EP2175827B1 - Vorrichtung und verwendung zum aufbewahren und bereitstellen von arzneimittel-wafern - Google Patents

Vorrichtung und verwendung zum aufbewahren und bereitstellen von arzneimittel-wafern Download PDF

Info

Publication number
EP2175827B1
EP2175827B1 EP08785171A EP08785171A EP2175827B1 EP 2175827 B1 EP2175827 B1 EP 2175827B1 EP 08785171 A EP08785171 A EP 08785171A EP 08785171 A EP08785171 A EP 08785171A EP 2175827 B1 EP2175827 B1 EP 2175827B1
Authority
EP
European Patent Office
Prior art keywords
medicament
pouches
provision
storage
stack
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Not-in-force
Application number
EP08785171A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP2175827A1 (de
Inventor
Sabine Leifeld
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Bayer Schering Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma AG filed Critical Bayer Schering Pharma AG
Publication of EP2175827A1 publication Critical patent/EP2175827A1/de
Application granted granted Critical
Publication of EP2175827B1 publication Critical patent/EP2175827B1/de
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0481—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers working on a schedule basis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/04—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills
    • B65D83/0445—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills all the articles being stored in individual compartments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2200/00—General characteristics or adaptations
    • A61J2200/30—Compliance analysis for taking medication
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2205/00—General identification or selection means
    • A61J2205/30—Printed labels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/078—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of wafers or cachets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2583/00—Containers or packages with special means for dispensing contents
    • B65D2583/04—For dispensing annular, disc-shaped or spherical or like small articles or tablets
    • B65D2583/0404—Indications, e.g. directions for use
    • B65D2583/0409—Indications, e.g. directions for use of dates or follow-numbers

Definitions

  • the invention relates to a device and a use for storing and providing drug wafers, i. of drugs in a layered form, in particular for contraception (contraception) or for hormone replacement therapy.
  • Drug wafers are sheet-like devices containing pharmaceutically active agents contained in a drug carrier.
  • the active substances in the wafers can be administered, for example, transmucosally, ie via the oral mucosa, by placing the wafers on or under the tongue, whereby the active substance carrier dissolves, thereby releasing the active substances.
  • the wafers are provided enclosed in foil pockets. According to DE 101 59 746 B4 These pockets may consist of at least one carrier foil and at least one cover foil, wherein at least the areal larger foil has two parallel side edges and between the carrier foil and the cover foil the foil- or sheet-like material (wafer) is enclosed gas- and moisture-proof.
  • Devices for storing and providing the drug wafers may contain foil bags stacked therein.
  • the DE 101 59 746 B4 described device for storing and providing the wafer comprises an at least single-divided housing, abutting on the lateral inner sides of the side edges of the stacked film pockets, while on a front inside that edge of a carrier film is present, which protrudes beyond the edge of an associated cover sheet and wherein the stacked film pockets spring-loaded pressed against the upper inside of the housing.
  • the front, upper portion of the housing has two slots for separately dispensing the carrier film and the cover film, wherein the wafer can be provided with the carrier film or with the cover film. Between the slots, a separating tool for separating the carrier film from the cover sheet is arranged, against which the uppermost carrier film rests with its lying in front of the front edge of the cover sheet area.
  • To transport the drug pockets from the housing serves a rotatable about a rotation axis transport element.
  • This device has the disadvantage that a user does not receive any control as to whether or not a prescribed intake for a certain period of time has already been followed. Therefore, it can easily come to a double intake, or the user ever forgets to take the wafer.
  • a blister is provided with in-line pockets for the tablets, wherein the pockets correspond in a one-to-one manner to the days of at least one calendar month, further comprising consecutive integer numerical indications arranged in a one-to-one relation near the pockets such that each pocket includes a and is identifiable visually only one calendar day of the calendar month, and wherein consecutive integer numerical indications of near breakable zones in the second film are arranged to be visible on the second film from the back, and wherein each zone is one and only one calendar day Calendar month is visually identifiable.
  • This allows each pocket to be visually identified from both the front and back with one and only one calendar day.
  • EP 0 511 726 B1 describes an assembly for receiving tablets in a field, comprising: a blister pack having a predetermined area in which a plurality of tablets configured in a selected field are located, a container for receiving the blister pack, and a daily calendar placed on the panel of the tablets can be aligned in the blister pack, with the daily calendar being displaceable by one to position a selected starting day on a first tablet in the field of tablets, and wherein pointers are provided on the container and the blister pack has a locating notch close to and in proximity to a first tablet so that the first tablet to be withdrawn is displayed.
  • the first Etuihtag is designed as a pocket for receiving the blister pack and has an outer part and an inner visible part and first openings in the visible part and second openings in the outer part, wherein the first openings are aligned with the second openings at least where the containers for the tablets are in the blister pack after picking up in the bag.
  • the second half of the case has a compartment for receiving a display of the days of the week and windows for displaying the days of the week in an inner visible area of the second half of the compartment in the area of the compartment, wherein the windows are arranged such that they correspond to the columns of the containers of one received in the pocket Blister pack are assigned.
  • Another object of the present invention is to ensure that the wafers are safely taken out of the device at a predetermined rhythm, i. the device is suitable for allowing the user (s) to control the prescription of a drug wafer over a certain period of time.
  • Yet another object of the present invention is to provide a device for storing and providing the drug wafers which is suitable for everyday use, which has the required mechanical stability and which can be produced easily and simply and thus inexpensively.
  • Yet another object of the present invention is to provide secure storage for the drug wafers.
  • a drug pocket of the inventive device consists of a base sheet and a cover sheet.
  • the cover film can be connected, for example glued, to the base film by way of a preferably strip-shaped connection extending along the side edges of the cover film.
  • the base film and the cover film may each have on each at least one side edge protruding tabs which are not connected to each other.
  • the device according to the invention which serves for storing and providing drug wafers, contains drug pockets arranged in a pocket stack with drug wafers contained therein.
  • a carrier is arranged substantially parallel to an edge of the drug pockets.
  • a time stamp is affixed to the carrier and a marking is affixed to each drug bag, so that one on the other in the bag stack following markings on the carrier are aligned with successive times.
  • the drug pockets are arranged in the device in a stack of bags and provided with mutually staggered markings and preferably and arranged substantially parallel to an edge of the drug pockets on a carrier display means for timings for taking the wafer, a (e) Always check if a wafer has been taken in a current intake period or if this is not the case.
  • the drug pockets may preferably be connected to the edge of the carrier.
  • the carrier is formed by stacks of sheets arranged in a stack of sheets. These staples are connected to each other at least in the region of a respective first sheet edge. Further, in this case, each drug pouch is associated with one of the leaflet sheets over a respective second sheet edge opposite the first sheet edge, which also includes integrally forming the leaflet sheets with the drug pouches, i.
  • the medicine bags are widened at one edge and form at this widened edge in each case the Heftquo.
  • the times are applied to a staple sheet lying in the top of the sheet stack along its second sheet edge or on a tab covering the staple sheet above, which together then form the support.
  • the carrier may also be disposed adjacent to a first edge of the drug pouches opposite to a second edge of the drug pouches at which the drug pouches with the pellicle sheets overlay a respective second sheet edge opposite the first sheet edge of the pellicle sheets Staples are connected.
  • the drug pouches with the wafers contained therein are stacked by the chosen design of the device as in a booklet or book and can be sequentially preferably removed from above.
  • the top pocket is removed in a first intake period, the underlying bag in the stack is visible. This underlying pocket can then be removed during a subsequent second intake period.
  • the other pockets with the wafers can be removed according to the order of the pockets in the stack.
  • the pockets are each connected to staples and are held over these in the stack.
  • a pocket in one embodiment may be removed from the staple sheet to which it is attached by severing it.
  • each bag may be removed from the stack along with the associated staple sheet, such as by tearing or stapling.
  • the / can User must always determine if a bag with a wafer has been removed from the stack during the current collection period and the wafer has been ingested or if it is not. This can be seen from the fact that the mark located on the bag is aligned with a certain time on the next arranged carrier, preferably overhead stapling sheet. As a result, the user (in) recognizes whether the current time falls within the time period indicated by the time or whether this is not the case.
  • Forms a stack of sheets the carrier are in a first embodiment in which each bag is removed from the associated stapling sheet by separating from the stack, times only on an overhead stapling sheet, since only this overhead staple sheet is always visible.
  • a stack of sheets forms the carrier and in which each pocket is removed from the stack together with the associated stapling sheet, not only the stapling sheet above, but each staple sheet which is connected to a pocket, with the Times are provided, since the sheets are removed when removing the bags each with.
  • the carrier is formed in each case by the current top staple sheet together with all the remaining stapling sheets.
  • the first embodiment is preferable to the second embodiment.
  • each drug pocket is separably connected to one of the staple sheets, for example by a perforation. This will allow the pockets to be easily removed from the stack, such as through Tearing out.
  • Each of the pockets can be made with an associated booklet sheet in one unit, such as by the components of the pockets (base film, cover film) are made widened on one side. This formed by the widening part corresponds to the booklet.
  • the times are weekdays or calendar days, the latter represented by the numbering of the days of a month.
  • Weekday data have the advantage over the calendar day data, on the one hand, that the repetition rhythm takes place more frequently than in the latter. This allows for easier attachment of time information on the carrier or an overhead leaflet, since for the first day only the appropriate day of the week must be selected from all seven days of the week, while in the case of calendar days the appropriate calendar day from 28, 29, 30 or 31 Calendar days must be selected.
  • calendar days at least as many calendar days are to be affixed to the carrier or topmost stapling sheet (depending on the month, however, not more than 28, 29, 30 or 31 statements), as pockets are contained in the stack, since a repetition of the calendar day information only with the beginning of a new month.
  • the length may be 28, 29, 30 or 31 days. This can easily lead to incorrect operation of the device. Therefore, the times are preferably weekdays. In this case, very particular preference is given to seven weekday indications on the carrier, preferably on the stapling sheet lying in the top of the sheet stack.
  • the weekdays, calendar days or other times are preferably applied at the beginning of a take-up phase of the wafers on the carrier, preferably the overhead stapling sheet.
  • the user brings the time information on the carrier, preferably along the sheet edge, so that the time of the first intake period, about the first intake day, either at the top, depending on the sequence of markings on the successive drug bags or at the bottom and following times, such as weekday, below, and above, of course, keeping the grid of markings on the medicine bags for the application of time so that the times are aligned with the marks.
  • the time information is preferably displayed on the carrier, in particular along the second sheet edge, by applying a time-indicative display means to the carrier applied.
  • a display strip containing the times can be attached by insertion into a holder on the carrier or by sticking to the carrier.
  • the holder may be, for example, a slot in the carrier which has windows in the region of the time indications applied to the inserted display strip, which releases the view of the times and allows the association with a mark aligned therewith on the overhead medicine bag.
  • such a display strip may initially have about twice as many successive times as can be accommodated on the sheet edge in order to be able to prepare the display strip for mounting on the carrier in a suitable manner.
  • the associated time indication on the display strip is assigned to the upper or lower position on the carrier and the length of the display strip then, based on this determined time indication, reduced to the length range of the available length corresponds to the carrier.
  • the display strip for attachment to the carrier may be kinked or trimmed above or below the time of first taking. Upwards or downwards protruding parts of the display strip can also be bent or cut off.
  • the thus prepared display strip is then mounted in the holder on the carrier, for example, inserted into this or clamped there, or glued to the carrier so that the times are aligned with the markings on the drug bags.
  • time information can be applied to the carrier also by hand.
  • the stapling sheets are preferably joined together by clamping, gluing, stapling or a ring or a spiral binding.
  • the sheets can be connected to each other, for example, by surface bonding, such as sticking together, in the region of its edge.
  • the stitching sheets may be hinged together. The latter is achieved by connecting the staples exclusively or substantially over the edges of the first sheet edge.
  • the sheets are connected to each other by a ring binding or a spiral binding, as in a notebook, or hinged together.
  • an additional cover may be attached, for example, on the carrier or on the side opposite the carrier of the bag stack.
  • This lid can rest against the pocket stack when closed.
  • the lid may be fastened to the carrier, particularly preferably articulated, and in another embodiment on the side of the pocket stack opposite the carrier.
  • the lid may be provided primarily for the protection of drug bags.
  • the lid is preferably made of a stable material, such as cardboard or plastic.
  • On the lid may also be attached a label or a logo or a different design, which does not fulfill exclusively or no functional purposes but also or exclusively aesthetic purposes.
  • a lid connected thereto in the region of the carrier which engages over both sides of the pocket stack by being folded back on a side edge of the drug pockets opposite the carrier.
  • a lid can be folded or folded from a cardboard or plastic sheet.
  • the lid may be connected by one of its edges to the carrier and spaced therefrom and preferably parallel to a fold, which allows the sudfalzung over the bag stack.
  • the cover can thus completely cover both the front and the back of the bag stack and thus protect it effectively.
  • the fold in the lid is preferably designed to be broad enough to comfortably encase the thickness of the pocket stack.
  • the top bag is protected in the closed state of the lid from the free folded back front portion of the lid, while the rear part of the lid, which is connected to the carrier protects the back of the bag stack. Furthermore, in the region in which it is connected to the carrier, the lid can be folded over the connection point to the front and over the stack of sheets and cover it there.
  • the carrier is formed by the sheet stack and the lid folded around. This also protects the stack of sheets from mechanical damage. Therefore, the time indications according to the present invention may be placed on a tab on the sheet stack instead of on the sheet stack resulting from the folding of the lid over the stack of sheets.
  • the sheet stack and the tab in this case together form the carrier.
  • Such structures are known, for example, from matchbooks. Their production is simple and efficient.
  • the cover which engages over both sides of the device can also be fastened to the device on the side of the pocket stack opposite the stack of sheets and be folded back over the side on which the stack of sheets is arranged.
  • the carrier may be arranged, for example, on the side of the bag stack opposite the stack of sheets, and the fold of the lid forms, for example, the carrier.
  • the device of the invention may preferably contain 120 drug pockets for containing drug wafers in a pocket stack.
  • 120 drug pockets may be provided in the device.
  • a device for storing and providing wafers is shown.
  • the device consists of a cover 2, for example made of plastic, and a plurality of drug pouches 1 in which the wafers are enclosed (not shown).
  • a further lid (not shown) may be arranged to protect the drug pouches 1 against mechanical damage.
  • Each of the medicine pouches 1 has laterally a stapling sheet 3, which is separated at a second sheet edge 3 "from the medicament pouch 1 only by a perforation 4.
  • the perforation 4 serves a medicament pouch 1 as needed from the stapling sheet 3 to tear this bag 1 out of the device
  • the stapling sheet 3 remains in. This is in Fig.
  • the overhead medicament pouch 1.1 is already torn away from the overhead stapling sheet 3.1 and a stapled medicament pouch 1.2 becomes visible which is still connected via the perforation 4 to the associated stapling sheet (not visible).
  • 120 pharmaceutical bags 1 may be provided in the device.
  • the lid 2 has a label which is used, for example, for instructions for use and to identify the drug and the manufacturer.
  • the medicine bags 1 with the associated stapling sheets 3 and the cover 2 are connected to each other in the manner of a binding bound with a ring binding.
  • first perforations 6 in each case a first sheet edge 3 'of the Heftge 3 on each drug-bag 1 and second holes 7 in one of the cover edges 7', reach through the rings 5 of the ring bond.
  • the stapling sheets 3 form a stack of sheets, which forms a carrier 9 for times.
  • time indications are applied to the uppermost stapling sheet 3.1, which are applied to a weekday strip 10.
  • the times in this case represent weekdays, here represented by the letters "M" (Monday), “D” (Tuesday), “M” (Wednesday), “D” (Thursday), “F” (Friday), “ S “(Saturday),” S “(Sunday).
  • This weekday strip is in this case adhered to the upper stapling sheet 3.1.
  • the weekday "M” for Monday is applied at the bottom, and the other day of the week follow chronologically upwards.
  • the day of the week "S” for Sunday is the last in this series.
  • the weekday strip 10 By this selection of the arrangement of the weekday data on the weekday strip 10 is clearly determined that the first wafer is to be taken on a Monday. If, for example, the first wafer had to be taken on a Thursday (corresponding to "D"), the weekday strip 10 would have had to be glued differently onto the upper stapling sheet 3.1, namely in the order (from below): D, F, S, S, M, D, M. The same applies to other income rhythms. Therefore, it is preferable to provide a user with a weekday strip 10 for preparation of the device prior to commencement of administration, on which all weekday data are printed approximately twice in the weekday order, so that the user can prepare the row of 7 weekday indications starting on the display strip 10 starting with the selected starting day of the week. The unneeded end portions of the weekday strip 10 are then cut off (or optionally kinked when the strip 10 is mounted in a holder or inserted into a slot).
  • Marks 20 are also attached to the drug pouches 1.
  • the underlying pharmaceutical bag 1.2 which becomes visible as a result of tearing off the medicine bag 1. 1 lying overhead, carries a second marking 22, which is aligned with the day of the week "D" for Tuesday on the weekday strip 10. Therefore, the wafer is to be taken in this second bag 1.2 on a Tuesday. Further markings 23, 24, 25, 26, 27 are only indicated because they are concealed in the order given on the subsequent drug pockets 1.
  • a second embodiment of the invention is shown.
  • the device in turn has a lid 2, for example made of cardboard, and medicine bags 1.
  • the cover 2 here also has a label which can be used for the information leaflet and for the identification of the drug and the manufacturer.
  • the lid 2 may be connected to a stack of sheets by gluing. This sheet stack consists of several sheets of 3, which are glued together. These booklets 3 are separated from the drug bags 1 by a perforation 4.
  • the required carrier and cover films are prepared in a suitable size, so as not only to form the medicine bag 1, but at the same time also the subsequent stapling sheet 3. and / or cover sheets suitably larger than is required for the inclusion of the wafer.
  • the drug pockets 1 are stacked with the stapling sheets 3 for producing the device, and the stapling sheets 3 are glued exclusively in the area of the stapling sheets 3.
  • the sheet stack formed by gluing the sheets 3 may be connected to the cover 2 via an adhesive bond.
  • the cover 2 is folded back to form a tab 15 towards the pocket stack.
  • the carrier 9 is formed for the time information.
  • the lid 1 forms an upper fold 11, so that the lid 2 can be folded back over the front of the pocket stack.
  • a weekday strip 10 is applied by sticking, which has the weekdays "M", “D”, “M”, “D”, “F”, “S”, “S”.
  • the strip is like in the example of Fig. 1 prepared, so that the beginning of the week indication appear on the leftmost on the strip 10, and glued to the carrier 9.
  • 1 marks 20 are applied to the medicine bags, which are aligned with the weekday information on the weekday strip 10.
  • a first mark 21 is aligned with the day of the week "M” and a second mark 22 aligned with the day of the week “D” is shown on the medicine bag 1.2 below. This is only indicated here. Further markings are not shown because they are hidden by the preceding drug pockets 1.
  • Fig. 3 the second embodiment of the device according to the invention is shown in the closed state. On the outside of the lid 2, a label and logos can be applied.
  • a third embodiment of the device according to the invention is shown.
  • This device is made like a matchbook.
  • the lid 2 is provided on the inside with a label, such as instructions for use, including the drug name and the manufacturer's name.
  • the lid 2 forms in the lowermost portion of the device a tab 15 through a lower fold by the lid 2 is guided around a stack of stapling sheets 3 around and fixed there.
  • the lid 2 does not completely cover the stapling sheets 3.
  • the stack of sheets protrudes partially in relation to the tab 15.
  • the lid 2 protects the back of the bag stack and is at an upper fold 11 on the Front of the device kinked so that it can protect the front of the bag stack against mechanical damage.
  • the stapling sheets 3 are connected via a perforation 4 with associated drug pockets 1.
  • the medicine bags with the associated stapling sheets 3 can be made in one piece. With the help of the perforation 4, the two parts can be separated from each other.
  • a weekday tag 10 is affixed to the carrier 9 and contains the weekday indications "M", “D”, “M”, “D”, “F”, "S", “S”
  • the weekday series starts with “M” for Monday and ends with “S” for Sunday
  • a first overhead medicine bag 1.1 is torn off the carrier 3 thanks to the perforation 4.
  • a portion of the top stapling sheet 3.1 is visible, and the severed pocket 1.1 has a first mark 21 which has been aligned with "M" for Monday, and an underlying medicine pouch 1.2 is visible This second pouch 1.2 has a second mark 22 Aligning the markers 20 with the days of the week makes it possible for the user (s) to know whether a wafer has already been taken during the current intake period or whether this is not the case fa ll is.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mechanical Engineering (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Packages (AREA)
  • Sheets, Magazines, And Separation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Bag Frames (AREA)
EP08785171A 2007-08-06 2008-07-29 Vorrichtung und verwendung zum aufbewahren und bereitstellen von arzneimittel-wafern Not-in-force EP2175827B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102007037374A DE102007037374B4 (de) 2007-08-06 2007-08-06 Vorrichtung und Verwendung zum Aufbewahren und Bereitstellen von Arzneimittel-Wafern
PCT/EP2008/006223 WO2009018938A1 (de) 2007-08-06 2008-07-29 Vorrichtung und verwendung zum aufbewahren und bereitstellen von arzneimittel-wafern

Publications (2)

Publication Number Publication Date
EP2175827A1 EP2175827A1 (de) 2010-04-21
EP2175827B1 true EP2175827B1 (de) 2011-05-11

Family

ID=39931801

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08785171A Not-in-force EP2175827B1 (de) 2007-08-06 2008-07-29 Vorrichtung und verwendung zum aufbewahren und bereitstellen von arzneimittel-wafern

Country Status (24)

Country Link
US (1) US7987986B2 (es)
EP (1) EP2175827B1 (es)
JP (1) JP2010535549A (es)
KR (1) KR20100055452A (es)
CN (1) CN101778615B (es)
AR (1) AR068092A1 (es)
AT (1) ATE508726T1 (es)
AU (1) AU2008285961A1 (es)
BR (1) BRPI0815019A2 (es)
CA (1) CA2695582A1 (es)
CL (1) CL2008002299A1 (es)
CO (1) CO6251231A2 (es)
CR (1) CR11256A (es)
DE (1) DE102007037374B4 (es)
EA (1) EA201000270A1 (es)
EC (1) ECSP109941A (es)
ES (1) ES2364527T3 (es)
MX (1) MX2010001465A (es)
PA (1) PA8792201A1 (es)
PE (1) PE20090850A1 (es)
TW (1) TW200924734A (es)
UY (1) UY31269A1 (es)
WO (1) WO2009018938A1 (es)
ZA (1) ZA201001633B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2082717A1 (en) * 2008-01-28 2009-07-29 Merz Pharma GmbH & Co. KGaA Titration package
DE102009008027A1 (de) * 2009-02-06 2010-08-12 Bayer Schering Pharma Aktiengesellschaft Vorrichtung und Verwendung zur Aufbewahrung und Bereitstellung von Arzneimittelwafern
EP2393467A1 (de) * 2009-02-06 2011-12-14 Bayer Pharma Aktiengesellschaft Verfahren zur herstellung eines stapels von zur aufbewahrung und bereitstellung von arzneimittelwafern dienenden arzneimitteltaschen, arzneimitteltaschenvorlage zur herstellung des stapels sowie verwendung der arzneimitteltaschenvorlage
WO2012072491A1 (de) * 2010-11-29 2012-06-07 Bayer Pharma Aktiengesellschaft Spender zur aufbewahrung und bereitstellung eines stapels von jeweils einen wafer enthaltenden wafertaschen
JP5590635B1 (ja) * 2013-12-16 2014-09-17 建治 藤井 Ｐｔｐシート吊り具及び服用管理器具
AU2015305661B2 (en) * 2014-08-19 2020-05-28 Mylan Inc. Medication packaging and dose regimen system
WO2017044568A1 (en) * 2015-09-08 2017-03-16 Accredo Health Group, Inc. Medication dispensing system
JP6921400B2 (ja) * 2017-05-25 2021-08-18 ハンドメディカル株式会社 日めくり服薬支援カレンダー及び卓上型日めくり服薬支援カレンダーセット

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1719962A (en) * 1929-07-09 Display holbek
GB1601885A (en) * 1978-05-30 1981-11-04 Sterwin Ag Packaging
US4534468A (en) 1983-12-19 1985-08-13 Nuckols Walter S Calendar-oriented pill dispenser
US4972657A (en) * 1988-01-11 1990-11-27 Rna, Incorporated Method of packaging medication for controlled dispensing
ATE155340T1 (de) 1991-04-29 1997-08-15 Berlex Lab Vorrichtung zum halten von tabletten in blisterverpackungen
US5169001A (en) * 1991-07-19 1992-12-08 Scheibel David H Medicament dispensing container
US6568533B1 (en) * 1998-06-16 2003-05-27 Takeda Chemical Industries, Ltd. Peelable package and peelable packaging method
JP2000272659A (ja) * 1998-12-15 2000-10-03 Takeda Chem Ind Ltd ピール性包装体及びピール性包装方法
DE19911799A1 (de) * 1999-03-17 2000-09-28 Lohmann Therapie Syst Lts Sammelpackung zur Entnahme von befüllten Beuteln in vorgebener Reihenfolge
DE19950781A1 (de) * 1999-10-21 2001-04-26 Knoll Ag Mehrteiliges Etikett für Durchdrückpackungen, seine Herstellung und Verwendung
JP2003079419A (ja) * 2001-09-17 2003-03-18 Katsuyoshi Yamazaki 携帯用ブック式薬入れカレンダー
DE10159746B4 (de) 2001-12-05 2006-05-18 Lts Lohmann Therapie-Systeme Ag Spendevorrichtung für flächenförmige Darreichungsformen
US6708826B1 (en) * 2003-04-30 2004-03-23 Warner-Lambert Company, Llc Packaged supply of individual doses of a personal care product
US20060104910A1 (en) * 2004-11-15 2006-05-18 Keith Lerner Over dosage indicating medicated film strip
US20060157375A1 (en) * 2005-01-20 2006-07-20 Dejonge Stuart W Child resistant blister pack container for stacked blister packs with non-coincidental notching
JP3112062U (ja) * 2005-04-28 2005-07-28 有限会社産栄 服用時表示付き薬入れ
DE102005032015A1 (de) 2005-07-01 2007-01-04 Schering Ag Etui zur Aufnahme einer Arzneimittelpackung sowie deren Verwendung
DE102005042374B3 (de) * 2005-09-07 2006-10-05 Lts Lohmann Therapie-Systeme Ag Verpackungseinheit mit feuchtigkeitsaufnehmenden filmaratigen Materialien

Also Published As

Publication number Publication date
ES2364527T3 (es) 2011-09-06
UY31269A1 (es) 2009-03-31
CN101778615A (zh) 2010-07-14
KR20100055452A (ko) 2010-05-26
ZA201001633B (en) 2011-05-25
US7987986B2 (en) 2011-08-02
CO6251231A2 (es) 2011-02-21
ECSP109941A (es) 2010-03-31
BRPI0815019A2 (pt) 2015-03-10
CA2695582A1 (en) 2009-02-12
MX2010001465A (es) 2010-03-01
AU2008285961A1 (en) 2009-02-12
TW200924734A (en) 2009-06-16
ATE508726T1 (de) 2011-05-15
AR068092A1 (es) 2009-11-04
CL2008002299A1 (es) 2010-01-15
PE20090850A1 (es) 2009-08-08
DE102007037374B4 (de) 2009-04-23
EA201000270A1 (ru) 2010-08-30
US20090038981A1 (en) 2009-02-12
CR11256A (es) 2010-05-20
EP2175827A1 (de) 2010-04-21
PA8792201A1 (es) 2009-04-23
JP2010535549A (ja) 2010-11-25
DE102007037374A1 (de) 2009-02-12
CN101778615B (zh) 2013-06-12
WO2009018938A1 (de) 2009-02-12

Similar Documents

Publication Publication Date Title
EP2175827B1 (de) Vorrichtung und verwendung zum aufbewahren und bereitstellen von arzneimittel-wafern
EP1094430B1 (de) Mehrteiliges Etikett für Durchdrückpackungen, seine Herstellung und Verwendung
DE202004021140U1 (de) Neue Arzneimittelverpackung
DE102005032015A1 (de) Etui zur Aufnahme einer Arzneimittelpackung sowie deren Verwendung
EP2393466A1 (de) Vorrichtung und verwendung zur aufbewahrung und bereitstellung von arzneimittelwafern
WO2000055061A1 (de) Sammelpackung zur entnahme von befüllten beuteln in vorgegebener reihenfolge
DE102004034024A1 (de) Verpackungseinheit für den wöchentlichen Medikamentenbedarf eines Patienten
EP1107213A2 (de) Mehrteiliges Etikett, seine Herstellung und Verwendung
EP2203359A2 (de) Verpackungseinheit
EP1108413B1 (de) Verwendung einer Blisterpackung
EP0360925B1 (de) Verpackungseinheit für Papiertaschentücher
WO2010089091A1 (de) Verfahren zur herstellung eines stapels von zur aufbewahrung und bereitstellung von arzneimittelwafern dienenden arzneimitteltaschen, arzneimitteltaschenvorlage zur herstellung des stapels sowie verwendung der arzneimitteltaschenvorlage
DE202019102748U1 (de) Medikamentendispenser aus Zellstoff
EP0129713A2 (de) Ablagemappe
WO2011076831A1 (de) Spender für wafer enthaltende wafertaschen und wafertaschenheft
WO2011076830A1 (de) In einen spender einsetzbares wafertaschenheft und spender für wafer enthaltende wafertaschen
DE102009008028A1 (de) Verfahren zur Herstellung eines Taschenstapels von zur Aufbewahrung und Bereitstellung von Arzneimittelwafern dienenden Arzneimitteltaschen
DE102009008026A1 (de) Verfahren zur Herstellung eines Stapels von Arzneimitteltaschen, Arzneimitteltaschenvorlage zur Herstellung des Stapels sowie Verwendung der Arzneimitteltaschenvorlage
DE20212941U1 (de) Faltschachtel aus Karton, insbesondere für die Aufnahme von Medikamenten
DE7225796U (de) Musterpackung für Arzneimittel
DE1486764A1 (de) Hefter aus Kunststoffolie
DE4415346A1 (de) Nahtmaterialpackung
WO2012072491A1 (de) Spender zur aufbewahrung und bereitstellung eines stapels von jeweils einen wafer enthaltenden wafertaschen
DE8522974U1 (de) Blisterpackung
DE4415347A1 (de) Nahtmaterialpackung

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20100308

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA MK RS

DAX Request for extension of the european patent (deleted)
GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

Free format text: NOT ENGLISH

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 502008003512

Country of ref document: DE

Effective date: 20110622

RAP2 Party data changed (patent owner data changed or rights of a patent transferred)

Owner name: BAYER PHARMA AKTIENGESELLSCHAFT

REG Reference to a national code

Ref country code: ES

Ref legal event code: FG2A

Ref document number: 2364527

Country of ref document: ES

Kind code of ref document: T3

Effective date: 20110906

REG Reference to a national code

Ref country code: NL

Ref legal event code: VDEP

Effective date: 20110511

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110811

Ref country code: LT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110511

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110912

Ref country code: SE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110511

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110812

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110511

Ref country code: LV

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110511

Ref country code: SI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110511

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110511

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110911

REG Reference to a national code

Ref country code: IE

Ref legal event code: FD4D

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: NL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110511

Ref country code: MT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110511

BERE Be: lapsed

Owner name: BAYER SCHERING PHARMA A.G.

Effective date: 20110731

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: HR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110824

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110511

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110511

Ref country code: IE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110511

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110511

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110511

Ref country code: PL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110511

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110511

Ref country code: MC

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20110731

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

26N No opposition filed

Effective date: 20120214

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20110731

REG Reference to a national code

Ref country code: DE

Ref legal event code: R097

Ref document number: 502008003512

Country of ref document: DE

Effective date: 20120214

REG Reference to a national code

Ref country code: DE

Ref legal event code: R081

Ref document number: 502008003512

Country of ref document: DE

Owner name: BAYER INTELLECTUAL PROPERTY GMBH, DE

Free format text: FORMER OWNER: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT, 13353 BERLIN, DE

Effective date: 20120612

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20120731

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20120731

REG Reference to a national code

Ref country code: DE

Ref legal event code: R081

Ref document number: 502008003512

Country of ref document: DE

Owner name: BAYER INTELLECTUAL PROPERTY GMBH, DE

Free format text: FORMER OWNER: BAYER PHARMA AKTIENGESELLSCHAFT, 13353 BERLIN, DE

Effective date: 20130410

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20110729

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110811

REG Reference to a national code

Ref country code: ES

Ref legal event code: PC2A

Owner name: BAYER INTELLECTUAL PROPERTY GMBH

Effective date: 20130909

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: TR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110511

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: HU

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110511

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: ES

Payment date: 20130628

Year of fee payment: 6

Ref country code: DE

Payment date: 20130724

Year of fee payment: 6

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: HR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20110511

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FR

Payment date: 20130724

Year of fee payment: 6

Ref country code: GB

Payment date: 20130724

Year of fee payment: 6

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: IT

Payment date: 20130717

Year of fee payment: 6

REG Reference to a national code

Ref country code: AT

Ref legal event code: MM01

Ref document number: 508726

Country of ref document: AT

Kind code of ref document: T

Effective date: 20130729

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: AT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20130729

REG Reference to a national code

Ref country code: DE

Ref legal event code: R119

Ref document number: 502008003512

Country of ref document: DE

GBPC Gb: european patent ceased through non-payment of renewal fee

Effective date: 20140729

REG Reference to a national code

Ref country code: FR

Ref legal event code: ST

Effective date: 20150331

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20140729

Ref country code: DE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20150203

REG Reference to a national code

Ref country code: DE

Ref legal event code: R119

Ref document number: 502008003512

Country of ref document: DE

Effective date: 20150203

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: FR

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20140731

Ref country code: GB

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20140729

REG Reference to a national code

Ref country code: ES

Ref legal event code: FD2A

Effective date: 20151002

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: ES

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20140730

REG Reference to a national code

Ref country code: GB

Ref legal event code: 732E

Free format text: REGISTERED BETWEEN 20160901 AND 20160907