 09795786A EP 09795786 A EP09795786 A EP 09795786A EP 2367543 A2 EP2367543 A2 EP 2367543A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- patients
- group
- stenosis
- spinal
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
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- A—HUMAN NECESSITIES
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Definitions
- this serves for the prophylactic treatment of patients with spinal canal stenosis and the symptoms caused thereby in these patients for the prevention of the chronification of the symptoms complex
- NSAIDs examples include sasapyrins, sodium salicylaf, aspirin, aspirin dialuminate, diflunisal, indomethacin, suprofen, ufenamate, dimethylisopropylazulen, bufexamac, felbinac, diclofenac, tolmetinin, clinoril, fenbufen, nabumetone, proglumetacin, indomethacin-farnesyl, acemetacin, proglumetacin maleate, amfenac sodium, mofezolac, etodolac, ibuprofen, ibuprofen-piconol, naproxen, flurbiprofen, flurbiprofenaxetil, ketoprofen, fenoprofen-calcium, tiaprofenic acid, oxaprozin, pranoprofen, loxoprofen-natrium,
- the present invention further relates to the compounds of the formula
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP09795786A EP2367543A2 (de) | 2008-12-23 | 2009-12-22 | 5-ht2a und 5-ht2b rezeptorantagonisten zur behandlung der spinalkanalstenose |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08172859 | 2008-12-23 | ||
EP09795786A EP2367543A2 (de) | 2008-12-23 | 2009-12-22 | 5-ht2a und 5-ht2b rezeptorantagonisten zur behandlung der spinalkanalstenose |
PCT/EP2009/067768 WO2010072774A2 (de) | 2008-12-23 | 2009-12-22 | Mittel zur behandlung der spinalkanalstenose |
Publications (1)
Publication Number | Publication Date |
---|---|
EP2367543A2 true EP2367543A2 (de) | 2011-09-28 |
Family
ID=40527906
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP09795786A Withdrawn EP2367543A2 (de) | 2008-12-23 | 2009-12-22 | 5-ht2a und 5-ht2b rezeptorantagonisten zur behandlung der spinalkanalstenose |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP2367543A2 (zh) |
JP (1) | JP2012513446A (zh) |
KR (1) | KR20110098965A (zh) |
CN (1) | CN102271667A (zh) |
AU (1) | AU2009331469A1 (zh) |
BR (1) | BRPI0923556A2 (zh) |
CA (1) | CA2748163A1 (zh) |
IL (1) | IL213768A0 (zh) |
MX (1) | MX2011006852A (zh) |
SG (1) | SG172315A1 (zh) |
WO (1) | WO2010072774A2 (zh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6856532B2 (ja) | 2015-01-20 | 2021-04-07 | エックスオーシー ファーマシューティカルズ インコーポレイテッドXoc Pharmaceuticals, Inc | エルゴリン化合物およびその使用 |
EP3630758A1 (en) | 2017-06-01 | 2020-04-08 | Xoc Pharmaceuticals, Inc | Ergoline derivatives for use in medicine |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2342198C (en) | 1998-09-01 | 2007-08-28 | Welfide Corporation | Therapeutic agent for spinal canal stenosis |
WO2004043491A1 (ja) | 2002-11-14 | 2004-05-27 | Ono Pharmaceutical Co., Ltd. | 脊柱管狭窄症治療剤 |
US20070167403A1 (en) | 2003-04-03 | 2007-07-19 | Yoshifumi Takenobu | Remedy for spinal canal stenosis |
DE102006013307B3 (de) | 2006-03-21 | 2007-10-04 | Ergonex Pharma Gmbh | Tergurid/Protergurid zur Behandlung von chronischen Schmerzen |
-
2009
- 2009-12-22 CN CN2009801524590A patent/CN102271667A/zh active Pending
- 2009-12-22 SG SG2011045671A patent/SG172315A1/en unknown
- 2009-12-22 JP JP2011542819A patent/JP2012513446A/ja active Pending
- 2009-12-22 KR KR1020117017268A patent/KR20110098965A/ko not_active Application Discontinuation
- 2009-12-22 BR BRPI0923556A patent/BRPI0923556A2/pt not_active Application Discontinuation
- 2009-12-22 AU AU2009331469A patent/AU2009331469A1/en not_active Abandoned
- 2009-12-22 WO PCT/EP2009/067768 patent/WO2010072774A2/de active Application Filing
- 2009-12-22 CA CA2748163A patent/CA2748163A1/en not_active Abandoned
- 2009-12-22 MX MX2011006852A patent/MX2011006852A/es not_active Application Discontinuation
- 2009-12-22 EP EP09795786A patent/EP2367543A2/de not_active Withdrawn
-
2011
- 2011-06-23 IL IL213768A patent/IL213768A0/en unknown
Non-Patent Citations (1)
Title |
---|
See references of WO2010072774A2 * |
Also Published As
Publication number | Publication date |
---|---|
CN102271667A (zh) | 2011-12-07 |
IL213768A0 (en) | 2011-07-31 |
WO2010072774A2 (de) | 2010-07-01 |
AU2009331469A1 (en) | 2011-07-21 |
SG172315A1 (en) | 2011-07-28 |
CA2748163A1 (en) | 2010-07-01 |
KR20110098965A (ko) | 2011-09-02 |
WO2010072774A3 (de) | 2010-09-23 |
MX2011006852A (es) | 2011-07-20 |
JP2012513446A (ja) | 2012-06-14 |
BRPI0923556A2 (pt) | 2016-01-26 |
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