EP1430150A2 - Diagnostisches sondennachweissystem - Google Patents

Diagnostisches sondennachweissystem

Info

Publication number
EP1430150A2
EP1430150A2 EP02761809A EP02761809A EP1430150A2 EP 1430150 A2 EP1430150 A2 EP 1430150A2 EP 02761809 A EP02761809 A EP 02761809A EP 02761809 A EP02761809 A EP 02761809A EP 1430150 A2 EP1430150 A2 EP 1430150A2
Authority
EP
European Patent Office
Prior art keywords
target
probe
region
nucleic acid
complementary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP02761809A
Other languages
English (en)
French (fr)
Other versions
EP1430150B1 (de
EP1430150A4 (de
Inventor
Katsuyuki Saito
Jar-How Lee
Lindley Blair
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
One Lambda Inc
Original Assignee
One Lambda Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23263504&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP1430150(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by One Lambda Inc filed Critical One Lambda Inc
Priority to EP15002428.9A priority Critical patent/EP2980222A1/de
Publication of EP1430150A2 publication Critical patent/EP1430150A2/de
Publication of EP1430150A4 publication Critical patent/EP1430150A4/de
Application granted granted Critical
Publication of EP1430150B1 publication Critical patent/EP1430150B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
EP02761809.9A 2001-09-24 2002-09-24 Diagnostisches sondennachweissystem Expired - Lifetime EP1430150B1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP15002428.9A EP2980222A1 (de) 2001-09-24 2002-09-24 Diagnosesondendetektionssystem

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US32442101P 2001-09-24 2001-09-24
US324421P 2001-09-24
PCT/US2002/030238 WO2003027309A2 (en) 2001-09-24 2002-09-24 Diagnostic probe detection system

Related Child Applications (1)

Application Number Title Priority Date Filing Date
EP15002428.9A Division EP2980222A1 (de) 2001-09-24 2002-09-24 Diagnosesondendetektionssystem

Publications (3)

Publication Number Publication Date
EP1430150A2 true EP1430150A2 (de) 2004-06-23
EP1430150A4 EP1430150A4 (de) 2005-02-02
EP1430150B1 EP1430150B1 (de) 2015-08-19

Family

ID=23263504

Family Applications (2)

Application Number Title Priority Date Filing Date
EP15002428.9A Withdrawn EP2980222A1 (de) 2001-09-24 2002-09-24 Diagnosesondendetektionssystem
EP02761809.9A Expired - Lifetime EP1430150B1 (de) 2001-09-24 2002-09-24 Diagnostisches sondennachweissystem

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP15002428.9A Withdrawn EP2980222A1 (de) 2001-09-24 2002-09-24 Diagnosesondendetektionssystem

Country Status (8)

Country Link
US (2) US8512953B2 (de)
EP (2) EP2980222A1 (de)
JP (1) JP2005504281A (de)
CN (2) CN1312289C (de)
AU (1) AU2002327046B2 (de)
BR (1) BR0212773A (de)
CA (1) CA2460759C (de)
WO (1) WO2003027309A2 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003027309A2 (en) * 2001-09-24 2003-04-03 One Lambda Diagnostic probe detection system
CN1330775C (zh) * 2002-05-08 2007-08-08 爱科来株式会社 靶核酸的检测方法
GB2395556A (en) * 2002-11-22 2004-05-26 Dynal Biotech Ltd Nucleic acid probe
GB2395557A (en) * 2002-11-22 2004-05-26 Dynal Biotech Ltd Nucleic acid probes
AU2004235747B2 (en) * 2003-05-01 2009-05-28 Gen-Probe Incorporated Oligonucleotides comprising a molecular switch
EP1713911A4 (de) 2003-12-25 2008-02-20 Kenmoku Takashi Sondensatz und verfahren zur identifizierung des hla-allels
JP2006166911A (ja) * 2004-11-19 2006-06-29 Wakunaga Pharmaceut Co Ltd 核酸検出用核酸断片および核酸検出方法
EP1816195A4 (de) * 2004-11-19 2009-06-03 Wakunaga Pharma Co Ltd Nukleinsäurefragmente zum nachweis von nukleinsäure und verfahren zum nachweis von nukleinsäure
WO2006076650A2 (en) * 2005-01-12 2006-07-20 Applera Corporation Compositions, methods, and kits for selective amplification of nucleic acids
JP2009501531A (ja) * 2005-07-15 2009-01-22 アプレラ コーポレイション Rnaプロファイリングのための方法
GB0703996D0 (en) * 2007-03-01 2007-04-11 Oxitec Ltd Nucleic acid detection
GB0703997D0 (en) 2007-03-01 2007-04-11 Oxitec Ltd Methods for detecting nucleic sequences
JP5143450B2 (ja) * 2007-03-14 2013-02-13 斉 大戸 Hla−bローカスにおける新規アリル
CA2686211C (en) 2007-05-03 2018-08-21 One Lambda Inc. Methods of screening for binding interaction using sets of microparticles and unique probes
WO2011006119A2 (en) 2009-07-09 2011-01-13 The Scripps Research Institute Gene expression profiles associated with chronic allograft nephropathy
US8409802B2 (en) * 2009-08-14 2013-04-02 Roche Molecular Systems, Inc. Format of probes to detect nucleic acid differences
EP3696277B1 (de) 2013-07-30 2023-01-25 President and Fellows of Harvard College Quantitative dna-basierte bildgebung und hochauflösende bildgebung
US10443100B2 (en) 2014-05-22 2019-10-15 The Scripps Research Institute Gene expression profiles associated with sub-clinical kidney transplant rejection
US11104951B2 (en) 2014-05-22 2021-08-31 The Scripps Research Institute Molecular signatures for distinguishing liver transplant rejections or injuries
JP6495333B2 (ja) 2014-12-19 2019-04-03 栄研化学株式会社 一塩基多型検出用オリゴヌクレオチドプローブ及び一塩基多型検出方法
CN107828889B (zh) * 2017-11-13 2021-06-11 首都医科大学附属北京儿童医院 一种用于hla-drb1*03基因定性检测的pcr扩增引物及试剂盒
US10323272B1 (en) 2018-01-31 2019-06-18 Enzo Biochem, Inc. Nucleic acid probes for in situ hybridization
CN111615561A (zh) * 2018-03-15 2020-09-01 荣研化学株式会社 单核苷酸多态性检测用寡核苷酸探针和顺式-反式判别方法
EP4367673A1 (de) * 2021-07-06 2024-05-15 Switch Therapeutics Inc. Verfahren zur erzeugung von kernsträngen in konditionell aktivierbaren nukleinsäurekomplexen

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0450594A2 (de) * 1990-04-03 1991-10-09 David Segev Signalamplifikation einer DNS-Sonde
WO2000079006A1 (en) * 1999-06-17 2000-12-28 Fred Hutchinson Cancer Research Center Oligonucleotide arrays for high resolution hla typing
US20010019825A1 (en) * 1998-09-11 2001-09-06 One Lambda Method for amplification of DNA

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4957858A (en) 1986-04-16 1990-09-18 The Salk Instute For Biological Studies Replicative RNA reporter systems
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4835098A (en) * 1985-09-04 1989-05-30 Regents Of University Of Minnesota Characterization of HLA alleles with locus-specific DNA probes
US4946773A (en) * 1985-12-23 1990-08-07 President And Fellows Of Harvard College Detection of base pair mismatches using RNAase A
CA1284931C (en) 1986-03-13 1991-06-18 Henry A. Erlich Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
CA1338457C (en) 1986-08-22 1996-07-16 Henry A. Erlich Purified thermostable enzyme
IL86724A (en) 1987-06-19 1995-01-24 Siska Diagnostics Inc Methods and kits for amplification and testing of nucleic acid sequences
US6031091A (en) * 1987-09-21 2000-02-29 Gen-Probe Incorporated Non-nucleotide linking reagents for nucleotide probes
IE61148B1 (en) 1988-03-10 1994-10-05 Ici Plc Method of detecting nucleotide sequences
JP2781438B2 (ja) 1988-10-20 1998-07-30 モーリィ,アリグザンダー,アラン 白血病及びリンパ腫におけるモノクローナリテイーの診断法
US5424413A (en) * 1992-01-22 1995-06-13 Gen-Probe Incorporated Branched nucleic acid probes
JP3595841B2 (ja) 1992-12-04 2004-12-02 サーナ セラピューティクス,インコーポレイテッド リボザイム増幅診断用薬
US6207373B1 (en) * 1998-02-25 2001-03-27 Nanogen, Inc. Methods for determining nature of repeat units in DNA
US5518884A (en) * 1994-02-28 1996-05-21 Becton, Dickinson And Company Nucleic acid sequences specific for mycbacterium kansasii
US5753439A (en) * 1995-05-19 1998-05-19 Trustees Of Boston University Nucleic acid detection methods
US5854033A (en) * 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
US5589322A (en) * 1995-12-12 1996-12-31 Eastman Kodak Company Process for making a direct dispersion of a photographically useful material
CA2239683A1 (en) * 1995-12-22 1997-07-03 Dade Behring Marburg Gmbh Homogeneous amplification and detection of nucleic acids
US5785835A (en) 1996-04-12 1998-07-28 One Lambda Electrophoresis method and devices
US5780233A (en) * 1996-06-06 1998-07-14 Wisconsin Alumni Research Foundation Artificial mismatch hybridization
US6194149B1 (en) * 1998-03-03 2001-02-27 Third Wave Technologies, Inc. Target-dependent reactions using structure-bridging oligonucleotides
US6806051B2 (en) * 2000-09-25 2004-10-19 Picoliter Inc. Arrays of partially nonhybridizing oligonucleotides and preparation thereof using focused acoustic energy
US6350580B1 (en) * 2000-10-11 2002-02-26 Stratagene Methods for detection of a target nucleic acid using a probe comprising secondary structure
US6573051B2 (en) * 2001-03-09 2003-06-03 Molecular Staging, Inc. Open circle probes with intramolecular stem structures
WO2003052116A2 (en) * 2001-07-17 2003-06-26 Stratagene Methods for detection of a target nucleic acid using multi-subunit probes
WO2003027309A2 (en) * 2001-09-24 2003-04-03 One Lambda Diagnostic probe detection system

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0450594A2 (de) * 1990-04-03 1991-10-09 David Segev Signalamplifikation einer DNS-Sonde
US20010019825A1 (en) * 1998-09-11 2001-09-06 One Lambda Method for amplification of DNA
WO2000079006A1 (en) * 1999-06-17 2000-12-28 Fred Hutchinson Cancer Research Center Oligonucleotide arrays for high resolution hla typing

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO03027309A2 *

Also Published As

Publication number Publication date
US20030165925A1 (en) 2003-09-04
US20130330725A1 (en) 2013-12-12
JP2005504281A (ja) 2005-02-10
CA2460759C (en) 2011-05-31
WO2003027309A3 (en) 2003-10-16
CN1312289C (zh) 2007-04-25
EP1430150B1 (de) 2015-08-19
EP1430150A4 (de) 2005-02-02
EP2980222A1 (de) 2016-02-03
US8512953B2 (en) 2013-08-20
AU2002327046B2 (en) 2007-11-29
US9988671B2 (en) 2018-06-05
CN1589331A (zh) 2005-03-02
CA2460759A1 (en) 2003-04-03
BR0212773A (pt) 2004-10-13
CN101074450A (zh) 2007-11-21
WO2003027309A2 (en) 2003-04-03

Similar Documents

Publication Publication Date Title
US9988671B2 (en) Diagnostic probe detection system
AU2002327046A1 (en) Diagnostic probe detection system
Guo et al. Enhanced discrimination of single nucleotide polymorphisms by artificial mismatch hybridization
US20120295808A1 (en) Solid Support Assay Systems and Methods Utilizing Non-Standard Bases
US6207379B1 (en) Method for amplification of DNA
JP2003535599A (ja) 核酸の捕捉部とその使用
EP1660679B1 (de) Selbsthybridisierende mehrfachziel-nukleinsäuresonden und verwendungsverfahren
US6500614B1 (en) Method for identifying an unknown allele
CA2405687A1 (en) Process for allele discrimation utilizing primer extension
Nilsson et al. Making ends meet in genetic analysis using padlock probes
JP2004520812A (ja) 対立遺伝子を決定するための方法
JPH10506541A (ja) Hla−dr型別判定の実施を可能するプローブ系および該プローブを用いる型別判定法
US20040014101A1 (en) Separating and/or identifying polymorphic nucleic acids using universal bases
WO1997020070A1 (en) Methods for separating and/or identifying dna molecules
EP1585835B1 (de) Nukleinsäuresonden und Verfahren zum Nachweis einer Zielnukleinsäuresequenz mit zwei oder mehr cis-Nukleinsäurebereichen
JP4731081B2 (ja) 核酸を選択的に単離するための方法
Asari et al. Enhanced discrimination of single nucleotide polymorphisms using 3′ nucleotide differences in ligase detection reaction probes
US20080311571A1 (en) Nucleic Acid Fragments for Detecting Nucleic Acid and Method for Detecting Nucleic Acid
GB2395556A (en) Nucleic acid probe
Marras 2 Artificial Hybridization Probes
US20040235004A1 (en) Methods for detection of differences in nucleic acids

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20040311

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR

AX Request for extension of the european patent

Extension state: AL LT LV MK RO SI

A4 Supplementary search report drawn up and despatched

Effective date: 20041221

17Q First examination report despatched

Effective date: 20050329

17Q First examination report despatched

Effective date: 20050329

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: ONE LAMBDA, INC.

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

INTG Intention to grant announced

Effective date: 20150410

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

REG Reference to a national code

Ref country code: AT

Ref legal event code: REF

Ref document number: 743867

Country of ref document: AT

Kind code of ref document: T

Effective date: 20150915

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 60247407

Country of ref document: DE

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 14

REG Reference to a national code

Ref country code: AT

Ref legal event code: MK05

Ref document number: 743867

Country of ref document: AT

Kind code of ref document: T

Effective date: 20150819

REG Reference to a national code

Ref country code: NL

Ref legal event code: FP

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: FI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150819

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151120

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: ES

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150819

Ref country code: SE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150819

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20151221

Ref country code: AT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150819

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150819

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150819

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150819

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150819

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150819

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

REG Reference to a national code

Ref country code: DE

Ref legal event code: R097

Ref document number: 60247407

Country of ref document: DE

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MC

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150819

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

REG Reference to a national code

Ref country code: IE

Ref legal event code: MM4A

26N No opposition filed

Effective date: 20160520

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20150930

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20150924

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20150930

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 15

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150819

REG Reference to a national code

Ref country code: DE

Ref legal event code: R082

Ref document number: 60247407

Country of ref document: DE

Representative=s name: FRIESE GOEDEN PATENTANWAELTE PARTGMBB, DE

REG Reference to a national code

Ref country code: DE

Ref legal event code: R082

Ref document number: 60247407

Country of ref document: DE

Representative=s name: FRIESE GOEDEN PATENTANWAELTE PARTGMBB, DE

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150819

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150819

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 16

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: TR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20150819

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20150924

REG Reference to a national code

Ref country code: FR

Ref legal event code: PLFP

Year of fee payment: 17

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FR

Payment date: 20210812

Year of fee payment: 20

Ref country code: NL

Payment date: 20210915

Year of fee payment: 20

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20210818

Year of fee payment: 20

Ref country code: DE

Payment date: 20210818

Year of fee payment: 20

REG Reference to a national code

Ref country code: DE

Ref legal event code: R071

Ref document number: 60247407

Country of ref document: DE

REG Reference to a national code

Ref country code: NL

Ref legal event code: MK

Effective date: 20220923

REG Reference to a national code

Ref country code: GB

Ref legal event code: PE20

Expiry date: 20220923

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GB

Free format text: LAPSE BECAUSE OF EXPIRATION OF PROTECTION

Effective date: 20220923