EP2089366A2 - Pyrrazol-3-on- und/oder pyridazin-3-onderivate als inhibitoren der lysyloxidase - Google Patents
Pyrrazol-3-on- und/oder pyridazin-3-onderivate als inhibitoren der lysyloxidaseInfo
- Publication number
- EP2089366A2 EP2089366A2 EP05818002A EP05818002A EP2089366A2 EP 2089366 A2 EP2089366 A2 EP 2089366A2 EP 05818002 A EP05818002 A EP 05818002A EP 05818002 A EP05818002 A EP 05818002A EP 2089366 A2 EP2089366 A2 EP 2089366A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- turbocharger
- passage
- insert
- housing according
- main body
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- AAILEWXSEQLMNI-UHFFFAOYSA-N 1h-pyridazin-6-one Chemical class OC1=CC=CN=N1 AAILEWXSEQLMNI-UHFFFAOYSA-N 0.000 title 1
- 102000004669 Protein-Lysine 6-Oxidase Human genes 0.000 title 1
- 108010003894 Protein-Lysine 6-Oxidase Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- JEXVQSWXXUJEMA-UHFFFAOYSA-N pyrazol-3-one Chemical compound O=C1C=CN=N1 JEXVQSWXXUJEMA-UHFFFAOYSA-N 0.000 title 1
- 239000012530 fluid Substances 0.000 claims abstract 5
- 238000007789 sealing Methods 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Supercharger (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004056226A DE102004056226A1 (de) | 2004-11-22 | 2004-11-22 | Neuartige Inhibitoren der Lysyloxidase |
| PCT/DE2005/002086 WO2006053555A2 (de) | 2004-11-22 | 2005-11-20 | Pyrraz0l-3-on- und/oder pyridazin-3-onderivate als inhibitoren der lysyloxidase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EP2089366A2 true EP2089366A2 (de) | 2009-08-19 |
Family
ID=36177758
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP05818002A Withdrawn EP2089366A2 (de) | 2004-11-22 | 2005-11-20 | Pyrrazol-3-on- und/oder pyridazin-3-onderivate als inhibitoren der lysyloxidase |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP2089366A2 (de) |
| DE (2) | DE102004056226A1 (de) |
| WO (1) | WO2006053555A2 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6800872B2 (ja) | 2015-03-06 | 2020-12-16 | ファーマケア,インク. | リシルオキシダーゼ様2阻害剤とその使用 |
| ES2838977T3 (es) | 2015-03-06 | 2021-07-02 | Pharmakea Inc | Inhibidores de la lisil oxidasa fluorada tipo 2 y usos de los mismos |
| EP3317258A4 (de) * | 2015-07-01 | 2019-06-26 | Pharmakea, Inc. | Lysyloxidase-like-2-inhibitoren und verwendungen davon |
| AU2017218889A1 (en) | 2016-02-09 | 2018-08-30 | Pharmakea, Inc. | Quinolinone lysyl oxidase-like 2 inhibitors and uses thereof |
| GB201602934D0 (en) | 2016-02-19 | 2016-04-06 | Cancer Res Inst Royal | Compounds |
| US10774069B2 (en) | 2016-09-07 | 2020-09-15 | Pharmakea, Inc. | Crystalline forms of a lysyl oxidase-like 2 inhibitor and methods of making |
| MX2019002612A (es) | 2016-09-07 | 2019-08-21 | Pharmakea Inc | Usos de un inhibidor de lisil-oxidasa tipo 2. |
| GB201809295D0 (en) | 2018-06-06 | 2018-07-25 | Institute Of Cancer Res Royal Cancer Hospital | Lox inhibitors |
| CN112533897B (zh) | 2018-08-03 | 2023-07-14 | 法玛西斯有限公司 | 赖氨酰氧化酶的卤代烯丙胺砜衍生抑制剂及其用途 |
| GB201818750D0 (en) | 2018-11-16 | 2019-01-02 | Institute Of Cancer Res Royal Cancer Hospital | Lox inhibitors |
| US12018015B2 (en) | 2021-06-18 | 2024-06-25 | Aligos Therapeutics, Inc. | Methods and compositions for targeting PD-L1 |
| KR20240121760A (ko) | 2021-12-16 | 2024-08-09 | 알리고스 테라퓨틱스 인코포레이티드 | Pd-l1을 표적화하기 위한 방법 및 조성물 |
| US12233056B2 (en) | 2022-04-06 | 2025-02-25 | Syntara Limited | Lysyl oxidase inhibitors for treating myeloid malignancies |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5328913A (en) * | 1992-12-11 | 1994-07-12 | Duke University | Minoxidil analogs as inhibitors of cell proliferation and lysyl hydroxylase |
| US6469003B1 (en) * | 1998-08-14 | 2002-10-22 | Nihon Nohyaku Co., Ltd. | Pyridazinone derivatives |
| DE10216144A1 (de) * | 2002-04-12 | 2003-11-06 | Bayer Ag | Substituierte 2-Phenyl-3(2H)-Pyridazinone |
-
2004
- 2004-11-22 DE DE102004056226A patent/DE102004056226A1/de not_active Withdrawn
-
2005
- 2005-11-20 WO PCT/DE2005/002086 patent/WO2006053555A2/de not_active Ceased
- 2005-11-20 EP EP05818002A patent/EP2089366A2/de not_active Withdrawn
- 2005-11-20 DE DE112005003431T patent/DE112005003431A5/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| DE102004056226A1 (de) | 2006-05-24 |
| WO2006053555A2 (de) | 2006-05-26 |
| DE112005003431A5 (de) | 2007-10-31 |
| WO2006053555A3 (de) | 2006-07-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP1766195A1 (de) | Turboladergehäuse, turbolader und multiturboladersystem | |
| EP2089366A2 (de) | Pyrrazol-3-on- und/oder pyridazin-3-onderivate als inhibitoren der lysyloxidase | |
| CN101983282B (zh) | 涡轮增压器 | |
| CA1326476C (en) | Gas compressor having dry gas seals for balancing end thrust | |
| US10240610B2 (en) | Turbocharger purge seal including axisymmetric supply cavity | |
| ATE467748T1 (de) | Axialschublager für mehrstufige zentrifugalpumpe | |
| CA2352021C (en) | Turbocharger shaft dual phase seal | |
| US20150049967A1 (en) | Systems and methods for protecting a turbocharger aluminum bearing housing | |
| EP1193372A3 (de) | Lager und Dichtungsvorrichtung sowie deren Montage | |
| CN105980687B (zh) | 包括衬里轴承表面的推力轴承组件 | |
| US7789636B2 (en) | Turbomachine, particularly exhaust gas turbocharger | |
| CN106050332B (zh) | 涡轮增压器轴承组件 | |
| IT201600120314A1 (it) | Turbo-compressore e metodo di funzionamento di un turbo-compressore | |
| US11022130B2 (en) | Turbocharger | |
| US10443439B2 (en) | Bearing structure and turbocharger | |
| CN112780584B (zh) | 磁悬浮压缩机 | |
| EP3263911A1 (de) | Kompressorgehäuse für einen turbolader und herstellungsverfahren dafür | |
| JP2008518158A (ja) | ロータ軸用の軸取り付け部を備えたターボ過給機ユニット | |
| AU2006224213A8 (en) | An impeller for a centrifugal pump | |
| US10662965B2 (en) | Sealing structure and turbocharger | |
| CN116745548A (zh) | 具有减少的工艺气体消耗的压缩机装置 | |
| CN102245904A (zh) | 可减小的卸载孔 | |
| GB2493737A (en) | Turbo-machine automatic thrust balancing | |
| JPH0968194A (ja) | キャンドモータポンプ | |
| JP2013245662A (ja) | 過給機 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| 17P | Request for examination filed |
Effective date: 20070622 |
|
| AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR |
|
| AX | Request for extension of the european patent |
Extension state: AL BA HR MK YU |
|
| RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: BURCHARDT, ELMAR REINHOLD, DR. DR. |
|
| 17Q | First examination report despatched |
Effective date: 20110608 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 20110601 |