EP0958364A4 - IMMUNOTHERAPY AND IMPROVED Vaccines - Google Patents
IMMUNOTHERAPY AND IMPROVED VaccinesInfo
- Publication number
- EP0958364A4 EP0958364A4 EP97912961A EP97912961A EP0958364A4 EP 0958364 A4 EP0958364 A4 EP 0958364A4 EP 97912961 A EP97912961 A EP 97912961A EP 97912961 A EP97912961 A EP 97912961A EP 0958364 A4 EP0958364 A4 EP 0958364A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- immunotherapy
- improved vaccines
- vaccines
- improved
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000009169 immunotherapy Methods 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/21—Retroviridae, e.g. equine infectious anemia virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A61K2039/55527—Interleukins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A61K2039/55527—Interleukins
- A61K2039/55533—IL-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A61K2039/55527—Interleukins
- A61K2039/55538—IL-12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
- C12N2740/16334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Oncology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Hematology (AREA)
- Transplantation (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Plant Pathology (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2861396P | 1996-10-23 | 1996-10-23 | |
US2861P | 1996-10-23 | ||
PCT/US1997/019502 WO1998017799A1 (en) | 1996-10-23 | 1997-10-23 | Immunotherapy and improved vaccines |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0958364A1 EP0958364A1 (en) | 1999-11-24 |
EP0958364A4 true EP0958364A4 (en) | 2001-10-31 |
Family
ID=21844431
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP97912961A Withdrawn EP0958364A4 (en) | 1996-10-23 | 1997-10-23 | IMMUNOTHERAPY AND IMPROVED Vaccines |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0958364A4 (ja) |
JP (3) | JP2001507216A (ja) |
KR (4) | KR20070108418A (ja) |
CN (2) | CN1257976C (ja) |
AU (1) | AU729579B2 (ja) |
BR (1) | BR9712852A (ja) |
CA (3) | CA2269074A1 (ja) |
WO (1) | WO1998017799A1 (ja) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002301344B2 (en) * | 1998-05-06 | 2005-01-13 | Association Francais Contre Les Myopathies | Use of a nuclease inhibitor or interleukin-10 (IL-10) for the preparation of a therapeutic composition for improving transfection of a polynucleotide into a cell and compositions useful in gene therapy |
EP0996739A2 (en) | 1998-05-06 | 2000-05-03 | Transgene S.A. | Improvments in gene therapy using compositions comprising a polynucleotide and a nuclease inhibitor or interleukin-10 |
AU3827699A (en) * | 1998-05-07 | 1999-11-23 | Akzo Nobel N.V. | Use of interleukin-18 as vaccine adjuvant |
US6316420B1 (en) * | 1998-07-28 | 2001-11-13 | Technion Research And Development Foundation Ltd. | DNA cytokine vaccines and use of same for protective immunity against multiple sclerosis |
KR20070053815A (ko) * | 1999-03-03 | 2007-05-25 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | 백신 및 유전자요법 조성물 및 이들의 제조 및 사용방법 |
IL145786A0 (en) | 1999-04-23 | 2002-07-25 | M & E Biotech As | Method for down-regulating il5 activity |
EA006233B1 (ru) | 1999-05-13 | 2005-10-27 | Уайт Холдингз Корпорейшн | Комбинированные адъювантные композиции для усиления иммунного ответа у позвоночного животного |
US6943152B1 (en) * | 1999-06-10 | 2005-09-13 | Merial | DNA vaccine-PCV |
WO2001048018A1 (en) * | 1999-12-27 | 2001-07-05 | University Of Manitoba | Genetic vaccines for the production of chicken egg-yolk antibodies against enterotoxigenic escherichia coli and other pathogens |
US6544780B1 (en) | 2000-06-02 | 2003-04-08 | Genphar, Inc. | Adenovirus vector with multiple expression cassettes |
US7754201B2 (en) | 2000-06-02 | 2010-07-13 | GenPhar, Inc | Method of vaccination through serotype rotation |
US7092633B2 (en) | 2000-11-14 | 2006-08-15 | University Of Texas System Board Of Regents | System and method for configuring optical circuits |
JP2002221520A (ja) * | 2001-01-29 | 2002-08-09 | Sumitomo Chem Co Ltd | 免疫型の予測方法 |
WO2002077210A2 (en) * | 2001-03-27 | 2002-10-03 | University Of Saskatchewan | Methods to culture circovirus |
KR20030012199A (ko) * | 2001-07-31 | 2003-02-12 | (주)지노첵 | 사이토카인 유전자를 유효성분으로 포함하는 dna 백신 |
AU2003214044B8 (en) * | 2002-01-17 | 2008-11-13 | Polymun Scientific Immunbiologische Forschung Gmbh | Anti-idiotypic antibody inducing HIV-1 neutralizing antibodies |
GB0223696D0 (en) * | 2002-10-14 | 2002-11-20 | Ml Lab Plc | Improved immunotherapy |
MXPA05005051A (es) | 2002-11-12 | 2006-03-10 | Albert B Deisseroth | Vacuna de vector adenoviral. |
AU2003297155B2 (en) | 2002-12-16 | 2010-03-18 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Recombinant vaccine viruses expressing IL-15 and methods of using the same |
US20040146486A1 (en) * | 2003-01-24 | 2004-07-29 | Juan Sun | Hybrid vector system for use as a vaccine |
WO2004069272A2 (en) * | 2003-02-05 | 2004-08-19 | Movecare Ltd | Adjuvant combination for use in the immunization of a mamal comprising il2 and il12 |
NZ570709A (en) * | 2003-06-13 | 2010-04-30 | Univ Pennsylvania | Nucleic acid sequences encoding and compositions comprising IgE signal peptide and/or IL-15 and methods for using the same |
US8299229B2 (en) | 2003-11-24 | 2012-10-30 | Microvax, Llc | Mucin antigen vaccine |
US8828957B2 (en) | 2003-12-11 | 2014-09-09 | Microvax, Llc | Methods for generating immunity to antigen |
WO2005058940A2 (en) | 2003-12-17 | 2005-06-30 | Wyeth | Immunogenic peptide carrier conjugates and methods of producing same |
PT2336147E (pt) | 2003-12-17 | 2014-07-16 | Janssen Alzheimer Immunotherap | Conjugados transportadores de péptidos beta imunogénicos e seus processos de produção |
GB0410220D0 (en) | 2004-05-07 | 2004-06-09 | Kirkham Lea Ann | Mutant pneumolysin proteins |
TW200613554A (en) | 2004-06-17 | 2006-05-01 | Wyeth Corp | Plasmid having three complete transcriptional units and immunogenic compositions for inducing an immune response to HIV |
CN101228272A (zh) * | 2005-04-20 | 2008-07-23 | 生物载体株式会社 | 用于治疗阿尔茨海默病的具有较高安全性的经鼻腔内给药基因疫苗 |
CA2657248C (en) | 2006-07-13 | 2018-10-30 | Wyeth | Production of glycoproteins |
CA2666317C (en) | 2006-11-03 | 2013-08-06 | Wyeth | Glycolysis-inhibiting substances in cell culture |
DK2115126T3 (en) | 2007-03-02 | 2015-05-04 | Wyeth Llc | Use of copper and glutamate in cell culture for the preparation of polypeptides |
EP2265715B1 (en) | 2008-04-04 | 2016-12-28 | The Trustees Of The University Of Pennsylvania | Vaccines and immunotherapeutics using il-28 and compositions and methods of using the same |
WO2010051820A1 (en) * | 2008-11-10 | 2010-05-14 | Aarhus Universitet | Multiplexed cytokine vaccination |
CA2760446C (en) | 2009-04-30 | 2018-01-02 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Inducible interleukin-12 |
US20130197612A1 (en) * | 2010-02-26 | 2013-08-01 | Jack W. Lasersohn | Electromagnetic Radiation Therapy |
CN102370979B (zh) * | 2011-10-10 | 2013-05-01 | 中国人民解放军第四军医大学 | 一种针对人TNF-α分子的自体疫苗的构建方法 |
MX2015000789A (es) | 2012-07-19 | 2015-05-07 | Zoetis Llc | Composiciones de virus de la gripe bovina. |
AU2013295770A1 (en) | 2012-07-27 | 2015-01-29 | Zoetis Services Llc | Tick toxin compositions |
CN114225019A (zh) * | 2013-03-15 | 2022-03-25 | 宾夕法尼亚大学理事会 | 癌疫苗及使用其的治疗方法 |
CA2904506A1 (en) * | 2013-03-15 | 2014-09-18 | Bioven 3 Limited | Self-assembling synthetic proteins |
US20160008449A1 (en) | 2013-03-15 | 2016-01-14 | Zoetis Services Llc | CROSS-PROTECTION OF BOVINES AGAINST B. trehalosi INFECTION BY A MULTI-VALENT VACCINE |
CN115141772A (zh) | 2015-08-14 | 2022-10-04 | 硕腾服务有限责任公司 | 牛支原体组合物 |
EP3402878A1 (en) | 2016-01-11 | 2018-11-21 | Zoetis Services LLC | Novel cross protective vaccine compositions for porcine epidemic diarrhea virus |
GB201703529D0 (en) | 2017-03-06 | 2017-04-19 | Cambridge Entpr Ltd | Vaccine composition |
EP3610000A1 (en) | 2017-04-13 | 2020-02-19 | Senti Biosciences, Inc. | Combinatorial cancer immunotherapy |
BR112020010499A2 (pt) | 2017-12-13 | 2020-11-24 | Inovio Pharmaceuticals, Inc. | vacinas de câncer de alvo de mesotelina e usos das mesmas |
EP3866813A4 (en) | 2018-10-17 | 2022-08-03 | Senti Biosciences, Inc. | COMBINATORY CANCER IMMUNOTHERAPY |
US11419898B2 (en) | 2018-10-17 | 2022-08-23 | Senti Biosciences, Inc. | Combinatorial cancer immunotherapy |
WO2020132595A1 (en) * | 2018-12-21 | 2020-06-25 | The Regents Of The University Of California | Il-10-containing vaccines and uses thereof |
CN110170049B (zh) * | 2019-06-01 | 2023-07-04 | 山西农业大学 | 一种用于鸡球虫病活疫苗的细胞因子基因佐剂 |
WO2023177655A1 (en) | 2022-03-14 | 2023-09-21 | Generation Bio Co. | Heterologous prime boost vaccine compositions and methods of use |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1984001575A1 (en) * | 1982-10-11 | 1984-04-26 | Nat Biolog Standards Board | Polypeptides useful in vaccination against enteroviruses |
WO1996011279A2 (en) * | 1994-10-03 | 1996-04-18 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Enhanced immune response by introduction of cytokine gene and/or costimulatory molecule b7 gene in a recombinant virus expressing system |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3751664T2 (de) * | 1986-08-01 | 1996-06-05 | Commw Scient Ind Res Org | Rekombinanter impfstoff |
US5457038A (en) * | 1988-11-10 | 1995-10-10 | Genetics Institute, Inc. | Natural killer stimulatory factor |
US5238823A (en) * | 1990-08-22 | 1993-08-24 | Veterinary Infectious Disease Organization | Interleukin-2-leukotoxin gene fusions and uses thereof |
IL112820A0 (en) * | 1994-03-07 | 1995-05-26 | Merck & Co Inc | Coordinate in vivo gene expression |
-
1997
- 1997-10-23 WO PCT/US1997/019502 patent/WO1998017799A1/en not_active Application Discontinuation
- 1997-10-23 CA CA002269074A patent/CA2269074A1/en not_active Abandoned
- 1997-10-23 BR BR9712852-0A patent/BR9712852A/pt not_active Application Discontinuation
- 1997-10-23 AU AU50022/97A patent/AU729579B2/en not_active Expired
- 1997-10-23 CN CNB97180897XA patent/CN1257976C/zh not_active Expired - Lifetime
- 1997-10-23 CN CNA2006100718690A patent/CN1868545A/zh active Pending
- 1997-10-23 KR KR1020077024846A patent/KR20070108418A/ko not_active Application Discontinuation
- 1997-10-23 EP EP97912961A patent/EP0958364A4/en not_active Withdrawn
- 1997-10-23 KR KR1020047021499A patent/KR100629835B1/ko not_active IP Right Cessation
- 1997-10-23 CA CA2751712A patent/CA2751712C/en not_active Expired - Lifetime
- 1997-10-23 JP JP51971498A patent/JP2001507216A/ja not_active Ceased
- 1997-10-23 CA CA2745736A patent/CA2745736C/en not_active Expired - Lifetime
- 1997-10-23 KR KR1020057008602A patent/KR20050053796A/ko not_active Application Discontinuation
- 1997-10-23 KR KR1019997003507A patent/KR100780158B1/ko not_active IP Right Cessation
-
2008
- 2008-02-27 JP JP2008045969A patent/JP2008194046A/ja active Pending
-
2009
- 2009-07-13 JP JP2009164572A patent/JP2009232860A/ja active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1984001575A1 (en) * | 1982-10-11 | 1984-04-26 | Nat Biolog Standards Board | Polypeptides useful in vaccination against enteroviruses |
WO1996011279A2 (en) * | 1994-10-03 | 1996-04-18 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Enhanced immune response by introduction of cytokine gene and/or costimulatory molecule b7 gene in a recombinant virus expressing system |
Non-Patent Citations (7)
Title |
---|
BRONTE V ET AL: "IL-2 ENHANCES THE FUNCTION OF RECOMBINANT POXVIRUS-BASED VACCINES IN THE TREATMENT OF ESTABLISHED PULMONARY METASTASES", JOURNAL OF IMMUNOLOGY, THE WILLIAMS AND WILKINS CO. BALTIMORE, US, vol. 154, no. 10, 15 May 1995 (1995-05-15), pages 5282 - 5292, XP002030630, ISSN: 0022-1767 * |
CHOW YEN-HUNG ET AL: "Improvement of hepatitis B virus DNA vaccines by plasmids coexpressing hepatitis B surface antigen and interleukin-2.", JOURNAL OF VIROLOGY, vol. 71, no. 1, 1997, pages 169 - 178, XP002176596, ISSN: 0022-538X * |
GREENBERGER MJ ET AL.,: "Il-12 gene therapy protects mice in lethal Klebsiella pneumonia", J IMMUNOL., vol. 157, no. 7, 1 October 1997 (1997-10-01), XP001015488 * |
IRVINE K R ET AL: "CYTOKINE ENHANCEMENT OF DNA IMMUNIZATION LEADS TO EFFECTIVE TREATMENT OF ESTABLISHED PULMONARY METASTASES", JOURNAL OF IMMUNOLOGY, THE WILLIAMS AND WILKINS CO. BALTIMORE, US, vol. 156, 1996, pages 238 - 245, XP002030631, ISSN: 0022-1767 * |
LIEU FRANCIS H L ET AL: "Transmissibility of murine stem cell virus-based retroviral vectors carrying both interleukin-12 cDNAs and a third gene: Implications for immune gene therapy.", CANCER GENE THERAPY, vol. 4, no. 3, 1997, pages 167 - 175, XP001019756, ISSN: 0929-1903 * |
See also references of WO9817799A1 * |
XIANG Z ET AL: "MANIPULATION OF THE IMMUNE RESP0NSE TO A PLASMID-ENCODED VIRAL ANTIGEN BY COINOCULATION WITH PLASMIDS EXPRESSING CYTOKINES", IMMUNITY, CELL PRESS, US, vol. 2, no. 2, 1 February 1995 (1995-02-01), pages 129 - 135, XP000670098, ISSN: 1074-7613 * |
Also Published As
Publication number | Publication date |
---|---|
JP2008194046A (ja) | 2008-08-28 |
JP2009232860A (ja) | 2009-10-15 |
KR20050008860A (ko) | 2005-01-21 |
KR20070108418A (ko) | 2007-11-09 |
KR20050053796A (ko) | 2005-06-08 |
WO1998017799A1 (en) | 1998-04-30 |
CN1242045A (zh) | 2000-01-19 |
CN1868545A (zh) | 2006-11-29 |
KR100629835B1 (ko) | 2006-09-29 |
CA2269074A1 (en) | 1998-04-30 |
CA2751712A1 (en) | 1998-04-30 |
CA2745736C (en) | 2016-11-22 |
BR9712852A (pt) | 1999-11-16 |
KR20000052710A (ko) | 2000-08-25 |
CA2745736A1 (en) | 1998-04-30 |
AU5002297A (en) | 1998-05-15 |
CA2751712C (en) | 2016-11-22 |
AU729579B2 (en) | 2001-02-01 |
JP2001507216A (ja) | 2001-06-05 |
EP0958364A1 (en) | 1999-11-24 |
CN1257976C (zh) | 2006-05-31 |
KR100780158B1 (ko) | 2007-11-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0958364A4 (en) | IMMUNOTHERAPY AND IMPROVED Vaccines | |
HUP9904549A3 (en) | Vaccines | |
EP1021185A4 (en) | DIHYDROPYRIMIDINE AND ITS USES. | |
ZA9711141B (en) | Novel ketobenzamides and their use | |
EP0958373A4 (en) | Vaccines. | |
HUP9700446A3 (en) | Oilsuspension-concentrate and using thereof | |
GB9410922D0 (en) | Vaccines | |
HUP9701586A3 (en) | Improved inactivated vaccines | |
EP0876157A4 (en) | METHODS AND COMPOSITIONS FOR PASSIVE IMMUNOTHERAPY | |
PL332631A1 (en) | Spray-crystallised products and associated methods | |
ZA9711565B (en) | Vaccine | |
EP0888126A4 (en) | ANTI-IDIOTYPICAL ANTIBODY VACCINE | |
PL331523A1 (en) | Azolotrizines and azolopyrimidines | |
GB2331521B (en) | Vaccine preparations | |
PL328334A1 (en) | Preparation and application thereof | |
GB9625968D0 (en) | Vaccine | |
ZA973824B (en) | Vaccines | |
GB9606032D0 (en) | Vaccines | |
GB9604596D0 (en) | Vaccines | |
GB9614182D0 (en) | Vaccines | |
GB9604595D0 (en) | Vaccines | |
GB9626882D0 (en) | Vaccines | |
GB9602617D0 (en) | Vaccines | |
GB9605229D0 (en) | Vaccines | |
GB9406708D0 (en) | Vaccines |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 19990505 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE |
|
RIC1 | Information provided on ipc code assigned before grant |
Free format text: 7C 12N 15/18 A, 7A 61K 48/00 B, 7A 61K 31/00 B, 7C 12N 15/86 B |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20010918 |
|
AK | Designated contracting states |
Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE |
|
17Q | First examination report despatched |
Effective date: 20020923 |
|
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C07K 14/54 20060101ALI20110211BHEP Ipc: A61K 48/00 20060101ALI20110211BHEP Ipc: C12N 15/19 20060101AFI20110211BHEP |
|
RTI1 | Title (correction) |
Free format text: ENHANCEMENT OF DNA IMMUNIZATION BY CO-EXPRESSION OF IL-12 SUBUNITS |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20110727 |