EP1692106A1 - Neue synthese von 2-azabicyclischen 3-carbonsäuren, die sich als wichtige arzneimittelzwischenprodukte eignen - Google Patents

Neue synthese von 2-azabicyclischen 3-carbonsäuren, die sich als wichtige arzneimittelzwischenprodukte eignen

Info

Publication number
EP1692106A1
EP1692106A1 EP03782763A EP03782763A EP1692106A1 EP 1692106 A1 EP1692106 A1 EP 1692106A1 EP 03782763 A EP03782763 A EP 03782763A EP 03782763 A EP03782763 A EP 03782763A EP 1692106 A1 EP1692106 A1 EP 1692106A1
Authority
EP
European Patent Office
Prior art keywords
formula
compound
give
acid
toluene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03782763A
Other languages
English (en)
French (fr)
Inventor
Potluri Ramesh Babu
Venkata Subramanian Hariharakrishnan
Tadimalla Venkata Srihari
Kodali Hari Prasad
Betini Ramesh
Gottimukkala Venkata Mallaparaju
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP1692106A1 publication Critical patent/EP1692106A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EP03782763A 2003-11-24 2003-11-24 Neue synthese von 2-azabicyclischen 3-carbonsäuren, die sich als wichtige arzneimittelzwischenprodukte eignen Withdrawn EP1692106A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IN2003/000367 WO2005049567A1 (en) 2003-11-24 2003-11-24 A novel synthesis of 2-azabicyclic-3-carboxylic acids, useful as important drug intermediates

Publications (1)

Publication Number Publication Date
EP1692106A1 true EP1692106A1 (de) 2006-08-23

Family

ID=34611186

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03782763A Withdrawn EP1692106A1 (de) 2003-11-24 2003-11-24 Neue synthese von 2-azabicyclischen 3-carbonsäuren, die sich als wichtige arzneimittelzwischenprodukte eignen

Country Status (3)

Country Link
EP (1) EP1692106A1 (de)
AU (1) AU2003290400A1 (de)
WO (1) WO2005049567A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100376556C (zh) * 2005-10-14 2008-03-26 浙江工业大学 2-氮杂双环[3,3,0]辛烷-3-羧酸盐酸盐的制备方法
DE102005061756B4 (de) * 2005-12-21 2008-01-03 Sanofi-Aventis Deutschland Gmbh Verbessertes Verfahren zur Herstellung von Ramipril
US20100143981A1 (en) * 2006-12-04 2010-06-10 Rusnak-Mueller Monika Whole-cell catalytic system comprising a hydantoinase, a racemase and a carbamoylase
ATE536342T1 (de) * 2007-10-17 2011-12-15 Dsm Ip Assets Bv Neue carbamoylglycinderivate
US8263784B2 (en) 2008-10-30 2012-09-11 Dsm Sinochem Pharmaceuticals Netherlands B.V. Method for the synthesis of a ramipril intermediate
HUE039419T2 (hu) * 2014-06-11 2018-12-28 Sanofi Aventis Deutschland Eljárás ramipril elõállítására
CN104817486B (zh) * 2015-03-31 2018-05-22 浙江工业大学 一种雷米普利中间体的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3431541A1 (de) * 1984-08-28 1986-03-06 Hoechst Ag, 6230 Frankfurt Cis,endo-2-azabicycloalkan-3-carbonsaeure-derivate, verfahren zu deren herstellung, deren verwendung sowie zwischenprodukte bei deren herstellung

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2005049567A1 *

Also Published As

Publication number Publication date
WO2005049567A1 (en) 2005-06-02
AU2003290400A1 (en) 2005-06-08

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