EP1743701B1 - Pipette à piston - Google Patents
Pipette à piston Download PDFInfo
- Publication number
- EP1743701B1 EP1743701B1 EP06010457A EP06010457A EP1743701B1 EP 1743701 B1 EP1743701 B1 EP 1743701B1 EP 06010457 A EP06010457 A EP 06010457A EP 06010457 A EP06010457 A EP 06010457A EP 1743701 B1 EP1743701 B1 EP 1743701B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- holder
- pipette
- pipette according
- stopper
- equipment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000011324 bead Substances 0.000 claims description 4
- 244000208734 Pisonia aculeata Species 0.000 claims 2
- 239000007788 liquid Substances 0.000 description 22
- 241000047428 Halter Species 0.000 description 9
- 230000005540 biological transmission Effects 0.000 description 4
- 230000008878 coupling Effects 0.000 description 4
- 238000010168 coupling process Methods 0.000 description 4
- 238000005859 coupling reaction Methods 0.000 description 4
- 230000008859 change Effects 0.000 description 3
- 230000009471 action Effects 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 230000008901 benefit Effects 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 230000000881 depressing effect Effects 0.000 description 1
- 238000011038 discontinuous diafiltration by volume reduction Methods 0.000 description 1
- 239000012154 double-distilled water Substances 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Images
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
- B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
- B01L3/0224—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type having mechanical means to set stroke length, e.g. movable stops
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/148—Specific details about calibrations
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/02—Identification, exchange or storage of information
- B01L2300/025—Displaying results or values with integrated means
- B01L2300/026—Drum counters
Definitions
- the invention relates to a piston stroke pipette for exchangeable pipette tips.
- Piston lifting pipettes are used for dosing liquids. They take up a certain volume of sample liquid in a pipette tip.
- the pipette tip is usually made of plastic as a disposable item. After dosing, the pipette tip is interchangeable with a fresh pipette tip. In this way, contamination of the piston stroke pipette and carryover of sample liquid is avoided.
- the piston stroke pipette has a cylinder with a piston displaceable therein.
- the cylinder is connected via a connection channel to openings in a seat for releasably attaching a pipette tip.
- the piston is coupled to a drive device which serves to displace the piston in the cylinder.
- the piston is displaceable between an upper and a lower stop in the cylinder.
- the piston moves an air column, thereby drawing liquid into and out of the pipette tip.
- the counter-stop is at the lower stop.
- At the beginning of the displacement of air from the cylinder of the counter-attack is at the top stop. The amount of liquid taken or dispensed depends on the stroke of the piston.
- the stroke volume of the piston does not exactly correspond to the amount of liquid taken in and dispensed. Since the air column lengthens slightly under the weight of the liquid, the stroke volume exceeds the liquid volume. The deviation of stroke volume and liquid volume depends in particular on the density and viscosity of the liquid, the temperature, the air pressure and wetting effects. To calibrate Kolbenhubpipetten to a specific metering volume, it is known to adjust the position of the upper stop, for example WO 03/033151 or US-A-3827305 ,
- a fixed volume pipette with an upper stop in the form of an adjustable by means of a calibration tool threaded sleeve is made of US 4,020,698 known.
- the sleeve-like calibration part has a scale on the outside, which is visible from outside through a transparent reading window in the pipette housing.
- a factory calibration is made by the pipette manufacturer under standard conditions.
- the dosing liquid used is bidistilled water at a temperature of 20 to 25 ° C and an air pressure of 1013 mbar. If the user wants to pipette under different conditions (for example, another liquid such as double-distilled water), he must change the factory calibration. The change in the factory calibration usually requires extensive use of tools. Finding the factory calibration requires elaborate gravimetric measurements.
- the object of the invention is to provide a piston stroke pipette which facilitates the user from changing the calibration and retrieving the factory calibration.
- the user can make a calibration, for example, when a liquid is to be metered, which has a different density or viscosity than the factory calibration of the underlying fluid, or if you want to work at a different air pressure or temperature.
- This user calibration is done only by adjusting the bottom stop. The positioning of the upper stop made during factory calibration is therefore not changed.
- the display device displays the respective position of the holder holding the stop. The position taken by the lower stop during factory calibration can thus be found again at any time. This allows the user to find the factory calibration without expensive gravimetric measurement and without additional tools.
- the Piston stroke pipette thus again corresponds to the delivery state with regard to the calibration.
- the adjusting means for adjusting the position of the holder and thus the lower stop can be designed so that it is easy to operate without tools.
- the user calibration is therefore particularly easy to carry out. Included are both versions in which the upper stop is factory set once final, as well as versions that have an adjustable upper stop, which allows a later correction of factory calibration. A check and correction of the factory calibration may optionally be made in a conventional manner by adjusting the position of the upper stop.
- the pipette has a return spring, which loads the piston or the drive device in the direction of the abutment of the counter-stop on the upper stop.
- the piston is brought into a defined starting position, from which starting a dosing process can be started.
- This embodiment is particularly advantageous in manual Kolbenhubpipetten having a manually operable drive means.
- electronic pipettes having an electric drive means the initial positioning is done via an electronic control, so that a return spring can be omitted.
- the invention relates to both manual and electronic Kolbenhubpipetten.
- the drive device comprises a displaceable in a guide lifting rod, which is connected at one end to the piston or coupled and the other end is connected to a control knob.
- This embodiment particularly relates to manually operated piston stroke pipettes.
- the lifting rod is connected to the piston, for example, by being integrally formed with this or screwed to this or otherwise firmly connected to this.
- it can be coupled to the piston, for example, by abutting against an end face of the piston and held by the return spring in abutment becomes.
- This is particularly advantageous in the case of reciprocating pipettes with a top part comprising the drive device and a lower part which is detachable from it and comprises cylinders and pistons.
- the piston is movable, for example, by a motor-driven spindle.
- the counter-stop is a bead on the circumference of the lifting rod.
- the bead can rotate completely or partially around the circumference of the lifting rod.
- the lower stop plate-shaped and the lifting rod passed through a central through hole of the lower stop.
- the guided part of the lifting rod is connected to the piston or coupled.
- the lower stop is dome-shaped on the side facing the counter-stop.
- the centering of the lifting rod and the stop supporting embodiment the lower stop on the side facing away from the counter-stop on a sleeve-shaped projection, through which the through hole extends.
- the holder has the shape of a pot having in the bottom a central bottom hole through which the lifting rod is passed, the lower stop is slidably disposed in the holder, the holder has at its opening an inwardly projecting, the stop cross-over edge and is arranged in the holder, the over-travel spring and supported at one end on the ground and the other end on the underside of the stop.
- the lower stop is supported by an overstroke spring on the holder to blow out a liquid when dispensing liquid from a pipette tip to carry out residual liquid from the pipette tip.
- the user or the control electronics of an electronic pipette detects the achievement of the lower stop by the increased resistance at the beginning of the deformation of the over-travel spring.
- the drive device Before sucking liquid into the pipette tip, the drive device is only actuated until the counter-stop reaches the lower stop. When ejecting the liquid from the pipette tip of the counter-stop is pressed by means of the drive device against the lower stop, so that the over-stroke spring rebounds and residual liquid is blown out of the pipette tip.
- the overstroke spring and / or return spring is / are a helical spring.
- the adjusting means on an external thread on the holder and a cooperating, with respect to the cylinder fixed internal thread serve as adjusting thread for the positioning of the holder with respect to the cylinder.
- This embodiment is particularly in execution of the holder in the form of a pot of advantage.
- the holder is screwed manually after opening a housing of Kolbenhubpipette or with the aid of a tool.
- the adjusting devices have an actuator interacting with the holder.
- the actuator facilitates the adjustment of the lower stop, possibly without opening the pipette housing.
- the actuator has a calibration lever connected to the holder and / or a control gear coupled to the holder.
- a calibration lever or a setting gear is e.g. a holder in an internal thread screwed.
- the calibration lever is e.g. manually operable.
- the calibration lever is at the same time a pointer of the display device and, in the swivel range of the calibration lever, a scale of the display device fixed relative to the cylinder is assigned.
- the calibration lever is e.g. led out through a slot from a housing of Kolbenhubpipette so that it can be actuated from the outside.
- the calibration lever carries at its end a curved diaphragm which covers a slot in a housing fixed relative to the cylinder, to which a scale on the outer circumference of the housing is assigned.
- the shutter prevents dirt from entering through the slot in the housing.
- the actuating mechanism can be designed in different ways. Basically, all transmission types come into consideration, in particular gear transmission.
- the drive gear of the adjusting gear has a projecting from a housing actuating portion or is associated with a housing opening, through which it can be actuated from the outside.
- the holder on the casing has a scale of the display device, which is associated with a stationary relative to the cylinder marking of the display device.
- the scale is visible through a housing opening of a housing which has a mark on the housing opening or only lets the set scale value be visible from the outside.
- the actuating gear is a spur gear and / or a bevel gear.
- a piston stroke pipette with adjustable metering volume has a spindle which can be screwed into a spindle nut fixed with respect to the cylinder, the lower end face of which forms the upper stop, which has a through-channel through which the lifting rod is passed and in which the spindle is rotationally coupled to a volume adjusting device ,
- the volume adjusting device can be designed in various ways. In principle, it is possible to adjust the spindle directly and to provide this example by means of a manually operable actuator.
- the volume adjusting device comprises a coaxially receiving, rotatably mounted adjusting sleeve, which has inside axial grooves into which engages a driver which is rotatably connected to the spindle.
- the adjusting sleeve is coupled via a gear with a counter for displaying the volume setting.
- a device for decoupling two transmission elements of the transmission between adjusting sleeve and counter is present.
- the gearbox When the gearbox is decoupled, the upper stop can be moved by actuating the adjusting sleeve to carry out a factory calibration. After setting the upper stop, adjusting sleeve and counter are coupled together again.
- the gear has a gear set, which meshes with a gear on the circumference of the adjusting sleeve and a gear on an initial role of Zählrades and by means of the decoupling device with decoupling at least one gear along an axis is displaceable. This configuration results in a minimization of the meter jump result, ie the adjustment of the counter, the at Coupling due to the overlap of the gears of drive sleeve and counter comes about. This minimizes calibration errors.
- pistons, seat for the pipette tip, cylinder, connecting channel, drive device, stops, holders, overstroke spring, adjusting device and display device are arranged in or on a housing.
- the pipette is a hand-held pipette.
- the pipette is a manually operable pipette.
- a pipette 1 according to the invention has a housing 2 with an upper housing part 3 and a lower housing part 4.
- the lower housing part 4 comprises a cylinder 5 and a slightly conical, sleeve-shaped projection 6, which has a seat 7 for attaching a pipette tip at the end.
- the cylinder 5 is connected via a connecting channel 8 with an opening 9 in the center of the seat 7.
- the lower housing part 4 comprises a piston 10, which is guided into the cylinder 5 via a sealing system 11.
- the upper housing part 3 includes a lifting rod 12 whose lower end is connected via a coupling 13 with the piston 10. At the top, the lifting rod 12 carries an actuating button 14.
- the lifting rod 12 is passed through a spindle 15 arranged in the upper housing part 3.
- the spindle 15 has externally an external thread which can be screwed into an internal thread of a lifting body 16, which is fixed in the upper housing part 3.
- the lifting body 16 forms a spindle nut.
- the lower end face of the spindle 15 forms an upper stop 17 for an annular bead 18 on the circumference of the lifting rod 12.
- the spindle 15 is rotatably connected to a driver 19 at the upper end.
- the driver 19 engages by means of radially projecting ribs 20 in axial grooves of an adjusting sleeve 21 a.
- the adjusting sleeve 21 is arranged concentrically to the spindle 15 and rotatably supported between the lifting body 16 and the upper housing part 3.
- the adjusting sleeve 21 protrudes with an upper actuating end, which has a corrugation 22 at the top of the circumference, out of the upper housing part 3.
- the adjusting sleeve 21 has at the bottom of the circumference a gear 23. Further, a counter 24 is provided with a further gear 25 at an initial role. The number wheels of the counter 25 are visible from outside the housing upper part 3 through a window 26 having a transparent cover 27.
- a gear set 29 is mounted on an axle 28.
- the gear set 29 is connected to a sliding on the axis 28 adjusting block 30.
- a guided on the axis 28 coil spring 31 so that the gear set 29 presses the adjusting block 30 against a seated on the axis 28 ring 32.
- a Abwerferknopf 36 on a Abwerferstange 37 runs parallel to the lifting rod 12 through the upper housing part 3. Its lower end is connected to a lateral attachment lug 38 of a Abwerferhülse 39 which is slidably mounted on the conical projection 6.
- the upper housing part 3 has a window 40, through which the notch 33 of the adjusting block 30 is accessible from the outside.
- a cup-shaped holder 41 is disposed below the lifting body 16.
- the holder 41 has an external thread, which is screwably arranged in an internal thread of a housing-fixed carrier 42.
- the holder 41 includes a plate-shaped lower stop 43, which is held under an inwardly bent, upper edge 44 of the holder 41.
- An overstroke spring 45 which is supported on the bottom of the holder 41, presses the lower stop 43 against the edge 44th
- the lifting rod 12 is passed through central passages of the lower stop 43, by the overstroke spring 45 and a central passage in the bottom of the holder 41.
- a radially projecting calibration lever 46 is connected, which protrudes through a slot 47 from the upper housing part 3.
- the calibration lever 46 is laterally connected to a diaphragm 48, which prevents dust from entering the slot 47 from the outside.
- the upper housing part 3 has on one side of the slot a scale 49, which is assigned to the calibration lever 46 in the manner of a pointer.
- the piston 10 is displaced by depressing the actuating knob 14 against the action of a return spring in the cylinder 5, wherein the piston stroke defined by the distance of the upper stop 17 from the lower stop 43 is, between which the counter-stop 18 is displaced. If the counter-stop 18 reaches the lower stop 43, an overstroke is also possible until the over-travel spring 45 moves "on block".
- the calibration lever 46 is set to the latched zero point of the scale 49.
- the factory calibration is done by decoupling the counter 24 of the adjusting sleeve 21. In this case, the counter 24 is adjusted until the display corresponds to the set dosing.
- This first calibration option is used for permanent calibration ex works and in case of service.
- the second calibration option is used to temporarily recalibrate the pipette for different media and ambient conditions (density, vapor pressure, temperature, etc.).
- the over-lift system is adjusted by operating the calibration lever 46. If the holder 41 is raised, this means a volume reduction. If it is lowered, the dosing volume is increased. If the user wishes to return from the user calibration he has made to the factory calibration, he only needs to turn the calibration lever 46 back into its latched starting position.
Claims (27)
- Pipette à piston pour pointes de pipette remplaçables, avec• un siège (7) pour la fixation amovible d'une pointe de pipette,• un piston (10)• un cylindre (5), dans lequel le piston (10) est disposé de façon déplaçable,• un canal de jonction (8) reliant le cylindre (5) avec une ouverture (9) dans le siège (7),• un dispositif d'entraînement (12) couplé avec le piston (10) pour déplacer le piston (10) dans le cylindre (5),• une butée supérieure (17) et une butée inférieure (43) et au moins une contre-butée (18) du dispositif d'entraînement (12) et/ou du piston (10) pour limiter la course du piston (10),• un crochet (41) qui tient la butée inférieure (43),• un ressort de surcourse (45) entre la butée inférieure (43) et le crochet (41),caractérisé en ce que la pipette à piston présente• un dispositif d'ajustage (46) pour ajuster la position du crochet (41) par rapport au cylindre (10) et• un dispositif d'indication (49) pour indiquer la position du crochet.
- Pipette selon la revendication 1, qui présente un ressort de rappel qui charge le piston (10) ou le dispositif d'entraînement (12) dans la direction de l'appui de la contre-butée (18) sur la butée supérieure (17).
- Pipette selon la revendication 1 ou 2, dans laquelle le dispositif d'entraînement possède une tige du piston (12) déplaçable dans une coulisse, qui est solidaire ou adaptée à être couplé avec le piston (10) dans une extrémité, et qui est reliée avec un bouton de commande (14) dans l'autre extrémité.
- Pipette selon la revendication 3, dans laquelle la contre-butée (18) est un bourrelet sur la circonférence de la tige du piston (12).
- Pipette selon la revendication 3 ou 4, dans laquelle la butée inférieure (43) est en forme d'assiette, et la tige du piston (12) est guidée à travers un trou de passage central de la butée inférieure (43).
- Pipette selon la revendication 5, dans laquelle la butée inférieure (43) est en forme de calotte sur le coté tourné vers la contre-butée (18).
- Pipette selon la revendication 5 ou 6, dans laquelle la butée inférieure (43) a une saillie en forme de manchon sur son coté détourné de la contre-butée (18), à travers laquelle s'écoule le trou de passage.
- Pipette selon l'une quelconque des revendications 5 à 7, dans laquelle le crochet (41) présente la forme d'un pot qui a un trou de fond central dans son fond à travers duquel la tige du piston (12) est guidée, la butée inférieure (43) est disposée de façon déplaçable dans le crochet (41), le crochet (41) présente sur son ouverture un bord (44) qui dépasse vers l'intérieur et recouvre la butée, et le ressort de surcourse (45) est disposé dans le crochet (41) et est contrebuté sur le fond dans l'une extrémité et dans le côté inférieur de la butée (43) dans l'autre extrémité.
- Pipette selon l'une quelconque des revendications 1 à 8, dans laquelle le ressort de surcourse (45) et/ou le ressort de rappel est/sont un ressort cylindrique.
- Pipette selon l'une quelconque des revendications 1 à 9, dans laquelle les dispositifs d'ajustage présentent un filet extérieur sur le crochet (41) et un filet intérieur concourant avec ceci et qui est stationnaire par rapport au cylindre (5).
- Pipette selon l'une quelconque des revendications 1 à 10, dans laquelle les dispositifs d'ajustage présentent un servomoteur (38; 50, 51) concourant avec le crochet (41).
- Pipette selon la revendication 11, dans laquelle le servomoteur présente un levier de calibrage (46) lié avec le crochet, et/ou un mécanisme de réglage couplé avec le crochet.
- Pipette selon la revendication 12, dans laquelle une échelle (49) du dispositif d'indication, stationnaire par rapport au cylindre (5), est associé à la gamme de basculement du levier de calibrage (46) comme l'index du dispositif d'indication.
- Pipette selon la revendication 12 ou 13, dans laquelle le levier de calibrage (46) porte dans son extrémité un écran (48) en forme d'anneau de cercle, qui couvre une rainure (47) dans un boîtier (2) stationnaire par rapport au cylindre (5) à laquelle est associée une échelle (49) dans la circonférence extérieure du boîtier (2).
- Pipette selon l'une quelconque des revendications 1 à 14, dans laquelle le mécanisme de réglage présente une roue dentée entraînée (50) sur la circonférence du crochet (41') et une roue dentée motrice (51) actionnable par main et engrenant avec celle-ci.
- Pipette selon la revendication 15, dans laquelle la roue dentée motrice (51) du mécanisme de réglage présente une partie d'actionnement faisant saillie du boîtier (2) ou est associée à une ouverture du boîtier à travers laquelle elle est actionnable du dehors.
- Pipette selon l'une quelconque des revendications 10 à 16, dans laquelle le crochet (41') présente une échelle (53) du dispositif d'indication dans sa circonférence, à laquelle est associée une marque (55) du dispositif d'indication qui est stationnaire par rapport au cylindre (5).
- Pipette selon la revendication 17, dans laquelle l'échelle est visible à travers une ouverture (54) de boîtier d'un boîtier (2).
- Pipette selon l'une quelconque des revendications 1 à 18, dans laquelle le mécanisme de réglage est un engrenage hélicoidal (50, 51) et/ou un engrenage conique.
- Pipette selon l'une quelconque des revendications 1 à 19, qui présente une broche (15) vissable dans un écrou de broche stationnaire par rapport au cylindre (5), le côté de front inférieur de la broche formant la butée supérieure (17) et présentant un canal de passage à travers lequel la tige du piston (12) est guidée, la broche étant couplée de manière tournante avec un dispositif d'ajustage de volume (21).
- Pipette selon la revendication 20, dans laquelle le dispositif d'ajustage de volume présente un manchon d'ajustage (21) logeant coaxialement la broche (15) et qui présente des gorges axiales dans son intérieur dans lesquelles s'engage un entraîneur (19) qui est lié fixe en rotation avec la broche (15).
- Pipette selon la revendication 21, dans laquelle le manchon d'ajustage (21) est couplé par un engrenage (23, 25, 29) avec un numérateur (24) pour indiquer l'ajustage de volume.
- Pipette selon la revendication 22, dans laquelle existe un dispositif pour découpler (30) deux éléments d'engrenage de l'engrenage (23, 25, 29) entre le manchon d'ajustage (21) et le numérateur (24).
- Pipette selon la revendication 23, dans laquelle l'engrenage (23, 25, 29) présente un jeu de roues dentées (29) qui s'engrène avec une roue dentée sur la circonférence du manchon d'ajustage (21) et avec une roue dentée sur le premier rouleau du numérateur (24) et qui peut être déplacé le long d'un axe (28) par le biais du dispositif pour découpler (30) en découplant au moins une roue dentée (23, 25) d'une roue dentée dont elle s'engrène.
- Pipette selon l'une quelconque des revendications 1 à 24, qui présente le piston (10), le siège (7), le cylindre (5), le canal de jonction (8), le dispositif d'entraînement (12), les butées (17, 43), le crochet (41), le ressort de surcourse (45), le dispositif d'ajustage (46) et le dispositif d'indication (49) dans ou sur un boîtier (2).
- Pipette selon l'une quelconque des revendications 1 à 25, qui est une pipette tenue par la main.
- Pipette selon l'une quelconque des revendications 1 à 26, qui est une pipette actionnable par la main.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102005033378A DE102005033378B4 (de) | 2005-07-16 | 2005-07-16 | Kolbenhubpipette |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1743701A1 EP1743701A1 (fr) | 2007-01-17 |
EP1743701B1 true EP1743701B1 (fr) | 2009-09-23 |
Family
ID=36975527
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP06010457A Active EP1743701B1 (fr) | 2005-07-16 | 2006-05-20 | Pipette à piston |
Country Status (3)
Country | Link |
---|---|
US (1) | US8133453B2 (fr) |
EP (1) | EP1743701B1 (fr) |
DE (2) | DE102005033378B4 (fr) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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DE102012003846A1 (de) | 2012-02-29 | 2013-08-29 | Eppendorf Ag | Pipette |
EP3915682A1 (fr) | 2020-05-25 | 2021-12-01 | Eppendorf AG | Pipette à volume de dosage réglable |
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Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2291245A1 (fr) * | 2008-04-08 | 2011-03-09 | Socorex Isba S.A. | Joint pour dispositif de dosage de liquides |
DE102008048252A1 (de) | 2008-09-12 | 2010-04-15 | Eppendorf Ag | Pipettiervorrichtung |
JP2011115759A (ja) * | 2009-12-07 | 2011-06-16 | Fukae Kasei Kk | ピペット装置 |
US9044749B2 (en) | 2012-02-29 | 2015-06-02 | Eppendorf Ag | Pipette |
US9579644B2 (en) * | 2012-04-23 | 2017-02-28 | Eppendorf Ag | Pipette for operating a syringe |
US10016755B2 (en) | 2015-01-08 | 2018-07-10 | Integra Biosciences Ag | Manual pipette with selectable plunger force |
EP3283220B1 (fr) * | 2015-04-16 | 2019-07-03 | Integra Biosciences AG | Dispositif d'ajustement du volume pour pipeteur manuel |
EP3302800B1 (fr) | 2015-06-05 | 2019-08-14 | Mimetas B.V. | Plaque microfluidique |
CN105618169B (zh) * | 2015-12-21 | 2017-06-16 | 安徽农业大学 | 一种等量连续点滴移液枪 |
DE102016121814A1 (de) | 2016-11-14 | 2018-05-17 | Ika-Werke Gmbh & Co. Kg | Handdosiervorrichtung |
US10744498B2 (en) * | 2017-09-19 | 2020-08-18 | Mettler-Toledo Rainin, LLC | Pipette quickset volume adjustment mechanism |
EP3778028B1 (fr) * | 2019-08-15 | 2021-10-06 | Eppendorf AG | Pipette à volume de dosage réglable |
EP3978130A1 (fr) * | 2020-09-30 | 2022-04-06 | iCare Diagnostics International Co. Ltd. | Dispositif de transfert de liquide |
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DE102021117128B4 (de) | 2021-07-02 | 2023-03-30 | Brand Gmbh + Co Kg | Pipettiervorrichtung |
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-
2005
- 2005-07-16 DE DE102005033378A patent/DE102005033378B4/de not_active Expired - Fee Related
-
2006
- 2006-05-20 EP EP06010457A patent/EP1743701B1/fr active Active
- 2006-05-20 DE DE502006004903T patent/DE502006004903D1/de active Active
- 2006-05-31 US US11/443,728 patent/US8133453B2/en active Active
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102012003846A1 (de) | 2012-02-29 | 2013-08-29 | Eppendorf Ag | Pipette |
EP2633915A2 (fr) | 2012-02-29 | 2013-09-04 | Eppendorf Ag | Pipette |
EP3915682A1 (fr) | 2020-05-25 | 2021-12-01 | Eppendorf AG | Pipette à volume de dosage réglable |
Also Published As
Publication number | Publication date |
---|---|
EP1743701A1 (fr) | 2007-01-17 |
DE102005033378B4 (de) | 2012-05-31 |
US8133453B2 (en) | 2012-03-13 |
DE102005033378A1 (de) | 2007-01-18 |
US20070014696A1 (en) | 2007-01-18 |
DE502006004903D1 (de) | 2009-11-05 |
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