EP2352493B1 - Utilisation therapeutique, dietetique ou cosmétique des composés ayant une activité specifique vers la caspase-3 et compositions les comprenant - Google Patents
Utilisation therapeutique, dietetique ou cosmétique des composés ayant une activité specifique vers la caspase-3 et compositions les comprenant Download PDFInfo
- Publication number
- EP2352493B1 EP2352493B1 EP09759916.1A EP09759916A EP2352493B1 EP 2352493 B1 EP2352493 B1 EP 2352493B1 EP 09759916 A EP09759916 A EP 09759916A EP 2352493 B1 EP2352493 B1 EP 2352493B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- spermidine
- zeaxanthin
- rutin
- composition
- quantities
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 102000003952 Caspase 3 Human genes 0.000 title 1
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- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
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- C—CHEMISTRY; METALLURGY
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- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/06—Benzopyran radicals
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Claims (19)
- Zéaxanthine, seule ou combinée avec soit de la rutine soit de la spermidine, soit à la fois de la rutine et de la spermidine, pour une utilisation dans le traitement de troubles du cuir chevelu y compris l'alopécie induite par une chimiothérapie, la pelade, l'alopécie androgène et l'effluve télogène.
- Utilisation de zéaxanthine, seule ou combinée avec soit de la rutine soit de la spermidine, soit à la fois de la rutine et de la spermidine, pour la fabrication d'une composition pharmaceutique, alimentaire ou cosmétique, pour une administration orale ou topique, appropriée pour traiter des troubles du cuir chevelu y compris l'alopécie induite par une chimiothérapie, la pelade, l'alopécie androgène et l'effluve télogène.
- Utilisation selon la revendication 2 caractérisée par l'utilisation de zéaxanthine et de rutine dans ladite composition.
- Utilisation selon la revendication 3 caractérisée par l'utilisation de zéaxanthine dans des quantités de 0,2 mg à 10 mg et de rutine dans des quantités de 0,5 mg à 25 mg dans ladite composition.
- Utilisation selon la revendication 2 caractérisée par l'utilisation de zéaxanthine, de rutine et de spermidine dans ladite composition.
- Utilisation selon la revendication 5 caractérisée par l'utilisation de zéaxanthine dans des quantités de 0,2 mg à 10 mg, de rutine dans des quantités de 0,5 mg à 25 mg et de spermidine dans des quantités de 0,05 à 0,5 mg dans ladite composition.
- Utilisation selon la revendication 5 caractérisée par l'utilisation de zéaxanthine, de rutine et de spermidine dans un rapport en poids de 4/5/1, respectivement, dans ladite composition.
- Utilisation selon la revendication 2 caractérisée par l'utilisation de zéaxanthine et de spermidine dans ladite composition.
- Utilisation selon la revendication 8 caractérisée par l'utilisation de zéaxanthine dans des quantités de 0,2 mg à 10 mg et de spermidine dans des quantités de 0,05 à 0,5 mg dans ladite composition.
- Composition pharmaceutique, alimentaire ou cosmétique pour une utilisation dans le traitement de troubles du cuir chevelu y compris l'alopécie induite par une chimiothérapie, la pelade, l'alopécie androgène et l'effluve télogène, caractérisée en ce qu'elle comprend en tant que principe actif de la zéaxanthine combinée avec soit de la rutine soit de la spermidine, soit à la fois de la rutine et de la spermidine, avec des excipients pour une administration topique sur le cuir chevelu.
- Composition selon la revendication 10 caractérisée en ce qu'elle comprend 0,0005 à 1% p/p de zéaxanthine.
- Composition selon la revendication 10 caractérisée en ce qu'elle comprend 0,0005 à 1% p/p de zéaxanthine et 0,0001 à 1 % p/p de trichlorhydrate de spermidine.
- Composition selon la revendication 10 caractérisée en ce qu'elle comprend 0,0005 à 1% p/p de zéaxanthine, 0,0005 à 1 % p/p de rutine, et 0,0001 à 1 % p/p de trichlorhydrate de spermidine.
- Composition pharmaceutique, alimentaire ou cosmétique pour une administration orale ou topique, destinée au traitement de troubles du cuir chevelu y compris l'alopécie induite par une chimiothérapie, la pelade, l'alopécie androgène et l'effluve télogène, caractérisée en ce qu'elle comprend en tant que principe actif de la zéaxanthine combinée avec de la spermidine, ou à la fois de la rutine et de la spermidine.
- Composition selon la revendication 14 caractérisée en ce qu'elle comprend de la zéaxanthine dans des quantités de 0,2 mg à 10 mg, de la rutine dans des quantités de 0,5 mg à 25 mg et de la spermidine dans des quantités de 0,05 à 0,5 mg.
- Composition selon la revendication 14 caractérisée en ce qu'elle comprend de la zéaxanthine, de la rutine et de la spermidine dans un rapport en poids de 4/5/1, respectivement.
- Composition selon la revendication 14 caractérisée en ce qu'elle comprend de la zéaxanthine et de la spermidine.
- Composition selon la revendication 17 caractérisée en ce qu'elle comprend de la zéaxanthine dans des quantités de 0,2 mg à 10 mg et de la spermidine dans des quantités de 0,05 à 0,5 mg.
- Composition selon la revendication 14 caractérisée en ce qu'elle comprend, par unité d'administration orale, 2 mg de zéaxanthine, 2,5 mg de rutine, et 0,285 mg de spermidine (correspondant à 0,5 mg de trichlorhydrate de spermidine).
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL09759916T PL2352493T3 (pl) | 2008-11-03 | 2009-10-30 | Stosowanie terapeutyczne, dietetyczne lub kosmetyczne związków o swoistej aktywności anty-apoptotycznej względem kaspazy-3, i kompozycje zawierające te związki |
| EP09759916.1A EP2352493B1 (fr) | 2008-11-03 | 2009-10-30 | Utilisation therapeutique, dietetique ou cosmétique des composés ayant une activité specifique vers la caspase-3 et compositions les comprenant |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08425704 | 2008-11-03 | ||
| PCT/EP2009/064368 WO2010060729A1 (fr) | 2008-11-03 | 2009-10-30 | Utilisation thérapeutique, alimentaire ou cosmétique de composés avec une activité spécifique anti-apoptotique dirigée contre la caspase-3, et compositions comprenant ces composés |
| EP09759916.1A EP2352493B1 (fr) | 2008-11-03 | 2009-10-30 | Utilisation therapeutique, dietetique ou cosmétique des composés ayant une activité specifique vers la caspase-3 et compositions les comprenant |
Publications (2)
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| EP2352493A1 EP2352493A1 (fr) | 2011-08-10 |
| EP2352493B1 true EP2352493B1 (fr) | 2013-12-11 |
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| US (1) | US8729033B2 (fr) |
| EP (1) | EP2352493B1 (fr) |
| JP (1) | JP5709217B2 (fr) |
| KR (1) | KR101747442B1 (fr) |
| CN (1) | CN102202659B (fr) |
| AU (1) | AU2009319185B2 (fr) |
| BR (1) | BRPI0921491A2 (fr) |
| CA (1) | CA2741746C (fr) |
| DK (1) | DK2352493T3 (fr) |
| ES (1) | ES2450390T3 (fr) |
| IL (1) | IL212567A (fr) |
| MX (1) | MX2011004482A (fr) |
| NZ (1) | NZ593180A (fr) |
| PL (1) | PL2352493T3 (fr) |
| PT (1) | PT2352493E (fr) |
| RU (1) | RU2504366C2 (fr) |
| UA (1) | UA103340C2 (fr) |
| WO (1) | WO2010060729A1 (fr) |
| ZA (1) | ZA201104079B (fr) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2600858A4 (fr) | 2010-08-04 | 2014-03-05 | Tixupharma | Complexes supramoléculaires de polymères polyanioniques et de spermidine utilisés dans l'entretien et la réparation tissulaire |
| CH705756B1 (de) * | 2011-11-13 | 2016-03-31 | Compad Consulting Gmbh | Nachhaltige kosmetische und dermatologische Zubereitungen. |
| JP6092039B2 (ja) * | 2013-08-02 | 2017-03-08 | 富士フイルム株式会社 | 乳化組成物 |
| JP6092038B2 (ja) * | 2013-08-02 | 2017-03-08 | 富士フイルム株式会社 | 乳化組成物 |
| FR3009955B1 (fr) * | 2013-08-30 | 2016-11-25 | Laboratoires Inneov | Composition a base d'acide gras polyinsature et de vitamine d destinee a une administration par voie orale pour ameliorer la qualite de la chevelure |
| CA3009197A1 (fr) | 2015-12-31 | 2017-07-06 | Colgate-Palmolive Company | Compositions de nettoyage |
| CN105969725B (zh) * | 2016-06-12 | 2019-04-26 | 暨南大学 | 枸杞红素的用途 |
| RU2631642C1 (ru) * | 2016-11-29 | 2017-09-25 | Общество с ограниченной ответственностью "Научно-производственная компания Стемма" | Способ лечения нерубцовой алопеции |
| CN110882173B (zh) * | 2019-12-05 | 2022-06-17 | 西北农林科技大学 | 一种靶向毛囊干细胞防治脱发的外用型日化品配方 |
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| JPH072677A (ja) * | 1993-06-18 | 1995-01-06 | Toyo Seito Kk | 経口育毛剤 |
| US6218436B1 (en) * | 1993-06-28 | 2001-04-17 | The Howard Foundation | Pharmaceutically active carotenoids |
| GB9419715D0 (en) * | 1994-09-30 | 1994-11-16 | Boots Co Plc | Hair stimulant composition |
| US20060264357A1 (en) * | 1997-04-22 | 2006-11-23 | Zikria Bashir A | Capillary membrane stabilization and reduction of tissue injury through use of biodegradable macromolecules with antioxidants and/or other chemicals |
| US6573299B1 (en) * | 1999-09-20 | 2003-06-03 | Advanced Medical Instruments | Method and compositions for treatment of the aging eye |
| WO2001076541A1 (fr) * | 2000-04-07 | 2001-10-18 | Taisho Pharmaceutical Co. Ltd. | Compositions stimulant la pousse des cheveux |
| US6254898B1 (en) | 2000-05-25 | 2001-07-03 | Protective Factors, Inc. | Nutraceutical composition for protection against solar radiation |
| JP2002029989A (ja) * | 2000-07-12 | 2002-01-29 | Mitsuyo Kamata | 鍼灸による脱毛治療の育毛を促進する経口剤 |
| FR2811569B1 (fr) * | 2000-07-13 | 2003-03-14 | Oreal | Composition, notamment cosmetique, renfermant la dhea et/ou ses precurseurs ou derives, et un carotenoide |
| FR2815541B1 (fr) * | 2000-10-24 | 2008-02-29 | Lipha | Utilisation d'inhibiteurs de l'apoptose des pericytes pour le traitement et/ou la prevention de la retinopathie diabetique |
| ITMI20020189A1 (it) * | 2002-02-01 | 2003-08-01 | Giuliani Spa | Composizione per uso farmaceutico o dietetico per contrastare la caduta dei capelli |
| ES2774911T3 (es) * | 2002-06-21 | 2020-07-23 | Oreal | Utilización de la taurina o derivados para el tratamiento de la alopecia |
| US8088363B2 (en) * | 2002-10-28 | 2012-01-03 | Zeavision Llc | Protection against sunburn and skin problems with orally-ingested high-dosage zeaxanthin |
| CN1481804A (zh) * | 2002-12-17 | 2004-03-17 | 无锡杰西医药科技有限公司 | 防治白内障、黄斑变性等眼病的配方及其使用方法 |
| JP4535827B2 (ja) * | 2004-09-29 | 2010-09-01 | 株式会社マンダム | アポトーシス誘導阻害剤及びその評価方法 |
| EP1827408A1 (fr) * | 2004-12-03 | 2007-09-05 | Nu-Tein Co., Inc. | Methode de traitement de troubles cutanes au moyen de xanthophylles |
| RU2008119234A (ru) * | 2005-10-16 | 2009-11-27 | Ликорд Лтд. (Il) | Композиции для лечения глазных заболеваний |
| JP2008007476A (ja) * | 2006-06-30 | 2008-01-17 | Lion Corp | 育毛養毛剤組成物 |
| JP2008127505A (ja) * | 2006-11-22 | 2008-06-05 | Q P Corp | 粉末状組成物およびその製造方法、ならびにこれを含有する食品組成物 |
| ITMI20070555A1 (it) * | 2007-03-21 | 2007-06-20 | Giuliani Spa | Composizione provvista di attivita' di inibizione sulla 5 alfa-reduttasi |
-
2009
- 2009-10-30 WO PCT/EP2009/064368 patent/WO2010060729A1/fr active Application Filing
- 2009-10-30 JP JP2011533740A patent/JP5709217B2/ja not_active Expired - Fee Related
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- 2009-10-30 NZ NZ593180A patent/NZ593180A/xx not_active IP Right Cessation
- 2009-10-30 PT PT97599161T patent/PT2352493E/pt unknown
- 2009-10-30 KR KR1020117012264A patent/KR101747442B1/ko active IP Right Grant
- 2009-10-30 EP EP09759916.1A patent/EP2352493B1/fr active Active
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- 2009-10-30 UA UAA201106636A patent/UA103340C2/ru unknown
- 2009-10-30 CN CN200980143229.8A patent/CN102202659B/zh not_active Expired - Fee Related
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Also Published As
| Publication number | Publication date |
|---|---|
| NZ593180A (en) | 2012-09-28 |
| CN102202659A (zh) | 2011-09-28 |
| DK2352493T3 (da) | 2014-02-10 |
| RU2504366C2 (ru) | 2014-01-20 |
| KR101747442B1 (ko) | 2017-06-14 |
| AU2009319185A1 (en) | 2011-06-23 |
| IL212567A0 (en) | 2011-06-30 |
| EP2352493A1 (fr) | 2011-08-10 |
| IL212567A (en) | 2015-08-31 |
| ES2450390T3 (es) | 2014-03-24 |
| AU2009319185B2 (en) | 2013-11-14 |
| US8729033B2 (en) | 2014-05-20 |
| CA2741746A1 (fr) | 2010-06-03 |
| CN102202659B (zh) | 2014-04-16 |
| ZA201104079B (en) | 2012-02-29 |
| PT2352493E (pt) | 2014-03-20 |
| US20110218164A1 (en) | 2011-09-08 |
| UA103340C2 (ru) | 2013-10-10 |
| CA2741746C (fr) | 2016-08-23 |
| KR20110086126A (ko) | 2011-07-27 |
| JP2012507489A (ja) | 2012-03-29 |
| WO2010060729A1 (fr) | 2010-06-03 |
| MX2011004482A (es) | 2011-05-31 |
| BRPI0921491A2 (pt) | 2016-07-19 |
| JP5709217B2 (ja) | 2015-04-30 |
| PL2352493T3 (pl) | 2014-05-30 |
| RU2011122458A (ru) | 2012-12-10 |
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