EP0936631A2 - Support pour radionuclides, procédé de fabrication et source radioactive miniaturisée - Google Patents

Support pour radionuclides, procédé de fabrication et source radioactive miniaturisée Download PDF

Info

Publication number
EP0936631A2
EP0936631A2 EP98250451A EP98250451A EP0936631A2 EP 0936631 A2 EP0936631 A2 EP 0936631A2 EP 98250451 A EP98250451 A EP 98250451A EP 98250451 A EP98250451 A EP 98250451A EP 0936631 A2 EP0936631 A2 EP 0936631A2
Authority
EP
European Patent Office
Prior art keywords
carrier material
mass
polysaccharide
miniaturized
radiation source
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98250451A
Other languages
German (de)
English (en)
Other versions
EP0936631A3 (fr
Inventor
Werner Dipl.-Ing. Schmidt
André Dr. Dipl.-Chem. Hess
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eurotope GmbH
Original Assignee
Eurotope GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eurotope GmbH filed Critical Eurotope GmbH
Publication of EP0936631A2 publication Critical patent/EP0936631A2/fr
Publication of EP0936631A3 publication Critical patent/EP0936631A3/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G4/00—Radioactive sources
    • G21G4/04—Radioactive sources other than neutron sources
    • G21G4/06—Radioactive sources other than neutron sources characterised by constructional features
    • G21G4/08—Radioactive sources other than neutron sources characterised by constructional features specially adapted for medical application

Definitions

  • the invention relates to a method for manufacturing of a new carrier material for radionuclides with one increased compared to known carrier materials Absorbance for the radioactive substances.
  • the invention also relates to the new Carrier material itself as well as miniaturized radioactive Radiation sources with increased dose rate, which under Using this material.
  • the object of the invention was therefore to miniaturize radioactive sources with an increased, for medical applications sufficient dose rate to manufacture.
  • the object of the invention is surprisingly simple by providing a modified carrier material solved with pore structure, which has an increased absorption capacity for radionuclides and according to claim 1 is manufactured.
  • the addition of a polysaccharide to the carrier material when baking out achieves a fine pore structure, whereby a enlarged inner surface arises.
  • the carrier material used for the production have an average grain diameter of 80 to 110 ⁇ m.
  • the grain diameter of the polysaccharide should be preferably ⁇ 50 ⁇ m.
  • the carrier materials used according to the invention For example, titanium dioxide, zirconium dioxide, Be aluminum oxide or silicon oxide. However, it does come generally all solid carrier materials in question, which in are able to take up radionuclides.
  • water can be added with a few Drop of a, preferably 20%, surfactant solution can be shifted for better gliding ability
  • Homogenizing the mass is carried out using conventional means such as one evacuable kneader, while also simultaneously any air pockets are removed. Should cylindrical carriers are made, so it can Forming the mass by extrusion or extrusion respectively. But also forming balls or tubes is possible with the kneadable mass. Then will the mass air-dried and then at one Temperature from 800 to 1300 ° C depending on the Carrier material until the formation of a pore structure annealed.
  • the polysaccharide is added in a deficit.
  • the ratio of carrier material to polysaccharide is between 6: 4 to 9: 1.
  • 70 to 90% by mass of titanium dioxide is preferably mixed with 30 to 10% by mass of the polysaccharide.
  • zirconium dioxide as a carrier material. If such a support is soaked in a conventional manner, for example with a 90 Sr (NO 3 ) 2 solution, dried and annealed at 1250 ° C., a strontium-90-titanate radiation source with an activity of 12-15 mCi / mm 3 can be used getting produced.
  • the activity of the radiation source can be increased further if the carrier material produced according to the invention, which has a size of 0.6 to 0.8 mm 3 for a miniaturized radiation source, is soaked in small portions with the radionuclide solution and after each impregnation step brief tempering is carried out at 800 ° C for a maximum of 30 minutes. With an activity concentration of 7.5 to 10 mCi / ⁇ l, four impregnation steps are usually sufficient to achieve an activity of the miniature radiation source of 20 mCi / per mm 3 . After the last impregnation step, tempering takes place at 1000 to 1300 ° C (depending on the carrier material) for approx. One hour.
  • the carrier impregnated with the radionuclide is in Stainless steel vessels of the same shape filled with a Provide sealing cap and laser welded.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Compositions Of Oxide Ceramics (AREA)
EP98250451A 1998-02-17 1998-12-28 Support pour radionuclides, procédé de fabrication et source radioactive miniaturisée Withdrawn EP0936631A3 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19807604 1998-02-17
DE1998107604 DE19807604C1 (de) 1998-02-17 1998-02-17 Trägermaterial für Radionuklide, Verfahren zur Herstellung desselben und miniaturisierte radioaktive Strahlungsquelle

Publications (2)

Publication Number Publication Date
EP0936631A2 true EP0936631A2 (fr) 1999-08-18
EP0936631A3 EP0936631A3 (fr) 2000-11-22

Family

ID=7858672

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98250451A Withdrawn EP0936631A3 (fr) 1998-02-17 1998-12-28 Support pour radionuclides, procédé de fabrication et source radioactive miniaturisée

Country Status (2)

Country Link
EP (1) EP0936631A3 (fr)
DE (1) DE19807604C1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111920966A (zh) * 2019-05-13 2020-11-13 深圳市大西塔科技有限公司 放射性颗粒及其制备方法和应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3334050A (en) * 1964-08-24 1967-08-01 Minnesota Mining & Mfg Organic carbonaceous matrix with radioisotope dispersed therein
US3493514A (en) * 1967-06-20 1970-02-03 Grace W R & Co Radioisotope-containing microspheres
JPS5232038B2 (fr) * 1972-04-10 1977-08-18
DE2322954C3 (de) * 1973-05-07 1981-12-17 Institut fiziki Akademii Nauk Gruzinskoj SSR, Tbilisi Verfahren zur Herstellung einer ionisierenden Strahlungsquelle
DE3337335C2 (de) * 1983-10-13 1987-01-08 Technischer Überwachungs-Verein Bayern e.V., 8000 München Jodpräparat und Verfahren zu dessen Herstellung
DE3803897A1 (de) * 1988-02-09 1989-08-10 Degussa Presslinge auf basis von pyrogen hergestelltem aluminiumoxid, verfahren zu ihrer herstellung und ihre verwendung
JP2958037B2 (ja) * 1990-03-01 1999-10-06 旭光学工業株式会社 多孔質セラミックス顆粒の製造方法
FR2693921B1 (fr) * 1992-07-24 1994-09-30 Tech Sep Support monolithe céramique pour membrane de filtration tangentielle.

Also Published As

Publication number Publication date
EP0936631A3 (fr) 2000-11-22
DE19807604C1 (de) 1999-07-29

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