EP1085083A4 - Kulturmedium zur kultivierung tierischer zellen und verfahren zur herstellung von proteinen durch dessen verwendung - Google Patents

Kulturmedium zur kultivierung tierischer zellen und verfahren zur herstellung von proteinen durch dessen verwendung

Info

Publication number
EP1085083A4
EP1085083A4 EP99922611A EP99922611A EP1085083A4 EP 1085083 A4 EP1085083 A4 EP 1085083A4 EP 99922611 A EP99922611 A EP 99922611A EP 99922611 A EP99922611 A EP 99922611A EP 1085083 A4 EP1085083 A4 EP 1085083A4
Authority
EP
European Patent Office
Prior art keywords
culture
culture medium
same
animal cells
producing proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP99922611A
Other languages
English (en)
French (fr)
Other versions
EP1085083B1 (de
EP1085083A1 (de
Inventor
Kazushi Shibuya
Masaru Atsumi
Shigeyuki Tsunakawa
Kaneo Nogaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of EP1085083A1 publication Critical patent/EP1085083A1/de
Publication of EP1085083A4 publication Critical patent/EP1085083A4/de
Application granted granted Critical
Publication of EP1085083B1 publication Critical patent/EP1085083B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/40—Nucleotides, nucleosides or bases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/70—Undefined extracts
    • C12N2500/80—Undefined extracts from animals

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
EP99922611A 1998-06-01 1999-06-01 Kulturmedium zur kultivierung tierischer zellen und verfahren zur herstellung von proteinen durch dessen verwendung Expired - Lifetime EP1085083B1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP15095798 1998-06-01
JP15095798 1998-06-01
PCT/JP1999/002904 WO1999063058A1 (en) 1998-06-01 1999-06-01 Media for culturing animal cells and process for producing protein by using the same

Publications (3)

Publication Number Publication Date
EP1085083A1 EP1085083A1 (de) 2001-03-21
EP1085083A4 true EP1085083A4 (de) 2002-11-27
EP1085083B1 EP1085083B1 (de) 2007-05-02

Family

ID=15508136

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99922611A Expired - Lifetime EP1085083B1 (de) 1998-06-01 1999-06-01 Kulturmedium zur kultivierung tierischer zellen und verfahren zur herstellung von proteinen durch dessen verwendung

Country Status (15)

Country Link
US (2) US6537782B1 (de)
EP (1) EP1085083B1 (de)
JP (1) JP3510858B2 (de)
KR (1) KR100430447B1 (de)
CN (1) CN1187441C (de)
AT (1) ATE361360T1 (de)
AU (1) AU744715B2 (de)
CA (1) CA2333966C (de)
DE (1) DE69935978T2 (de)
DK (1) DK1085083T3 (de)
ES (1) ES2285840T3 (de)
IL (1) IL139974A (de)
NO (2) NO326180B1 (de)
RU (2) RU2214455C2 (de)
WO (1) WO1999063058A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU736282B2 (en) 1997-03-21 2001-07-26 Chugai Seiyaku Kabushiki Kaisha A preventive or therapeutic agent for sensitized T cell- mediated diseases comprising IL-6 antagonist as an active ingredient
DE60009956T2 (de) * 1999-12-28 2005-04-28 Iso Tis N.V. Wachstumsfaktoren und l-glutamin enthaltendes zellkulturmedium
UA80091C2 (en) 2001-04-02 2007-08-27 Chugai Pharmaceutical Co Ltd Remedies for infant chronic arthritis-relating diseases and still's disease which contain an interleukin-6 (il-6) antagonist
DE10124820A1 (de) * 2001-05-21 2002-12-05 Heinrich Wieland Zusammensetzung und Verwendung von Substanzen zur Stabilisierung von schwefelhaltigen Aminosäuren im Blut
WO2003068260A1 (fr) 2002-02-14 2003-08-21 Chugai Seiyaku Kabushiki Kaisha Produits pharmaceutiques en solution contenant des anticorps
GB2401040A (en) 2003-04-28 2004-11-03 Chugai Pharmaceutical Co Ltd Method for treating interleukin-6 related diseases
EP3269738A1 (de) 2004-03-24 2018-01-17 Chugai Seiyaku Kabushiki Kaisha Subtypen des humanisiertem antikörper gegen interleukin-6-rezeptor
US7335491B2 (en) * 2004-08-27 2008-02-26 Wyeth Research Ireland Limited Production of anti-abeta
US20060094104A1 (en) 2004-10-29 2006-05-04 Leopold Grillberger Animal protein-free media for cultivation of cells
KR100679112B1 (ko) * 2004-11-17 2007-02-07 삼성정밀화학 주식회사 동물세포 배양방법
US9714410B2 (en) * 2005-01-05 2017-07-25 Chugai Seiyaku Kabushiki Kaisha Cell culture method and utilization of the same
EP3026109B1 (de) * 2005-12-08 2022-03-09 Amgen Inc. Verbesserte herstellung von glykoproteinen unter verwendung von mangan
ES2474573T3 (es) 2006-01-04 2014-07-09 Baxter International Inc Medio de cultivo celular sin oligop�ptidos
PE20091174A1 (es) 2007-12-27 2009-08-03 Chugai Pharmaceutical Co Ltd Formulacion liquida con contenido de alta concentracion de anticuerpo
US20110117087A1 (en) 2009-10-26 2011-05-19 Reinhard Franze Method for the production of a glycosylated immunoglobulin
MD191Z5 (ro) * 2010-01-21 2010-11-30 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова Mediu nutritiv pentru cultivarea celulelor de origine animală
KR101933197B1 (ko) 2010-11-08 2018-12-27 제넨테크, 인크. 피하 투여용 항―ｉｌ―6 수용체 항체
JP6563910B2 (ja) 2013-07-04 2019-08-21 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 血清サンプル中の抗薬物抗体を検出するための干渉抑制イムノアッセイ
US20160251625A1 (en) 2013-10-30 2016-09-01 The Curators Of The University Of Missouri Method for scalable skeletal muscle lineage specification and cultivation
KR20180009760A (ko) 2015-05-27 2018-01-29 아스테라스 세이야쿠 가부시키가이샤 핵산 함유 배지를 이용한 세포 배양 방법
US11484591B2 (en) 2016-02-22 2022-11-01 Ohio State Innovation Foundation Chemoprevention using controlled-release formulations of anti-interleukin 6 agents, synthetic vitamin A analogues or metabolites, and estradiol metabolites
US11033496B2 (en) 2017-03-17 2021-06-15 The Regents Of The University Of Michigan Nanoparticles for delivery of chemopreventive agents
ES2985769T3 (es) 2017-05-06 2024-11-07 Upside Foods Inc Composiciones y métodos para aumentar la densidad de cultivo de una biomasa celular dentro de una infraestructura de cultivo
US11479792B2 (en) 2017-07-13 2022-10-25 Upside Foods, Inc. Compositions and methods for increasing the efficiency of cell cultures used for food production
WO2020201362A2 (en) 2019-04-02 2020-10-08 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods of predicting and preventing cancer in patients having premalignant lesions
WO2022137357A1 (ja) 2020-12-22 2022-06-30 株式会社マルハチ村松 ペプチド、細胞増殖促進剤、タンパク質産生促進剤、培地、該ペプチドを用いた細胞増殖方法、及び、該ペプチドを用いたタンパク質産生方法
WO2023240152A1 (en) 2022-06-07 2023-12-14 Upside Foods, Inc. Engineering cell lines capable of proliferation in growth factor free media formulations
WO2024218715A1 (en) 2023-04-19 2024-10-24 Btl Healthcare Technologies A.S. Culture media based on protein hydrolysate and a process for preparing thereof
US12668774B2 (en) 2023-10-12 2026-06-30 Btl Healthcare Technologies A.S. Product, system and method of cell cultivation

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3856627A (en) * 1972-12-11 1974-12-24 Morinaga Milk Industry Co Ltd Culture medium for bacteria
JPH0239882A (ja) * 1988-07-29 1990-02-08 Japan Synthetic Rubber Co Ltd 動物細胞培養用培地
WO1995023212A1 (en) * 1994-02-23 1995-08-31 Sea Run Holdings, Inc. Method for culturing mammalian cells and insect cells in a medium containing fish serum
CN1157694A (zh) * 1996-10-15 1997-08-27 玉环县海天营养源有限公司 一种液化鱼蛋白粉的制作方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS509877B2 (de) * 1972-09-13 1975-04-16
US3962425A (en) * 1972-09-21 1976-06-08 Weyerhaeuser Company Ruminant repellent from enzymatically putrefied lipoidal material
JPH01148181A (ja) * 1987-12-07 1989-06-09 Jgc Corp グルタチオンの菌体内蓄積法
JPH0638704A (ja) * 1991-06-19 1994-02-15 Morinaga Milk Ind Co Ltd 発酵調味料及びその製造法
US5426045A (en) 1993-12-16 1995-06-20 Sea Run Holdings, Inc. Method for culturing mammalian cells in a medium containing fish serum
RU2103360C1 (ru) * 1996-07-25 1998-01-27 Инна Георгиевна Ермишина Питательная среда для культивирования клеток эукариотов и способ получения основы питательной среды - протеолитического гидролизата

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3856627A (en) * 1972-12-11 1974-12-24 Morinaga Milk Industry Co Ltd Culture medium for bacteria
JPH0239882A (ja) * 1988-07-29 1990-02-08 Japan Synthetic Rubber Co Ltd 動物細胞培養用培地
WO1995023212A1 (en) * 1994-02-23 1995-08-31 Sea Run Holdings, Inc. Method for culturing mammalian cells and insect cells in a medium containing fish serum
CN1157694A (zh) * 1996-10-15 1997-08-27 玉环县海天营养源有限公司 一种液化鱼蛋白粉的制作方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 200140, Derwent World Patents Index; AN 2001-375305 [40], XP002214165 *
PATENT ABSTRACTS OF JAPAN vol. 014, no. 197 (C - 0712) 23 April 1990 (1990-04-23) *

Also Published As

Publication number Publication date
WO1999063058A1 (en) 1999-12-09
CN1309698A (zh) 2001-08-22
ATE361360T1 (de) 2007-05-15
RU2214455C2 (ru) 2003-10-20
NO326180B1 (no) 2008-10-13
AU744715B2 (en) 2002-02-28
IL139974A (en) 2005-09-25
AU744715C (en) 1999-12-20
US6537782B1 (en) 2003-03-25
JP3510858B2 (ja) 2004-03-29
NO20006096L (no) 2001-02-01
EP1085083B1 (de) 2007-05-02
IL139974A0 (en) 2002-02-10
AU3958499A (en) 1999-12-20
CA2333966C (en) 2006-07-25
NO20006096D0 (no) 2000-11-30
RU2333242C2 (ru) 2008-09-10
CA2333966A1 (en) 1999-12-09
NO2009012I1 (no) 2009-06-15
US20030096372A1 (en) 2003-05-22
DE69935978T2 (de) 2008-01-17
US6962812B2 (en) 2005-11-08
DK1085083T3 (da) 2007-06-18
KR20010071359A (ko) 2001-07-28
ES2285840T3 (es) 2007-11-16
HK1037678A1 (en) 2002-02-15
CN1187441C (zh) 2005-02-02
EP1085083A1 (de) 2001-03-21
DE69935978D1 (de) 2007-06-14
KR100430447B1 (ko) 2004-05-10

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