Classifications

• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K31/00—Medicinal preparations containing organic active ingredients
  • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
  • A61K31/19—Carboxylic acids, e.g. valproic acid
  • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
• • A—HUMAN NECESSITIES
  • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
  • A23K—FODDER
  • A23K20/00—Accessory food factors for animal feeding-stuffs
  • A23K20/10—Organic substances
  • A23K20/111—Aromatic compounds
• • A—HUMAN NECESSITIES
  • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
  • A23K—FODDER
  • A23K50/00—Feeding-stuffs specially adapted for particular animals
  • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines

Definitions

• This invention relates to the use of compositions comprising benzoic acid for use as a medicament for animals, especially pigs, at the same time promoting growth thereof and improving the digestibility of amino acids fed to such animals.
• animal feed compositions comprising benzoic acid or salts thereof can be used to minimise the emission of odoriferous ammonia from organic wastes, especially animal excrements and manure.
• benzoic acid can be used instead of relatively expensive antibiotics for such animals and furthermore, such acid/salts have the advantage of being able to promote growth, decrease feed conversion and improve digestibility of amino acids in animal feeds.
• the present invention is a composition comprising benzoic acid or a derivative of benzoic acid capable of giving rise to free benzoic acid / ' // vivo for use as a medicament for animals Benzoic acid or a derivative thereof capable of giving rise to benzoic acid
• benzoic acid and derivatives thereof may be suitably administered to the animals as a component of the animal feed or in their drinking water.
• Specific examples of derivatives of benzoic acid which can give rise to benzoic acid /// vivo include salts of benzoic acid such as eg the alkali metal- alkaline earth metal- and ammonium benzoates.
• the amount of benzoic acid oi a derivative thereof administered to the animal is suitably such that ii is sufficient to prevent/cure any infection in the animal in its capacity as a biocide
• Such an amount is suitably in the range from 0.001 - 5% based on the total weight of each feed fed to the animal.
• This amount may. however, be higher if the function of benzoic acid or a derivative thereof is not only to act as a biocide but also to control the pH of the animal excreta fed on such a diet in order to suppress the emission of ammonia from the excreta.
• Such higher amounts are suitably limited to a maximum of about 10% based on the total animal feed composition.
• the benzo e acid/salt functions inter alia as an antibiotic, promotes growth, decreases feed conversion and improves digestibility of amino acids administered in animal feeds.
• benzoic acid or a derivative thereof may be used in combination with conventional ingredients present in an animal feed composition (diet) such as calcium carbonates, electrolytes such as eg ammonium chloride, proteins such as soya bean meal, wheat, starch, sunflower meal, corn, meat and bone meal, amino acids, animal fat, vitamins and trace minerals.
• Diet animal feed composition
• electrolytes such as eg ammonium chloride
• proteins such as soya bean meal, wheat, starch, sunflower meal, corn, meat and bone meal
• amino acids animal fat, vitamins and trace minerals.
• the ratio of the electrolyte to the benzoic acid or a derivative thereof is suitably in the range from 0.5 : 1 to 5 : 1 w/w, preferably from 1.5 : 1 to 3 : I w/w.
• Benzoic acid or a derivative thereof is particularly effective as a medicament for animals such as poultry, pigs or cattle, especially pigs.
• *-lt is a blend of Ca (25%) and a mixture of carboxylic acids (75%) - the acids and their amounts in the mixture being formic (30%). acetic (30%) propionic (30%) and citric (10%).

Landscapes

• Chemical & Material Sciences (AREA)
• Life Sciences & Earth Sciences (AREA)
• Polymers & Plastics (AREA)
• Health & Medical Sciences (AREA)
• Animal Husbandry (AREA)
• Food Science & Technology (AREA)
• Engineering & Computer Science (AREA)
• Zoology (AREA)
• Epidemiology (AREA)
• Veterinary Medicine (AREA)
• Public Health (AREA)
• General Health & Medical Sciences (AREA)
• Animal Behavior & Ethology (AREA)
• Pharmacology & Pharmacy (AREA)
• Medicinal Chemistry (AREA)
• Birds (AREA)
• Fodder In General (AREA)
• Feed For Specific Animals (AREA)

Applications Claiming Priority (3)

Publications (1)

Family

ID=10799084

Family Applications (1)

Country Status (9)

Cited By (1)

Families Citing this family (10)

Family Cites Families (9)

• 1996
  • 1996-08-27 GB GBGB9618008.8A patent/GB9618008D0/en active Pending
• 1997
  • 1997-08-19 PL PL331763A patent/PL191241B1/pl unknown
  • 1997-08-19 AU AU40277/97A patent/AU4027797A/en not_active Abandoned
  • 1997-08-19 CA CA2265046A patent/CA2265046C/en not_active Expired - Lifetime
  • 1997-08-19 KR KR10-1999-7001506A patent/KR100505971B1/ko not_active IP Right Cessation
  • 1997-08-19 EP EP97937758A patent/EP0921792A1/en not_active Ceased
  • 1997-08-19 BR BR9711977A patent/BR9711977A/pt active Search and Examination
  • 1997-08-19 CN CN97198985A patent/CN1236314A/zh active Pending
  • 1997-08-19 WO PCT/IB1997/001068 patent/WO1998008499A1/en not_active Application Discontinuation

Non-Patent Citations (1)

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