EP1126013A1 - Reinigungsmittel für medizinische Instrumente - Google Patents
Reinigungsmittel für medizinische Instrumente Download PDFInfo
- Publication number
- EP1126013A1 EP1126013A1 EP01100242A EP01100242A EP1126013A1 EP 1126013 A1 EP1126013 A1 EP 1126013A1 EP 01100242 A EP01100242 A EP 01100242A EP 01100242 A EP01100242 A EP 01100242A EP 1126013 A1 EP1126013 A1 EP 1126013A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- cleaning agent
- agent according
- amino acid
- cleaning
- alkyl group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/66—Non-ionic compounds
- C11D1/72—Ethers of polyoxyalkylene glycols
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/26—Organic compounds containing nitrogen
- C11D3/33—Amino carboxylic acids
Definitions
- the present invention relates to liquid detergents containing Surfactants, anti-corrosion agents and other additives that enhance cleaning as well as their use for cleaning medical instruments, in particular for cleaning flexible endoscopes.
- Endoscopes are tubular or tubular instruments that are used for examination of body cavities and hollow organs. You are with one optical system, consisting of lens and eyepiece, a lighting device and mostly flushing and suction devices as well as channels for inserting special ones Instruments.
- Flexible endoscopes (which are also called fiber endoscopes are equipped with an optical fiber, which consists of a tightly packed bundle of hair-fine and therefore highly flexible individual fibers. Due to the flexibility of the glass fibers, light and image can be used on virtually any Angle be transmitted.
- In addition to the fiber bundles and the Bowden cables for the movement of the tip are channels for water flushing and air as well as one in the Usually larger biopsy and suction channel housed at the same time.
- Endoscopy can be used on its own, for example to take tissue samples, however also in combination with other methods, such as.
- Endosonography ultrasound diagnostics
- X-ray diagnostics are in use for example X-ray contrast images of the gallbladder and bile ducts and the pancreatic duct system.
- B. as part of an endoscopic retrograde cholangiography (ERC) or an endoscopic retrograde Cholangiopancreatography (ERCP) - an X-ray contrast agent under X-ray control introduced into the duct system to be examined.
- ERP endoscopic retrograde cholangiography
- ERCP endoscopic retrograde Cholangiopancreatography
- X-ray contrast media are agents for improving the radiographic Representation of body spaces, hollow organs and vessels. You absorb X-rays either weaker (negative X-ray contrast agents) or stronger (positive x-ray contrast agent) as the surrounding body tissue.
- the radio opaque (X-ray opaque) predominantly contain positive X-ray contrast media Elements of high atomic numbers (such as iodine and barium) because of their absorbency for x-rays is larger.
- organic iodine derivatives derived from pyridines or aromatic carboxylic acids deduce used.
- Examples include iodoxamic acid [3,3 '- (4,7,10,13-tetraoxahexadecanedioyldiamino) bis (2,4,6-triiodobenzoic acid)] and lotroxinic acid [3,3 '- (3,6,9-trioxaundecanedioyldiamino) bis (2,4,6-triiodobenzoic acid)].
- infections are particularly important Microorganisms that are transmitted through the blood and mucous membranes, such as B. tuberculosis, hepatitis, HIV infections, salmonellosis, Yersinia infections, Dysentery and the like.
- the cleaning agent according to the invention can also be used dried poorly soluble aromatic halogen compounds, such as. B. X-ray contrast medium residues, detach completely from the surfaces. Because of the engagement The cleaning agents according to the invention are flexible endoscopes even after months constant use in practice microbiologically still perfect. Thereby patient safety is significantly increased and the lifespan of these high quality medical devices.
- the inventive Detergents especially for duodenoscopes, via the X-ray contrast media are preferably administered, one compared to the cleaners of the prior art Technology have much better cleaning performance. This allowed the Microbiological status of the duodenoscope (after subsequent disinfection) strong be improved.
- the nonionic surfactant or surfactants are advantageously selected from the Group of alkyl ethoxylates, the alkyl group of which is a saturated or unsaturated, straight or branched chain alkyl group having 10 to 18, preferably 12 to 14 Is carbon atoms, preferably 2 to 15, in particular 5 to, per molecule 9, especially 7 contain ethylene oxide units.
- Isotridecanol ethoxylate and / or fatty alcohol polyglycol ether are very particularly preferred.
- the total amount of nonionic surfactants from the range of 1.0 to 20.0 wt .-%, preferably from 10.0 to 15.0 wt .-% selected, each based on the total weight of the preparations.
- amino acids according to the invention are e.g. B. glutamic acid, which is characterized by the following structural formula: and / or pyrrolidone carboxylic acid (pyroglutamic acid), which is characterized by the following structural formula:
- the total amount of amino acids is advantageous from the range from 0.1 to 10.0% by weight, preferably from 0.5 to 2.0% by weight selected, each based on the total weight of the preparations.
- the cleaning agents according to the invention can also contain amphoteric surfactants.
- Amphoteric surfactants are surfactants that have both acidic and basic hydrophilic groups and thus behave acidic or basic depending on the condition.
- Advantageous for the purposes of the present invention are, for example, amphoteric surfactants based on aliphatic polyamines with carboxy, sulfo or phosphono side chains, such as R ⁇ NH ⁇ (CH 2 ) n ⁇ COOH.
- z. B. amphoteric surfactants the alkyl group of which is saturated or unsaturated, straight or branched chain alkyl group having 10 to 18, preferably Is 12 to 14 carbon atoms.
- Amphoteric surfactants from the group of amphopropionates such as, for. B. the cocobetaine amido amphopropionate, which is characterized by the following structure:
- the total amount of amphoteric surfactants in the range from 1.0 to 10.0% by weight, preferably from 2.0 to 5.0% by weight selected, based in each case on the total weight of the preparations.
- the cleaning agents according to the invention can be in the form of liquid concentrates are available and packaged in dosing bags, for example, so that a Ready-to-use solution can be freshly prepared. It is particularly advantageous if the pH of the concentrate is between 5 and 9.
- the liquid concentrates are preferably diluted with water to a working solution. Are preferred Ready-made solutions containing 0.5 to 5% by weight of cleaning agents according to the invention contain.
- the working solution preferably has a pH between 6 and 8 ⁇ m to achieve optimal protection of the sensitive material.
- the cleaning agents according to the invention can also advantageously be customary Corrosion inhibitors, such as benzotriazole, contain, especially if they when used with metallic surfaces, especially with non-refined ones Steels or materials made of non-ferrous metal alloys. It it is preferred that the content of one or more corrosion inhibitors is between 0.1 and 5% by weight, based on the total weight of the formulation.
- customary Corrosion inhibitors such as benzotriazole
- the cleaning agents according to the invention can advantageously be added Complexing agents and / or pH regulators contain the negative influence to reduce fluctuating water hardness or to ensure that the pH value of the cleaning agent is in an area that the sensitive material does not harms.
- the inventive Cleaning agents for such preparations are common preservatives, dyes, Contain fragrances and / or other usual auxiliary substances.
- the majority of these wear of the cases do not contribute to the cleaning effect, but serve for storability as well aesthetic purposes.
- the amounts of such carriers and perfume to be used can be in Dependent on the type of the respective product by the specialist by simple Trying out can be easily determined.
- a pH of 8 is set.
- a pH of 8 is set.
- a pH of 8 is set.
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Detergent Compositions (AREA)
Abstract
Description
- mindestens ein nichtionisches Tensid und
- mindestens eine Aminosäure und/oder ein Aminosäurenderivat enthalten.
- mindestens ein nichtionisches Tensid und
- mindestens eine Aminosäure und/oder ein Aminosäurenderivat enthalten, zur Reinigung empfindlicher medizinischer Instrumente, flexibler Endoskope und empfindlicher medizinischer Oberflächen.
- nichtionische Tenside: zwischen 0,005 und 1 Gew.-%
- Aminosäure: zwischen 0,0005 und 0,5 Gew.-%
- Amphotenside: zwischen 0,005 und 0,5 Gew.-%
5 % | Pyrrolidoncarbonsäure |
5 % | Isotridecanolethoxylat |
5 % | Fettalkoholpolyglykolether |
3 % | Cocobetainamido Amphopropionat |
1 % | Korrosionsschutz |
10 % | Glykol |
1 % | pH-Regulator |
Rest | Wasser |
7,5 % | Pyrrolidoncarbonsäure |
5 % | Isotridecanolethoxylat |
5 % | Fettalkoholpolyglykolether |
1 % | Korrosionsschutz |
10 % | Alkohole |
1 % | pH-Regulator |
3 % | Komplexbildner |
Rest | Wasser |
1 % | Pyrrolidoncarbonsäure |
6 % | Isotridecanolethoxylat |
6 % | Fettalkoholpolyglykolether |
2,25 % | Cocobetainamido Amphopropionat |
1 % | Korrosionsschutz |
10 % | Glykol |
2 % | pH-Regulator |
3 % | Komplexbildner |
Rest | Wasser |
Claims (13)
- Flüssiges Reinigungsmittel für medizinische Instrumente, dadurch gekennzeichnet, daß esmindestens ein nichtionisches Tensid undmindestens eine Aminosäure und/oder ein Aminosäurenderivat enthält.
- Reinigungsmittel nach Anspruch 1, dadurch gekennzeichnet, daß das oder die nichtionischen Tenside gewählt werden aus der Gruppe der Alkylethoxylate, deren Alkylgruppe eine gesättigte oder ungesättigte, gerad- oder verzweigtkettige Alkylgruppe mit 10 bis 18, vorzugsweise 12 bis 14 Kohlenstoffatomen ist.
- Reinigungsmittel nach einem der Ansprüche 1 oder 2, dadurch gekennzeichnet, daß es als Aminosäure Pyrrolidoncarbonsäure und/oder Glutaminsäure enthält.
- Reinigungsmittel nach mindestens einem der Ansprüche 1 bis 3, dadurch gekennzeichnet, daß es als nichtionisches Tensid Isotridecanolethoxylat und/oder Fettalkoholpolyglykolether enthält.
- Reinigungsmittel nach mindestens einem der Ansprüche 1 bis 4, dadurch gekennzeichnet, daß es als weitere(n) Bestandteil(e) mindestens ein Amphotensid enthält.
- Reinigungsmittel nach Anspruch 5, dadurch gekennzeichnet, daß das oder die Amphotenside gewählt werden aus der Gruppe der Amphotenside, deren Alkylgruppe eine gesättigte oder ungesättigte, gerad- oder verzweigtkettige Alkylgruppe mit 10 bis 18, vorzugsweise 12 bis 14 Kohlenstoffatomen ist.
- Reinigungsmittel nach mindestens einem der Ansprüche 5 bis 6, dadurch gekennzeichnet, daß es als Amphotensid Cocobetainamido Amphopropionat enthält.
- Reinigungsmittel nach mindestens einem der Ansprüche 5 bis 8, dadurch gekennzeichnet, daß die Menge an Amphotensid (eine oder mehrere Verbindungen) aus dem Bereich von 1,0 bis 10,0 Gew.-%, vorzugsweise von 2,0 bis 5,0 Gew.-%, jeweils bezogen auf das Gesamtgewicht der Zubereitungen, gewählt wird.
- Reinigungsmittel nach mindestens einem der Ansprüche 1 bis 8, dadurch gekennzeichnet, daß es ein oder mehrere nichtionische Tenside in einer Menge von 1,0 bis 20,0 Gew.-%, vorzugsweise von 10,0 bis 15,0 Gew.-%, jeweils bezogen auf das Gesamtgewicht der Zubereitungen, enthält.
- Reinigungsmittel nach mindestens einem der Ansprüche 1 bis 9, dadurch gekennzeichnet, daß es eine oder mehrere Aminosäuren in einer Menge von 0,1 bis 10,0 Gew.-%, vorzugsweise von 0,5 bis 2,0 Gew.-%, jeweils bezogen auf das Gesamtgewicht der Zubereitungen, enthält.
- Reinigungsmittel nach mindestens einem der Ansprüche 1 bis 10, dadurch gekennzeichnet, daß es einen pH-Wert zwischen 5 und 9 hat.
- Reinigungsmittel nach mindestens einem der Ansprüche 1 bis 11, dadurch gekennzeichnet, daß es in Form eines Konzentrats vorliegt, welches vor der Verwendung mit Wasser zu einer Gebrauchslösung verdünnt wird.
- Verwendung von flüssigen Reinigungsmitteln, welchemindestens ein nichtionisches Tensid undmindestens eine Aminosäure und/oder ein Aminosäurenderivat enthalten, zur Reinigung medizinischer Instrumente, flexibler Endoskope und medizinischer Oberflächen.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10007323A DE10007323A1 (de) | 2000-02-17 | 2000-02-17 | Reinigunsmittel für medizinische Instrumente |
DE10007323 | 2000-02-17 |
Publications (3)
Publication Number | Publication Date |
---|---|
EP1126013A1 true EP1126013A1 (de) | 2001-08-22 |
EP1126013B1 EP1126013B1 (de) | 2005-01-19 |
EP1126013B2 EP1126013B2 (de) | 2013-03-27 |
Family
ID=7631356
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP01100242A Expired - Lifetime EP1126013B2 (de) | 2000-02-17 | 2001-01-03 | Reinigungsmittel für medizinische Instrumente |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1126013B2 (de) |
AT (1) | ATE287442T1 (de) |
DE (2) | DE10007323A1 (de) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102014003484A1 (de) | 2014-03-14 | 2015-09-17 | Bode Chemie Gmbh | Reinigungsmittel für unbelebte Oberflächen mit spezieller Wirksamkeit gegen Schleim, Sekrete, Blut und Biofilme |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991013965A1 (de) | 1990-03-12 | 1991-09-19 | Henkel Kommanditgesellschaft Auf Aktien | Reinigungs- und desinfektionsmittel |
JPH0812572A (ja) * | 1994-07-01 | 1996-01-16 | Kosakai:Kk | 皮膚真菌症治療剤 |
WO1996023050A1 (en) * | 1995-01-24 | 1996-08-01 | Jeyes Group Plc | Cleansing compositions |
US5576284A (en) * | 1994-09-26 | 1996-11-19 | Henkel Kommanditgesellschaft Auf Aktien | Disinfecting cleanser for hard surfaces |
DE19603977A1 (de) * | 1996-02-05 | 1997-08-07 | Henkel Ecolab Gmbh & Co Ohg | Verfahren zur Reinigung und Desinfektion von empfindlichen medizinischen Geräten |
EP0919609A1 (de) * | 1997-10-01 | 1999-06-02 | Sysmex Corporation | Reinigungszusammensetzung für hämatologisches Analysenmessprobengerät sowie Reinigungsverfahren |
US5935920A (en) * | 1993-07-21 | 1999-08-10 | Henkel Kommanditgesellschaft Auf Aktien | Cleaner with high wetting power |
EP0969080A1 (de) * | 1998-07-03 | 2000-01-05 | Showa Denko Kabushiki Kaisha | Flüssige Reinigungsmittel |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3410956A1 (de) † | 1984-03-24 | 1985-09-26 | Henkel KGaA, 4000 Düsseldorf | Antimikrobiell wirksame substanzen, ihre herstellung und ihre verwendung |
DE4234070A1 (de) * | 1992-10-09 | 1994-04-14 | Henkel Ecolab Gmbh & Co Ohg | Reinigendes Desinfektionsmittel |
JP3686434B2 (ja) * | 1993-10-01 | 2005-08-24 | 千寿製薬株式会社 | コンタクトレンズ用剤の安定化方法 |
DE4433071C1 (de) * | 1994-09-16 | 1995-12-21 | Henkel Kgaa | Milde Detergensgemische |
GB2321252A (en) * | 1997-01-16 | 1998-07-22 | Reckitt & Colman Inc | Carpet cleaning compositions |
DE69708836D1 (de) * | 1997-03-12 | 2002-01-17 | Showa Denko Kk | Wasch- und Reinigungsmittel |
-
2000
- 2000-02-17 DE DE10007323A patent/DE10007323A1/de not_active Withdrawn
-
2001
- 2001-01-03 AT AT01100242T patent/ATE287442T1/de active
- 2001-01-03 EP EP01100242A patent/EP1126013B2/de not_active Expired - Lifetime
- 2001-01-03 DE DE50105092T patent/DE50105092D1/de not_active Expired - Lifetime
Patent Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991013965A1 (de) | 1990-03-12 | 1991-09-19 | Henkel Kommanditgesellschaft Auf Aktien | Reinigungs- und desinfektionsmittel |
US5403505A (en) * | 1990-03-12 | 1995-04-04 | Henkel Kommanditgesellschaft Auf Aktien | Cleaning and disinfecting agent containing an N-substituted propylene glutamic acid or derivative thereof, and an antimicrobially active compound |
US5935920A (en) * | 1993-07-21 | 1999-08-10 | Henkel Kommanditgesellschaft Auf Aktien | Cleaner with high wetting power |
JPH0812572A (ja) * | 1994-07-01 | 1996-01-16 | Kosakai:Kk | 皮膚真菌症治療剤 |
US5576284A (en) * | 1994-09-26 | 1996-11-19 | Henkel Kommanditgesellschaft Auf Aktien | Disinfecting cleanser for hard surfaces |
WO1996023050A1 (en) * | 1995-01-24 | 1996-08-01 | Jeyes Group Plc | Cleansing compositions |
DE19603977A1 (de) * | 1996-02-05 | 1997-08-07 | Henkel Ecolab Gmbh & Co Ohg | Verfahren zur Reinigung und Desinfektion von empfindlichen medizinischen Geräten |
WO1997028829A1 (de) | 1996-02-05 | 1997-08-14 | Henkel-Ecolab Gmbh & Co. Ohg | Verfahren zur reinigung und desinfektion von empfindlichen medizinischen geräten |
EP0919609A1 (de) * | 1997-10-01 | 1999-06-02 | Sysmex Corporation | Reinigungszusammensetzung für hämatologisches Analysenmessprobengerät sowie Reinigungsverfahren |
EP0969080A1 (de) * | 1998-07-03 | 2000-01-05 | Showa Denko Kabushiki Kaisha | Flüssige Reinigungsmittel |
Non-Patent Citations (4)
Title |
---|
A. BECK: "Wiederaufbereitung? Untersuchungen zur Wiederverwendung von Kathetern, Führungsdrähten und Angio-Endoskopen", 1993, SCHNITZTOR-VERLAG GMBH, pages: 110 - 114 |
B. MEYER; C. KLUIN: "Efficacy of glucoprotamin containing disinfectant against different species of atypical mycobacteria", JOURNAL OF HOSPITAL INFECTION, vol. 42, 1999, pages 151 - 154 |
DATABASE WPI Section Ch Week 199612, Derwent World Patents Index; Class A96, AN 1996-112632, XP002136348 * |
SEKUSEPT®PLUS, October 1992 (1992-10-01) |
Also Published As
Publication number | Publication date |
---|---|
EP1126013B2 (de) | 2013-03-27 |
EP1126013B1 (de) | 2005-01-19 |
ATE287442T1 (de) | 2005-02-15 |
DE10007323A1 (de) | 2001-08-23 |
DE50105092D1 (de) | 2005-02-24 |
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