KR20070108418A - 면역 치료법 및 개량 백신 - Google Patents

면역 치료법 및 개량 백신 Download PDF

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Publication number
KR20070108418A
KR20070108418A KR1020077024846A KR20077024846A KR20070108418A KR 20070108418 A KR20070108418 A KR 20070108418A KR 1020077024846 A KR1020077024846 A KR 1020077024846A KR 20077024846 A KR20077024846 A KR 20077024846A KR 20070108418 A KR20070108418 A KR 20070108418A
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South Korea
Prior art keywords
plasmid
nucleotide sequence
operably linked
protein
cells
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KR1020077024846A
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English (en)
Korean (ko)
Inventor
종 제이. 김
빈 왕
진 디. 보이어
데이비드 비. 웨이너
벨판디 아이야부
Original Assignee
더 트러스티스 오브 더 유니버시티 오브 펜실바니아
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Application filed by 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 filed Critical 더 트러스티스 오브 더 유니버시티 오브 펜실바니아
Publication of KR20070108418A publication Critical patent/KR20070108418A/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
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    • A61K39/12—Viral antigens
    • A61K39/21—Retroviridae, e.g. equine infectious anemia virus
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61P31/14—Antivirals for RNA viruses
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
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    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
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    • A61K2039/55522—Cytokines; Lymphokines; Interferons
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55522—Cytokines; Lymphokines; Interferons
    • A61K2039/55527—Interleukins
    • A61K2039/55538—IL-12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
    • C12N2740/16334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • AIDS & HIV (AREA)
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  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
KR1020077024846A 1996-10-23 1997-10-23 면역 치료법 및 개량 백신 KR20070108418A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2861396P 1996-10-23 1996-10-23
US60/028,613 1996-10-23

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020057008602A Division KR20050053796A (ko) 1996-10-23 1997-10-23 면역 치료법 및 개량 백신

Publications (1)

Publication Number Publication Date
KR20070108418A true KR20070108418A (ko) 2007-11-09

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ID=21844431

Family Applications (4)

Application Number Title Priority Date Filing Date
KR1019997003507A KR100780158B1 (ko) 1996-10-23 1997-10-23 면역 치료법 및 개량 백신
KR1020077024846A KR20070108418A (ko) 1996-10-23 1997-10-23 면역 치료법 및 개량 백신
KR1020047021499A KR100629835B1 (ko) 1996-10-23 1997-10-23 면역 치료법 및 개량 백신
KR1020057008602A KR20050053796A (ko) 1996-10-23 1997-10-23 면역 치료법 및 개량 백신

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Application Number Title Priority Date Filing Date
KR1019997003507A KR100780158B1 (ko) 1996-10-23 1997-10-23 면역 치료법 및 개량 백신

Family Applications After (2)

Application Number Title Priority Date Filing Date
KR1020047021499A KR100629835B1 (ko) 1996-10-23 1997-10-23 면역 치료법 및 개량 백신
KR1020057008602A KR20050053796A (ko) 1996-10-23 1997-10-23 면역 치료법 및 개량 백신

Country Status (8)

Country Link
EP (1) EP0958364A4 (ja)
JP (3) JP2001507216A (ja)
KR (4) KR100780158B1 (ja)
CN (2) CN1257976C (ja)
AU (1) AU729579B2 (ja)
BR (1) BR9712852A (ja)
CA (3) CA2269074A1 (ja)
WO (1) WO1998017799A1 (ja)

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AU729579B2 (en) 2001-02-01
WO1998017799A1 (en) 1998-04-30
KR20050053796A (ko) 2005-06-08
BR9712852A (pt) 1999-11-16
EP0958364A4 (en) 2001-10-31
CN1242045A (zh) 2000-01-19
AU5002297A (en) 1998-05-15
KR20000052710A (ko) 2000-08-25
CN1257976C (zh) 2006-05-31
JP2008194046A (ja) 2008-08-28
CA2745736C (en) 2016-11-22
CA2745736A1 (en) 1998-04-30
JP2009232860A (ja) 2009-10-15
CA2269074A1 (en) 1998-04-30
CA2751712A1 (en) 1998-04-30
EP0958364A1 (en) 1999-11-24
KR20050008860A (ko) 2005-01-21
CA2751712C (en) 2016-11-22
JP2001507216A (ja) 2001-06-05
KR100780158B1 (ko) 2007-11-27
CN1868545A (zh) 2006-11-29
KR100629835B1 (ko) 2006-09-29

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