EP2109474A1 - Bouton poussoir d'injection - Google Patents

Bouton poussoir d'injection

Info

Publication number
EP2109474A1
EP2109474A1 EP08708028A EP08708028A EP2109474A1 EP 2109474 A1 EP2109474 A1 EP 2109474A1 EP 08708028 A EP08708028 A EP 08708028A EP 08708028 A EP08708028 A EP 08708028A EP 2109474 A1 EP2109474 A1 EP 2109474A1
Authority
EP
European Patent Office
Prior art keywords
push button
protrusion
driving part
bore
connection according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP08708028A
Other languages
German (de)
English (en)
Other versions
EP2109474B2 (fr
EP2109474B1 (fr
Inventor
Torben Stroem Hansen
Jakob Oest Wielandt
Lars Moerch Groth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38158028&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP2109474(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Priority to PL08708028T priority Critical patent/PL2109474T5/pl
Priority to EP08708028.9A priority patent/EP2109474B2/fr
Publication of EP2109474A1 publication Critical patent/EP2109474A1/fr
Application granted granted Critical
Publication of EP2109474B1 publication Critical patent/EP2109474B1/fr
Publication of EP2109474B2 publication Critical patent/EP2109474B2/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/3158Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button

Definitions

  • EP 1.003.581 discloses an injection device in which according to figure 15-16 a dose is set by rotating the scale drum out of the housing in a threaded connection.
  • a dose is set by rotating the scale drum out of the housing in a threaded connection.
  • the user pushes on the push button which forces the scale drum and the bushing to rotate together back into the housing.
  • the push button and the bushing rotates relatively to each other. The friction occurring between these relatively rotatable parts contributes to the force a user needs to apply in order to push back the bushing and the scale drum in order to inject the set dose.
  • the driving part 20 is provided with a protrusion 21 having a circular cross section and a top surface 22.
  • This protrusion 21 has at its proximal end a top part 23 with a decreased diameter compared to the remaining part 26 of the protrusion 21.
  • the protrusion 21 is provided with a radial extending rim 24 at its distal end. In the area around this rim 24, the protrusion 21 is provided with a belt 25 with a slightly raised diameter.

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Fuel-Injection Apparatus (AREA)
  • Push-Button Switches (AREA)
EP08708028.9A 2007-02-05 2008-01-21 Bouton poussoir d'injection Active EP2109474B2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PL08708028T PL2109474T5 (pl) 2007-02-05 2008-01-21 Przycisk iniekcyjny
EP08708028.9A EP2109474B2 (fr) 2007-02-05 2008-01-21 Bouton poussoir d'injection

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07101729 2007-02-05
EP08708028.9A EP2109474B2 (fr) 2007-02-05 2008-01-21 Bouton poussoir d'injection
PCT/EP2008/050624 WO2008095762A1 (fr) 2007-02-05 2008-01-21 Bouton poussoir d'injection

Publications (3)

Publication Number Publication Date
EP2109474A1 true EP2109474A1 (fr) 2009-10-21
EP2109474B1 EP2109474B1 (fr) 2010-10-06
EP2109474B2 EP2109474B2 (fr) 2019-01-30

Family

ID=38158028

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08708028.9A Active EP2109474B2 (fr) 2007-02-05 2008-01-21 Bouton poussoir d'injection

Country Status (14)

Country Link
US (1) US9265893B2 (fr)
EP (1) EP2109474B2 (fr)
JP (1) JP5634068B2 (fr)
CN (1) CN101605569B (fr)
AT (1) ATE483487T1 (fr)
AU (1) AU2008213084B2 (fr)
BR (1) BRPI0806854B8 (fr)
CA (1) CA2676810C (fr)
DE (1) DE602008002896D1 (fr)
DK (1) DK2109474T4 (fr)
ES (1) ES2351778T5 (fr)
PL (1) PL2109474T5 (fr)
RU (1) RU2462275C2 (fr)
WO (1) WO2008095762A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11577029B2 (en) 2012-03-15 2023-02-14 Becton, Dickinson And Company Multiple use disposable injection pen

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2314182T3 (es) 2002-02-11 2009-03-16 Antares Pharma, Inc. Inyector intradermico.
FI1850892T4 (fi) 2005-01-24 2023-08-31 Neula-avusteinen esitäytetyn ruiskun omaava suihkuinjektori
WO2007131025A1 (fr) 2006-05-03 2007-11-15 Antares Pharma, Inc. Injecteur à dosage réglable
US8251947B2 (en) 2006-05-03 2012-08-28 Antares Pharma, Inc. Two-stage reconstituting injector
ES2548447T3 (es) 2008-03-10 2015-10-16 Antares Pharma, Inc. Dispositivo de seguridad para inyector
JP5611208B2 (ja) 2008-08-05 2014-10-22 アンタレス・ファーマ・インコーポレーテッド 多数回服用量の注射装置
EP2408493B1 (fr) 2009-03-20 2024-07-24 Antares Pharma, Inc. Système d'injection d'agents dangereux
ES2749395T3 (es) 2009-11-20 2020-03-20 Becton Dickinson Co Dispositivo de inyección sin necesidad de un engranaje
CA3207394A1 (fr) 2011-03-16 2012-09-20 Becton, Dickinson And Company Crayon d'injection multi-usage jetable
US8496619B2 (en) 2011-07-15 2013-07-30 Antares Pharma, Inc. Injection device with cammed ram assembly
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
PT2822618T (pt) 2012-03-06 2024-03-04 Antares Pharma Inc Seringa pré-cheia com característica de força de rutura
KR20150011346A (ko) 2012-04-06 2015-01-30 안타레스 팔마, 인코퍼레이티드 테스토스테론 조성물의 바늘-보조식 젯 주입 투여 장치 및 방법
WO2013155153A1 (fr) * 2012-04-13 2013-10-17 Becton, Dickinson And Company Microperfuseur à rétraction automatique de l'aiguille
US9364610B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Injection device with cammed ram assembly
PT3659647T (pt) 2013-02-11 2024-03-27 Antares Pharma Inc Dispositivo de injeção a jato auxiliado por agulha tendo força de gatilho reduzida
CA2905031C (fr) 2013-03-11 2018-01-23 Hans PFLAUMER Injecteur de dose avec systeme a pignon
WO2014165136A1 (fr) 2013-03-12 2014-10-09 Antares Pharma, Inc. Seringues pré-remplies à volume constant et leurs trousses
CN106132460B (zh) 2014-03-25 2019-10-29 沃克哈特有限公司 具有最终剂量停止和改进的剂量设定特征的流体输送笔
MA41906A (fr) 2015-04-10 2018-02-13 Dompe Farm Spa Dispositif de distribution de gouttes oculaires
JP7181085B2 (ja) 2016-03-09 2022-11-30 ジャイラス エーシーエムアイ インク ディー/ビー/エー オリンパス サージカル テクノロジーズ アメリカ 内視鏡器具
DE102016207722A1 (de) * 2016-05-04 2017-11-30 Aptar Radolfzell Gmbh Flüssigkeitsspender
ITUA20162072A1 (it) * 2016-06-30 2017-12-30 Platinum Corp Srl Dropper a volume controllato
US10688247B2 (en) 2017-07-13 2020-06-23 Haselmeier Ag Injection device with flexible dose selection
US11969583B2 (en) 2018-07-17 2024-04-30 Medmix Switzerland Ag Injection device with dose interruption fail safe
JP7217244B2 (ja) 2020-02-18 2023-02-02 ジャイラス エーシーエムアイ インク ディー/ビー/エー オリンパス サージカル テクノロジーズ アメリカ 内視鏡器具

Family Cites Families (159)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2444570A (en) 1948-07-06 Drive for counter numeral wheels
GB735443A (en) 1952-09-02 1955-08-24 English Numbering Machines Improvements in or relating to counting devices
BE639963A (fr) 1963-05-02
CH499734A (de) 1968-07-19 1970-11-30 Kienzle Apparate Gmbh Klinkengesperre als Einrichtungs- und Überholkupplung
GB2109690B (en) 1981-02-12 1985-02-20 Robert Charles Turner Dose metering plunger devices for use with syringes
US4568335A (en) 1981-08-28 1986-02-04 Markwell Medical Institute, Inc. Device for the controlled infusion of medications
DE3204178C2 (de) 1982-02-06 1986-03-20 Eppendorf Gerätebau Netheler + Hinz GmbH, 2000 Hamburg Pipettiervorrichtung
GB2141799B (en) 1983-06-03 1986-07-16 Diehl Gmbh & Co An adjusting ratchet mechanism for a time switch
DE3468173D1 (en) 1983-09-07 1988-02-04 Disetronic Ag Portable infusion apparatus
US4592745A (en) 1984-02-29 1986-06-03 Novo Industri A/S Dispenser
FR2583291A1 (fr) 1985-06-14 1986-12-19 Hazon Bernard Dispositif d'avancement pas a pas du piston de seringues par double vis coaxiale avec controle du debit d'injection. application aux injections medicamenteuses intra-dermiques repetitives
DE3670768D1 (de) 1985-11-08 1990-06-07 Disetronic Ag Injektionsgeraet.
DE3609555A1 (de) 1986-03-21 1987-09-24 Josef Porner Blutentnahmespritze
US5716990A (en) 1987-03-09 1998-02-10 Cancer Research Campaign Technology Limited Drug delivery systems
DK177187A (da) 1987-04-07 1988-10-08 Dcp Af 1988 As Doseringsenhed til dosering af et antal afmaalte maengder af en vaeske, saasom insulin, fra en glasampul
DE3715258C2 (de) 1987-05-08 1996-10-31 Haselmeier Wilhelm Fa Injektionsgerät
GB8713810D0 (en) 1987-06-12 1987-07-15 Hypoguard Uk Ltd Measured dose dispensing device
US4919596A (en) 1987-12-04 1990-04-24 Pacesetter Infusion, Ltd. Fluid delivery control and monitoring apparatus for a medication infusion system
US4833379A (en) 1988-01-13 1989-05-23 Sherwood Medical Company Motor control fail-safe circuit
CH675078A5 (fr) 1988-01-22 1990-08-31 Nosta Ag
US4973318A (en) 1988-02-10 1990-11-27 D.C.P. Af 1988 A/S Disposable syringe
DK166948B1 (da) 1988-02-10 1993-08-09 Dcp Af 1988 As Doseringsenhed til dosering af et antal afmaalte maengder af en vaeske, saasom insulin, fra en glastubule
DE58908873D1 (de) 1988-09-12 1995-02-23 Graesslin Kg Richtgesperre für eine Schaltuhr.
DK68789A (da) 1989-02-14 1990-08-15 Novo Nordisk As Injektionspen
US4994033A (en) 1989-05-25 1991-02-19 Schneider (Usa) Inc. Intravascular drug delivery dilatation catheter
US5226895A (en) 1989-06-05 1993-07-13 Eli Lilly And Company Multiple dose injection pen
DK17890A (da) 1990-01-22 1991-07-23 Novo Nordisk As Fremgangsmaade og apparat til opblanding og injicering af et laegemiddel
GB9007113D0 (en) 1990-03-29 1990-05-30 Sams Bernard Dispensing device
US5207752A (en) 1990-03-30 1993-05-04 Alza Corporation Iontophoretic drug delivery system with two-stage delivery profile
US5492534A (en) 1990-04-02 1996-02-20 Pharmetrix Corporation Controlled release portable pump
US5318540A (en) 1990-04-02 1994-06-07 Pharmetrix Corporation Controlled release infusion device
US5226896A (en) 1990-04-04 1993-07-13 Eli Lilly And Company Dose indicating injection pen
IT220491Z2 (it) 1990-04-13 1993-09-24 Stilolinea Srl Penna a sfera del tipo a punta scrivente rientrante
US5257987A (en) 1990-05-21 1993-11-02 Pharmetrix Corporation Controlled release osmotic infusion system
CN2070927U (zh) * 1990-07-12 1991-02-06 上海无线电器厂 新型旋转轴柄器件旋钮
JP3042710B2 (ja) 1990-09-21 2000-05-22 ノボ ノルディスク アクティーゼルスカブ ペンシリンジアセンブリー
US5284480A (en) 1990-11-09 1994-02-08 Medtronic, Inc. Inflation/deflation syringe with threaded plunger
GB9026191D0 (en) 1990-12-01 1991-01-16 Harris Pharma Ltd Breath actuated dispensing device
US5331954A (en) 1990-12-21 1994-07-26 Novo Nordisk A/S Device for nasal delivery of liquid medications
EP0498737B1 (fr) 1991-02-07 1995-07-19 Terumo Kabushiki Kaisha Dispositif de dosage pour injecteur
DE4112259A1 (de) 1991-04-15 1992-10-22 Medico Dev Investment Co Injektionsgeraet
DK68991D0 (da) 1991-04-17 1991-04-17 Novo Nordisk As Manifold
US5645052A (en) 1991-04-26 1997-07-08 The Boc Group Plc Anaesthetic vaporizer with expandable/contractable reservoir for pumping liquid anaesthetic
EP0525525B1 (fr) 1991-07-24 1995-05-03 Medico Development Investment Company Injecteur
DK175491D0 (da) 1991-10-18 1991-10-18 Novo Nordisk As Apparat
US5611783A (en) 1991-11-29 1997-03-18 Novo Nordisk A/S Pen-shaped syringe
DK194291D0 (da) 1991-11-29 1991-11-29 Novo Nordisk As Sproejte til automatisk injektion.
US5246417A (en) 1991-12-11 1993-09-21 Alza Corporation Indicator for iontophoresis system
US5279585A (en) 1992-02-04 1994-01-18 Becton, Dickinson And Company Medication delivery pen having improved dose delivery features
CH682968B5 (fr) * 1992-02-12 1994-06-30 Rolex Montres Procédé de fabrication d'un joint et joint pour dispositif de commande étanche pour montre obtenu selon ce procédé.
CH682806A5 (de) 1992-02-21 1993-11-30 Medimpex Ets Injektionsgerät.
EP0632734B1 (fr) 1992-03-25 1998-06-10 Tebro S.A. Distributeur a jet de poudre pour traitements par inhalation de medicament
US5271527A (en) 1992-04-02 1993-12-21 Habley Medical Technology Corporation Reusable pharmaceutical dispenser with full stroke indicator
US5281198A (en) 1992-05-04 1994-01-25 Habley Medical Technology Corporation Pharmaceutical component-mixing delivery assembly
UA26190C2 (uk) 1992-07-28 1999-07-19 Сейфтек Ай Лімітед Шприц
GB9219849D0 (en) 1992-09-19 1992-10-28 Hypoguard Uk Ltd Device
ES2154651T3 (es) 1992-10-15 2001-04-16 Gen Hospital Corp Bomba de infusion con biblioteca de medicamentos cargable electronicamente.
US5545147A (en) 1992-10-20 1996-08-13 Eli Lilly And Company Anti-backup improvement for hypodermic syringes
US5320609A (en) 1992-12-07 1994-06-14 Habley Medical Technology Corporation Automatic pharmaceutical dispensing syringe
GB9226423D0 (en) 1992-12-18 1993-02-10 Sams Bernard Incrementing mechanisms
CZ284900B6 (cs) 1993-02-19 1999-04-14 Medicorp Holding S.A. Předem naplněná stříkačka pro uložení a vydávání kapalné a sterilní léčebné látky
US5383865A (en) 1993-03-15 1995-01-24 Eli Lilly And Company Medication dispensing device
US5584815A (en) 1993-04-02 1996-12-17 Eli Lilly And Company Multi-cartridge medication injection device
ZA941881B (en) 1993-04-02 1995-09-18 Lilly Co Eli Manifold medication injection apparatus and method
SE9301494D0 (sv) 1993-04-30 1993-04-30 Kabi Pharmacia Ab A device for dosing liquid preparation
US5478316A (en) 1994-02-02 1995-12-26 Becton, Dickinson And Company Automatic self-injection device
US5562623A (en) 1994-02-14 1996-10-08 Univec Single-use syringe assembly including spring clip lock and plunger
AU1595395A (en) 1994-06-15 1996-01-05 Interventional Research Technologies, Inc. Locking device for syringe or like instrument
US5827232A (en) 1994-06-22 1998-10-27 Becton Dickinson And Company Quick connect medication delivery pen
US5725508A (en) 1994-06-22 1998-03-10 Becton Dickinson And Company Quick connect medication delivery pen
US5440976A (en) 1994-08-23 1995-08-15 Fred Giuliano Adjustable dispensing stirrer for soluble sweeteners
CA2186869A1 (fr) 1994-08-24 1996-02-29 Hideto Yamagata Appareil pour injections
US5549574A (en) 1994-08-30 1996-08-27 Eli Lilly And Company Cartridge assembly for use in a pen-type medicament injector
US5549575A (en) 1994-09-13 1996-08-27 Becton Dickinson And Company Cartridge retainer assembly for medication delivery pen
US5582598A (en) 1994-09-19 1996-12-10 Becton Dickinson And Company Medication delivery pen with variable increment dose scale
BR9508847A (pt) 1994-09-20 1999-11-30 Novo Nordisk A S E Slagterisel Processo para tratar uma solução aquosa de proteìna e para produzir um gênero alimentìcio à base de carne, mistura de solução de proteìna/hidrolisado tratada com calor, ou hidrolisado lìquido tratado com calor, gênero alimentìcio à base de carne e uso da mistura de solução de proteìna/hidrolisado tratada com calor, ou de hidrolisado lìquido tratado com calor
ZA958073B (en) 1994-09-28 1996-04-23 Anthony William Manicom Method of and apparatus for administering a drug to a patient
GB9503969D0 (en) 1995-02-28 1995-04-19 Sams Bernard Incrementing mechanism
CA2213682C (fr) 1995-03-07 2009-10-06 Eli Lilly And Company Distributeur recyclable de medicament
DK0840628T3 (da) 1995-06-02 2002-10-07 Novo Nordisk As Automatisk tilbagetrækning af stempelstang
US5674204A (en) 1995-09-19 1997-10-07 Becton Dickinson And Company Medication delivery pen cap actuated dose delivery clutch
US5688251A (en) 1995-09-19 1997-11-18 Becton Dickinson And Company Cartridge loading and priming mechanism for a pen injector
US5899879A (en) 1995-12-19 1999-05-04 Genesis Medical Technologies, Inc. Spring-actuated needleless injector
PL185539B1 (pl) 1996-02-23 2003-05-30 Novo Nordisk As Strzykawka z mechanizmem ustalania dawek i elektronicznym przedstawianiem parametrów
US6277098B1 (en) 1996-03-12 2001-08-21 Novo Nordisk A/S Injection device with electronic presentation of set doses
DE59609513D1 (de) 1996-04-02 2002-09-05 Disetronic Licensing Ag Injektionsgerät
CA2252620A1 (fr) 1996-04-24 1997-10-30 Novo Nordisk A/S Aiguille pour injection
HUP9904152A3 (en) 1996-07-05 2000-05-29 Novo Nordisk As Flexible piston rod
WO1998001170A1 (fr) 1996-07-05 1998-01-15 Novo Nordisk A/S Mecanisme d'insertion automatique d'aiguille
CA2258308A1 (fr) 1996-07-05 1998-01-15 Novo Nordisk A/S Dispositif de dosage
US5709662A (en) 1996-08-23 1998-01-20 Becton Dickinson France, S.A. Cartridge for an injection device
US5843036A (en) 1996-08-23 1998-12-01 Becton Dickinson And Company Non-dosing cartridge for an injection device
US6110149A (en) 1996-09-13 2000-08-29 Novo Nordisk A/S Syringe
JP3989966B2 (ja) 1996-09-13 2007-10-10 ノボ ノルディスク アクティーゼルスカブ 注入式注射器用投薬量ディスプレイ
US5947934A (en) 1996-09-13 1999-09-07 Novo Nordisk A/S Dose display for an injection syringe
US6379339B1 (en) 1996-09-13 2002-04-30 Nova Nordisk A/S Syringe
EP0927055B1 (fr) 1996-09-20 2001-12-05 Novo Nordisk A/S Cylindre de travail
US6146361A (en) 1996-09-26 2000-11-14 Becton Dickinson And Company Medication delivery pen having a 31 gauge needle
SE9604162D0 (sv) * 1996-11-13 1996-11-13 Astra Ab Membrane
US5954689A (en) 1996-12-20 1999-09-21 Novo Nordisk A/S Jet injector
GB2321419B (en) 1997-01-27 2001-02-07 Medic Aid Ltd Atomizer
WO1998033538A1 (fr) 1997-02-04 1998-08-06 Novo Nordisk A/S Dispositif pour l'administration d'une suspension medicamenteuse liquide
DE29703820U1 (de) 1997-03-03 1998-07-02 Medico Development Investment Co., Ascona Injektionsgerät
US5898028A (en) 1997-03-20 1999-04-27 Novo Nordisk A/S Method for producing powder formulation comprising an insulin
US6277097B1 (en) 1997-03-25 2001-08-21 Novo Nordisk A/S Injection system
RU2111019C1 (ru) 1997-05-22 1998-05-20 Сергей Александрович Хворостов Универсальный инъектор
US6074372A (en) 1997-06-09 2000-06-13 Novo Nordisk A/S Dose setting mechanism and an injection syringe having such a dose setting mechanism
US6003736A (en) 1997-06-09 1999-12-21 Novo Nordisk A/S Device for controlled dispensing of a dose of a liquid contained in a cartridge
US5961496A (en) 1997-06-17 1999-10-05 Novo Nordisk A/S Syringe with tiltable nut for quick piston disengagement
US6796970B1 (en) 1997-06-17 2004-09-28 Novo Nordisk A/S Dose setting device
WO1999002210A1 (fr) 1997-07-11 1999-01-21 Novo Nordisk A/S Dispositif d'enregistrement du reglage d'un dispositif medical
JP2003514586A (ja) 1997-07-14 2003-04-22 ノボ ノルディスク アクティーゼルスカブ 円筒状アンプル
WO1999003521A1 (fr) 1997-07-14 1999-01-28 Novo Nordisk A/S Element d'injection
DE19730999C1 (de) 1997-07-18 1998-12-10 Disetronic Licensing Ag Dosierknopfsicherung an einer Vorrichtung zur dosierten Verabreichung eines injizierbaren Produkts
US5957896A (en) 1997-08-11 1999-09-28 Becton, Dickinson And Company Medication delivery pen
FR2767479B1 (fr) 1997-08-22 1999-10-22 Aguettant Lab Dispositif d'injection de medicament
AU9202398A (en) 1997-09-29 1999-04-23 Becton Dickinson & Company Injection device and drug cartridge for preventing cross-use of the device and drug cartridge
US6312413B1 (en) 1997-10-30 2001-11-06 Novo Nordisk A/S Cylinder ampoule
ES2153711T3 (es) 1998-01-30 2001-03-01 Novo Nordisk As Jeringuilla de inyeccion.
US6770288B2 (en) 1998-02-13 2004-08-03 Pfizer Products Inc. Drug delivery system
US5961495A (en) 1998-02-20 1999-10-05 Becton, Dickinson And Company Medication delivery pen having a priming mechanism
US6221053B1 (en) 1998-02-20 2001-04-24 Becton, Dickinson And Company Multi-featured medication delivery pen
US6248095B1 (en) 1998-02-23 2001-06-19 Becton, Dickinson And Company Low-cost medication delivery pen
AU4435399A (en) 1998-06-11 1999-12-30 Cerus Corporation Inhibiting proliferation of arterial smooth muscle cells
AU4769599A (en) 1998-07-08 2000-02-01 Novo Nordisk A/S A medical delivery device and a cartridge assembly for use in the same
US6033376A (en) 1998-09-30 2000-03-07 Allergan Sales, Inc. Wound shaper sleeve
US6605067B1 (en) 1998-11-20 2003-08-12 Novo Nordisk A/S Injection needle
US6258062B1 (en) 1999-02-25 2001-07-10 Joseph M. Thielen Enclosed container power supply for a needleless injector
TW453884B (en) 1999-09-16 2001-09-11 Novo Nordisk As Dose setting limiter
US6514230B1 (en) 1999-10-12 2003-02-04 Novo Nordisk A/S Air shot mechanism for electronic injection devices
GB0007071D0 (en) 2000-03-24 2000-05-17 Sams Bernard One-way clutch mechanisms and injector devices
US6692472B2 (en) 2000-05-04 2004-02-17 Novo Nordisk A/S Injection device, a preassembled dose setting and injection mechanism for an injection device, and a method of assembling an injection device
US6547763B2 (en) 2000-05-18 2003-04-15 Novo Nordisk A/S Dose display for injection device
US6716198B2 (en) 2000-05-18 2004-04-06 Novo Nordisk A/S Injection device
US6547764B2 (en) 2000-05-31 2003-04-15 Novo Nordisk A/S Double pointed injection needle
US6663602B2 (en) 2000-06-16 2003-12-16 Novo Nordisk A/S Injection device
ATE386563T1 (de) 2000-07-14 2008-03-15 Novo Nordisk As Flüssigkeitsabgabevorrichtung und verfahren zum vermindern des tröpfelns
WO2002024257A1 (fr) 2000-09-22 2002-03-28 Novo Nordisk A/S Dispositif pour l'apport d'un medicament
US6899699B2 (en) 2001-01-05 2005-05-31 Novo Nordisk A/S Automatic injection device with reset feature
EP1361908B1 (fr) 2001-02-14 2007-12-19 Novo Nordisk A/S Dispositif d'injection ou d'injection commande electroniquement
EP1776975B1 (fr) 2001-05-16 2011-06-22 Eli Lilly & Company Appareil injecteur de médication avec ensemble d'entraînement qui facilite le réarmement
GB0113881D0 (en) 2001-06-07 2001-08-01 Innovate Biomed Ltd Foil cutting system
DE10163326A1 (de) 2001-07-30 2003-02-27 Disetronic Licensing Ag Verabreichungsgerät mit Dosiervorrichtung
US6941948B2 (en) 2002-03-07 2005-09-13 Vectura Drug Delivery Medicament storage and delivery devices
US6945961B2 (en) 2002-07-10 2005-09-20 Novo Nordisk A/S Injection device
EP1521607A1 (fr) 2002-07-10 2005-04-13 Novo Nordisk A/S Dispositif d'injection a limiteur de dosage
EP1391794A1 (fr) 2002-07-23 2004-02-25 Novo Nordisk A/S Dispositif muni d'indicateur de temps
ATE331542T1 (de) 2002-08-29 2006-07-15 Novo Nordisk As Injektionsvorrichtung mit frontladung
CA2500195C (fr) 2002-09-24 2009-07-21 Shl Medical Ab Dispositif d'injection
WO2004066939A2 (fr) 2003-01-27 2004-08-12 Sarnoff Corporation Systeme d'administration de medicament a liberation controlee
GB0304823D0 (en) 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
GB0304822D0 (en) 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
GB0304824D0 (en) 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
GB0306642D0 (en) 2003-03-22 2003-04-30 Dca Design Int Ltd Improvements in and relating to an injector for a medical product
GB0308267D0 (en) 2003-04-10 2003-05-14 Dca Design Int Ltd Improvements in and relating to a pen-type injector
SI1656170T1 (sl) 2003-08-12 2019-05-31 Eli Lilly And Company Oprema za izdajanje zdravil s trojnim vijačnim navojem za mehanski pospešek
US7448385B2 (en) 2004-06-07 2008-11-11 Purepharm Inc. Nasal adaptation of an oral inhaler device
FR2882917B1 (fr) * 2005-03-14 2008-07-04 Micro Mega Int Mfg Sa "dispositif d'accrochage d'un intrument dentaire sur une piece a main forme d'un ensemble axe tournant, ressort d'accrochage et bouton poussoir"
JP4325699B2 (ja) * 2007-04-26 2009-09-02 株式会社デンソー 操作つまみ

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2008095762A1 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11577029B2 (en) 2012-03-15 2023-02-14 Becton, Dickinson And Company Multiple use disposable injection pen

Also Published As

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ES2351778T3 (es) 2011-02-10
CA2676810C (fr) 2016-06-21
CA2676810A1 (fr) 2008-08-14
JP2010517650A (ja) 2010-05-27
DK2109474T4 (da) 2019-05-13
WO2008095762A1 (fr) 2008-08-14
DK2109474T3 (da) 2011-01-31
RU2462275C2 (ru) 2012-09-27
PL2109474T3 (pl) 2011-04-29
CN101605569B (zh) 2012-09-05
ES2351778T5 (es) 2019-07-09
RU2009132183A (ru) 2011-03-20
BRPI0806854A2 (pt) 2014-04-29
AU2008213084B2 (en) 2013-03-28
CN101605569A (zh) 2009-12-16
EP2109474B2 (fr) 2019-01-30
PL2109474T5 (pl) 2019-07-31
US20100145282A1 (en) 2010-06-10
AU2008213084A1 (en) 2008-08-14
JP5634068B2 (ja) 2014-12-03
EP2109474B1 (fr) 2010-10-06
DE602008002896D1 (de) 2010-11-18
US9265893B2 (en) 2016-02-23
BRPI0806854B1 (pt) 2018-08-14
ATE483487T1 (de) 2010-10-15
BRPI0806854B8 (pt) 2021-06-22

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