EP1430150A2 - Diagnostisches sondennachweissystem - Google Patents
Diagnostisches sondennachweissystemInfo
- Publication number
- EP1430150A2 EP1430150A2 EP02761809A EP02761809A EP1430150A2 EP 1430150 A2 EP1430150 A2 EP 1430150A2 EP 02761809 A EP02761809 A EP 02761809A EP 02761809 A EP02761809 A EP 02761809A EP 1430150 A2 EP1430150 A2 EP 1430150A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- target
- probe
- region
- nucleic acid
- complementary
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP15002428.9A EP2980222A1 (de) | 2001-09-24 | 2002-09-24 | Diagnosesondendetektionssystem |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32442101P | 2001-09-24 | 2001-09-24 | |
US324421P | 2001-09-24 | ||
PCT/US2002/030238 WO2003027309A2 (en) | 2001-09-24 | 2002-09-24 | Diagnostic probe detection system |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP15002428.9A Division EP2980222A1 (de) | 2001-09-24 | 2002-09-24 | Diagnosesondendetektionssystem |
Publications (3)
Publication Number | Publication Date |
---|---|
EP1430150A2 true EP1430150A2 (de) | 2004-06-23 |
EP1430150A4 EP1430150A4 (de) | 2005-02-02 |
EP1430150B1 EP1430150B1 (de) | 2015-08-19 |
Family
ID=23263504
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP15002428.9A Withdrawn EP2980222A1 (de) | 2001-09-24 | 2002-09-24 | Diagnosesondendetektionssystem |
EP02761809.9A Expired - Lifetime EP1430150B1 (de) | 2001-09-24 | 2002-09-24 | Diagnostisches sondennachweissystem |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP15002428.9A Withdrawn EP2980222A1 (de) | 2001-09-24 | 2002-09-24 | Diagnosesondendetektionssystem |
Country Status (8)
Country | Link |
---|---|
US (2) | US8512953B2 (de) |
EP (2) | EP2980222A1 (de) |
JP (1) | JP2005504281A (de) |
CN (2) | CN1312289C (de) |
AU (1) | AU2002327046B2 (de) |
BR (1) | BR0212773A (de) |
CA (1) | CA2460759C (de) |
WO (1) | WO2003027309A2 (de) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003027309A2 (en) * | 2001-09-24 | 2003-04-03 | One Lambda | Diagnostic probe detection system |
CN1330775C (zh) * | 2002-05-08 | 2007-08-08 | 爱科来株式会社 | 靶核酸的检测方法 |
GB2395556A (en) * | 2002-11-22 | 2004-05-26 | Dynal Biotech Ltd | Nucleic acid probe |
GB2395557A (en) * | 2002-11-22 | 2004-05-26 | Dynal Biotech Ltd | Nucleic acid probes |
AU2004235747B2 (en) * | 2003-05-01 | 2009-05-28 | Gen-Probe Incorporated | Oligonucleotides comprising a molecular switch |
EP1713911A4 (de) | 2003-12-25 | 2008-02-20 | Kenmoku Takashi | Sondensatz und verfahren zur identifizierung des hla-allels |
JP2006166911A (ja) * | 2004-11-19 | 2006-06-29 | Wakunaga Pharmaceut Co Ltd | 核酸検出用核酸断片および核酸検出方法 |
EP1816195A4 (de) * | 2004-11-19 | 2009-06-03 | Wakunaga Pharma Co Ltd | Nukleinsäurefragmente zum nachweis von nukleinsäure und verfahren zum nachweis von nukleinsäure |
WO2006076650A2 (en) * | 2005-01-12 | 2006-07-20 | Applera Corporation | Compositions, methods, and kits for selective amplification of nucleic acids |
JP2009501531A (ja) * | 2005-07-15 | 2009-01-22 | アプレラ コーポレイション | Rnaプロファイリングのための方法 |
GB0703996D0 (en) * | 2007-03-01 | 2007-04-11 | Oxitec Ltd | Nucleic acid detection |
GB0703997D0 (en) | 2007-03-01 | 2007-04-11 | Oxitec Ltd | Methods for detecting nucleic sequences |
JP5143450B2 (ja) * | 2007-03-14 | 2013-02-13 | 斉 大戸 | Hla−bローカスにおける新規アリル |
CA2686211C (en) | 2007-05-03 | 2018-08-21 | One Lambda Inc. | Methods of screening for binding interaction using sets of microparticles and unique probes |
WO2011006119A2 (en) | 2009-07-09 | 2011-01-13 | The Scripps Research Institute | Gene expression profiles associated with chronic allograft nephropathy |
US8409802B2 (en) * | 2009-08-14 | 2013-04-02 | Roche Molecular Systems, Inc. | Format of probes to detect nucleic acid differences |
EP3696277B1 (de) | 2013-07-30 | 2023-01-25 | President and Fellows of Harvard College | Quantitative dna-basierte bildgebung und hochauflösende bildgebung |
US10443100B2 (en) | 2014-05-22 | 2019-10-15 | The Scripps Research Institute | Gene expression profiles associated with sub-clinical kidney transplant rejection |
US11104951B2 (en) | 2014-05-22 | 2021-08-31 | The Scripps Research Institute | Molecular signatures for distinguishing liver transplant rejections or injuries |
JP6495333B2 (ja) | 2014-12-19 | 2019-04-03 | 栄研化学株式会社 | 一塩基多型検出用オリゴヌクレオチドプローブ及び一塩基多型検出方法 |
CN107828889B (zh) * | 2017-11-13 | 2021-06-11 | 首都医科大学附属北京儿童医院 | 一种用于hla-drb1*03基因定性检测的pcr扩增引物及试剂盒 |
US10323272B1 (en) | 2018-01-31 | 2019-06-18 | Enzo Biochem, Inc. | Nucleic acid probes for in situ hybridization |
CN111615561A (zh) * | 2018-03-15 | 2020-09-01 | 荣研化学株式会社 | 单核苷酸多态性检测用寡核苷酸探针和顺式-反式判别方法 |
EP4367673A1 (de) * | 2021-07-06 | 2024-05-15 | Switch Therapeutics Inc. | Verfahren zur erzeugung von kernsträngen in konditionell aktivierbaren nukleinsäurekomplexen |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0450594A2 (de) * | 1990-04-03 | 1991-10-09 | David Segev | Signalamplifikation einer DNS-Sonde |
WO2000079006A1 (en) * | 1999-06-17 | 2000-12-28 | Fred Hutchinson Cancer Research Center | Oligonucleotide arrays for high resolution hla typing |
US20010019825A1 (en) * | 1998-09-11 | 2001-09-06 | One Lambda | Method for amplification of DNA |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4957858A (en) | 1986-04-16 | 1990-09-18 | The Salk Instute For Biological Studies | Replicative RNA reporter systems |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US4835098A (en) * | 1985-09-04 | 1989-05-30 | Regents Of University Of Minnesota | Characterization of HLA alleles with locus-specific DNA probes |
US4946773A (en) * | 1985-12-23 | 1990-08-07 | President And Fellows Of Harvard College | Detection of base pair mismatches using RNAase A |
CA1284931C (en) | 1986-03-13 | 1991-06-18 | Henry A. Erlich | Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids |
CA1338457C (en) | 1986-08-22 | 1996-07-16 | Henry A. Erlich | Purified thermostable enzyme |
IL86724A (en) | 1987-06-19 | 1995-01-24 | Siska Diagnostics Inc | Methods and kits for amplification and testing of nucleic acid sequences |
US6031091A (en) * | 1987-09-21 | 2000-02-29 | Gen-Probe Incorporated | Non-nucleotide linking reagents for nucleotide probes |
IE61148B1 (en) | 1988-03-10 | 1994-10-05 | Ici Plc | Method of detecting nucleotide sequences |
JP2781438B2 (ja) | 1988-10-20 | 1998-07-30 | モーリィ,アリグザンダー,アラン | 白血病及びリンパ腫におけるモノクローナリテイーの診断法 |
US5424413A (en) * | 1992-01-22 | 1995-06-13 | Gen-Probe Incorporated | Branched nucleic acid probes |
JP3595841B2 (ja) | 1992-12-04 | 2004-12-02 | サーナ セラピューティクス,インコーポレイテッド | リボザイム増幅診断用薬 |
US6207373B1 (en) * | 1998-02-25 | 2001-03-27 | Nanogen, Inc. | Methods for determining nature of repeat units in DNA |
US5518884A (en) * | 1994-02-28 | 1996-05-21 | Becton, Dickinson And Company | Nucleic acid sequences specific for mycbacterium kansasii |
US5753439A (en) * | 1995-05-19 | 1998-05-19 | Trustees Of Boston University | Nucleic acid detection methods |
US5854033A (en) * | 1995-11-21 | 1998-12-29 | Yale University | Rolling circle replication reporter systems |
US5589322A (en) * | 1995-12-12 | 1996-12-31 | Eastman Kodak Company | Process for making a direct dispersion of a photographically useful material |
CA2239683A1 (en) * | 1995-12-22 | 1997-07-03 | Dade Behring Marburg Gmbh | Homogeneous amplification and detection of nucleic acids |
US5785835A (en) | 1996-04-12 | 1998-07-28 | One Lambda | Electrophoresis method and devices |
US5780233A (en) * | 1996-06-06 | 1998-07-14 | Wisconsin Alumni Research Foundation | Artificial mismatch hybridization |
US6194149B1 (en) * | 1998-03-03 | 2001-02-27 | Third Wave Technologies, Inc. | Target-dependent reactions using structure-bridging oligonucleotides |
US6806051B2 (en) * | 2000-09-25 | 2004-10-19 | Picoliter Inc. | Arrays of partially nonhybridizing oligonucleotides and preparation thereof using focused acoustic energy |
US6350580B1 (en) * | 2000-10-11 | 2002-02-26 | Stratagene | Methods for detection of a target nucleic acid using a probe comprising secondary structure |
US6573051B2 (en) * | 2001-03-09 | 2003-06-03 | Molecular Staging, Inc. | Open circle probes with intramolecular stem structures |
WO2003052116A2 (en) * | 2001-07-17 | 2003-06-26 | Stratagene | Methods for detection of a target nucleic acid using multi-subunit probes |
WO2003027309A2 (en) * | 2001-09-24 | 2003-04-03 | One Lambda | Diagnostic probe detection system |
-
2002
- 2002-09-24 WO PCT/US2002/030238 patent/WO2003027309A2/en active Application Filing
- 2002-09-24 BR BR0212773-3A patent/BR0212773A/pt not_active Application Discontinuation
- 2002-09-24 US US10/253,967 patent/US8512953B2/en active Active
- 2002-09-24 CN CNB028232720A patent/CN1312289C/zh not_active Ceased
- 2002-09-24 EP EP15002428.9A patent/EP2980222A1/de not_active Withdrawn
- 2002-09-24 CA CA2460759A patent/CA2460759C/en not_active Expired - Lifetime
- 2002-09-24 AU AU2002327046A patent/AU2002327046B2/en not_active Expired
- 2002-09-24 CN CNA2007100877390A patent/CN101074450A/zh active Pending
- 2002-09-24 JP JP2003530874A patent/JP2005504281A/ja active Pending
- 2002-09-24 EP EP02761809.9A patent/EP1430150B1/de not_active Expired - Lifetime
-
2013
- 2013-08-14 US US13/967,249 patent/US9988671B2/en not_active Expired - Lifetime
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0450594A2 (de) * | 1990-04-03 | 1991-10-09 | David Segev | Signalamplifikation einer DNS-Sonde |
US20010019825A1 (en) * | 1998-09-11 | 2001-09-06 | One Lambda | Method for amplification of DNA |
WO2000079006A1 (en) * | 1999-06-17 | 2000-12-28 | Fred Hutchinson Cancer Research Center | Oligonucleotide arrays for high resolution hla typing |
Non-Patent Citations (1)
Title |
---|
See also references of WO03027309A2 * |
Also Published As
Publication number | Publication date |
---|---|
US20030165925A1 (en) | 2003-09-04 |
US20130330725A1 (en) | 2013-12-12 |
JP2005504281A (ja) | 2005-02-10 |
CA2460759C (en) | 2011-05-31 |
WO2003027309A3 (en) | 2003-10-16 |
CN1312289C (zh) | 2007-04-25 |
EP1430150B1 (de) | 2015-08-19 |
EP1430150A4 (de) | 2005-02-02 |
EP2980222A1 (de) | 2016-02-03 |
US8512953B2 (en) | 2013-08-20 |
AU2002327046B2 (en) | 2007-11-29 |
US9988671B2 (en) | 2018-06-05 |
CN1589331A (zh) | 2005-03-02 |
CA2460759A1 (en) | 2003-04-03 |
BR0212773A (pt) | 2004-10-13 |
CN101074450A (zh) | 2007-11-21 |
WO2003027309A2 (en) | 2003-04-03 |
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